KEGG   Salmonella enterica subsp. enterica serovar Typhimurium 14028S: STM14_5035
Entry
STM14_5035        CDS       T01714                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
seo  Salmonella enterica subsp. enterica serovar Typhimurium 14028S
Pathway
seo00270  Cysteine and methionine metabolism
seo00450  Selenocompound metabolism
seo00670  One carbon pool by folate
seo01100  Metabolic pathways
seo01110  Biosynthesis of secondary metabolites
seo01230  Biosynthesis of amino acids
seo04981  Folate transport and metabolism
Module
seo_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:seo00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    STM14_5035 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    STM14_5035 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    STM14_5035 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    STM14_5035 (metH)
   04980 Cobalamin transport and metabolism
    STM14_5035 (metH)
Enzymes [BR:seo01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     STM14_5035 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ACY91376
UniProt: A0A0F6BA24
LinkDB
Position
4421773..4425561
AA seq 1262 aa
MGGKLNMSHVARCSLFRQHALCQYGSLRGALSGASVSSKVEQLRAQLNERILVLDGGMGT
MIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFN
STTIAMADYRMESLSAEINYAAAKLARACADEWTARTPEKPRFVAGVLGPTNRTASISPD
VNDPAFRNITFDQLVAAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGV
DLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIA
ECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAV
AGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALD
VARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGL
KCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAY
KILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNV
SFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRD
DGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQ
AARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASKEKGSS
NGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLIGLSG
LITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVG
VVAALLSDTQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPV
AHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLD
KLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANYCLAD
FVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKAIADRLAEAFAEYLHE
RVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKL
TESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYAFRKGMSVEDVERWLAPNLGYD
AD
NT seq 3789 nt   +upstreamnt  +downstreamnt
gtgggtggcaagctgaacatgtctcatgttgcccgttgttctcttttccgccagcacgct
ttgtgccagtatggctcgttacgtggagcgttgtcgggagcgagtgtgagcagcaaagtt
gaacaactgcgtgcgcagttaaatgaacgtattctggtgctggacggcggtatgggcact
atgatccagagctatcgtctacatgaagaagatttccgcggggagcgctttgccgactgg
ccctgcgacctgaaaggcaacaatgacctgctggtcctcagcaagccggaggtgatcgcc
gctatccacaacgcctactttgaggctggcgcggatatcatcgaaaccaacacctttaac
tcgacaaccattgcgatggcggattaccggatggaatccctgtcggcggaaattaactat
gcggcggccaaactggcgcgcgcctgcgccgatgaatggacggcgcgaacaccagaaaaa
ccacgctttgttgcgggcgtgcttggtccaactaaccgcacggcctccatttcgccggac
gtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtggcggcctaccgtgaa
tccaccaaagcgctggtggaaggtggcgcagatctgattctgattgagaccgtttttgac
accctgaatgcgaaagcggcggtgtttgcggtgaaagaagagtttgaagcgctgggcgtt
gacctgccgatcatgatttccggcaccatcaccgacgcctctggccgtacgctttccggc
cagactaccgaagccttttataactcgctgcgccacgccgaggcgctcacttttggcctt
aactgcgcactggggccagatgaactgcgccagtacgtccaggaactgtcgcggattgcc
gaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgctttcggcgagtatgac
ctcgacgccgacaccatggcgaaacagattcgcgaatgggcggaagcgggcttcctgaat
atcgttggcggctgctgcggcaccacgccggagcatattgcggcgatgagccgcgccgtt
gccggtttgctgccgcgccagctgccggatatcccggtcgcctgccgcctttccggcctg
gagccgctgaacattggcgacgatagcctgtttgtgaacgtcggcgaacgtactaacgtc
accggctcggccaaatttaaacggctgatcaaagaagagaaatacagcgaagcgctggat
gtcgcccgtcagcaggtagaaagcggcgcgcagattattgatatcaatatggatgagggg
atgctcgacgccgaagcggcgatggtgcgtttcctcagcctgattgccggtgagccggac
attgcccgtgtaccaatcatgatcgactcctccaaatgggaggttatcgaaaaagggctg
aagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaagagggcgtggaagcc
tttattcatcatgcgaagcttctgcgtcgctacggcgcggcagtggtggtgatggccttt
gatgagcaggggcaggccgatacccgcgcgcgtaaaatcgaaatttgccgccgagcctac
aaaattctcaccgaagaggtgggtttcccgccggaagacatcatcttcgacccgaatatc
ttcgccgtggcgaccggtattgaagagcacaacaactacgcgcaggactttatcggcgct
tgcgaagacatcaaacgcgagctgccgcacgcgctgatctccggcggcgtgtctaacgtg
tccttctcgttccgcggcaacgacccggtacgtgaggctatccacgcggtattcctctac
tacgccatccgcaacggtatggacatgggcatcgtcaacgccggacagctggctatctac
gacgacctgcccgccgagctgcgcgatgcggttgaagatgtcattcttaaccgtcgcgat
gacggcactgagcgtttgctggatttggcggagaaataccgcggcagcaaaaccgacgaa
gctgccaacgcccagcaggcggaatggcgtagctgggacgtgaaaaagcgtctcgaatac
tcgctggtgaaaggcattaccgaatttatcgaacaggataccgaagaagcccgtcagcag
gccgcccgcccgattgaggtgattgaagggccgttgatggacggcatgaacgtggtcggc
gacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaatccgctcgcgtgatg
aaacaagcggtggcctacctggagccgtttattgaagccagcaaagaaaaaggctccagc
aacggcaagatggtgatcgccaccgtgaagggcgatgtgcacgatattggtaaaaatatc
gttggcgtggtgctgcaatgtaacaactacgaaatcgtcgatcttggcgtgatggtgcca
gcggagaaaatcctcagaacggcgcgtgaagtgaatgccgatctgatcggtctttccggg
ctgattaccccgtcgctggacgaaatggtcaacgtggcgaaagagatggagcgtcagggc
tttactatcccgctactgatcggcggcgcaaccacttcgaaagcgcatacggcggtgaaa
atcgagcagaactacagcggtccgacggtctacgtgcagaatgcttcgcgtaccgtgggc
gtggtggcggcgctactctccgacacccagcgtgatgactttgtcgcccgtacccgcaaa
gagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgcacgccgccggtcacg
ctggaggcggcgcgcgataacgatctggcattcgattgggaacgctacaccccgccggta
gcccaccgtctgggcgtgcaggaggtggaagccagcatcgaaactctgcgcaactatatc
gactggacgccgttctttatgacctggtcgctggccggcaaatacccgcgcattctggaa
gatgaggtggtgggcgttgaggcgcagcgtctgtttaaagacgccaatgatatgctggat
aaactgagcgccgagaaactgttgaatccgcgtggcgtggtgggcctgttcccggcgaac
cgtgtgggtgacgacatcgaaatctatcgcgacgaaacccgtactcatgttctgacggtc
agccaccacctgcgccagcagaccgagaaagtcggttttgccaactactgtctggcggat
tttgtcgcgccgaaactgagcggcaaagcggattacatcggtgctttcgcggtgaccggc
ggtctggaggaggatgcgctggcggacgccttcgaagcgcaacacgacgactataacaag
atcatggtgaaagcgattgccgaccgtctggcggaagcgttcgcggaatatctgcatgag
cgtgtacgtaaggtttactggggatatgcgccgaacgagagcctgagtaacgacgaatta
atccgcgaaaactaccaggggattcgcccggcgccgggttatcctgcctgcccggaacat
accgaaaaaggcactatctggcagctactggatgtcgaaaaacacaccgggatgaagctc
accgaatctttcgccatgtggccaggcgcgtcggtctccggctggtacttcagccatcct
gagagcaaatacttcgcggtagcgcagatccaacgcgatcaggtgacagattatgctttc
cgtaaaggaatgagcgttgaggatgttgagcggtggctcgcgccgaacctgggttacgat
gcggactga

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