KEGG   Serratia sp. HRI: GF111_15040
Entry
GF111_15040       CDS       T10951                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
serh  Serratia sp. HRI
Pathway
serh00270  Cysteine and methionine metabolism
serh00450  Selenocompound metabolism
serh00670  One carbon pool by folate
serh01100  Metabolic pathways
serh01110  Biosynthesis of secondary metabolites
serh01230  Biosynthesis of amino acids
serh04981  Folate transport and metabolism
Module
serh_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:serh00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    GF111_15040 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    GF111_15040 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    GF111_15040 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    GF111_15040 (metH)
   04980 Cobalamin transport and metabolism
    GF111_15040 (metH)
Enzymes [BR:serh01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     GF111_15040 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: UBI62205
LinkDB
Position
3121243..3124938
AA seq 1231 aa
MEGVTVTNRVEQLRRQLAQRILVLDGGMGTMIQSYRLDERDFRGERFADWRSDLKGNNDL
LVLTKPEVITAIHYAYLEAGADILETNTFNSTSIAMADYHMESLSAEINYQAACLARACA
DEWTARTPEKPRYVAGVLGPTNRTASISPNVNDPAFRNISFDELVAAYRESTRALVEGGV
DLIMIETIFDTLNAKAAAFAVETEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSL
RHVKPLTFGLNCALGPDELRQYVAELARISETYVTAHPNAGLPNAFGEYDLDAAEMARQV
GEWAQAGFLNIIGGCCGTTPEHIAAMANAVEGVPPRRLPEIPVACRLAGLEPLTIDANTL
FVNVGERTNVTGSARFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVR
FLNLIAGEPDIARVPIMIDSSKWSVIEKGLKCIQGKGIVNSISMKEGEEAFIHHAKLVRR
YGAAVVVMAFDEVGQADTRERKFEICRRAYNILTERVGFPPEDIIFDPNIFAVATGIEEH
NNYAVDFIEACADIKTHLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYHAIRNGMDMG
IVNAGQLAIYDDLPTELREAVEDVILNRREDGTERLLELAEKYRGSKDNDVAVQQAEWRG
WPVEKRLEYSLVKGITEFIELDTEEARQQAERPIEVIEGPLMAGMNVVGDLFGEGKMFLP
QVVKSARVMKQAVAYLEPYIEASKQQGTSAGKILLATVKGDVHDIGKNIVGVVLQCNNYE
IVDLGVMVPTEKILRTAREENVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGAT
TSKAHTAVKIEQNYSGPTTYVQNASRTVGVVSALLSATQRDEFVARTRKEYETVRIQHAR
KKPRTPPVDLQKARANAMALDWADYQPPAPRQLGVFPVAAGIETLRHYIDWTPFFMTWSL
AGKYPRILEDEVVGEEAKRLFHDANQMLDRLAAERSLNPRGVYGLFPANRVGDDVEVYRD
ERRDEVLAVSRHLRQQTEKTDFPNYCLADFVAPKSSGKADYFGAFAVTGGLEEDALAAAF
DAQHDDYNKIMVKALADRLAEAFAEYLHEQVRKLHWGYAADESLSNEELIRENYQGIRPA
PGYPACPEHTEKATIWQLLDVNRHTGMELTESFAMWPGAAVSGWYFSHPESKYFAVAQIQ
RDQVEDYAVRKGMSVSEVERWLAPNLGYDAD
NT seq 3696 nt   +upstreamnt  +downstreamnt
atggaaggggttacagtgacgaatcgagtagaacaactgcgtcgccagttagcgcagcgc
attttggtgttggacggcggcatgggcaccatgatccagagctaccgtctggacgagcgt
gatttccgcggtgagcgtttcgccgactggcgcagcgatctgaaaggcaacaacgatctg
ctggtgctgaccaagccggaagtgatcaccgccattcattacgcctatcttgaggcgggc
gccgatatccttgagaccaataccttcaactccacctccatcgccatggccgactaccac
atggagtcgctgtccgccgagattaactatcaggccgcctgcctggcgcgcgcctgcgcc
gacgaatggacggcgcgcacgccggaaaaaccgcgctacgtcgccggggtgctggggccg
accaaccgcactgcgtccatctcgccgaacgtcaacgatccggcgttccgcaacatttcg
ttcgatgagctggtggcggcttaccgcgaatcgacccgcgcgctggtggagggcggcgtc
gatctgatcatgatcgaaaccatcttcgacaccctgaatgccaaggccgccgcttttgca
gtggaaaccgaattcgaagcgttgggggtggaactgccgatcatgatttccggcaccatc
accgacgcctccggccgtactttgtccggccagaccaccgaagcgttttacaattcgctg
cgccacgtcaagccgctgactttcggcctgaactgcgctctgggcccggacgaactgcgt
cagtacgtcgccgagctggcgcgcatctcggagacctacgtcaccgcgcacccgaacgcc
ggtttgccgaacgccttcggcgagtacgatctggatgcggccgagatggcgcgccaggtc
ggggagtgggcgcaggccggcttcctcaatatcatcggcggctgctgcggcaccacgccg
gaacatatcgccgcgatggccaacgcggtcgagggcgtgccaccgcgccggctgccggag
atcccggtcgcctgccgcctggcgggcctggagccgctgaccatcgatgccaacaccctg
ttcgtcaacgtcggcgagcgcaccaacgtcaccggttcggcgcgattcaaacgcctgatc
aaagaagagaaatacagcgaggcgctcgacgtggcgcgccagcaggtcgagagcggcgcg
cagatcatcgacatcaacatggacgaggggatgctcgacgccgaagcggcgatggtgcgc
ttccttaacctgattgccggcgagccggatatcgcccgagtgccgatcatgatcgactcc
tccaagtggtccgttatcgagaaaggcctgaagtgcattcagggcaagggcatcgtcaac
tcgatctcgatgaaggagggtgaggaagcctttatccaccacgccaaactggtgcgccgc
tacggtgccgcggtggtggtgatggcgttcgacgaagtggggcaggcggacacccgcgag
cgcaagttcgagatctgccgccgcgcctataacattctgaccgaacgcgtcggcttcccg
ccggaagacatcattttcgacccgaacattttcgctgtcgctacgggcattgaagagcac
aacaactacgccgtcgactttatcgaagcctgcgccgacatcaaaacccacctgccgcac
gcgatgatctccggcggcgtgtccaacgtgtcgttctcgttccgcggcaacgatccggtg
cgtgaagcgatccatgcggtgttcctgtatcacgccattcgcaacggcatggacatgggc
atcgtcaacgccgggcagctggcgatttatgacgatctgcctaccgagctgcgcgaggcg
gtagaggacgtgatcctcaaccgtcgcgaggacggcaccgaacgcctgctggagctggcc
gaaaaataccgcggcagcaaagataatgacgtggcggtgcagcaggctgaatggcgcggc
tggccggtagaaaaacggctggaatattcgctggtgaagggcatcaccgagtttatcgag
ctggacaccgaagaagcgcggcagcaggccgaacgcccgatcgaagtgatcgaagggccg
ctgatggcggggatgaacgtggttggcgatctgttcggcgagggcaagatgttcctgccg
caggtggtgaaatccgcccgcgtgatgaagcaggcggtggcctacctggaaccgtacatc
gaggccagcaagcagcagggcacctctgcggggaaaatcctgttggcgacggtgaagggc
gacgtgcatgacatcggcaagaacatcgtcggcgtggtgctgcagtgcaacaactatgaa
atcgtcgatctgggcgtgatggtgccgacggagaaaatcctgcgcaccgcgcgtgaggag
aacgtggacatcatcggcctgtcggggctgatcacgccgtcgctcgacgagatggtcaac
gtggcgaaagaaatggagcgccagggctttacgttgccgctgctgatcggcggcgccacc
acctccaaggcgcacaccgcggtgaaaatcgagcagaactacagcggcccgaccacctac
gtgcaaaacgcctcgcgcaccgtgggcgtagtgtcggcgctgctgtccgccacccagcgc
gacgagtttgtggcgcgcacccgcaaagagtatgaaacggtgcgcattcagcatgcgcgt
aaaaagccacgcacgccgccggtcgatttgcagaaggcacgcgccaacgccatggcgctg
gactgggccgattatcagccgccggcgccgcggcagctcggcgtgttcccggtggcggcc
ggtatcgagacgctgcgccactacatcgactggacgccgttcttcatgacctggtcgctg
gcgggcaaatacccgcgcatcctggaagacgaggtggtgggggaagaggccaagcgcctg
ttccacgacgccaatcagatgctggatcggctggccgccgagcgcagcctcaacccgcgc
ggcgtttacggcctgttcccggccaaccgcgtcggcgacgacgtggaagtataccgcgac
gaacggcgtgacgaggtgctggcggtgagccgccatctgcgtcagcagacggaaaaaacc
gacttcccgaactactgcctggcggacttcgtggcgccgaaaagcagcggcaaggccgac
tacttcggcgccttcgcggtgaccggcgggctggaggaggacgcgttggcggcggcgttc
gacgcgcagcacgacgattacaacaaaatcatggttaaggcgctggcggatcgcttggcg
gaggccttcgccgaatacctgcatgagcaggtgcgcaagctgcactggggctatgccgcc
gacgagagcctgagcaacgaagagctgatccgcgaaaactatcagggcatccggccggcg
ccgggttatccggcctgcccggagcacaccgagaaagcgaccatctggcagctgctggac
gtcaaccgccacaccggcatggagctgacggagtccttcgccatgtggccgggggcagcg
gtgtccggctggtacttcagccatcctgaaagcaagtacttcgcggtggcgcagatccag
cgcgatcaggtggaagactacgcggtgcgtaaagggatgagcgtgagcgaggtcgaacgg
tggctggcgcctaacctcggctacgacgccgactga

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