Streptomyces durmitorensis: M4V62_33720
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Entry
M4V62_33720 CDS
T08503
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sdur
Streptomyces durmitorensis
Pathway
sdur00270
Cysteine and methionine metabolism
sdur00450
Selenocompound metabolism
sdur00670
One carbon pool by folate
sdur01100
Metabolic pathways
sdur01110
Biosynthesis of secondary metabolites
sdur01230
Biosynthesis of amino acids
sdur04980
Cobalamin transport and metabolism
sdur04981
Folate transport and metabolism
Module
sdur_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sdur00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
M4V62_33720 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
M4V62_33720 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
M4V62_33720 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
M4V62_33720 (metH)
04980 Cobalamin transport and metabolism
M4V62_33720 (metH)
Enzymes [BR:
sdur01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
M4V62_33720 (metH)
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GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
UQT59625
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Position
7544709..7548227
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AA seq
1172 aa
AA seq
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MASLPTPSSGLHDGTRVEALREALATRVVVADGAMGTMLQAQDPTLEDFQNLEGCNEILN
VTRPDIVRSVHEEYFAVGVDCVETNTFGTNFAALSEYDITERNHELSEAGARIAREVADE
FTAKTGQQRWVLGSMGPGTKLPTLGHAPYTTLRDAYQINAEGMIAGGADALLVETTQDLL
QTKSAILGARRALEATGTSLPLICSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCA
TGPAEMSEHLRYLARHSRVPISCMPNAGLPVLGKNGAHYPLTEAELADAQETFVREYGLS
LVGGCCGTTPEHLRQVVERVRGVETVRREPHPEPGAASLYQTVPFRQDTAYMAIGERTNA
NGSKKFREAMLDARWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMAELAGRFATAST
LPIVLDSTELPVIQAGLEKLGGRAVINSVNYEDGDGPESRFAKVTALAKEHGAALIALTI
DEEGQARTVEHKVAIAERLIEDLTGNWGIHESDILIDTLTFTICTGQEESRKDGIATIEA
IRELKRRHPDVQTTLGLSNISFGLNPAARVVLNSVFLDECVKAGLDSAIVHASKILPIAR
LEEEQVKVAHDLIYDRREEGYDPLQKLMELFEGVNMKSMKAGKAEELLALPLDERLQRRI
IDGEKNGLEDDLTEALETRPALDIVNDTLLEGMKVVGELFGSGQMQLPFVLQSAEVMKTA
VAHLEPHMEKSDSEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVAAIL
DAAAEHRADVIGMSGLLVKSTVIMKENLEELNQRKMAADFPVILGGAALTRAYVEQDLHE
IYEGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRVPKKDTPVLEVTEDDGPAR
SDVSVDNPVPTPPFWGTRVVKGIQLKEYASWLDEGALFKGQWGLKEARKGDGPSYEELVE
TEGRPRLRGWLDELHTKNMLEAAVVHGYFPCVSKGDDLIILDDQGNERTRFSFPRQRRGR
RLCLADFFRPEESGETDVVGLQVVTVGSKIGEATADLFAADSYRDYLELHGLSVQLAEAL
AEYWHARVRAELGFGGEDPAAVEDMFDLKYRGARFSLGYGACPNLEDRAKIAELLEPERI
GVELSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3519 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgttgccaaccccctcgtccggtctccacgacgggacccgagtcgaagccctt
cgcgaagccctcgccacccgcgtcgtggtggccgacggagcgatgggcacgatgctccag
gcacaggaccccactcttgaggacttccagaacctcgagggctgtaacgagatcctgaac
gtgacccgcccggacatcgtgcgctcggtccacgaggagtacttcgcggtcggtgtcgac
tgtgtcgagacgaacacgttcggcacgaacttcgccgccttgagcgagtacgacatcacc
gagcggaaccacgagctctccgaggcgggcgcgcggatcgcccgcgaggtcgccgacgag
ttcaccgcgaagaccggtcagcagcgctgggtccttggctcgatgggccccggcaccaag
ctgccgaccctgggccacgccccgtacacgacgctgcgtgacgcctaccagatcaacgcc
gagggcatgatcgcgggcggcgccgacgccctcctggtggagacgacccaggacctgctg
cagaccaagtccgcgatcctgggcgcccgccgcgccctggaggccaccggcacgagcctc
ccgctgatctgctcggtcaccgtcgagaccaccggcacgatgctgctcggctccgagatc
ggcgcggccctgaccgcgctggagccgctgggcatcgacatgatcggcctgaactgcgcc
acgggcccggccgagatgagcgagcacctgcgctatctggcccgccactcgcgcgtcccg
atctcctgcatgcccaacgcgggcctgccggtcctgggcaagaacggcgcccactacccg
ctgaccgaggccgagctcgccgacgcccaggagaccttcgtacgcgagtacggcctctcc
ctggtcggcggctgctgcggcacgacccccgagcacctgcgccaggtcgtggagcgggtg
cgcggcgtggagacggtgcgccgtgagccgcaccccgagcccggcgcggcctcgctctac
cagaccgtgcccttccgccaggacaccgcctacatggcgatcggcgagcgcacgaacgcc
aacggctcgaagaagttccgcgaggcgatgctggacgcccgctgggacgactgtgtggag
atggcccgtgaccagatccgcgagggcgcccacatgctcgacctgtgcgtcgactacgtg
ggccgtgacggcgtcgcggacatggccgagctcgccggccggttcgccaccgcctccacg
ctgcccatcgtcctggactcgaccgaactgccggtcatccaggccgggttggagaagctg
ggcggccgcgcggtcatcaactccgtcaactacgaggacggggacggccccgagtcccgc
ttcgcgaaggtcaccgcgctcgccaaggagcacggcgccgcgctgatcgcgctgaccatc
gacgaggagggccaggcccgcaccgtcgagcacaaggtcgccatcgccgagcgcctcatc
gaggacctgaccggcaactggggcatccacgagtcggacatcctcatcgacaccctgacc
ttcaccatctgcaccggtcaggaggagtcccgcaaggacggcatcgccaccatcgaggcg
atccgcgagctcaagcgccgccacccggacgtgcagaccaccctgggcctgtcgaacatc
tccttcggcctcaacccggccgcccgtgtcgtgttgaactccgtcttcctggacgagtgc
gtcaaggcgggcctggactcggccatcgtgcacgcctccaagatcctgcccatcgcgcgg
ctggaggaggagcaggtcaaggtcgcccacgacctgatctacgaccgccgcgaagagggc
tatgaccccttgcagaagctcatggagctcttcgagggcgtcaacatgaagtcgatgaag
gcgggcaaggccgaggagctccttgccctgccgctggacgagcggctccagcgccgcatc
atcgacggcgagaagaacggcctggaggacgacctcaccgaggccctggagacccgcccg
gcgctcgacatcgtcaacgacaccctcctggagggcatgaaggtcgtgggcgagctgttc
ggctcgggccagatgcagctgcccttcgtgctgcagtccgcggaggtcatgaagaccgcg
gtcgcgcacctggagccgcacatggagaagtcggactccgagggcaagggcaccatcgtc
ctggccaccgtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcttg
tccaacaacggctacaacgtggtcaacctcggcatcaagcagcccgtagcggcgatcctg
gacgccgcggccgagcaccgcgccgacgtgatcggcatgtcgggtctcctggtgaagtcg
accgtgatcatgaaggagaacctggaggagctcaaccagcgcaagatggcggccgacttc
ccggtgatcctcggcggcgcggcgctgacccgtgcgtacgtcgagcaggacctgcacgag
atctacgagggcgaggtccgctacgcccgcgacgcgttcgagggcctgcgcctgatggac
gccctcatcgcggtcaagcgcggcgtccccggcgccaccctgcccgagctgaagcagcgc
cgcgtgcccaagaaggacacccccgtcctggaggtcaccgaggacgacgggcccgcccgc
tcggacgtctcggtcgacaatcccgtccccaccccgccgttctggggcacccgcgtggtc
aagggcatccagctcaaggagtacgcctcctggctggacgagggcgccctgttcaagggc
cagtggggcctcaaggaggcccgcaagggtgacggaccctcgtacgaggagctcgtcgag
accgagggccggccccgccttcgaggctggctggacgagctgcacaccaagaacatgctg
gaggcggccgttgtgcacggctacttcccctgcgtctccaagggtgacgacctgatcatc
ctggacgaccagggcaacgagcgcacccgcttctccttcccgcgccagcgccgcggccgg
cgcctgtgccttgcggacttcttccgcccggaggagtccggcgagaccgacgtggtcggc
ctgcaggtcgtcaccgtcggctcgaagatcggcgaggccaccgccgatcttttcgccgcc
gactcctaccgcgactacctcgaactgcacggcctgtccgtgcagttggccgaggcactc
gcggagtactggcacgcgcgcgtgcgcgccgaactcggcttcggcggcgaggaccccgcc
gccgtcgaggacatgttcgacctcaagtaccgcggcgcgcgcttctcgctcggctacggc
gcctgcccgaacctggaggaccgcgccaagatcgccgagctcctggagccggagcggatc
ggtgtggagctgtccgaggagttccagctccacccggagcagtccacggacgcgatcgtc
atccaccaccccgaggcgaaatacttcaacgcgcgttaa
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