Streptomyces endophytica: OJ254_03050
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Entry
OJ254_03050 CDS
T09208
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
seng
Streptomyces endophytica
Pathway
seng00020
Citrate cycle (TCA cycle)
seng00630
Glyoxylate and dicarboxylate metabolism
seng00785
Lipoic acid metabolism
seng01100
Metabolic pathways
seng01110
Biosynthesis of secondary metabolites
seng01120
Microbial metabolism in diverse environments
seng01200
Carbon metabolism
seng01210
2-Oxocarboxylic acid metabolism
Module
seng_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
seng00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
OJ254_03050
00630 Glyoxylate and dicarboxylate metabolism
OJ254_03050
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
OJ254_03050
Enzymes [BR:
seng01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
OJ254_03050
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
OJ254_03050
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
OJ254_03050
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
OJ254_03050
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UZJ29635
LinkDB
All DBs
Position
683498..687340
Genome browser
AA seq
1280 aa
AA seq
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MSLQSPNTSSISNEADQAGQGKSPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADY
KPGGATAPSTPAEAPAPAGAAPAQSSPAAPAADGPKPAAAPATPAASAPAPAKPAPAKAA
EAKAAAAKPAPKPSGASTGSTGAAGAARTVAADGEAPAAGPEFVTLRGPSAAVAKNMNAS
LELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVQALKAMPSMNYSF
AQKDGKPTLVKPEHVNLGLAIDLVKPNGERQLVVAAIKKAETLSFFEFWQAYEDIVRRAR
DNKLTMDDFTGVTASLTNPGGIGTVHSVPRLMPGQSMIMGVGAMDYPAEFQGTSQDALNK
MGISKVMTLTSTYDHRVIQGAASGEFLRIMSQLLLGENDFYDEIFKSLRIPYEPIRWMRD
IDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLERE
FAVGGFSGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERQHKSPEREE
QLRILRRLNSAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMA
HRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSL
TANPSHLEAVDPVVEGVARAKQDIINKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQL
RGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARL
AFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGD
ITLEEAEQALQDFQGQLEKVFTEVRDATTAPAAPEVPQPKAEFPVFVDTAISQEVVKRIA
ESQVNIPEHITVHPRLLPQLQRRAAQVEDNAIDWGMGETLAVGSLLMEGTPVRLAGQDSR
RGTFGQRHAVLIDRETGEDYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPEAL
VMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQ
LCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKTEEFTSGGF
RPVIGDSTVKPENVRKVVFCSGKVYYDLDAERQKRGADDTAIVRIERLYPLPGKELQAEI
AKFPNAEKYLWAQEEPANQGAWPFLGLNLIDHLDLAVGADVPHGERLRRISRPHSSSPAV
GSAKRHQAEQAQLVAEVFDA
NT seq
3843 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacacttcgagcatctctaacgaggccgatcaagcggggcag
ggcaagagccctgctgctgccttcggccccaatgagtggctcgtcgatgagatctaccag
cagtacctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactac
aagccgggcggcgccaccgcgccgagcacgccggcggaggcccccgcccccgccggggcc
gccccggcccagtcgtcccccgcggccccggccgcggacgggccgaagcccgccgccgcg
ccggccaccccggccgcgagcgccccggcccccgccaagcccgcgccggccaaggccgcc
gaggccaaggccgccgccgcgaagcccgcgccgaagccgtccggtgcaagcaccggctcc
accggagcggctggcgccgcgcgcactgtggcggccgacggcgaggccccggccgccggt
cccgagttcgtcaccctgcgcggcccgtcggccgccgttgcgaagaacatgaacgcctcc
ctggagctgccgacggccacgtccgtccgcgcggtcccggtgaagctgctcttcgacaac
cgcatcgtcatcaacaaccacctcaagcgcgcccggggcgggaaggtctccttcacccac
ctcatcgggtacgcgatggtgcaggccctcaaggccatgccgtcgatgaactactccttc
gcgcagaaggacggcaagccgaccctggtcaagcccgagcacgtcaacctcggcctggcc
atcgacctggtgaagccgaacggcgagcgccagctggtcgtcgccgccatcaagaaggcc
gagacgctctcgttcttcgagttctggcaggcctacgaggacatcgtccgccgggcccgg
gacaacaagctgacgatggacgacttcaccggagtcaccgcgtcgctgaccaaccccggc
ggcatcggtacggtccactccgtgccgcgcctgatgcccggccagtcgatgatcatgggc
gtcggcgcgatggactaccccgccgagttccagggcacctcgcaggacgccctgaacaag
atgggcatctccaaggtcatgacgctgaccagcacctatgaccaccgcgtgatccagggc
gccgcctccggcgagttcctgcgcatcatgagccagctgctgctcggcgagaacgacttc
tacgacgagatcttcaagtcgctgcggatcccgtacgagccgatccgctggatgcgcgac
atcgacgcgtcgcacgacgacgacgtcaccaaggccgcacgggtcttcgagctgatccac
tcctaccgggtccgcggccacgtcatggccgacaccgacccgctggagtaccaccagcgc
aagcaccccgacctggacatcaccgagcacggcctcaccctgtgggacctggagcgggag
ttcgcggtcggcggcttctccggcaagtccatgatgaagctgcgcgacatcctgggcgtg
ctgcgcgactcgtactgccgcaccaccggcatcgagttcatgcacatccaggaccccaag
cagcgcaagtggatccaggaccgggtcgagcgtcagcacaagtcgcccgagcgcgaggag
cagctgcgcatcctgcgccggctgaactccgccgaggcgttcgagacgttcctgcagacc
aagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtcatcccgctgctg
gacgcggtcatcgactccgcggccgagtcgcggctggacgaggtcgtcatcggcatggcc
caccgcggccgcctcaacgtcctcgccaacatcgtcggcaagtcctacgcgcagatcttc
cgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgacgtgaagtac
cacctgggcgccgagggcaccttcaccggcctggacggcgagcagatcaaggtctcgctg
accgccaacccctcccacctggaggccgtggacccggtcgtcgagggtgtcgcgcgcgcc
aagcaggacatcatcaacaagggcggcacggacttcaccgtcctgccgatccagctgcac
ggtgacgcggcgttcgccggccagggcgtggtcgccgagacgctgaacatgtcgcagctg
cgcggctaccgcaccggcggcacggtgcacgtcgtcatcaacaaccaggtcggcttcacc
gccgccccggagtcgtcgcgctcctccatgtacgccaccgacgtggcccgcatgatcgag
gcgccgatcttccacgtgaacggtgacgaccccgaggccgtcgtccgcgtcgcccgtctg
gccttcgagttccgccaggcgttcaacaaggacgtggtcatcgacctcatctgctaccgc
cgccgcggccacaacgagtcggacaacccggccttcacccagccgctgatgtacgacctg
atcgacaagaagcgctcggtgcgcaagctctacaccgagtcgctgatcggccgtggcgac
atcaccctcgaagaggcggagcaggcgctccaggacttccagggacagctggagaaggtc
ttcaccgaggtccgcgacgccacgacggctccggccgcccccgaggtgccgcagcccaag
gcggagttcccggtcttcgtcgacaccgcgatctcccaggaggtcgtcaagcggatcgcc
gagtcgcaggtcaacatccccgagcacatcaccgtgcacccgcgtctgctgccccagctg
cagcgccgcgcggcccaggtcgaggacaacgcgatcgactggggcatgggcgagaccctc
gccgtcggttcgctgctgatggagggcaccccggtccggctcgccggccaggactcccgc
cgcggcacgttcggccagcggcacgcggtgctcatcgaccgcgagaccggcgaggactac
accccgctgctctacctctccgaggaccaggcccgcttcaacgtctacgactcgctgctg
agcgagtacgcggcgatgggcttcgagtacggctactcgctggcccgccccgaggcgctg
gtcatgtgggaggcccagttcggtgacttcgtcaacggcgcgcagaccgtcgtcgacgag
ttcatctcctcggccgagcagaagtggggccagacctccggcgtcaccctcctcctgccg
cacggctacgagggccagggcccggaccactcctcggcccggatcgagcggttcctgcag
ctctgcgcgcagaacaacatgaccgtggcgatgccgacgctgccctccaactacttccac
ctgctgcgctggcaggtgcacaacccgcaccacaagccgctcatcgtcttcaccccgaag
tcgatgctgcgtctgaaggccgcggcgtcgaagacggaggagttcacctcgggcggcttc
cgtccggtgatcggcgactccacggtcaagcccgagaacgtccgcaaggtcgtcttctgc
tccggcaaggtctactacgacctggacgccgagcggcagaagcggggcgcggacgacacc
gcgatcgtccgcatcgagcggctctacccgctgcccggcaaggagctccaggcggagatc
gccaagttcccgaacgccgagaagtacctgtgggcgcaggaagagccggcgaaccagggt
gcctggccgttcctcggcctcaacctgatcgaccacctcgacctggcggtcggtgccgac
gtcccgcacggcgagcggctgcggcgcatctcgcgcccgcactcctcgtccccggccgtc
ggctccgccaagcgccaccaggccgagcaggcccagctggtcgcggaggtcttcgacgcg
tag
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