Salmonella enterica subsp. enterica serovar Choleraesuis: SCH_4067
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Entry
SCH_4067 CDS
T00240
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase, repressor of metE and metF
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sec
Salmonella enterica subsp. enterica serovar Choleraesuis
Pathway
sec00270
Cysteine and methionine metabolism
sec00450
Selenocompound metabolism
sec00670
One carbon pool by folate
sec01100
Metabolic pathways
sec01110
Biosynthesis of secondary metabolites
sec01230
Biosynthesis of amino acids
sec04981
Folate transport and metabolism
Module
sec_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sec00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SCH_4067 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SCH_4067 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SCH_4067 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SCH_4067 (metH)
04980 Cobalamin transport and metabolism
SCH_4067 (metH)
Enzymes [BR:
sec01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SCH_4067 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AAX67973
UniProt:
Q57H39
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All DBs
Position
4341607..4345377
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AA seq
1256 aa
AA seq
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MSHVARCSLFRQHALCQYGSLRGALSGASVSSKVEQLRAQLNERILVLDGGMGTMIQSYR
LHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAM
ADYRMESLSAEINYAAAKLARACADEWTVRTPNKPRYVAGVLGPTNRTASISPDVNDPAF
RNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMI
SGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTA
HPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLPPR
QLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQV
EGGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGK
GIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKILTEE
VGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVSFSFRG
NDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERL
LELAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIE
VIEGPLMDGMNVVGDLFGEGKVFLPQVVKSARVMKQAVAYLEPFIEASKEKGSSNGKMVI
ATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSGLITPSL
DEMVNVAKEMERQGFTIPVLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALL
SDTQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVAHRLGV
QEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGIEAQRLFKDANDMLDKLSAEK
LLNPRGVVGLFPANRIGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLADFVAPKL
SGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVY
WGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAM
WPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYDAD
NT seq
3771 nt
NT seq
+upstream
nt +downstream
nt
atgtctcatgttgcccgttgttctcttttccgccagcacgctttgtgccagtatggctcg
ttacgtggagcgttgtcgggagcgagtgtgagcagcaaagttgaacaactgcgtgcgcag
ttaaatgaacgtattctggtgctggacggcggtatgggcaccatgatccagagctatcgt
ctacatgaagaagatttccgcggggagcgctttgccgactggccctgcgacctgaaaggc
aacaatgacctgctggtcctcagcaagccggaggtgatcgccgctatccacaacgcctac
tttgaggcgggcgcggatatcatcgaaaccaacacctttaactcgacaaccattgcgatg
gcggattaccggatggaatccctgtcggcggaaattaactatgcggcggccaaactggcg
cgcgcctgcgccgatgaatggacggtgcgtacgccgaacaaaccgcgctacgtcgcgggt
gtgctcggcccaaccaaccgcacggcctccatttcgccggacgtcaacgacccggcgttt
cgtaatatcaccttcgatcagctggtggcggcctaccgtgaatccaccaaagcgctggtg
gaaggcggggcggacctgatcctgattgaaaccgtcttcgacaccctcaacgccaaagcg
gcggtgtttgcggtgaaagaagagtttgaagcgctgggcgttgatctgccgatcatgatt
tccggcaccatcaccgacgcctctggccgtacgctttccggccagacgaccgaagccttt
tataactcgctgcgccacgccgaggcgctcacttttggccttaactgcgcgctggggcct
gatgagctgcgccagtacgtccaggaactgtcgcggattgccgaatgctacgtcaccgcg
cacccgaacgccggcctgccgaacgctttcggcgagtacgacctcgacgccgacaccatg
gcgaaacagattcgcgaatgggcggaagcgggcttcctgaatattgttggcggctgctgc
ggcaccacgccggagcatattgcggcgatgagccgcgccgttgccggtttgccgccgcgc
cagctgccggatatcccggtggcctgccgcctttccggcctggagccgctgaatatcggc
gacgatagcctgtttgtcaacgtcggcgaacgtactaacgtcaccggctcggccaaattt
aagcgcttgatcaaagaagagaaatacagcgaagcgctggatgtcgctcgtcagcaggta
gaaggcggcgcgcagattattgatatcaatatggatgaggggatgctcgacgccgaagcg
gcgatggtgcgtttcctcagcctgattgccggtgagccggacattgcccgtgtaccaatc
atgattgactcctccaaatgggaggttatcgaaaaagggctgaagtgcattcagggtaaa
ggcatcgtcaactctatttcgatgaaagagggcgtggaagcctttatccatcatgcgaag
ttgctacgtcgctatggcgccgcagtggtggtgatggcttttgatgagcaggggcaggcc
gatacccgcgagcgtaaaatcgaaatttgccgccgagcctacaaaattctcaccgaagag
gtgggcttcccgccggaagacatcattttcgacccgaatatctttgccgtcgccaccggt
attgaagagcacaacaactacgcgcaggactttatcggcgcctgtgaggacatcaaacgc
gagctgccgcatgcgctgatctccggcggcgtgtctaacgtgtccttctcgttccgcggc
aacgacccggtacgtgaggctatccacgcggtattcctctactacgccatccgcaatggc
atggacatgggcatcgtcaacgccgggcaactggcgatttatgacgacctgcctgccgaa
ctgcgcgatgcggttgaagatgtcattcttaaccgtcgcgatgacggcaccgagcgtttg
ctggaactggccgagaaataccgcggcagcaaaaccgacgaagctgccaacgcacagcag
gcggaatggcgtagctgggacgtgaaaaagcgtctcgaatactcgctggtgaaaggcatt
accgaatttatcgaacaggataccgaagaagcccgccagcaggccgcccgcccgattgag
gtgatcgaaggcccgctgatggacggcatgaacgtggtcggcgacctgttcggcgaaggg
aaagtgttcctgccgcaggtggtgaaatccgctcgcgtgatgaaacaagcggtggcctac
ctggagccgtttattgaagccagcaaagaaaaaggctccagcaacggcaagatggtgatt
gccaccgtgaagggcgatgtgcacgacattggcaagaacattgttggcgtggtgctgcaa
tgcaacaactacgaaatcgtcgatcttggcgtgatggtgcctgcggagaaaatcctcaga
acggcgcgtgaagtgaatgccgatctgattggcctttccgggctgattaccccgtcgctg
gacgaaatggtcaacgtggcgaaagagatggagcgtcagggctttactatcccggtactg
atcggcggcgcaaccacttcgaaagcgcatacggcggtgaaaatcgagcagaactacagc
ggtccgacggtctacgtgcagaatgcttcgcgtaccgtgggcgtggtggcggcgctactc
tccgacacccagcgtgatgactttgtcgcccgtacccgcaaagagtacgaaaccgtgcgt
attcagcacgcccgcaaaaaaccgcgcacgccgccggtcacgctggaagcggcgcgcgat
aacgatctggcgttcgattgggaacgctacaccccgccggtagcccaccgtctgggcgtg
caggaggtggaagccagtatcgaaactctgcgcaactacatcgactggacgccgttcttt
atgacctggtcgctggccggcaaatacccgcgcattctggaagatgaggtggtgggcatt
gaggcgcagcgtctgtttaaagacgccaatgatatgctggataaactgagcgccgagaaa
ctgttgaatccgcgtggcgtggtgggcctgttcccggcgaaccgcatcggcgatgacatc
gaaatctatcgcgacgaaacccgtactcatgttctgacggtcagccaccacctgcgccag
cagaccgagaaagtcggttttgccaactactgtctggcggattttgttgcgccgaaactg
agcggcaaagcggattacatcggtgctttcgcggtgaccggcggtctggaggaggatgcg
ctggcggacgccttcgaagcgcaacacgacgactataacaagatcatggtgaaagcgatt
gccgaccgtctggcggaagcgttcgcggaatatctgcatgagcgtgtacgtaaggtttac
tggggatatgcgccgaacgagagcctgagtaacgacgaattaatccgcgaaaactaccag
gggattcgcccggcgccgggttatcctgcctgcccggaacataccgaaaaaggcactatc
tggcagctactggatgtcgaaaaacacaccgggatgaagctcaccgaatctttcgccatg
tggccaggcgcgtcggtctccggctggtacttcagccatcctgagagcaaatactttgcg
gtagcgcagatccaacgcgatcaggtgacagattatgctttccgtaaaggaatgagcgtt
gaggatgttgagcggtggctcgcgccgaacctgggttacgatgcggactga
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