Streptomyces durmitorensis: M4V62_28980
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Entry
M4V62_28980 CDS
T08503
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sdur
Streptomyces durmitorensis
Pathway
sdur00010
Glycolysis / Gluconeogenesis
sdur00020
Citrate cycle (TCA cycle)
sdur00620
Pyruvate metabolism
sdur00785
Lipoic acid metabolism
sdur01100
Metabolic pathways
sdur01110
Biosynthesis of secondary metabolites
sdur01120
Microbial metabolism in diverse environments
sdur01200
Carbon metabolism
sdur01210
2-Oxocarboxylic acid metabolism
Module
sdur_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sdur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
M4V62_28980 (aceE)
00020 Citrate cycle (TCA cycle)
M4V62_28980 (aceE)
00620 Pyruvate metabolism
M4V62_28980 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M4V62_28980 (aceE)
Enzymes [BR:
sdur01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
M4V62_28980 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
RL
Motif
Other DBs
NCBI-ProteinID:
UQT58768
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Position
complement(6501297..6504029)
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AA seq
910 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKVLNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQIFFQGHASPGIYARAFLLDRLSEQQLDAFRQ
EKSKAPNGLSSYPHPRLMPDFWEFPTVSMGLGPLGAIFQARMNRYMEARGIADTSKSHVW
AYLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESQFRGA
GWNVIKLVWDRSWDPLLAQDRDGVLVNRLNTTPDGQFQTYATETGSYIREHFFGDDHRLR
AMVENMSDEQILHLGRGGHDHKKVYAAYAAAKAHKGQPTVILAQTVKGWTLGPNFEGRNA
THQMKKLTADDLKGFRDRLHIPITDKELEGGAPPYYHPGRDSEEIQYMHDRRQGLGGYVP
TRVVRSKPLQLPEDKTYATAKKGSGQQSIATTMAFVRILKDLMRDKEIGKRFVLIAPDEY
RTFGMDAFFPSAKIYNPLGQQYEAVDRELLLAYKESPTGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMADQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAFGYEIAHIVKDGLRRMYGPDSEDVFYYLTVYNEPIQHPAEPA
DVDVDGILKGIHRFKAGEQGAIPAQILASGVAVPWAVEAQQILASEWNVKADVWSATSWN
ELRREAVDVERHNLLHPEEEQRVPYVTQKLSGAEGPFVAVSDWMRSVPDQISRWVPGTYQ
SLGADGFGFADTRGAARRFFHIDAQSIVVGVLTELAREGKVDRSVLKQAIDRYQLLDVTA
ADPGAAGGDA
NT seq
2733 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggcctgccgagtcaggtcccg
gacttcgatcccgaagagacccaggagtggctcgactccctcgatgccgcggtcgacgaa
cgcggccgcgagcgggcccgctacctgatgctccggctcatcgaacgtgcgcgcgagaag
cgtgtggctgtgcccgagatgcgcagcacggactacgtcaacacgatcgccaccaaggac
gagccgttcttccccggcaacgaggagatcgagcgcaaggtcctgaacgcgacccgctgg
aacgccgcggtgatggtgtcgcgcgcccagcgtcccggcatcggggtcggcggtcacatc
gccaccttcgcctcgtcggcctcgctctacgacgtgggcttcaaccacttcttccgtggc
aaggacgagggcgacggcggcgaccagatcttcttccaggggcacgcgtcccccggtatc
tacgcccgcgccttcctcctggaccggctctccgagcagcagctcgacgcgttccgccag
gagaagtcgaaggcaccgaacgggctctcgtcctacccgcacccgcgtctgatgccggac
ttctgggagttcccgaccgtctccatgggcctcggcccgctcggcgcgatcttccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgccgacacctccaagtcgcacgtctgg
gcctacctcggcgacggcgagatggacgagcccgagtcgctcggccagctctccatcgcc
gcccgcgagggcctggacaacctgaccttcgtcgtcaactgcaacctccagcgcctcgat
ggcccggtgcgcggcaacggcaagatcatccaggagctggagtcgcagttccgcggcgcc
ggctggaacgtcatcaagctggtctgggaccgcagttgggacccgctgctcgcgcaggac
cgcgacggcgtcctggtcaaccggctcaacacgacgcccgacggccagttccagacgtac
gcgaccgagaccggctcgtacatccgcgagcacttcttcggcgacgaccaccgcctgcgc
gccatggtcgagaacatgtccgacgagcagatcctgcacctgggccgcggcggccacgac
cacaagaaggtctacgcggcgtacgcggccgccaaggcccacaagggccagccgaccgtc
atcctggcgcagacggtcaagggctggaccctcggcccgaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggccgacgacctcaagggcttccgcgaccgtctgcac
atcccgatcacggacaaggagctggagggcggcgccccgccgtactaccaccccggccgt
gactcggaagagatccagtacatgcacgaccgccgccagggcctcggcggttatgtcccg
acccgagtggtccgctcgaagcccctccagcttcccgaggacaagacgtacgcgaccgcg
aagaagggttcgggccagcagtcgatcgccaccaccatggcgttcgtccgcatcctgaag
gacctcatgcgggacaaggagatcggcaagcgcttcgtgctgatcgcccccgacgagtac
cgcaccttcggcatggacgccttcttcccgagcgcgaagatctacaacccgctcggccag
cagtacgaggccgtcgaccgcgagctgctcctggcctacaaggagtccccgaccggccag
atgctgcacgacggcatctcggaggcaggctgcacggcgtccctcatcgccgcgggctcg
gcctacgccacccacggcgaacccctgatcccggtctacgtcttctactcgatgttcggt
ttccagcgcaccggcgaccagttctggcagatggccgaccagctggcccgcggcttcgtc
ctcggcgccaccgccggccgcacgacactgaccggcgagggcctccagcacgcggacggc
cactcgcagctgctcgcctcgaccaacccgggctgcgtcgcctacgacccggccttcggc
tacgagatcgcgcacatcgtcaaggacggcctgcgccggatgtacggccccgacagcgag
gacgtcttctactacctcaccgtctacaacgagccgatccagcacccggccgagcccgcc
gatgtggacgtcgacggcatcctcaagggcatccaccgcttcaaggcgggcgagcagggc
gccatcccggcgcagatcctcgcctccggtgtcgcggtcccgtgggcggtcgaggcccag
cagatcctcgcttcggagtggaacgtcaaggcggacgtctggtcggcgacctcctggaac
gaactgcgccgcgaggcggtagacgtggagcgccacaacctcctgcaccccgaggaggag
cagcgcgtcccgtacgtgacgcagaagctctccggcgccgagggcccgttcgtggccgtc
tccgactggatgcggagcgtccccgaccagatctcccgctgggtccccggcacgtaccag
tccctgggcgccgacggcttcggcttcgcggacacccgcggtgctgcccgccgcttcttc
cacatcgacgcgcagtcgatcgtggtcggtgtgctgaccgagctggcccgcgagggcaag
gtcgaccgctccgtactgaagcaggccatcgaccgctaccagctcctggacgtcacggcg
gccgacccgggcgccgctgggggcgacgcctag
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