Serratia sp. SCBI: SERRSCBI_21535
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Entry
SERRSCBI_21535 CDS
T03314
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sers
Serratia sp. SCBI
Pathway
sers00270
Cysteine and methionine metabolism
sers00450
Selenocompound metabolism
sers00670
One carbon pool by folate
sers01100
Metabolic pathways
sers01110
Biosynthesis of secondary metabolites
sers01230
Biosynthesis of amino acids
Module
sers_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sers00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SERRSCBI_21535 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SERRSCBI_21535 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SERRSCBI_21535 (metH)
09150 Organismal Systems
09154 Digestive system
04980 Cobalamin transport and metabolism
SERRSCBI_21535 (metH)
Enzymes [BR:
sers01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SERRSCBI_21535 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
AIM23865
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All DBs
Position
complement(4621704..4625384)
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AA seq
1226 aa
AA seq
DB search
MTNRVEQLRRQLAQRILVLDGGMGTMIQSYRLDERDFRGERFADWRSDLKGNNDLLVLTK
PEVITAIHYAYLEAGADILETNTFNSTSIAMADYHMESLSAEINYQAACLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPNVNDPAFRNISFDELVAAYRESTRALVEGGVDLIMI
ETIFDTLNAKAAAFAVETEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHVKP
LTFGLNCALGPDELRQYVAELARISETYVTAHPNAGLPNAFGEYDLDAAEMARQVGEWAQ
AGFLNIIGGCCGTTPEHIAAMAKAVEGVPPRRLPDIPVACRLAGLEPLTIDANTLFVNVG
ERTNVTGSARFKRLIKEEKYNEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWSVIEKGLKCIQGKGIVNSISMKEGEEAFIHHARLVRRYGAAV
VVMAFDEVGQADTRERKFEICRRAYKILTERVGFPPEDIIFDPNIFAVATGIDEHNNYAV
DFIEACADIKTHLPHAMISGGVSNVSFSFRGNDPVREAIHAVFLYHAIRNGMDMGIVNAG
QLAIYDDLPGELREAVEDVILNRREDGTERLLELAEKYRGSKDGEAAVQQAEWRGWPVEK
RLEYSLVKGITEFIELDTEEARQQAERPIEVIEGPLMAGMNVVGDLFGEGKMFLPQVVKS
ARVMKQAVAYLEPYIEASKQQGTSAGKILLATVKGDVHDIGKNIVGVVLQCNNYEIVDLG
VMVPTEKILRTAREENVDIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKAH
TAVKIEQNYSGPTTYVQNASRTVGVVSALLSATQRDEFVARTRKEYETVRIQHARKKPRT
PPVDLHKARANAMALNWADYQPPAPRQLGVFPVSAGIETLRHYIDWTPFFMTWSLAGKYP
RILEDEVVGEEAKRLFHDANQMLDRLAAERSLNPRGVYGLFPANRVGDDVEVYRDERRDE
VLAVSRHLRQQTEKTDFPNYCLADFVAPKSSGKADYFGAFAVTGGLEEDALAAAYDAQHD
DYNKIMVKALADRLAEAFAEYLHEQVRKLHWGYAADESLSNEELIRENYQGIRPAPGYPA
CPEHTEKATIWQLLDVNRHTGMELTESFAMWPGAAVSGWYFSHPESKYFAVAQIQRDQVE
DYAARKGMSVSEVERWLAPNLGYDAD
NT seq
3681 nt
NT seq
+upstream
nt +downstream
nt
gtgacgaatcgagtagaacaactgcgccgccagttagcgcagcgcattttggtgttggac
ggcggcatgggcaccatgatccagagctaccgtctggatgagcgcgatttccgcggtgag
cgtttcgccgactggcgcagcgatctgaaaggcaacaacgatctgctggtgctgaccaag
ccggaagtgatcaccgccattcattacgcctatctcgaggcgggcgccgatatccttgag
accaataccttcaactccacctccatcgccatggccgactaccatatggagtcgctgtcc
gccgagattaactatcaggccgcctgcctggcgcgcgcctgcgccgacgaatggacggcg
cgcacgccggaaaaaccgcgctacgtcgccggggtgttggggccgaccaaccgcaccgcg
tccatctcgccgaacgtcaacgatccggcgttccgcaacatctcgttcgatgaactggtg
gcggcttaccgcgaatcgacccgcgcgctggtggaaggcggcgtcgatctgatcatgatc
gaaaccatcttcgacaccctcaacgccaaggccgccgcttttgcggtggaaaccgaattc
gaagcgctgggggtggaactgccgatcatgatttccggcaccatcaccgacgcttccggc
cgcaccctgtccggccagaccaccgaagcgttttacaattcgctgcgccacgtcaagccg
ctgaccttcggcctgaactgcgccctggggccggatgagctgcgtcagtacgtcgcggag
ctggcgcgcatctcggagacctacgtcaccgcacacccgaacgccggtttgccgaacgcc
ttcggcgagtacgatctggatgcggccgagatggcgcgccaggtcggggagtgggcgcag
gccggctttctcaatattatcggcggctgctgcggcaccacgccggaacatatcgccgcg
atggccaaggcggtcgagggcgtgccgccgcgccggctgccggatatcccggtcgcctgc
cgcctggccggtctggagccgttgaccatcgacgccaacaccctgttcgtcaacgtcggc
gagcgcaccaacgtcaccggttcggcgcgtttcaaacgcttgatcaaagaagagaaatac
aacgaggcgctcgacgtggcgcgtcagcaggtcgagaacggcgcgcagatcatcgacatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgcttcctcaacctgatc
gccggcgagccggatatcgcccgggtgccgatcatgatcgactcctccaagtggtccgtt
atcgagaaaggcctgaagtgcattcagggcaagggtatcgtcaactcgatctcgatgaag
gagggcgaagaggcctttatccaccacgccaggctggtgcgccgctatggcgccgcggtg
gtggtgatggcgttcgacgaagtgggccaggcggacacccgcgagcgcaagttcgagatc
tgtcgccgcgcctataaaattttgaccgaacgcgtcggtttcccgccggaagacatcatt
ttcgacccgaacatcttcgccgtcgccaccggcatcgacgagcacaacaactacgccgtc
gactttatcgaagcctgcgccgacatcaaaacccacctgccgcacgcgatgatctccggc
ggggtgtccaacgtgtcgttctcgttccgcggcaacgatccggtgcgtgaagcgatccac
gcggtattcctgtatcacgccattcgcaacggcatggacatgggcatcgtcaacgccggg
cagctggcgatttacgacgatctgcctggcgagctgcgcgaggcggtagaagacgtgatc
ctcaaccgtcgcgaggacggcaccgaacgcttgctggaactggcggaaaagtaccgcggc
agcaaagacggcgaagcggcggtgcagcaggcggaatggcgcggctggccggtggagaag
cggctggaatactcgctggtgaagggcatcaccgagtttatcgaactggacaccgaagaa
gcgcggcagcaggccgaacgtccgatcgaagtgatcgaagggccgctgatggccgggatg
aacgtggtcggcgatctgttcggcgagggcaagatgttcctgccgcaggtggtgaaatcc
gcccgcgtgatgaagcaagcggtggcctacctggaaccgtacatcgaggccagcaagcag
cagggcacctccgcgggcaaaatcctgttggcgacggtgaaaggcgacgtgcacgacatc
ggcaagaacatcgtcggcgtggtgctgcagtgcaacaactatgaaatcgtcgatcttggc
gtgatggtgccgacggagaaaatcctgcgcaccgcgcgcgaggagaatgtcgacatcatc
ggcctgtcggggctgatcacgccgtcgctcgacgagatggtcaacgtggccaaagagatg
gagcgccagggctttacgctgccgctgctgatcggcggcgccaccacctccaaggcgcac
accgcggtgaaaatcgagcagaactacagcggcccgaccacctacgtgcaaaacgcctcg
cgcaccgtgggcgtggtgtcggcgctgctgtccgccacccagcgcgacgagttcgtggcg
cgcacccgcaaagagtatgaaacggtgcgcattcaacacgcgcgcaaaaagccgcgcacg
ccgccggtcgatttgcacaaggcgcgcgccaacgccatggcgctgaactgggccgactat
cagccgccggcgccgcggcagcttggcgtgtttccggtgtcggccggcatcgagacgctg
cgccactatatcgactggacgccgttcttcatgacctggtcgctggcgggcaaataccca
cgcatcctcgaggatgaggtggtgggggaagaggccaagcgcctgttccatgacgccaat
cagatgctggatcggttggccgccgagcgcagcctcaacccgcgcggcgtttacggcctg
ttcccggccaaccgcgtcggcgacgacgtggaggtataccgcgacgaacggcgtgacgag
gtgctggcggtgagtcgccacctgcggcaacagacggaaaaaaccgacttcccgaactac
tgcctggcggactttgtggcgccgaaaagcagcggcaaagccgactacttcggcgccttc
gcggtgaccggcgggctggaggaagacgcgctggcggcggcgtacgacgcgcagcacgac
gattacaacaaaatcatggtcaaggcgctggcggatcgtttggcggaggcttttgccgaa
tacctgcacgaacaggtgcgcaagctgcactggggctatgccgccgacgagagcctgagc
aacgaggagctgatccgggaaaactatcagggcatccggccggcgccgggctacccggcc
tgcccggagcacaccgaaaaagcgaccatctggcagctgttggacgtcaaccgccacacc
ggtatggaactgacggagtccttcgccatgtggccgggggcggcggtatccggctggtac
ttcagccaccccgagagcaagtacttcgcggtggcgcagatccagcgcgatcaggtggaa
gactacgcggcgcgtaaagggatgagcgtgagcgaggtcgagcgctggctggcgccaaac
ctcggctacgacgccgactga
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