Salmonella enterica subsp. enterica serovar Typhimurium DT2: STMDT2_01541
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Entry
STMDT2_01541 CDS
T02869
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
senr
Salmonella enterica subsp. enterica serovar Typhimurium DT2
Pathway
senr00010
Glycolysis / Gluconeogenesis
senr00020
Citrate cycle (TCA cycle)
senr00620
Pyruvate metabolism
senr00785
Lipoic acid metabolism
senr01100
Metabolic pathways
senr01110
Biosynthesis of secondary metabolites
senr01120
Microbial metabolism in diverse environments
senr01200
Carbon metabolism
senr01210
2-Oxocarboxylic acid metabolism
Module
senr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
senr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
STMDT2_01541 (aceE)
00020 Citrate cycle (TCA cycle)
STMDT2_01541 (aceE)
00620 Pyruvate metabolism
STMDT2_01541 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
STMDT2_01541 (aceE)
Enzymes [BR:
senr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
STMDT2_01541 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
CDG06311
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Position
176243..178906
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AA seq
887 aa
AA seq
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MSERFQNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGAGASNY
INTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDV
CFNHFFRARNEQDGGDLVYFQGHISPGIYARAFLEGRLTQEQMDNFRQEVHGNGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIVNELEGIFAGAGWNVIKVMWGGRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYITFPEGSEEHKYLHERRQALHGYLPSRQPNFTEKLELPQLS
DFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNDLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETL
EGSKGKVQLLGSGSILRHVREAAQILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAITKFNIDADKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttccaaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggtcatccgtgaagaaggtgttgagcgcgctcagtatctgattgaccaactg
ctttctgaagctcgtaaaggcggcgtgaaagtcgcggcaggcgcaggggccagtaattac
atcaacactattgccgttgaagacgaaccggaatacccgggtaatctggagctggaacgt
cgcattcgttctgcgatccgctggaacgccatcatgaccgtgctgcgcgcgtctaaaaaa
gaccttgagttgggcggccacatggcgtccttccagtcttccgccacgatctatgatgtc
tgttttaaccatttcttccgtgcgcgcaacgaacaggatggcggcgacctggtgtacttc
cagggccacatctctccgggcatctacgctcgcgcgttcctggaaggtcgtctgacccag
gaacagatggataacttccgtcaggaagttcacggcaatggcctctcttcctatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtctctatgggtctgggcccaatc
ggtgctatctaccaggcgaaattcctgaaatatctggaacaccgcggcctgaaagatacc
tctaaacaaaccgtttacgccttcctcggcgacggcgagatggatgagccggaatccaaa
ggcgcgatcaccatcgccacccgtgaaaaactggacaacctggtctttgttatcaactgt
aacctgcagcgtcttgacggcccggtcaccggtaacggcaagattgttaacgaactggaa
ggcatctttgcaggtgctggctggaacgttatcaaagtcatgtggggcggtcgttgggat
gaactgctgcgtaaagacaccagcggtaagcttatccagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcttacgtgcgtgagcacttcttcggt
aaatacccggaaaccgcagccctggtggccgactggaccgatgagcagatttgggcgctg
aaccgcggtggtcacgatccgaagaaagtctatgctgcactgaaaaaagcgcaggaaacc
aaaggcaaagcgaccgtaatcctggcccataccattaaaggttacggcatgggcgacacc
gcggaaggcaaaaacatcgctcaccaggtgaagaaaatgaacatggacggcgtgcgttac
gtccgcgatcgtttcaacgtgccggttgccgatgctgatctcgaaaaactgccgtacatt
accttcccggaaggttctgaagaacacaaatacctgcatgaacgccgtcaggcgctgcat
ggctacctgccaagccgtcagccgaacttcaccgagaagttagagctgcctcaactttca
gatttcggcgcgctgctggaagagcaaagtaaagagatttccactacgatcgctttcgtg
cgtgccctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggttccgatcatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagattggtatctacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaaggtatcaacgagctgggcgcaggcgcatcctggctg
gctgcggcgacctcttacagcaccaacgatctgccgatgatcccgttctacatctactac
tctatgttcgggttccagcgtatcggcgacctgtgctggcaggctggcgaccagcaggct
cgcggcttcctgatcggcgggacttccggtcgtactacgctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcttacgcttacgaagtggctgtcatcatgcatgatggtctggagcgtatgtacggt
gagaaacaagagaacgtttactactacatcaccacgctgaacgaaaactaccacatgccg
gccatgccagcaggtgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccctc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtgcgt
gaagcagcacagatcctggcgaaagattacggcgtaggttctgacgtatatagcgtgacc
tccttcaccgaactggcgcgtgatggtcaggattgtgaacgctggaacatgctgcacccg
ctggaaaccccgcgcgttccgtacatcgctcaggtgatgaacgacgctccggctgtagca
tctactgactatatgaaactgttcgccgagcaggttcgtacttacgtaccggctgacgac
tatcgcgtactgggtacggatggtttcggccgttccgacagccgtgagaacctgcgtcac
cacttcgaagttgatgcttcttatgtggttgttgcagcgctgggcgaactggctaaacgt
ggcgaaatcgacaagaaagtggtagcggatgcgattaccaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa
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