KEGG   Streptomyces endophytica: OJ254_20160
Entry
OJ254_20160       CDS       T09208                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
seng  Streptomyces endophytica
Pathway
seng00270  Cysteine and methionine metabolism
seng00450  Selenocompound metabolism
seng00670  One carbon pool by folate
seng01100  Metabolic pathways
seng01110  Biosynthesis of secondary metabolites
seng01230  Biosynthesis of amino acids
seng04980  Cobalamin transport and metabolism
seng04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:seng00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    OJ254_20160 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    OJ254_20160 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    OJ254_20160 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    OJ254_20160 (metH)
   04980 Cobalamin transport and metabolism
    OJ254_20160 (metH)
Enzymes [BR:seng01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     OJ254_20160 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding DUF2497 Tautomerase_2
Other DBs
NCBI-ProteinID: UZJ32167
LinkDB
Position
4511566..4515075
AA seq 1169 aa
MASNTPSSTHTARIESLREALASRVVVADGAMGTMLQAQDPTMEDFQQLEGCNEILNLTR
PDIVRSVHEEYFAVGVDCVETNTFGANHAALAEYDIPERVYELSESGARIAREVADEFTA
STGQQRYVLGSMGPGTKLPTLGHAPYVTLRDAYQQNAEGMIAGGADALLVETTQDLLQTK
AAILGARRALKATGTDLPVICSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATGP
AEMSEHLRYLARHSRIPLSCMPNAGLPVLGKDGAHYPLTPQELADAQETFVAEYGLSLVG
GCCGTTPEHLRQVVERVRDLTPPERRPRPEPGAASLYQTVPFRQDTSYLAIGERTNANGS
KKFREAMLDGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTLPI
VLDSTEVPVIQAGLEKLGGRAVINSVNYEDGDGPESRFAKVTALAAEHGAALIALTIDEE
GQARTAEKKVEIAERLIDDLTGNWGIHESDILIDCLTFTICTGQEESRKDGIATIEAIRE
LKRRHPEVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIARLEE
EQVKAALDLIHDRRSEGYDPLQKLMELFEGATAKSLKAGKAEELAALPLEERLKRRIIDG
EKNGLEADLDTALQDRPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAY
LEPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILEAA
EEHRADVIGMSGLLVKSTVIMKENLEELNQRKMAADYPVILGGAALTRAYVEQDLHEIYE
GEVRYARDAFEGLRLMDALIAVKRGVPGAALPELKQRRVPKRDTAVLEVEEPEGAVRSDV
ATDNPVPAPPFWGTRVVKGIQLADYASWLDEGALFKGQWGLKQARTGEGPTYEELVETEG
RPRLRGWLDKLQTENLLEAAVVHGYFPCVSKGEDLILLHEDGTERTRFTFPRQRRGRRLC
LADYFRPEESGETDVVGLQVVTVGSRIGAATAELFEANSYRDYLELHGLSVQLAEALAEY
WHARVRAELGFGGEDPNDIEDMFALKYRGARFSLGYGACPDLEDRAKIADLLEPERIGVQ
LSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3510 nt   +upstreamnt  +downstreamnt
atggcctcgaacacgccatcgtccacccacaccgcccgcatcgaatcgctgcgtgaggcc
ctggcctcgcgggtggtggtcgccgacggggcgatgggcaccatgctgcaggcccaggac
ccgaccatggaggacttccagcagctggagggctgcaacgagatcctcaacctcacccgg
cccgacatcgtccgctcggtgcacgaggagtacttcgcggtcggcgtcgactgcgtcgag
accaacacgttcggcgcaaaccacgccgccctcgccgagtacgacatccccgagcgggtc
tacgagctgtccgagtccggcgcccggatcgcccgcgaggtcgccgacgagttcaccgcc
tccaccggccagcagcgctacgtcctgggctccatgggccccggcaccaagctgcccacc
ctcggccacgccccctacgtcaccctccgtgacgcctaccagcagaacgccgagggcatg
atcgccggcggcgcggacgccctgctcgtcgagaccacccaggacctgctgcagaccaag
gccgccatcctgggcgcccgccgcgccctgaaggccaccggcaccgacctcccggtgatc
tgctcggtcaccgtcgagaccaccggcaccatgctgctgggctccgagatcggcgcggcg
ctgaccgcgctggaaccgctcggcatcgacatgatcggcctgaactgcgccaccggcccg
gccgagatgagcgagcacctgcgctacctcgcccggcactcccgcatcccgctgtcctgc
atgcccaacgcgggcctgccggtgctcggcaaggacggcgcccactacccgctcacgccc
caggagctggccgacgcccaggagaccttcgtcgccgagtacggcctgtcgctggtcggc
ggctgctgcggaacgacgcccgagcacctgcgccaggtcgtggagcgggtccgcgacctc
accccgcccgagcgccggccgcgccccgagccgggcgccgcgtcgctgtaccagaccgtg
ccgttccgccaggacacctcctacctggcgatcggcgagcggaccaacgccaacggctcg
aagaagttccgcgaggcgatgctggacggccgctgggacgactgcgtggagatggcccgc
gaccagatccgcgagggcgcccacatgctcgacctgtgcgtcgactacgtgggccgggac
ggcgtcgccgacatggaggagctggccggccgcttcgccaccgcctccaccctgcccatc
gtcctggactccaccgaggtaccggtcatccaggccggcctggagaagctgggcggccgc
gcggtgatcaactccgtcaactacgaggacggtgacggccccgagtcgcgcttcgccaag
gtcaccgcgctcgccgccgagcacggcgcggcgctgatcgcgctgaccatcgacgaggag
ggccaggcccgcaccgccgagaagaaggtggagatcgccgagcggctgatcgacgacctg
accggcaactggggcatccacgagagcgacatcctcatcgactgtctgaccttcacgatc
tgcaccggtcaggaggagtcccgcaaggacggcatcgccacgatcgaggccatccgcgag
ctcaagaggcgccaccccgaggtgcagaccaccctgggcctgtccaacatctccttcggc
ctcaacccggccgcccggatcgtgctgaactccgtcttcctcgacgagtgcgtcaaggcc
ggcctggactcggccatcgtgcacgcctccaagatcctgccgatcgcccggctggaggag
gagcaggtcaaggccgccctcgacctgatccacgaccggcgcagcgagggctacgacccg
ctgcagaagctgatggagctcttcgagggcgccaccgccaagtcgctgaaggccggcaag
gccgaggaactggccgcgctgccgctggaggagcgcctgaagcggcgcatcatcgacggc
gagaagaacggcctggaggccgacctcgacacggccctgcaggaccgccccgccctcgac
atcgtcaacgacaccctcctggacggcatgaaggtcgtcggcgagctcttcggctccggc
cagatgcagctgccgttcgtgctgcagtccgccgaggtcatgaagaccgcggtggcctac
ctggagccgcacatggagaagtccgacgacgagggcaagggcaccatcgtcctggccacc
gtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctgtccaacaac
ggctacaacgtcgtcaacctcggcatcaagcagccggtctcggcgatcctggaggccgcc
gaggaacaccgggccgacgtcatcggcatgtccgggctcctggtcaagtccacggtgatc
atgaaggagaacctggaggagctcaaccagcgcaagatggcggccgactaccccgtcatc
ctcggcggcgctgccctcacccgcgcctacgtcgagcaggacctgcacgagatctacgag
ggcgaggtccgctacgcccgcgacgcgttcgagggcctgcggctgatggacgccctgatc
gccgtcaagcgcggggtgcccggcgcggccctccccgagctcaagcagcgccgggtcccc
aagcgcgacacggccgtcctggaggtcgaggagcccgagggcgcggtgcgctccgacgtc
gccaccgacaacccggtccccgccccgccgttctggggcacccgggtcgtcaagggcatc
cagctcgccgactacgcctcctggctggacgagggcgccctcttcaagggccagtggggc
ctcaagcaggcccgcaccggcgagggtccgacgtacgaggagctggtggagaccgagggc
cgcccgcggctgcgcggctggctcgacaagctgcagaccgagaacctcctggaggccgcg
gtcgtccacggctacttcccctgcgtctccaagggcgaggacctgatcctgctgcacgag
gatggcaccgagcggacccgcttcaccttcccgcgccagcgccgcggccgccggctgtgc
ctggcggactacttccgcccggaggagtccggcgagaccgacgtcgtcggcctccaggtc
gtcaccgtcggctcccggatcggcgccgccaccgccgagctcttcgaggccaactcctac
cgcgactacctcgaactgcacggcctgtccgtccagttggccgaggcgctggccgagtac
tggcacgcccgggtccgtgccgagctgggcttcggcggcgaggacccgaacgacatcgag
gacatgttcgcgctcaagtaccgcggcgcccgcttctcgctgggctacggcgcctgcccc
gacctggaggaccgcgccaagatcgccgacctgctggagcccgagcggatcggggtccag
ctgtccgaggagttccagctgcacccggagcagtccacggacgccatcgtgatccaccac
ccggaggcgaagtacttcaacgccaggtga

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