Streptomyces durmitorensis: M4V62_15175
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Entry
M4V62_15175 CDS
T08503
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sdur
Streptomyces durmitorensis
Pathway
sdur00020
Citrate cycle (TCA cycle)
sdur00630
Glyoxylate and dicarboxylate metabolism
sdur00785
Lipoic acid metabolism
sdur01100
Metabolic pathways
sdur01110
Biosynthesis of secondary metabolites
sdur01120
Microbial metabolism in diverse environments
sdur01200
Carbon metabolism
sdur01210
2-Oxocarboxylic acid metabolism
Module
sdur_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sdur_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sdur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
M4V62_15175
00630 Glyoxylate and dicarboxylate metabolism
M4V62_15175
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M4V62_15175
Enzymes [BR:
sdur01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
M4V62_15175
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
M4V62_15175
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
M4V62_15175
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
M4V62_15175
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UQT56332
UniProt:
A0ABY4PSC1
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All DBs
Position
3432127..3435921
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AA seq
1264 aa
AA seq
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MSSQSPSSSSISTDQDGQGKSPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAGASPAAAPAKPAGDAAAGAAATTSPAAPAAPAAAPAAPAAPAAPAAKPAAAAAPAPAA
KPAAAKPAAKAEPATPAETAPAGPEYVTLRGPAAAVAKNMNASVEVPTATSVRAVPVKLL
FDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFVQKDGKPTLVKPEHINF
GLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKLGMDDFTGVTVSLT
NPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRV
IQGAASGEFLRIVANLLLGENDFYDEIFKALRIPYEPVRWLKDIDASHDDDVTKAARVFE
LIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSMMKLRDV
LGVLRDSYCRTTGIEFMHIQDPKQRKWLQDRIERTHASKPEREEQLRILRRLNAAEAFET
FLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSY
AQIFREFEGNMDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLETVDPIIEG
IVRAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQ
VGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRIARLAFEFRQAFNKDVVIDL
ICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQ
LEKVFTEVREAISQPAEAEVPAPEAEFPVNVDTSISQEVVKRIAESQVNIPDRVTVHPRL
LPQLQRRMSMVEEGTIDWGMGETLAIGSLLLEGTPVRLSGQDSRRGTFGQRHAVLIDRET
GEDFTPLLYLSEDQARYNVYDSLLSEYAVMGFEYGYSLARPESLVMWEAQFGDFVNGAQT
VVDEYISAAEQKWNQHSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAMPTLPS
NYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKTEEFTTGGFRPVIGDDSVEASAVRK
VVFCSGKLYYDLEAERKKREVTDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLWAQEEP
ANQGAWPFIALNLIDHLDLAVGADIPHGERLRRISRPHGSSPAVGSKKRHEQEQEQLLTE
VFEA
NT seq
3795 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtcacagtcccccagtagctcgagcatctcgaccgaccaagacgggcaaggcaag
agccctgctgctgccttcggtcccaatgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtcgaccgagcctggtgggacttcttcgccgactacaagccg
ggagcgggcgcgtcacctgccgctgccccggccaagccggcgggtgacgcagccgcgggg
gctgcggccaccacgtcccccgcagctcctgccgcacccgccgccgccccggccgcaccc
gccgcgcccgccgctcctgcggcgaagcccgcagccgccgcggccccggcccccgccgcg
aagcccgcagccgcgaagcccgccgccaaggcggagcccgcgacccctgctgaaacggcc
ccggcaggacccgagtacgtgacgctgcgcggccccgccgccgcggtcgcgaagaacatg
aacgcctccgtggaggtcccgacggcgacgtcggtccgcgcggtcccggtgaagctgctc
ttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcccgcggcgggaagatctcc
ttcacgcacctcatcgggtacgcgatggtgcaggccatcaaggccatgccgtcgatgaac
tactccttcgtgcagaaggacggcaagccgacgctggtcaagccggagcacatcaacttc
ggcctcgccatcgacctggtgaagcccaacggcgaccgccagctcgtggtcgcgggcatc
aagaaggccgagaccctgaacttcttcgagttctggcaggcctacgaggacatcgtccgc
cgtgcacgcgacggcaagctcggcatggacgacttcaccggcgtcacggtctcgctgacc
aaccccggcggcctcggcacggtccactcggtcccccgcctgatgcccggacagtcggtc
atcatgggcgtcggctcgatggactaccccgcggagttccagggcacgtcccaggacacc
ctgaacaagctcggcatctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtg
atccagggcgccgcttcgggtgagttcctgcggatcgtcgcgaacctgctgctcggcgag
aacgacttctacgacgagatcttcaaggcgctgcgcatcccgtacgagccggtccgctgg
ctcaaggacatcgacgcctcgcacgacgacgacgtcacgaaggccgcccgcgtcttcgag
ctgatccactcctaccgcgtccgcggccacgtcatggccgacacggacccgctggagtac
aagcagcgcaagcaccccgacctggacatcaccgagcacggcctcaccttgtgggacctg
gagcgcgagttcgcggtcggcggcttcgccggcaagtcgatgatgaagctgcgcgacgtc
ctcggcgtcctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcacatccag
gacccgaagcagcgcaagtggctccaggaccgcatcgagcgcacgcacgcctcgaagccc
gagcgcgaggagcagctgcgcatcctgcgtcggctgaacgccgccgaggccttcgagacg
ttcctgcagacgaagtacgtcggccagaagcgcttctccctggagggcggcgagtccgtc
atcccgctgctcgacgccgtcatcgacagcgccgccgagtcccgcctggacgaggtcgtc
atcggcatggcccaccgcggccgcctgaacgtcctcgcgaacatcgtgggcaagtcgtac
gcccagatcttccgcgagttcgagggcaacatggaccccaagtccatgcacggctccggc
gacgtgaagtaccacctgggcgccgagggcaccttcaccggcctcgacggcgagcagatc
aaggtctcgctcgcggcgaacccgtcccacctggagacggtcgacccgatcatcgagggc
atcgtccgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtcctgccc
gtcgccctgcacggtgacgcggccttcgcgggccagggtgtggtcgccgagacgctgaac
atgtcgcagctgcgcggttaccgcacgggcggcacggtccacatcgtcatcaacaaccag
gtcggcttcaccgccgccccggagtcgtcgcgctcctccatgtacgccacggacgtggcc
cgcatgatcgaggcgccgatcttccacgtgaacggcgacgaccccgaggccgtcgtgcgc
atcgcgcggctcgctttcgagttccgtcaggcgttcaacaaggacgtcgtgatcgacctc
atctgctaccgccgccgcggtcacaacgagtcggacaacccggcgttcacgcagccgctg
atgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctcatc
ggtcgcggcgacatcaccctggaagaggccgagcaggcgctccaggacttccaggggcag
ctggagaaggtcttcacggaggtccgcgaggccatctcgcagcccgccgaggccgaggtc
ccggccccggaggccgagttcccggtgaacgtcgacacgtcgatctcccaggaggtcgtc
aagcggatcgccgagtcccaggtcaacatccccgaccgggtcaccgtccacccgcgtctg
ctgccgcagttgcagcgccgcatgtcgatggtcgaggaaggcacgatcgactggggcatg
ggcgagaccctcgccatcggttcgctgctgctcgaaggcacgccggtccgtctgtcgggc
caggactcgcgccgtggcacgttcggtcagcgtcacgcggtcctcatcgaccgtgagacg
ggcgaggacttcacgccgctcctgtacctctccgaggaccaggcgcgctacaacgtctac
gactcgctgctctccgagtacgcggtgatgggcttcgagtacggctactcgctggcccgt
cccgagtccctcgtcatgtgggaagcgcagttcggtgacttcgtcaacggcgcgcagacg
gtggtggacgagtacatctcggccgccgagcagaagtggaaccagcactccggcgtcacg
ctgctgctgccgcacggctacgagggccagggcccggaccactcgtccgcccgcatcgag
cgcttcctccagctgtgcgcgcagaacaacatgacggtcgcgatgccgacccttccgtcg
aactacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtggtc
ttcacgccgaagtcgatgctgcgcctcaaggcggcggcctcgaagacggaggagttcacg
acgggtggcttccgcccggtcatcggcgacgactcggtcgaggcgtcggcggtccgcaag
gtcgtcttctgctccggcaagctgtactacgacctggaggccgagcggaagaagcgcgag
gtcacggacaccgcgatcatccgcatcgagcgtctgtacccgctgccgggtgccgagctc
caggcggagatcgcgaagtacccgaacgccgagaagtacctgtgggcgcaggaggagccg
gcgaaccagggcgcgtggcccttcatcgccctcaacctcatcgaccacctggacctggcg
gtcggcgcggacatcccgcacggcgagcgcctgcgccgcatctcgcggccgcacggctcg
tcccccgcggtcggttcgaagaagcgccacgagcaggagcaggagcagctcctcaccgag
gtcttcgaggcgtga
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