Serratia sp. FS14: L085_00885
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Entry
L085_00885 CDS
T03313
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
serf
Serratia sp. FS14
Pathway
serf00260
Glycine, serine and threonine metabolism
serf00261
Monobactam biosynthesis
serf00270
Cysteine and methionine metabolism
serf00300
Lysine biosynthesis
serf01100
Metabolic pathways
serf01110
Biosynthesis of secondary metabolites
serf01120
Microbial metabolism in diverse environments
serf01230
Biosynthesis of amino acids
Module
serf_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
serf_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
serf_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
serf00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
L085_00885 (thrA)
00270 Cysteine and methionine metabolism
L085_00885 (thrA)
00300 Lysine biosynthesis
L085_00885 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
L085_00885 (thrA)
Enzymes [BR:
serf01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
L085_00885 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
L085_00885 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
AIA45642
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All DBs
Position
complement(202683..205142)
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADIMESNARQGQVATVLSAPAKITNHLVAMIDKTVAGQDI
LPNISDAERIFADLLSGLAQALPGFEYDRLKGVVDQEFAQLKQVLHGVSLLGQCPDSVNA
AIICRGEKLSIAIMEGVFRAKGYPVTVINPVEKLLAQGHYLESTVDIAESTLRIAAAAIP
ADHIVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRTV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTSNPQAPGTLIGKDST
DADMPVKGITNLNNMAMINVSGPGMKGMVGMAARVFAVMSRAGISVVLITQSSSEYSISF
CVPQGELQRARRALEEEFYLELKDGVLDPLDVMERLAIISVVGDGMRTLRGISARFFSAL
ARANINIVAIAQGSSERSISVVVSNDSATTGVRVSHQMLFNTDQVIEVFVIGVGGVGGAL
IEQIYRQQPWLKQKHIDLRVCGIANSRVMLTNVHGIALDSWRDELAGAQEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYVDFLADGFHVVTPNKKANTSSMNYYQQLRAAAAGSH
RKFLYDTNVGAGLPVIENLQNLLNAGDELVRFSGILSGSLSFIFGKLDEGLSLSAATLQA
RANGYTEPDPRDDLSGMDVARKLLILAREAGYKLELSDIEVEPVLPPSFDASGDVEHFLA
RLPELDKEFARNVANAAEQGKVLRYVGLIDEGRCKVRIEAVDGNDPLYKVKNGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaatttggcggaacctcggtggcgaatgcagaacgttttctgcgcgtc
gccgacatcatggagagtaatgcgcgtcagggacaggtagccacggtcttgtccgccccc
gcaaagatcaccaaccatctggtggcaatgatcgacaaaacggtggcgggccaggacatt
ctgccgaatatcagcgacgccgagcggatctttgccgacctgctgagcggcctggcgcag
gcgctgccgggctttgaatacgatcgtttgaaaggcgtggtcgatcaggagttcgcgcag
ctcaaacaggtgttgcacggggtctcgctgttgggtcagtgcccggacagcgtcaacgcg
gcgatcatctgccgcggcgaaaagctctccatcgccatcatggaaggggtgttccgcgcc
aagggttatccggtcacggtgatcaacccggtggagaaactgctggcgcagggccactac
ctggagtctaccgtggatatcgccgagtccacgctgcgcatcgccgccgcggcgatcccg
gccgaccacatcgtgctgatggccggtttcaccgccggtaacgacaagggtgagctggtg
gtgctgggccgcaacggctccgactattccgccgcggtgctggccgcctgcctgcgcgcc
gactgttgcgaaatctggactgacgtcgacggcgtgtatacctgcgatccgcgcaccgtg
ccggacgccaggctgctgaaatcgatgtcgtaccaggaggcgatggagctttcctatttc
ggcgccaaagtgctgcaccctcgcaccatcacgccgattgcccaattccaaattccttgc
ctgataaaaaacacctccaacccgcaggctcccggcacgctgatcggcaaagacagcacc
gatgccgatatgccggtgaaaggcatcaccaacctgaataatatggcgatgatcaacgtc
tccggcccgggcatgaaaggcatggtcggcatggctgcgcgggtgttcgccgtgatgtcg
cgcgccggcatttcggtggtgttgatcacccaatcctcttccgaatacagcatcagcttc
tgcgtgccgcagggcgaactgcagcgcgcccgccgcgcgctggaggaggagttctatctg
gaattgaaagatggcgtgctggatccgctggacgtcatggagcgcctggcgatcatctcg
gtagtcggcgacggcatgcgcaccctgcgtggcatttcagcgcgcttcttctccgcgctg
gcgcgcgccaacatcaatatcgtcgccatcgcccagggctcttccgagcgttcaatctcg
gtggtggtcagcaatgattccgccaccaccggcgtgcgcgtcagccaccagatgctgttc
aacaccgatcaggtgatcgaagtgttcgtcatcggcgtcggcggcgtcggcggggcgctg
atcgagcagatctaccgccagcagccgtggctgaagcaaaaacatatcgatctgcgggtg
tgcggcatcgccaactcgcgcgtgatgctgaccaacgtgcacggcatcgcgctggacagc
tggcgggacgagctggccggcgcgcaggagccgttcaatctcggccgcctgatccggctg
gtgaaggagtatcacctgctgaacccggtgatcgtcgactgtacctccagccaggcggtg
gccgatcagtatgtggacttcctggcggacggcttccatgtggtgacgccgaacaaaaag
gccaacacctcgtcgatgaactattatcagcaactgcgcgccgccgccgccggttcgcac
cgcaagttcctctacgacaccaacgtcggcgccggtctgccggtgatcgagaacctgcaa
aacctgctgaacgccggcgatgagctggtgcgtttctccggcatcctgtccggttcgctg
tcctttatttttggcaagctggatgaagggctgtcgctgtcggcggcgactctgcaggcc
agagccaatggctacaccgagccggatccgcgcgacgatctgtccggtatggacgtggcg
cgcaagctgctgatcctggcgcgcgaagccggttacaagctggagctgagcgatatcgag
gtcgagccggtgctgccgccgtccttcgacgcgtcgggcgacgtggagcatttcctggcg
cggctgccggaactggataaagagttcgcgcgcaacgtggccaatgccgccgagcaaggc
aaggtgctgcgctatgtcggcctgatcgacgaagggcgctgtaaggtgcgcatcgaggcg
gtggacggcaacgatccgttgtataaagtgaagaacggcgagaacgcgctggccttctac
agccgttattatcagccgctgccgctggtgctgcgcggctacggcgccggtaacgatgtg
accgcagcgggcgtgttcgccgatctgctgcgcacactgtcatggaagttgggagtttaa
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