Salmonella enterica subsp. enterica serovar Cubana: CFSAN002050_03345
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Entry
CFSAN002050_03345 CDS
T02734
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
seec
Salmonella enterica subsp. enterica serovar Cubana
Pathway
seec00260
Glycine, serine and threonine metabolism
seec00261
Monobactam biosynthesis
seec00270
Cysteine and methionine metabolism
seec00300
Lysine biosynthesis
seec01100
Metabolic pathways
seec01110
Biosynthesis of secondary metabolites
seec01120
Microbial metabolism in diverse environments
seec01230
Biosynthesis of amino acids
Module
seec_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
seec_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
seec_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
seec00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
CFSAN002050_03345 (metL)
00270 Cysteine and methionine metabolism
CFSAN002050_03345 (metL)
00300 Lysine biosynthesis
CFSAN002050_03345 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
CFSAN002050_03345 (metL)
Enzymes [BR:
seec01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
CFSAN002050_03345 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
CFSAN002050_03345 (metL)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
HTH_11
JASON_N
Motif
Other DBs
NCBI-ProteinID:
AGQ71537
LinkDB
All DBs
Position
370050..372482
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AA seq
810 aa
AA seq
DB search
MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVLQTLRRYQCDLISGLLPADAADDLTSAFISDLERLAALLDGGVTDA
VYAEIVGHGEIWSARLMSAVLNQQGLDAAWLDARAFLRAERAAQPQVDEGLSYPLLQQLL
AQHPGKRLVVTGFISRNHDGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDICLIEFQVPASQDFRLAHKELDHILKRAQARPLAVGVHRDRQLL
QFCYTAEVADSVLKLLDDVGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRTGPTESLIQGLHQSVFRAEKRIGLMLFGKGNIGSRWLELFARE
QSTLSARTGFEFVLAGVVDSRRSLLNYEGLDASRALAFFDDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASEQLADQYLDFASHGFHVISANKLAGASASDKYRQIHDAFEKTGRYWLYN
ATVGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYDIEPDQVRVESLVPAHCEEGSIDHFFENGDALNE
QMVQRLEAARELGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgattgcgcaggcaggggcgaaaggtcgtcaactgcataaatttggcggcagt
agtctggcggatgtgaagtgttacctgcgtgtcgcaggcattatggcggagtattcgcag
cctgacgatatgatggtagtgtccgccgcaggcagtaccaccaaccagttgattagctgg
ctcaagttaagccagaccgatcgcctttctgcgcatcaggtattacagacgttacgccgc
taccagtgcgatctgattagcgggctgcttcccgccgacgcggcagatgacttaaccagc
gcttttatcagcgatctggaacgtcttgccgccttgctcgacggcggcgtaacggatgcc
gtctatgccgagattgtcggacacggcgaaatttggtcggcgagattgatgtccgccgtc
ctgaatcagcaggggctggatgccgcctggctggacgcgcgcgcatttttacgcgccgaa
cgcgccgcacagccgcaggttgatgaagggctatcttatcctttattgcaacagctactg
gcgcagcatcctggcaaacgtctggtcgtgaccgggtttatcagccgcaatcacgacggc
gaaacggtcctgttaggccggaacggttccgactattccgccacgcaaatcggcgcgctg
gcgggcgtttcccgcgtgaccatctggagcgatgtcgcgggcgtttatagtgccgacccg
cgcaaagtgaaagatgcctgcctgctgccgttgctgcgtctggacgaagccagcgagctg
gcgcgtctggcggcgcctgttctgcacgcccgcacgctacagccagtgtccggcagcgat
atcgatttgcagttgcgctgtagctacacgccggatcaagggtcaacccgaattgaacga
gtgctggcttccgggacgggcgcgcgtatcgtgaccagtcacgatgatatctgtctgatt
gagtttcaggtgcctgccagccaggatttcaggctggcgcacaaagagctcgaccacatt
ttaaaacgggcgcaggcgcgtccgctggcagtgggcgtgcatcgcgatcgccagctattg
cagttctgctataccgccgaggtagcggatagtgtactgaaactcctcgacgatgtcggg
ctgccgggcgaattgcgcctgcgacaggggctggcgctggtggcgatggtcggtgcgggc
gttactcgcaatccgctacactgccatcgcttctggcagcagcttaaaggtcagccagtg
gaatttacctggcagtcggaggagggcatcagtctggtggcggtgctgcgtaccggccca
actgagagcctgattcaggggctgcatcagtcggttttccgcgccgaaaaacgcattggc
ctgatgctgttcggtaaggggaacatcggctcccgttggctggaactgtttgcccgtgaa
caaagcacgctttccgcgcgtactggttttgaatttgtgctggcgggcgtggtggatagc
cgccgcagcctgctgaattatgaagggctggacgccagccgcgcgctggcattctttgat
gatgaagccgttgagcaggacgaagagtcgctattcctgtggatgcgtgcgcatccgtat
gatgatttagtggtgctggatgtgacagcaagcgagcaactggccgatcagtatctggat
ttcgccagccacggttttcatgtgattagcgccaataaactggcgggcgcaagcgccagc
gataagtatcgccagattcatgacgcgtttgaaaaaaccgggcgttactggctgtataac
gccaccgtgggcgcgggattgccgatcaaccacacggtgcgggatctgattgacagcggc
gatacgattctctcgatcagcgggatcttctccgggacgctatcctggctgttcctgcaa
tttgacggtacggtgccgtttaccgatctggtggatcaggcctggcagcaggggctgacc
gaacccgatccgcgcgtcgatctttccggaaaagatgtcatgcgtaagctggtgattctg
gcgcgcgaggcgggatacgacatcgagccggatcaggtgcgtgtagaatcgttggtgccg
gcgcactgtgaagaagggtctatcgatcactttttcgaaaacggcgacgcgctgaatgaa
cagatggtgcagcgtctggaggcagcccgcgaactggggctggtgttgcgttacgtggcg
cgtttcgacgccaatggcaaagcgcgcgtcggcgttgaagcggtgcgtccggaacatccg
ctggcggcgctgctgccgtgcgataatgtctttgctattgaaagccgctggtatcgcgat
aacccgctggtgatccgtgggccgggcgcgggccgcgatgtgaccgccggggcgattcag
tcggatatcaaccgcctggcgcagttgctgtaa
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