Shigella dysenteriae Sd197: SDY_4322
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Entry
SDY_4322 CDS
T00306
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sdy
Shigella dysenteriae Sd197
Pathway
sdy00270
Cysteine and methionine metabolism
sdy00450
Selenocompound metabolism
sdy00670
One carbon pool by folate
sdy01100
Metabolic pathways
sdy01110
Biosynthesis of secondary metabolites
sdy01230
Biosynthesis of amino acids
sdy04980
Cobalamin transport and metabolism
sdy04981
Folate transport and metabolism
Module
sdy_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sdy00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SDY_4322 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SDY_4322 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SDY_4322 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SDY_4322 (metH)
04980 Cobalamin transport and metabolism
SDY_4322 (metH)
Enzymes [BR:
sdy01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SDY_4322 (metH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ABB64216
ShiBASE_China:
SDY4322
UniProt:
Q328N9
LinkDB
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Position
complement(4048807..4052505)
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AA seq
1232 aa
AA seq
DB search
MSSKVEQLRAQLNEHILVLDSGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVNTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSQIAECYVTAHPNAGLPNAFGEYALDADTMAKQIREWAQ
AGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGEDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDDTANAQQAEWRAWEVN
KRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVVVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYP
ACPEHTEKATIWELLEVEKHTGMKLTESFAMWPSASVSGWYFSHPDSKYYAVAQIQRDQV
EDYARRKGMSVSDVERWLAPNLGYGDAANLLI
NT seq
3699 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagtggaacaactgcgtgcgcagttaaatgaacatattctggtgctggac
agcggtatgggcaccatgatccagagctatcgactgaacgaagccgattttcgtggtgaa
cgctttgccgactggccatgcgacctcaaaggcaataacgatctgctggtgctcagtaaa
ccggaagtgatcgccgctatccacaacgcctactttgaagcgggcgcggatatcatcgaa
accaacaccttcaactccacgaccattgcgatggcggattaccagatggaatccctgtcg
gcggaaatcaactttgcggcggcgaaactggcgcgcgcttgtgctgacgagtggaccgcc
cgcacgccggagaaaccgcgctacgttgccggcgttctcggcccaaccaaccgcacggcg
tccatttctccggacgtgaacgatccggcattccgcaacatcacttttgaccagctggtg
gcggcctatcgcgaatccaccaaagcattagtggaaggtggtgcggatctgattctgatt
gaaaccgttttcgacacccttaacgccaaagcggcggtctttgcggtgaacacggagttt
gaagcgctgggcgttgagctgccgattatgatctccggcaccatcaccgacgcctccggg
cgcacgctctccgggcagaccaccgaagcgttttataactctctgcgccacgccgaagcg
ctgactttcggcctgaactgtgcgctggggccagatgaactgcgccagtacgtgcaggag
ctgtcacagattgcggaatgctacgtcaccgcgcacccgaacgccggactgcccaacgcc
tttggtgagtacgctctcgacgccgacacgatggcaaaacagatacgtgaatgggcgcaa
gcgggctttctcaatatcgtcggcggctgctgtggcaccacgccacaacatattgcagca
atgagtcgtgcagtagaaggattagcgccgcgcaaactgcctgaaattcccgtagcctgc
cgtttgtccggcctggagccgctgaacattggcgaagatagcctgtttgtgaacgtgggt
gaacgcaccaacgtcaccggttcagctaagttcaagcgcctgatcaaagaagagaaatac
agcgaggcgctggatgtagcgcgtcagcaggtggaaaacggtgcgcagattatcgatatc
aacatggatgaagggatgctcgatgccgaagcggcgatggtgcgttttctcaatctgatc
gccggtgaaccggatatcgctcgcgtgccgattatgatcgactcctcaaaatgggaggtc
atcgaaaaggggctgaagtgtattcagggcaaaggcattgttaactctatctcaatgaaa
gagggcgtcgacgcctttatccatcatgcgaaactgttgcgtcgttacggtgcagcggtg
gtggtaatggcctttgacgaacagggacaggccgatacccgcgcacggaaaatcgagatt
tgccgtcgagcgtacaaaatcctcaccgaagaggttggcttcccgccagaagatatcatc
ttcgacccgaacattttcgcggtcgccaccggcattgaagagcacaacaactatgcgcag
gactttatcggcgcgtgtgaagacatcaaacgcgaactgccgcacgcgctgatttccggc
ggcgtctccaacgtctcgttctcgttccgtggtaacgatccggtgcgcgaagctattcac
gcggtgttcctctactacgctattcgcaatggcatggatatggggatcgtcaacgccggg
caactggcgatttacgacgacctgcccgctgaactgcgcgacgcggtggaagatgtgatt
cttaaccgtcgcgacgatggcaccgagcgtttactggagcttgccgagaaatatcgcggc
agcaaaaccgacgacaccgctaacgcccagcaggcggagtggcgtgcgtgggaagtgaat
aaacgtctggagtactcgttggtcaaaggcattaccgagtttatcgagcaggataccgaa
gaagcacgccagcaggctacgcgcccgattgaagtgattgaaggcccgctaatggacggc
atgaacgtggtcggcgatctgttcggcgaagggaaaatgttcctgccacaggtggtcaaa
tcggcgcgtgtgatgaagcaggcggtggcctacctcgaaccgtttattgaagccagcaaa
gagcagggcaaaaccaacggcaagatggtgatcgccaccgtgaagggcgacgtccacgac
atcggtaaaaatatcgttggtgtggtgctgcaatgtaacaactacgaaattgtcgatctc
ggcgttatggtgcctgcggaaaaaattctccgtaccgctaaagaagtgaatgctgatctg
attggactttcggggcttatcacgccgtcgctggacgagatggttaacgtggcgaaagag
atggagcgtcagggcttcaccattccgttactgatcggtggcgcgacgacctcaaaagcg
cacacggcggtgaaaattgagcagaactacagcggcccgacggtgtatgtgcagaatgcc
tcgcgcaccgttgtcgtggtggcggcgctgctttccgatactcagcgcgatgattttgtc
gctcgtacccgcaaggagtacgaaaccgtgcgtattcagcacgggcgcaagaaaccacgc
acaccaccggtcacgctggaagcggcgcgcgataacgatttcgcttttgactggcaggct
tacacgccgccggtggcgcaccgtctcggcgtgcaggaagtcgaagccagcatcgaaacg
ctgcgtaattacatcgactggacaccgttctttatgacctggtcgctggccgggaagtat
ccgcgcattctggaagatgaagttgtgggcgttgaggcgcagcggctgtttaaagacgcc
aacgacatgctggataaattaagcgccgagaaaacgctgaatccgcgtggcgtggtgggc
ctgttcccggcaaaccgtgtgggcgatgacattgaaatctaccgtgacgaaacgcgcacc
catgtgatcaacgtcagccaccacctgcgtcaacagaccgaaaaaacgggattcgctaac
tactgtctcgctgacttcgttgcgccgaagctttctggtaaagcagattacatcggcgca
tttgccgtgactggcgggctggaagaagacgcactggctgatgcctttgaagcacagcac
gatgattacaacaaaatcatggtgaaagcgcttgccgaccgtttagccgaagcctttgcg
gagtatctccatgagcgtgtgcgtaaagtctactggggctatgcgccgaacgagaacctc
agcaacgaagaactgatccgcgaaaactaccagggcatccgtccggcaccgggctatccg
gcctgcccggaacatacggaaaaagccaccatctgggagctgctggaagtggaaaaacat
actggcatgaaactcacagaatctttcgccatgtggcctagtgcatcggtttcgggttgg
tatttcagtcatccggacagcaagtactacgcggtggcgcaaattcagcgcgatcaggtt
gaagactatgcccgccgtaaaggtatgagcgtctccgatgttgagcgctggctggcaccg
aatctggggtatggtgatgctgccaacttactgatttag
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