Salmonella enterica subsp. enterica serovar Typhi Ty21a: TY21A_00815
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Entry
TY21A_00815 CDS
T02648
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sent
Salmonella enterica subsp. enterica serovar Typhi Ty21a
Pathway
sent00010
Glycolysis / Gluconeogenesis
sent00020
Citrate cycle (TCA cycle)
sent00620
Pyruvate metabolism
sent00785
Lipoic acid metabolism
sent01100
Metabolic pathways
sent01110
Biosynthesis of secondary metabolites
sent01120
Microbial metabolism in diverse environments
sent01200
Carbon metabolism
sent01210
2-Oxocarboxylic acid metabolism
Module
sent_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sent00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
TY21A_00815 (aceE)
00020 Citrate cycle (TCA cycle)
TY21A_00815 (aceE)
00620 Pyruvate metabolism
TY21A_00815 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TY21A_00815 (aceE)
Enzymes [BR:
sent01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
TY21A_00815 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
PFO_beta_C
Motif
Other DBs
NCBI-ProteinID:
AGK65793
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Position
179378..182041
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AA seq
887 aa
AA seq
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MSERFQNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEARKGGVKVAAGAGASNY
INTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDV
CFNHFFRARNEQDGGDLVYFQGHISPGIYARAFLEGRLTQEQMDNFRQEVHGNGLSSYPH
PKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIVNELEGIFAGAGWNVIKVMWGGRWD
ELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWAL
NRGGHDPKKVYAALKKAQETKGKATVILAHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRY
VRDRFNVPVADADLEKLPYITFPEGSEEHKYLHERRQALHGYLPSRQPNFTEKLELPQLS
DFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNDLPMIPFYIYY
SMFGFQRIGDLCWQAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYD
PAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETL
EGSKGKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRH
HFEVDASYVVVAALGELAKRGEIDKKVVADAITKFNIDADKVNPRLA
NT seq
2664 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaacgtttccaaaatgacgtggatccgatcgaaactcgcgactggctacaggcg
atcgaatcggttatccgtgaagaaggtgttgagcgcgctcagtatctgattgaccaactg
ctttctgaagctcgtaaaggcggcgtgaaagtcgcggcaggcgcaggggccagtaattac
atcaacactattgccgttgaagacgaaccggaatacccgggtaatctggagctggaacgt
cgcattcgttctgcgatccgctggaacgccatcatgaccgtgctgcgcgcgtctaaaaaa
gaccttgagttgggcggccacatggcgtccttccagtcttccgccacgatctatgatgtc
tgttttaaccatttcttccgtgcgcgcaacgaacaggatggcggcgacctggtgtacttc
cagggccacatctctccgggcatctacgctcgcgcgttcttggaaggtcgtctgacccag
gaacagatggataacttccgtcaggaagttcacggcaatggcctctcttcctatccgcac
ccgaaactgatgccggaattctggcagttcccgaccgtctctatggggctgggcccaatc
ggtgctatctaccaggcgaaattcctgaaatatctggaacaccgtggcctgaaagatacc
tctaaacagaccgtttacgccttcctcggcgacggcgagatggatgagccggaatccaaa
ggcgcgatcaccatcgccacccgtgaaaaactggacaacctggtttttgttatcaactgt
aacctgcagcgtcttgacggcccggtcaccggtaacggcaagattgttaacgaactggaa
ggcatctttgcaggtgctggctggaacgttatcaaagtcatgtggggcggtcgttgggat
gaactgctgcgtaaagacaccagcggtaaactgatccagctgatgaacgaaaccgttgac
ggcgactaccagaccttcaaatccaaagacggcgcttacgtgcgtgagcacttcttcggt
aaatatccggaaaccgccgcgctggtggccgactggactgacgagcagatttgggcgctg
aaccgtggtggtcacgatccgaagaaagtctacgcggcactgaaaaaagcgcaggaaacc
aaaggcaaagcgaccgtaatcctggcccataccattaaaggttacggcatgggtgacacc
gcggaaggtaaaaacatcgctcaccaggttaagaaaatgaacatggacggcgtgcgttac
gtccgcgatcgtttcaacgtgccggttgccgatgctgatctcgaaaaactgccgtacatt
accttcccggaaggttctgaagaacacaaatacctgcatgaacgccgtcaggcgctgcac
ggctacctgccaagccgtcagccgaacttcaccgagaagttagagctgcctcaactttca
gatttcggcgcgctgctggaagagcaaagtaaagagatttccactacgatcgctttcgtg
cgtgccctgaacgtgatgctgaagaacaagtcgatcaaagatcgtctggttccgatcatc
gccgacgaagcgcgtactttcggtatggaaggtctgttccgtcagattggtatctacagc
ccgaacggccagcagtacaccccgcaggaccgtgagcaggttgcttactacaaagaagac
gagaaaggccagattctgcaggaaggtatcaacgagctgggcgcaggcgcatcctggctg
gctgcggcgacctcttacagcaccaacgatctgccgatgatcccgttctacatctactac
tctatgttcgggttccagcgtatcggcgacctgtgctggcaggctggcgaccagcaggct
cgcggcttcctgattggcgggacttccggtcgtactacgctgaacggcgaaggtctgcag
cacgaagatggtcacagccacattcagtcgctgactatcccgaactgtatctcttacgac
ccggcttacgcttatgaagtggctgtcatcatgcatgatggtctggagcgtatgtacggt
gaaaaacaagagaacgtttactactacatcaccaccctgaacgaaaactaccacatgccg
gcaatgccagcaggtgccgaggaaggtatccgtaaaggtatctacaaactcgaaaccctc
gaaggtagcaaaggtaaagttcagctgctgggctccggttctatcctgcgtcacgtccgt
gaagcggcagagatcctggcgaaagattacggcgtaggttctgacgtatatagcgtgacc
tccttcaccgaactggcgcgtgatggtcaggattgtgagcgctggaacatgctgcacccg
ctggaaaccccgcgcgtaccgtacatcgctcaggtgatgaacgacgctccggctgtggca
tctactgactatatgaaactgttcgccgagcaggttcgtacttacgtaccggctgacgac
tatcgcgtactgggtacggatggcttcggtcgttccgacagccgtgagaacctgcgtcac
catttcgaagttgatgcttcttatgtggttgtcgcagcgctgggcgaactggctaaacgt
ggcgaaatcgacaagaaagtggtagcggatgcgattaccaaattcaacatcgatgcagat
aaagttaacccgcgtctggcgtaa
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