Salmonella enterica subsp. enterica serovar Gallinarum/pullorum CDC1983-67: SPUCDC_4181
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Entry
SPUCDC_4181 CDS
T02824
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sega
Salmonella enterica subsp. enterica serovar Gallinarum/pullorum CDC1983-67
Pathway
sega00270
Cysteine and methionine metabolism
sega00450
Selenocompound metabolism
sega00670
One carbon pool by folate
sega01100
Metabolic pathways
sega01110
Biosynthesis of secondary metabolites
sega01230
Biosynthesis of amino acids
sega04981
Folate transport and metabolism
Module
sega_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sega00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SPUCDC_4181 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SPUCDC_4181 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SPUCDC_4181 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SPUCDC_4181 (metH)
04980 Cobalamin transport and metabolism
SPUCDC_4181 (metH)
Enzymes [BR:
sega01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SPUCDC_4181 (metH)
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AGU66919
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Position
4232491..4236174
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AA seq
1227 aa
AA seq
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MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA
RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDNQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQGVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDATRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
TDYAFRKGMSVEDVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcaccatgatccagagctatcgtctacatgaagaagatttccgcggggag
cgctttgccgactggccctgcgacctgaaaggcaacaatgacctgctggtactcagcaag
ccggaggtgatcgccgctatccacaacgcctactttgaggctggcgcggatatcatcgaa
accaacacctttaactcgacaaccattgcgatggcggattaccggatggaatccctgtcg
gcggaaatcaactatgcggcggccaaactggcgcgcgcctgcgccgatgaatggacggcg
cgaacaccagaaaaaccacgttttgttgcgggcgtgcttggtccaactaaccgcacggcc
tccatttcgccggacgtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtg
gcggcctaccgtgaatccaccaaagcgctggtggaaggcggggcggacctgatcctgatt
gaaaccgtctttgacaccctgaatgcgaaagcggcggtgtttgcggtgaaagaagagttt
gaagcgctgggcgttgatctgccgatcatgatttccggcaccatcaccgacgcctctggt
cgtaccctctccggccagacgaccgaagccttttataactcgctgcgccacgccgaggcg
ctcacttttggccttaactgcgcgctggggcctgatgagctgcgccagtacgtccaggaa
ctgtcgcggattgccgaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgct
ttcggcgagtacgacctcgacgccgacaccatggcgaaacagattcgcgaatgggcggaa
gcgggcttcctgaatatcgttggcggctgctgtggcactacgccggagcatatcgccgcc
atgagccgcgccgttgccggtttgctgccgcgccagctgccggatatcccggtcgcctgc
cgcctttccggcctggagccgctgaacattggtgacgatagcctgtttgtgaacgtcggc
gaacgtactaacgtcaccggctcggccaaatttaaacggctgatcaaagaagagaaatac
agcgaagcgctggatgtcgcccgtcagcaggtagaaagcggcgcgcagattattgatatc
aatatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatt
gccggtgagccggacattgcccgtgtaccaatcatgatcgactcctccaaatgggaggtt
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaa
gagggcgtggaagcctttattcatcatgcgaagttgctacgtcgctatggcgccgcagtg
gtggtgatggcctttgatgagcaggggcaggccgatacccgcgcgcgtaaaatcgaaatt
tgccgccgagcctacaaaattctcaccgaagaggtgggtttcccgccggaagacatcatc
ttcgacccgaatatcttcgccgtggcgaccggtattgaagagcacaacaactacgcgcag
gactttatcggcgcttgcgaagacatcaaacgcgagctgccgcacgcgctgatctccggc
ggcgtgtctaacgtgtccttctcgttccgcggcaacgacccggtacgtgaggctatccac
gcggtattcctctactacgccatccgcaatggcatggacatgggcatcgtcaacgccggg
caactggcgatttatgacgacctgcctgccgaactgcgcgatgcagttgaagatgtcatt
cttaaccgtcgcgatgacggcaccgagcgtttgctggatttggcggagaaataccgcggc
agcaaaaccgacgaagctgccaacgcccagcaggcggaatggcgtagctgggacgtgaaa
aagcgtctcgaatactcgctggtgaaaggcatcaccgaatttatcgaacaggataccgaa
gaagcccgtcagcaggccgcccgcccgattgaggtgattgaagggccgttgatggacggc
atgaacgtggtcggcgacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaa
tccgctcgcgtgatgaaacaagcggtggcctacctggagccgtttattgaagccagcaaa
gaaaaaggctccagcaacggcaagatggtgatcgccaccgtgaagggcgatgtgcacgat
attggtaaaaatatcgttggcgtggtgctgcaatgtaacaactacgaaatcgtcgatctt
ggcgtgatggtgccagcggagaaaatcctcagaacggcgcgtgaagtgaatgccgatctg
atcggtctttccgggcttatcaccccgtcgctggacgaaatggtcaacgtggcgaaagag
atggagcgtcagggctttactatcccgctactgatcggcggcgcaaccacttcgaaagcg
catacggcggtgaaaatcgagcagaactacagcggtccgacggtctacgtgcagaatgct
tcgcgtaccgtgggcgtggtggcggcgctactctccgacaaccagcgcgatgactttgtc
gcccgtacccgcaaagagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgt
acgccgccggtcacgctggaagcggcgcgcgataatgatctggcattcgattgggaacgc
tacaccccgccggtagcccaccgtctgggcgtgcagggggtggaagccagcatcgaaact
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggccggcaaatac
ccgcgcattctggaagatgaggtggtgggcgttgaggcgcagcgtctgtttaaagacgcc
aatgatatgctggataaactcagcgccgagaagctgttgaatccgcgtggcgtggtgggc
ctgttcccggctaaccgtgtgggtgacgacatcgaaatctatcgcgacgcaacccgtact
catgttctgacggtcagccaccacctgcgccagcagaccgagaaagtcggttttgccaac
tactgtctggcggattttgtcgcgccgaaactgagcggcaaagcggattacatcggtgct
ttcgcggtgaccggcggtctggaggaggatgcgctggcggacgccttcgaagcgcaacac
gacgactataacaagatcatggtgaaagcgattgccgaccgtctggcggaagcgtttgcc
gagtatctgcatgagcgtgtacgtaaggtttactggggatatgcgccgaacgagagcctg
agtaacgacgaattaatccgcgaaaactaccaggggattcgcccggcgccgggttatcct
gcctgcccggaacataccgaaaaaggcactatctggcagctactggatgtcgaaaaacac
accgggatgaagctcaccgaatctttcgccatgtggcctggcgcgtcggtctccggctgg
tacttcagccatcctgagagcaaatacttcgcggtagcgcagatccaacgcgatcaggtg
acagattatgctttccgtaaaggaatgagcgttgaggacgttgagcggtggctggcgccg
aacctggggtacgatgcggactga
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integrated database retrieval system
