Salmonella enterica subsp. enterica serovar Javiana: CFSAN001992_12840
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Entry
CFSAN001992_12840 CDS
T02479
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
senj
Salmonella enterica subsp. enterica serovar Javiana
Pathway
senj00270
Cysteine and methionine metabolism
senj00450
Selenocompound metabolism
senj00670
One carbon pool by folate
senj01100
Metabolic pathways
senj01110
Biosynthesis of secondary metabolites
senj01230
Biosynthesis of amino acids
senj04981
Folate transport and metabolism
Module
senj_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
senj00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CFSAN001992_12840 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
CFSAN001992_12840 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CFSAN001992_12840 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
CFSAN001992_12840 (metH)
04980 Cobalamin transport and metabolism
CFSAN001992_12840 (metH)
Enzymes [BR:
senj01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
CFSAN001992_12840 (metH)
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GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AGF82866
LinkDB
All DBs
Position
complement(2613984..2617667)
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AA seq
1227 aa
AA seq
DB search
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAAINYAAAKLARACADEWTA
RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGVDLILI
ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQASRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAYEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
TDYAFRKGMSVEDVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcaccatgatccagagctatcgtctacatgaagaagatttccgcggggag
cgctttgccgactggccctgcgacctgaaaggcaacaatgacctgctggtactcagcaag
ccggaggtgatcgccgctatccacaacgcctactttgaggcgggcgcggatatcatcgaa
accaacacctttaactcgacaaccattgcgatggcggattaccggatggaatccctgtcg
gcggcaattaactatgcggcggccaaactggcgcgcgcctgcgccgatgaatggacggcg
cgaacaccagaaaaaccacgctttgttgcgggcgtgcttggtccaactaaccgcacggcc
tccatttcgccggacgtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtg
gcggcctaccgtgaatccaccaaagcgctggtggaaggtggcgtagatctgattctgatt
gagaccgtctttgacaccctgaatgcgaaagcggcggtgtttgcggtgaaagaagagttt
gaagcgctgggcgttgatctgccgatcatgatttccggcaccatcaccgacgcctctggt
cgcaccctctccggccagactaccgaagccttttataactcgctgcgccacgccgaggcg
ctcacttttggccttaactgcgcgctggggccagatgaactgcgccagtacgtccaggaa
ctgtcgcggattgccgaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgct
ttcggcgagtacgacctcgacgccgacaccatggcgaaacagattcgcgaatgggcggag
gcgggcttcctgaatatcgttggcggctgctgcggcaccacgccggagcatattgcggcg
atgagccgcgccgttgccggtttgccgccgcgccaactgccggatatcccggttgcctgc
cgcctttccggcctggagccgctgaacattggcgacgacagcctgtttgtcaacgtcggc
gaacgtactaacgtcaccggctcggccaaatttaaacggctgatcaaagaagagaaatac
agcgaagcgctggatgtcgcccgtcagcaggtcgaaagcggcgcgcagattattgatatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatt
gccggtgagccggatattgcccgtgtaccaatcatgatcgactcctccaaatgggaggtt
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaa
gagggcgtggaagcttttattcatcatgcgaagttgctacgtcgctacggcgcggcagtg
gtggtgatggcctttgatgagcaggggcaggccgatacccgcgagcgtaaaatcgagatt
tgccgccgggcgtacaaaattctcaccgaagaggtgggcttcccgccggaagacatcatc
ttcgacccgaatatcttcgccgtggcgaccggtattgaagagcacaacaactatgcgcag
gactttatcggcgcttgcgaagatattaaacgcgagctgccgcatgcgctgatctccggc
ggcgtgtctaacgtgtccttctcgttccgcggcaacgacccggtacgtgaggctatccac
gcggtattcctctactacgccatccgcaacggcatggacatgggcatcgtcaacgccggg
caattggcgatttatgacgacctgcctgccgaactgcgcgatgcggttgaagatgtcatt
cttaaccgtcgcgatgacggcactgagcgtttgctggatttggcggagaaataccgcggc
agcaaaaccgacgaagctgccaacgcccagcaggcggaatggcgtagctgggacgtgaaa
aagcgtctcgaatactcgctggtgaaaggcattaccgaatttatcgaacaggataccgaa
gaagcccgccagcaggcctcccgcccgattgaggtgattgaagggccgctgatggacggc
atgaacgtggtcggcgacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaa
tccgctcgcgtgatgaaacaagcggtggcttacctggagccgtttattgaagccagcaaa
gaaaaaggctccagcaacggcaagatggtcatcgccaccgtgaagggcgatgtgcacgac
attggcaagaacattgttggcgtggtgctgcaatgcaacaactacgaaatcgtcgatctt
ggcgtgatggtgccagcggagaaaatcctcagaacggcgcgtgaagtgaatgccgatctg
attggtctttccgggcttattaccccgtcgctggacgaaatggtcaacgtggcgaaagag
atggagcgtcagggctttactattccgctactgatcggcggcgcaaccacttcgaaagcg
cacaccgcggtgaaaatcgagcagaactacagcggtccgacggtctacgtgcagaatgct
tcgcgtaccgtgggcgtggtggcggcgctactctccgacacccagcgcgatgactttgtc
gcccgtacccgcaaagagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgc
acgccgccggtcacgctggaagcggcgcgcgataacgatctggcattcgattgggaacgc
tacaccccgccagtagcccaccgtctgggcgtgcaggaagtggaagccagcatcgaaact
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggccggcaaatac
ccgcgcattctggaagatgaggtggtgggcgttgaggcgcagcgtctgtttaaagacgcc
aatgatatgctggataaactgagcgccgagaaactgttgaatccgcgtggcgtggtgggc
ctgttcccggcgaaccgtgtgggtgacgacatcgaaatctatcgcgacgaaacccgtact
catgttctgacggtcagccaccacctgcgccagcagaccgagaaagttggttttgctaac
tactgtctggcggattttgtcgcgccgaaactgtccggaaaagcggactacatcggcgcg
tttgccgtcaccggcggtcttgaagaagacgctctggctgatgcttacgaagcgcaacac
gacgactataacaagatcatggtgaaagcgattgccgaccgtctggcggaagcgtttgcc
gagtacctgcatgagcgtgtacgtaaggtttactggggatatgcgccgaacgagagcctg
agtaacgacgaattaatccgcgaaaactaccaggggattcgcccggcgccgggttatcct
gcctgcccggaacataccgaaaaaggcactatctggcagctactggatgtcgaaaaacat
accgggatgaagctcaccgaatctttcgccatgtggcctggcgcgtcggtctccggctgg
tacttcagccatcctgagagcaaatacttcgcggtagcgcagatccaacgcgatcaggtg
actgattatgctttccgtaaaggaatgagcgttgaggacgttgagcggtggctggcgccg
aacctgggttacgatgcggactga
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