Streptomyces drozdowiczii: NEH16_32420
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Entry
NEH16_32420 CDS
T09042
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sdrz
Streptomyces drozdowiczii
Pathway
sdrz00270
Cysteine and methionine metabolism
sdrz00450
Selenocompound metabolism
sdrz00670
One carbon pool by folate
sdrz01100
Metabolic pathways
sdrz01110
Biosynthesis of secondary metabolites
sdrz01230
Biosynthesis of amino acids
sdrz04980
Cobalamin transport and metabolism
sdrz04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
sdrz00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NEH16_32420 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
NEH16_32420 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
NEH16_32420 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
NEH16_32420 (metH)
04980 Cobalamin transport and metabolism
NEH16_32420 (metH)
Enzymes [BR:
sdrz01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
NEH16_32420 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
UZK58164
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Position
complement(7174539..7178009)
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AA seq
1156 aa
AA seq
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MTAGERVAALRAALAGRVVVADGAMGTMLQAQDPTLEDFQQLEGCNEVLNVTRPDIVRSV
HDAYFAVGVDCVETNTFGANHAALGEYDIPERVHELSEAGARIAREAADAFTASTGEQRW
VLGSMGPGTKLPSLGHIRYATIRDGFQANAEGLLAGGADALIVETTQDLLQTKAGLVGAR
RAMDATGVRVPLICSLAFETTGTMLLGSDIGAALTVLEPLGIDLIGLNCSTGPAEMTEHL
RHLARHSATPLMCMPNAGLPVLGADGAYFPLGPDGLADAQQAFVRDYALALVGGCCGTTP
DHLRAVVERVRGTVPPDRTPQPEPGAASLYQTVPFRQDTAYLAIGERTNANGSKKFREAM
LEGRWDDCVEMAREQVREGAHMLDLCVDYVGRDGAADMDELAGRLGTASTLPIVLDSTEV
DVLRTGLERLGGRAVVNSVNYEDGDGPESRFAKVTQLAAEHGAALIALTIDEEGQARTVE
HKVAIAERLISDLTGTWGIRESDILIDTLTFTICTGQEESRKDGIATIGAIRELKRLHPD
VQTTLGLSNISFGLNPAARVVLNSVFLDECVKAGLDSAIVHASKILPIARLEEEQVKVAL
DLIYDRRAEGYDPLQRLMELFEGVNMKSLKEGKAEELAALPLDERLKRRIIDGEKNGLDD
DLTEALTSRKALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKAAVAFLEPHMER
AEGEEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILDAAVEHKAD
VIGMSGLLVKSTVIMKENLEELNQRKLAADYPVILGGAALTRAYVEQDLHEIYEGEVRYA
RDAFEGLRLMDALIAVKRGVPGATLPPLKQRRVPLREPKFEEPADVGRSDVAVDNPVPAP
PFWGSRVVKGIPHKEYTSWLDEAALFKGQWGLKGDTIEAEGRPRLRMWLDRLRTENLLEA
AVVHGYFPCVSKGDDLIVLDENGHERTRFTFPRQSRGRRLCLADFFRPEESGETDVVGLQ
IVTVGSKIGEATAELFASGSYRDYLELHGLSVQLAEALAEYWHARVRAGLGIAGREPDGL
DGMLRTEYQGCRYSLGYPACPDLEDRAKIADLLRPERIGVHLSEEFQLHPEQSTDAIVVH
HPEASYFNAGRAGGGR
NT seq
3471 nt
NT seq
+upstream
nt +downstream
nt
atgaccgccggggagcgggtggccgcgctccgggccgcgctcgccggccgggtggtggtg
gccgacggcgcgatgggcaccatgctccaggcccaggaccccacccttgaggacttccag
cagctggaagggtgcaacgaggtcctcaacgtgacccgccccgacatcgtgcgctcggtc
cacgacgcgtacttcgccgtcggcgtggactgcgtcgagacgaacaccttcggcgccaac
cacgcggcgctcggcgagtacgacatccccgagcgggtccacgagctgtccgaagccggt
gcgcgcatcgcccgcgaggccgccgacgcgttcaccgcgtccaccggcgagcagcgctgg
gtcctcggctccatgggcccgggcaccaagctgccctcgctcggccacatccggtacgcc
acgatccgggacggcttccaggcgaacgccgaggggctgctcgccgggggcgccgacgcg
ctgatcgtggagacgacgcaggacctcctccagacgaaggccggtctggtcggcgcgcgc
cgcgcgatggacgcgacgggggtccgggtcccgctgatctgctcgctcgccttcgagacg
accgggaccatgctcctcggctcggacatcggcgcggcgctcacggtcctggaaccgctg
ggcatcgacctgatcgggctgaactgctcgaccggccccgccgagatgaccgagcacctg
cgccacctggcccgccactccgcgaccccgctgatgtgcatgcccaacgccggtctgccg
gtgctgggcgcggacggcgcctacttcccgctcgggcccgacggcctcgcggacgcgcag
caggcgttcgtacgggactacgcgctggcgctggtcggcggctgctgcggcacgacgccg
gaccacctgcgggcggtggtggagcgggtgcgcggcaccgtgccgccggaccgcaccccg
cagccggagccgggcgcggcgtcgctctaccagacggtgccgttccgccaggacaccgcg
tacctggcgatcggtgagcgtacgaacgccaacgggtccaagaagttccgcgaggccatg
ctcgaaggccgctgggacgactgcgtggagatggcccgggagcaggtccgcgagggcgcg
cacatgctcgacctgtgcgtcgactacgtgggccgcgacggggccgccgacatggacgag
ctcgcggggcgtctcgggaccgcgtcgacgctgcccatcgtgctggactccaccgaggtg
gacgtgttgcgcaccggcctggaacggctgggcggccgggccgtcgtcaactcggtcaac
tacgaggacggggacgggcccgagtcccgcttcgccaaggtcacccaactggctgccgag
cacggcgcggcgctgatcgcgctgaccatcgacgaggagggccaggcccgcacggtcgag
cacaaggtcgccatcgccgagcgcctgatctccgatctgaccggcacctggggcatccgc
gagtcggacatcctcatcgacaccctgaccttcaccatctgcaccggtcaggaggagtcc
cgcaaggacggcatcgccaccatcggggcgatccgcgagctgaagcggctccacccggac
gtgcagacgaccctgggcctgtcgaacatctccttcggcctgaacccggccgcccgcgtc
gtgctcaactcggtcttcctggacgagtgcgtgaaggcgggcctggattcggccatcgtg
cacgcgtcgaagatcctgccgatcgcccggctcgaagaggagcaggtcaaggtcgcgctg
gacctgatctacgaccggcgcgccgagggctacgaccccctccagaggctcatggagctg
ttcgagggcgtcaacatgaagtcgctcaaggagggcaaggccgaggagctggccgccctg
ccgctggacgaacggctcaagcggcggatcatcgacggcgagaagaacggcctggacgac
gacctcaccgaggcgctgaccagccgcaaggccctggacatcgtcaacgacacgctgctg
gacggcatgaaggtcgtgggcgagctgttcggctccgggcagatgcagctgccgttcgtc
ctccagtccgccgaggtcatgaaggccgcggtggcgttcctcgaaccgcacatggagcgg
gccgagggcgaggagggcaagggcaccatcgtgctggccaccgtccgcggcgacgtccac
gacatcggcaagaacctcgtcgacatcatcctctccaacaacggctacaacgtggtcaac
ctgggcatcaagcagcccgtttcggccatcctcgacgcggccgtggagcacaaggcggac
gtcatcgggatgtcggggctcctcgtcaagtccacggtgatcatgaaggagaacctggag
gagctgaaccagcgcaagctggccgccgactacccggtgatcctcggtggtgccgcgctc
acccgcgcctacgtggagcaggacctgcacgagatctacgagggcgaggtgcgctacgcg
cgcgacgccttcgagggcctgcgcctgatggacgcgctcatcgccgtgaagcgcggagtg
ccgggtgccaccctgcccccgctcaagcagcgccgcgtaccgctgagggagccgaagttc
gaggagccggcggacgtgggccggtcggacgtcgccgtcgacaaccccgtccccgccccg
ccgttctggggcagccgggtcgtcaagggcatcccgcacaaggagtacacctcctggctg
gacgaggccgccctgttcaaggggcagtgggggctgaagggcgacacgatcgaggcggag
ggccggccgaggctgcggatgtggctggaccggctgcgtacggagaacctgctcgaagcg
gccgtcgtgcacggctacttcccgtgcgtgtccaagggcgacgacctgatcgtcctggac
gagaacgggcacgagcggacccggttcaccttcccccgccagtcgcgcggccgccgcctg
tgcctggcggacttcttccggcccgaggagtccggcgagacggacgtggtcgggctccag
atcgtgaccgtcggctcgaagatcggcgaggccaccgcggagctgttcgcctccggctcg
taccgcgactacctcgaactccacgggctctccgtgcagctggcggaggcgctggccgag
tactggcacgcgcgcgtccgcgccggactggggatcgccggccgcgaacccgacggcctg
gacggcatgctgcgcaccgagtaccagggctgccgctactcgctgggctacccggcctgc
ccggacctggaggaccgcgccaagatcgcggacctgctgcggccggagcggatcggggtg
cacctgtccgaggagttccagctccacccggagcagtccaccgacgcgatcgtcgtccac
caccccgaggcgtcgtacttcaacgcggggcgggccgggggtggccggtga
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