Salmonella enterica subsp. enterica serovar Typhimurium T000240: STMDT12_C42490
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Entry
STMDT12_C42490 CDS
T01742
Symbol
metL
Name
(GenBank) bifunctional aspartate kinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
sem
Salmonella enterica subsp. enterica serovar Typhimurium T000240
Pathway
sem00260
Glycine, serine and threonine metabolism
sem00261
Monobactam biosynthesis
sem00270
Cysteine and methionine metabolism
sem00300
Lysine biosynthesis
sem01100
Metabolic pathways
sem01110
Biosynthesis of secondary metabolites
sem01120
Microbial metabolism in diverse environments
sem01230
Biosynthesis of amino acids
Module
sem_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
sem_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
sem_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
sem00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
STMDT12_C42490 (metL)
00270 Cysteine and methionine metabolism
STMDT12_C42490 (metL)
00300 Lysine biosynthesis
STMDT12_C42490 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
STMDT12_C42490 (metL)
Enzymes [BR:
sem01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
STMDT12_C42490 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
STMDT12_C42490 (metL)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
HTH_11
Motif
Other DBs
NCBI-ProteinID:
BAJ39192
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All DBs
Position
4415965..4418397
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AA seq
810 aa
AA seq
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MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLISW
LKLSQTDRLSAHQVLQTLRRYQCDLISGLLPADAADDLTSAFISDLERLAALLDGGVTDA
VYAEIVGHGEIWSARLMSAVLNQQGLDAAWLDARAFLRAERAAQPQVDEGLSYPLLQQLL
AQHPGKRLVVTGFISRNHDGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSDIDLQLRCSYTPDQGSTRIER
VLASGTGARIVTSHDDICLIEFQVPASQDFRLAHKELDHILKRAQVRPLAVGVHRDRQLL
QFCYTAEVADSVLKLLDDVGLPGELRLRQGLALVAMVGAGVTRNPLHCHRFWQQLKGQPV
EFTWQSEEGISLVAVLRTGPTESLIQGLHQSVFRAEKRIGLMLFGKGNIGSRWLELFARE
QSTLSARTGFEFVLAGVVDSRRSLLNYEGLDASRALAFFDDEAVEQDEESLFLWMRAHPY
DDLVVLDVTASAQLADQYLDFASHGFHVISANKLAGASASDKYRQIHDAFEKTGRYWLYN
ATVGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLT
EPDPRVDLSGKDVMRKLVILAREAGYDIEPDQVRVESLVPAHCEEGSIDHFFENGDALNE
QMVQRLEAARELGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRD
NPLVIRGPGAGRDVTAGAIQSDINRLAQLL
NT seq
2433 nt
NT seq
+upstream
nt +downstream
nt
atgagtgtgattgcgcaggcaggggcgaaaggtcgtcaactgcataaatttggcggcagt
agtctggcggatgtgaagtgttacctgcgtgtcgcaggcattatggcggagtattcgcag
cctgacgatatgatggtagtgtccgccgcaggcagtaccaccaaccagttgattagctgg
ctcaagttaagccagaccgatcgcctttctgcgcatcaggtattacagacgttacgccgc
taccagtgcgatctgattagcgggctgcttcccgccgacgcggcagatgatttaaccagc
gcttttattagcgatctggaacgtcttgccgccttgctcgacggcggcgtaacggatgcc
gtctatgctgagatcgtcggacacggcgaaatttggtcggcgagattgatgtccgccgtc
ctgaatcagcaggggctggatgccgcctggctggacgcgcgcgcatttttacgcgccgaa
cgcgccgcacagccgcaggttgatgaagggctatcttatcctttattgcagcagctactg
gcgcagcatccgggcaaacgtctggtcgtgaccggctttatcagccgcaatcatgacggc
gaaacagtcctgttaggccggaacggttccgactattccgccacgcaaatcggcgcgctg
gcgggcgtttcccgcgtgaccatctggagcgatgtcgcgggcgtttatagcgccgacccg
cgcaaagtgaaagatgcctgcctgctgccgttgctgcgtctggacgaagccagcgagctg
gcgcgtctggcggcgcctgttctgcacgcccgcacgctacagccagtgtccggcagcgat
atcgatttgcagttgcgctgtagctacacgccggatcaagggtcaacccgaattgaacga
gtgctggcttccgggacgggcgcgcgtatcgtgaccagtcacgatgatatctgtctgatt
gagtttcaggtgccagccagccaggatttcaggctggcgcataaagagctcgaccacatt
ttaaaacgggcgcaggtgcgtccgctggcggtgggcgtgcatcgcgatcgccagctattg
cagttctgctataccgccgaggtagcggatagcgtactgaaactcctcgacgatgtcggg
ctgccgggcgaattgcgcctgcgacaggggctggcgctggtggcgatggtcggtgcgggc
gtcactcgcaatccgctacactgccatcgcttctggcagcagttgaaaggtcagccagtg
gagtttacctggcagtcggaggagggcatcagtctggtggcggtgctgcgtaccggccca
actgagagcctgattcaggggctgcatcagtctgttttccgcgccgaaaaacgcattggc
ctgatgctgttcggtaaggggaacatcggctcccgttggctggaactgtttgcccgtgaa
caaagcacgctttccgcgcgtactggttttgaatttgtgctggcgggcgtggtggatagc
cgccgtagcctgttgaattatgaagggctggacgccagccgcgcgttggcattctttgat
gatgaagccgttgagcaggacgaagagtcgctattcctgtggatgcgtgcgcatccgtat
gatgatttagtggtgctggatgtaaccgccagtgcacagttagccgatcagtaccttgat
ttcgccagccacggttttcatgtgattagcgccaataaactggcgggcgcaagcgccagc
gataagtatcgccagattcatgacgcgtttgaaaaaaccgggcgttactggctgtataac
gccaccgtgggcgcgggattgccgatcaaccacacggtgcgggatctgattgacagcggc
gatacgattctctcgatcagcgggatcttctccgggacgctatcctggctgttcctgcaa
tttgacggtacggtgccgttcaccgatctggtggatcaggcctggcagcaggggctgacc
gaacccgatccgcgcgtcgatctttccggaaaagatgtcatgcgtaagctggtgattctg
gcgcgcgaggcgggatacgacatcgagccggatcaggtgcgtgtagaatcgttggtgccg
gcgcattgtgaagaaggatctatcgatcactttttcgaaaacggcgacgcgctgaatgaa
cagatggtgcagcgtctggaggcagcccgcgaactggggctggtgttgcgttacgtggcg
cgtttcgacgccaatggcaaagcgcgcgtcggcgttgaagcggtgcgtccggaacatccg
ctggcggcgctgctgccgtgcgataatgtctttgctattgaaagccgctggtatcgcgat
aacccgctggtgatccgtgggccgggcgcgggtcgcgatgtgaccgccggggcgattcag
tcggatatcaaccgtctggcgcagttgctgtaa
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