KEGG   Streptomyces drozdowiczii: NEH16_32420
Entry
NEH16_32420       CDS       T09042                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
sdrz  Streptomyces drozdowiczii
Pathway
sdrz00270  Cysteine and methionine metabolism
sdrz00450  Selenocompound metabolism
sdrz00670  One carbon pool by folate
sdrz01100  Metabolic pathways
sdrz01110  Biosynthesis of secondary metabolites
sdrz01230  Biosynthesis of amino acids
sdrz04980  Cobalamin transport and metabolism
sdrz04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:sdrz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    NEH16_32420 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    NEH16_32420 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NEH16_32420 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    NEH16_32420 (metH)
   04980 Cobalamin transport and metabolism
    NEH16_32420 (metH)
Enzymes [BR:sdrz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     NEH16_32420 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: UZK58164
LinkDB
Position
complement(7174539..7178009)
AA seq 1156 aa
MTAGERVAALRAALAGRVVVADGAMGTMLQAQDPTLEDFQQLEGCNEVLNVTRPDIVRSV
HDAYFAVGVDCVETNTFGANHAALGEYDIPERVHELSEAGARIAREAADAFTASTGEQRW
VLGSMGPGTKLPSLGHIRYATIRDGFQANAEGLLAGGADALIVETTQDLLQTKAGLVGAR
RAMDATGVRVPLICSLAFETTGTMLLGSDIGAALTVLEPLGIDLIGLNCSTGPAEMTEHL
RHLARHSATPLMCMPNAGLPVLGADGAYFPLGPDGLADAQQAFVRDYALALVGGCCGTTP
DHLRAVVERVRGTVPPDRTPQPEPGAASLYQTVPFRQDTAYLAIGERTNANGSKKFREAM
LEGRWDDCVEMAREQVREGAHMLDLCVDYVGRDGAADMDELAGRLGTASTLPIVLDSTEV
DVLRTGLERLGGRAVVNSVNYEDGDGPESRFAKVTQLAAEHGAALIALTIDEEGQARTVE
HKVAIAERLISDLTGTWGIRESDILIDTLTFTICTGQEESRKDGIATIGAIRELKRLHPD
VQTTLGLSNISFGLNPAARVVLNSVFLDECVKAGLDSAIVHASKILPIARLEEEQVKVAL
DLIYDRRAEGYDPLQRLMELFEGVNMKSLKEGKAEELAALPLDERLKRRIIDGEKNGLDD
DLTEALTSRKALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKAAVAFLEPHMER
AEGEEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILDAAVEHKAD
VIGMSGLLVKSTVIMKENLEELNQRKLAADYPVILGGAALTRAYVEQDLHEIYEGEVRYA
RDAFEGLRLMDALIAVKRGVPGATLPPLKQRRVPLREPKFEEPADVGRSDVAVDNPVPAP
PFWGSRVVKGIPHKEYTSWLDEAALFKGQWGLKGDTIEAEGRPRLRMWLDRLRTENLLEA
AVVHGYFPCVSKGDDLIVLDENGHERTRFTFPRQSRGRRLCLADFFRPEESGETDVVGLQ
IVTVGSKIGEATAELFASGSYRDYLELHGLSVQLAEALAEYWHARVRAGLGIAGREPDGL
DGMLRTEYQGCRYSLGYPACPDLEDRAKIADLLRPERIGVHLSEEFQLHPEQSTDAIVVH
HPEASYFNAGRAGGGR
NT seq 3471 nt   +upstreamnt  +downstreamnt
atgaccgccggggagcgggtggccgcgctccgggccgcgctcgccggccgggtggtggtg
gccgacggcgcgatgggcaccatgctccaggcccaggaccccacccttgaggacttccag
cagctggaagggtgcaacgaggtcctcaacgtgacccgccccgacatcgtgcgctcggtc
cacgacgcgtacttcgccgtcggcgtggactgcgtcgagacgaacaccttcggcgccaac
cacgcggcgctcggcgagtacgacatccccgagcgggtccacgagctgtccgaagccggt
gcgcgcatcgcccgcgaggccgccgacgcgttcaccgcgtccaccggcgagcagcgctgg
gtcctcggctccatgggcccgggcaccaagctgccctcgctcggccacatccggtacgcc
acgatccgggacggcttccaggcgaacgccgaggggctgctcgccgggggcgccgacgcg
ctgatcgtggagacgacgcaggacctcctccagacgaaggccggtctggtcggcgcgcgc
cgcgcgatggacgcgacgggggtccgggtcccgctgatctgctcgctcgccttcgagacg
accgggaccatgctcctcggctcggacatcggcgcggcgctcacggtcctggaaccgctg
ggcatcgacctgatcgggctgaactgctcgaccggccccgccgagatgaccgagcacctg
cgccacctggcccgccactccgcgaccccgctgatgtgcatgcccaacgccggtctgccg
gtgctgggcgcggacggcgcctacttcccgctcgggcccgacggcctcgcggacgcgcag
caggcgttcgtacgggactacgcgctggcgctggtcggcggctgctgcggcacgacgccg
gaccacctgcgggcggtggtggagcgggtgcgcggcaccgtgccgccggaccgcaccccg
cagccggagccgggcgcggcgtcgctctaccagacggtgccgttccgccaggacaccgcg
tacctggcgatcggtgagcgtacgaacgccaacgggtccaagaagttccgcgaggccatg
ctcgaaggccgctgggacgactgcgtggagatggcccgggagcaggtccgcgagggcgcg
cacatgctcgacctgtgcgtcgactacgtgggccgcgacggggccgccgacatggacgag
ctcgcggggcgtctcgggaccgcgtcgacgctgcccatcgtgctggactccaccgaggtg
gacgtgttgcgcaccggcctggaacggctgggcggccgggccgtcgtcaactcggtcaac
tacgaggacggggacgggcccgagtcccgcttcgccaaggtcacccaactggctgccgag
cacggcgcggcgctgatcgcgctgaccatcgacgaggagggccaggcccgcacggtcgag
cacaaggtcgccatcgccgagcgcctgatctccgatctgaccggcacctggggcatccgc
gagtcggacatcctcatcgacaccctgaccttcaccatctgcaccggtcaggaggagtcc
cgcaaggacggcatcgccaccatcggggcgatccgcgagctgaagcggctccacccggac
gtgcagacgaccctgggcctgtcgaacatctccttcggcctgaacccggccgcccgcgtc
gtgctcaactcggtcttcctggacgagtgcgtgaaggcgggcctggattcggccatcgtg
cacgcgtcgaagatcctgccgatcgcccggctcgaagaggagcaggtcaaggtcgcgctg
gacctgatctacgaccggcgcgccgagggctacgaccccctccagaggctcatggagctg
ttcgagggcgtcaacatgaagtcgctcaaggagggcaaggccgaggagctggccgccctg
ccgctggacgaacggctcaagcggcggatcatcgacggcgagaagaacggcctggacgac
gacctcaccgaggcgctgaccagccgcaaggccctggacatcgtcaacgacacgctgctg
gacggcatgaaggtcgtgggcgagctgttcggctccgggcagatgcagctgccgttcgtc
ctccagtccgccgaggtcatgaaggccgcggtggcgttcctcgaaccgcacatggagcgg
gccgagggcgaggagggcaagggcaccatcgtgctggccaccgtccgcggcgacgtccac
gacatcggcaagaacctcgtcgacatcatcctctccaacaacggctacaacgtggtcaac
ctgggcatcaagcagcccgtttcggccatcctcgacgcggccgtggagcacaaggcggac
gtcatcgggatgtcggggctcctcgtcaagtccacggtgatcatgaaggagaacctggag
gagctgaaccagcgcaagctggccgccgactacccggtgatcctcggtggtgccgcgctc
acccgcgcctacgtggagcaggacctgcacgagatctacgagggcgaggtgcgctacgcg
cgcgacgccttcgagggcctgcgcctgatggacgcgctcatcgccgtgaagcgcggagtg
ccgggtgccaccctgcccccgctcaagcagcgccgcgtaccgctgagggagccgaagttc
gaggagccggcggacgtgggccggtcggacgtcgccgtcgacaaccccgtccccgccccg
ccgttctggggcagccgggtcgtcaagggcatcccgcacaaggagtacacctcctggctg
gacgaggccgccctgttcaaggggcagtgggggctgaagggcgacacgatcgaggcggag
ggccggccgaggctgcggatgtggctggaccggctgcgtacggagaacctgctcgaagcg
gccgtcgtgcacggctacttcccgtgcgtgtccaagggcgacgacctgatcgtcctggac
gagaacgggcacgagcggacccggttcaccttcccccgccagtcgcgcggccgccgcctg
tgcctggcggacttcttccggcccgaggagtccggcgagacggacgtggtcgggctccag
atcgtgaccgtcggctcgaagatcggcgaggccaccgcggagctgttcgcctccggctcg
taccgcgactacctcgaactccacgggctctccgtgcagctggcggaggcgctggccgag
tactggcacgcgcgcgtccgcgccggactggggatcgccggccgcgaacccgacggcctg
gacggcatgctgcgcaccgagtaccagggctgccgctactcgctgggctacccggcctgc
ccggacctggaggaccgcgccaagatcgcggacctgctgcggccggagcggatcggggtg
cacctgtccgaggagttccagctccacccggagcagtccaccgacgcgatcgtcgtccac
caccccgaggcgtcgtacttcaacgcggggcgggccgggggtggccggtga

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