Streptomyces endophytica: OJ254_20160
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Entry
OJ254_20160 CDS
T09208
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
seng
Streptomyces endophytica
Pathway
seng00270
Cysteine and methionine metabolism
seng00450
Selenocompound metabolism
seng00670
One carbon pool by folate
seng01100
Metabolic pathways
seng01110
Biosynthesis of secondary metabolites
seng01230
Biosynthesis of amino acids
seng04980
Cobalamin transport and metabolism
seng04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
seng00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
OJ254_20160 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
OJ254_20160 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
OJ254_20160 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
OJ254_20160 (metH)
04980 Cobalamin transport and metabolism
OJ254_20160 (metH)
Enzymes [BR:
seng01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
OJ254_20160 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
DUF2497
Tautomerase_2
Motif
Other DBs
NCBI-ProteinID:
UZJ32167
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All DBs
Position
4511566..4515075
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AA seq
1169 aa
AA seq
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MASNTPSSTHTARIESLREALASRVVVADGAMGTMLQAQDPTMEDFQQLEGCNEILNLTR
PDIVRSVHEEYFAVGVDCVETNTFGANHAALAEYDIPERVYELSESGARIAREVADEFTA
STGQQRYVLGSMGPGTKLPTLGHAPYVTLRDAYQQNAEGMIAGGADALLVETTQDLLQTK
AAILGARRALKATGTDLPVICSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCATGP
AEMSEHLRYLARHSRIPLSCMPNAGLPVLGKDGAHYPLTPQELADAQETFVAEYGLSLVG
GCCGTTPEHLRQVVERVRDLTPPERRPRPEPGAASLYQTVPFRQDTSYLAIGERTNANGS
KKFREAMLDGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTLPI
VLDSTEVPVIQAGLEKLGGRAVINSVNYEDGDGPESRFAKVTALAAEHGAALIALTIDEE
GQARTAEKKVEIAERLIDDLTGNWGIHESDILIDCLTFTICTGQEESRKDGIATIEAIRE
LKRRHPEVQTTLGLSNISFGLNPAARIVLNSVFLDECVKAGLDSAIVHASKILPIARLEE
EQVKAALDLIHDRRSEGYDPLQKLMELFEGATAKSLKAGKAEELAALPLEERLKRRIIDG
EKNGLEADLDTALQDRPALDIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAY
LEPHMEKSDDEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILEAA
EEHRADVIGMSGLLVKSTVIMKENLEELNQRKMAADYPVILGGAALTRAYVEQDLHEIYE
GEVRYARDAFEGLRLMDALIAVKRGVPGAALPELKQRRVPKRDTAVLEVEEPEGAVRSDV
ATDNPVPAPPFWGTRVVKGIQLADYASWLDEGALFKGQWGLKQARTGEGPTYEELVETEG
RPRLRGWLDKLQTENLLEAAVVHGYFPCVSKGEDLILLHEDGTERTRFTFPRQRRGRRLC
LADYFRPEESGETDVVGLQVVTVGSRIGAATAELFEANSYRDYLELHGLSVQLAEALAEY
WHARVRAELGFGGEDPNDIEDMFALKYRGARFSLGYGACPDLEDRAKIADLLEPERIGVQ
LSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq
3510 nt
NT seq
+upstream
nt +downstream
nt
atggcctcgaacacgccatcgtccacccacaccgcccgcatcgaatcgctgcgtgaggcc
ctggcctcgcgggtggtggtcgccgacggggcgatgggcaccatgctgcaggcccaggac
ccgaccatggaggacttccagcagctggagggctgcaacgagatcctcaacctcacccgg
cccgacatcgtccgctcggtgcacgaggagtacttcgcggtcggcgtcgactgcgtcgag
accaacacgttcggcgcaaaccacgccgccctcgccgagtacgacatccccgagcgggtc
tacgagctgtccgagtccggcgcccggatcgcccgcgaggtcgccgacgagttcaccgcc
tccaccggccagcagcgctacgtcctgggctccatgggccccggcaccaagctgcccacc
ctcggccacgccccctacgtcaccctccgtgacgcctaccagcagaacgccgagggcatg
atcgccggcggcgcggacgccctgctcgtcgagaccacccaggacctgctgcagaccaag
gccgccatcctgggcgcccgccgcgccctgaaggccaccggcaccgacctcccggtgatc
tgctcggtcaccgtcgagaccaccggcaccatgctgctgggctccgagatcggcgcggcg
ctgaccgcgctggaaccgctcggcatcgacatgatcggcctgaactgcgccaccggcccg
gccgagatgagcgagcacctgcgctacctcgcccggcactcccgcatcccgctgtcctgc
atgcccaacgcgggcctgccggtgctcggcaaggacggcgcccactacccgctcacgccc
caggagctggccgacgcccaggagaccttcgtcgccgagtacggcctgtcgctggtcggc
ggctgctgcggaacgacgcccgagcacctgcgccaggtcgtggagcgggtccgcgacctc
accccgcccgagcgccggccgcgccccgagccgggcgccgcgtcgctgtaccagaccgtg
ccgttccgccaggacacctcctacctggcgatcggcgagcggaccaacgccaacggctcg
aagaagttccgcgaggcgatgctggacggccgctgggacgactgcgtggagatggcccgc
gaccagatccgcgagggcgcccacatgctcgacctgtgcgtcgactacgtgggccgggac
ggcgtcgccgacatggaggagctggccggccgcttcgccaccgcctccaccctgcccatc
gtcctggactccaccgaggtaccggtcatccaggccggcctggagaagctgggcggccgc
gcggtgatcaactccgtcaactacgaggacggtgacggccccgagtcgcgcttcgccaag
gtcaccgcgctcgccgccgagcacggcgcggcgctgatcgcgctgaccatcgacgaggag
ggccaggcccgcaccgccgagaagaaggtggagatcgccgagcggctgatcgacgacctg
accggcaactggggcatccacgagagcgacatcctcatcgactgtctgaccttcacgatc
tgcaccggtcaggaggagtcccgcaaggacggcatcgccacgatcgaggccatccgcgag
ctcaagaggcgccaccccgaggtgcagaccaccctgggcctgtccaacatctccttcggc
ctcaacccggccgcccggatcgtgctgaactccgtcttcctcgacgagtgcgtcaaggcc
ggcctggactcggccatcgtgcacgcctccaagatcctgccgatcgcccggctggaggag
gagcaggtcaaggccgccctcgacctgatccacgaccggcgcagcgagggctacgacccg
ctgcagaagctgatggagctcttcgagggcgccaccgccaagtcgctgaaggccggcaag
gccgaggaactggccgcgctgccgctggaggagcgcctgaagcggcgcatcatcgacggc
gagaagaacggcctggaggccgacctcgacacggccctgcaggaccgccccgccctcgac
atcgtcaacgacaccctcctggacggcatgaaggtcgtcggcgagctcttcggctccggc
cagatgcagctgccgttcgtgctgcagtccgccgaggtcatgaagaccgcggtggcctac
ctggagccgcacatggagaagtccgacgacgagggcaagggcaccatcgtcctggccacc
gtccgcggcgacgtccacgacatcggcaagaacctcgtcgacatcatcctgtccaacaac
ggctacaacgtcgtcaacctcggcatcaagcagccggtctcggcgatcctggaggccgcc
gaggaacaccgggccgacgtcatcggcatgtccgggctcctggtcaagtccacggtgatc
atgaaggagaacctggaggagctcaaccagcgcaagatggcggccgactaccccgtcatc
ctcggcggcgctgccctcacccgcgcctacgtcgagcaggacctgcacgagatctacgag
ggcgaggtccgctacgcccgcgacgcgttcgagggcctgcggctgatggacgccctgatc
gccgtcaagcgcggggtgcccggcgcggccctccccgagctcaagcagcgccgggtcccc
aagcgcgacacggccgtcctggaggtcgaggagcccgagggcgcggtgcgctccgacgtc
gccaccgacaacccggtccccgccccgccgttctggggcacccgggtcgtcaagggcatc
cagctcgccgactacgcctcctggctggacgagggcgccctcttcaagggccagtggggc
ctcaagcaggcccgcaccggcgagggtccgacgtacgaggagctggtggagaccgagggc
cgcccgcggctgcgcggctggctcgacaagctgcagaccgagaacctcctggaggccgcg
gtcgtccacggctacttcccctgcgtctccaagggcgaggacctgatcctgctgcacgag
gatggcaccgagcggacccgcttcaccttcccgcgccagcgccgcggccgccggctgtgc
ctggcggactacttccgcccggaggagtccggcgagaccgacgtcgtcggcctccaggtc
gtcaccgtcggctcccggatcggcgccgccaccgccgagctcttcgaggccaactcctac
cgcgactacctcgaactgcacggcctgtccgtccagttggccgaggcgctggccgagtac
tggcacgcccgggtccgtgccgagctgggcttcggcggcgaggacccgaacgacatcgag
gacatgttcgcgctcaagtaccgcggcgcccgcttctcgctgggctacggcgcctgcccc
gacctggaggaccgcgccaagatcgccgacctgctggagcccgagcggatcggggtccag
ctgtccgaggagttccagctgcacccggagcagtccacggacgccatcgtgatccaccac
ccggaggcgaagtacttcaacgccaggtga
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