Salmonella enterica subsp. enterica serovar Cubana: CFSAN002050_03760
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Entry
CFSAN002050_03760 CDS
T02734
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
seec
Salmonella enterica subsp. enterica serovar Cubana
Pathway
seec00270
Cysteine and methionine metabolism
seec00450
Selenocompound metabolism
seec00670
One carbon pool by folate
seec01100
Metabolic pathways
seec01110
Biosynthesis of secondary metabolites
seec01230
Biosynthesis of amino acids
seec04981
Folate transport and metabolism
Module
seec_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
seec00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CFSAN002050_03760 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
CFSAN002050_03760 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CFSAN002050_03760 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
CFSAN002050_03760 (metH)
04980 Cobalamin transport and metabolism
CFSAN002050_03760 (metH)
Enzymes [BR:
seec01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
CFSAN002050_03760 (metH)
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AGQ71600
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All DBs
Position
467545..471228
Genome browser
AA seq
1227 aa
AA seq
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MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA
RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGVDLILI
ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQASRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
TDYAFRKGMSVEDVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcactatgatccagagctatcgtctacatgaagaagatttccgcggggag
cgctttgccgactggccctgcgacctgaaaggcaacaatgacctgctggtactcagcaag
ccggaggtgatcgccgctatccacaacgcctactttgaggctggcgcggatatcatcgaa
accaacacctttaactcgacaaccattgcgatggcggattaccggatggaatccctgtcg
gcggaaattaactatgcggcggccaaactggctcgcgcctgcgccgatgaatggacggcg
cgaacaccagaaaaaccacgctttgttgcgggtgtgctcggcccaaccaaccgcacggcc
tccatttcgccggacgtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtg
gcggcctaccgtgaatccactaaagcgctggtggaaggtggcgtagatctgattctgatt
gagaccgtctttgacaccctgaatgcgaaagcggcggtgtttgcggtgaaagaagagttt
gaagcgctgggcgttgacctgccgatcatgatttccggcaccatcaccgacgcctctggc
cgtacgctttccggccagactaccgaagccttttataactcgctgcgccacgccgaggcg
ctcacttttggccttaactgcgcgctggggccagatgaactgcgccagtacgtccaggaa
ctgtcgcggattgccgaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgct
ttcggcgagtacgacctcgacgccgacaccatggcgaaacagattcgcgaatgggcggaa
gcgggcttcctgaatatcgttggcggctgctgtggcactacgccggagcatatcgccgcc
atgagccgcgccgttgccggtttgccgccgcgccagctgccggatatcccggtcgcctgc
cgcctttccggcctggagccgctgaacattggcgacgatagcctgtttgtcaacgtcggc
gagcgtactaacgtcaccggctcggccaaatttaaacggctgatcaaagaagaaaaatac
agcgaagcgctggatgtcgcccgtcagcaggtagaaagcggcgcgcagattattgatatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatt
gccggtgagccggacattgcccgtgtaccaatcatgatcgactcctccaaatgggaagtt
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaa
gagggcgtggaagcctttattcatcatgcgaagttgctacgtcgctacggcgcggcagtg
gtggtgatggcctttgatgagcaggggcaggccgatacccgcgcgcgtaaaatcgaaatt
tgccgccgagcctacaaaattctcaccgaagaggtgggtttcccgccggaagacatcatc
ttcgacccgaatatcttcgccgtcgccaccggtattgaagagcacaacaactacgcgcag
gactttatcggcgcttgtgaagacatcaaacgcgagctgccgcacgcgctgatctccggc
ggcgtctctaacgtgtccttctcgttccgcggcaacgacccggtacgtgaggctatccac
gcggtattcctctactacgccatccgcaacggcatggacatgggcatcgtcaacgccggg
caactggcgatttatgacgacctgcctgccgaactgcgcgatgcggttgaagatgtcatt
cttaaccgtcgcgatgacggcaccgagcgtttgctggatttggcggagaaatatcgcggc
agtaaaaccgacgaggctgccaacgcccagcaggcggaatggcgtagctgggacgtgaaa
aagcgtctcgaatactcgctggtgaaaggcattaccgaatttatcgaacaggataccgaa
gaagcccgccagcaggcctcccgtccgattgaggtgattgaaggcccgctgatggatggc
atgaacgtggtcggcgacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaa
tccgcccgcgtgatgaaacaagcggtggcttacctggagccgtttattgaagccagcaaa
gaaaaaggctccagcaacggcaagatggtcatcgccaccgtgaagggcgatgtgcacgac
attggcaagaacattgttggcgtggtgctgcaatgcaacaactacgaaatcgtcgatctt
ggcgtgatggtgcctgcggagaaaatcctcagaacggcgcgtgaagtgaatgccgatctg
attggcctttccgggctgattaccccgtcgctggacgaaatggtcaacgtggcaaaagag
atggagcgtcagggcttcaccatcccactgctcattggcggcgcgacaacgtcgaaagcg
cacaccgcggtgaaaattgagcagaactacagcggtccgacggtctacgtgcagaatgct
tcgcgtaccgtgggcgtggtggcggcgctactctccgacacccagcgcgatgactttgtc
gcccgtacccgcaaagagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgt
acgccgccggtcacgctggaagcggcgcgcgataacgatctggcattcgattgggaacgc
tacaccccgccggtagcccaccgtctgggcgtgcaggaggtggaagccagcatcgaaact
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggccggcaaatac
ccgcgcattctggaagatgaggtggtgggcgttgaggcgcagcgtctgtttaaagacgcc
aatgatatgctggataaactgagcgccgagaaactgttgaatccgcgtggcgtggtgggc
ctgttcccggcgaaccgtgtgggtgacgacatcgaaatttatcgcgacgaaacccgtact
catgttctgacggtcagccaccacctgcgccagcagaccgagaaagtcggttttgccaac
tactgtctggcggattttgtcgcgccgaaactgagcggcaaagcggattacatcggtgct
ttcgcggtgaccggcggtctggaggaggatgcgctggcggacgccttcgaagcgcaacac
gacgactacaacaagatcatggtgaaggcgattgccgaccgtctggcggaagcgtttgcc
gagtatctgcatgagcgtgtacgtaaggtttactggggatatgcgccgaacgagagcctg
agtaacgacgaattaatccgcgaaaactaccaggggattcgcccggcgccgggttatcct
gcctgcccggaacataccgaaaaaggcactatctggcagctactggatgtcgaaaaacac
accgggatgaagctcaccgaatctttcgccatgtggcctggcgcgtcggtctccggctgg
tacttcagccatcctgagagcaaatacttcgcggtagcgcagatccaacgcgatcaggtg
acagattatgctttccgtaaaggaatgagcgttgaggacgttgagcggtggctggcgccg
aacctgggttacgatgcggactga
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