KEGG   Shigella dysenteriae Sd197: SDY_4322
Entry
SDY_4322          CDS       T00306                                 
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
sdy  Shigella dysenteriae Sd197
Pathway
sdy00270  Cysteine and methionine metabolism
sdy00450  Selenocompound metabolism
sdy00670  One carbon pool by folate
sdy01100  Metabolic pathways
sdy01110  Biosynthesis of secondary metabolites
sdy01230  Biosynthesis of amino acids
sdy04980  Cobalamin transport and metabolism
sdy04981  Folate transport and metabolism
Module
sdy_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:sdy00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    SDY_4322 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    SDY_4322 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SDY_4322 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    SDY_4322 (metH)
   04980 Cobalamin transport and metabolism
    SDY_4322 (metH)
Enzymes [BR:sdy01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     SDY_4322 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ABB64216
ShiBASE_China: SDY4322
UniProt: Q328N9
LinkDB
Position
complement(4048807..4052505)
AA seq 1232 aa
MSSKVEQLRAQLNEHILVLDSGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVNTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSQIAECYVTAHPNAGLPNAFGEYALDADTMAKQIREWAQ
AGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGEDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDDTANAQQAEWRAWEVN
KRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVVVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRT
HVINVSHHLRQQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYP
ACPEHTEKATIWELLEVEKHTGMKLTESFAMWPSASVSGWYFSHPDSKYYAVAQIQRDQV
EDYARRKGMSVSDVERWLAPNLGYGDAANLLI
NT seq 3699 nt   +upstreamnt  +downstreamnt
gtgagcagcaaagtggaacaactgcgtgcgcagttaaatgaacatattctggtgctggac
agcggtatgggcaccatgatccagagctatcgactgaacgaagccgattttcgtggtgaa
cgctttgccgactggccatgcgacctcaaaggcaataacgatctgctggtgctcagtaaa
ccggaagtgatcgccgctatccacaacgcctactttgaagcgggcgcggatatcatcgaa
accaacaccttcaactccacgaccattgcgatggcggattaccagatggaatccctgtcg
gcggaaatcaactttgcggcggcgaaactggcgcgcgcttgtgctgacgagtggaccgcc
cgcacgccggagaaaccgcgctacgttgccggcgttctcggcccaaccaaccgcacggcg
tccatttctccggacgtgaacgatccggcattccgcaacatcacttttgaccagctggtg
gcggcctatcgcgaatccaccaaagcattagtggaaggtggtgcggatctgattctgatt
gaaaccgttttcgacacccttaacgccaaagcggcggtctttgcggtgaacacggagttt
gaagcgctgggcgttgagctgccgattatgatctccggcaccatcaccgacgcctccggg
cgcacgctctccgggcagaccaccgaagcgttttataactctctgcgccacgccgaagcg
ctgactttcggcctgaactgtgcgctggggccagatgaactgcgccagtacgtgcaggag
ctgtcacagattgcggaatgctacgtcaccgcgcacccgaacgccggactgcccaacgcc
tttggtgagtacgctctcgacgccgacacgatggcaaaacagatacgtgaatgggcgcaa
gcgggctttctcaatatcgtcggcggctgctgtggcaccacgccacaacatattgcagca
atgagtcgtgcagtagaaggattagcgccgcgcaaactgcctgaaattcccgtagcctgc
cgtttgtccggcctggagccgctgaacattggcgaagatagcctgtttgtgaacgtgggt
gaacgcaccaacgtcaccggttcagctaagttcaagcgcctgatcaaagaagagaaatac
agcgaggcgctggatgtagcgcgtcagcaggtggaaaacggtgcgcagattatcgatatc
aacatggatgaagggatgctcgatgccgaagcggcgatggtgcgttttctcaatctgatc
gccggtgaaccggatatcgctcgcgtgccgattatgatcgactcctcaaaatgggaggtc
atcgaaaaggggctgaagtgtattcagggcaaaggcattgttaactctatctcaatgaaa
gagggcgtcgacgcctttatccatcatgcgaaactgttgcgtcgttacggtgcagcggtg
gtggtaatggcctttgacgaacagggacaggccgatacccgcgcacggaaaatcgagatt
tgccgtcgagcgtacaaaatcctcaccgaagaggttggcttcccgccagaagatatcatc
ttcgacccgaacattttcgcggtcgccaccggcattgaagagcacaacaactatgcgcag
gactttatcggcgcgtgtgaagacatcaaacgcgaactgccgcacgcgctgatttccggc
ggcgtctccaacgtctcgttctcgttccgtggtaacgatccggtgcgcgaagctattcac
gcggtgttcctctactacgctattcgcaatggcatggatatggggatcgtcaacgccggg
caactggcgatttacgacgacctgcccgctgaactgcgcgacgcggtggaagatgtgatt
cttaaccgtcgcgacgatggcaccgagcgtttactggagcttgccgagaaatatcgcggc
agcaaaaccgacgacaccgctaacgcccagcaggcggagtggcgtgcgtgggaagtgaat
aaacgtctggagtactcgttggtcaaaggcattaccgagtttatcgagcaggataccgaa
gaagcacgccagcaggctacgcgcccgattgaagtgattgaaggcccgctaatggacggc
atgaacgtggtcggcgatctgttcggcgaagggaaaatgttcctgccacaggtggtcaaa
tcggcgcgtgtgatgaagcaggcggtggcctacctcgaaccgtttattgaagccagcaaa
gagcagggcaaaaccaacggcaagatggtgatcgccaccgtgaagggcgacgtccacgac
atcggtaaaaatatcgttggtgtggtgctgcaatgtaacaactacgaaattgtcgatctc
ggcgttatggtgcctgcggaaaaaattctccgtaccgctaaagaagtgaatgctgatctg
attggactttcggggcttatcacgccgtcgctggacgagatggttaacgtggcgaaagag
atggagcgtcagggcttcaccattccgttactgatcggtggcgcgacgacctcaaaagcg
cacacggcggtgaaaattgagcagaactacagcggcccgacggtgtatgtgcagaatgcc
tcgcgcaccgttgtcgtggtggcggcgctgctttccgatactcagcgcgatgattttgtc
gctcgtacccgcaaggagtacgaaaccgtgcgtattcagcacgggcgcaagaaaccacgc
acaccaccggtcacgctggaagcggcgcgcgataacgatttcgcttttgactggcaggct
tacacgccgccggtggcgcaccgtctcggcgtgcaggaagtcgaagccagcatcgaaacg
ctgcgtaattacatcgactggacaccgttctttatgacctggtcgctggccgggaagtat
ccgcgcattctggaagatgaagttgtgggcgttgaggcgcagcggctgtttaaagacgcc
aacgacatgctggataaattaagcgccgagaaaacgctgaatccgcgtggcgtggtgggc
ctgttcccggcaaaccgtgtgggcgatgacattgaaatctaccgtgacgaaacgcgcacc
catgtgatcaacgtcagccaccacctgcgtcaacagaccgaaaaaacgggattcgctaac
tactgtctcgctgacttcgttgcgccgaagctttctggtaaagcagattacatcggcgca
tttgccgtgactggcgggctggaagaagacgcactggctgatgcctttgaagcacagcac
gatgattacaacaaaatcatggtgaaagcgcttgccgaccgtttagccgaagcctttgcg
gagtatctccatgagcgtgtgcgtaaagtctactggggctatgcgccgaacgagaacctc
agcaacgaagaactgatccgcgaaaactaccagggcatccgtccggcaccgggctatccg
gcctgcccggaacatacggaaaaagccaccatctgggagctgctggaagtggaaaaacat
actggcatgaaactcacagaatctttcgccatgtggcctagtgcatcggtttcgggttgg
tatttcagtcatccggacagcaagtactacgcggtggcgcaaattcagcgcgatcaggtt
gaagactatgcccgccgtaaaggtatgagcgtctccgatgttgagcgctggctggcaccg
aatctggggtatggtgatgctgccaacttactgatttag

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