Suncus etruscus (white-toothed pygmy shrew): 126001122
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Entry
126001122 CDS
T09902
Symbol
IRS1
Name
(RefSeq) insulin receptor substrate 1
KO
K16172
insulin receptor substrate 1
Organism
setr
Suncus etruscus (white-toothed pygmy shrew)
Pathway
setr04022
cGMP-PKG signaling pathway
setr04068
FoxO signaling pathway
setr04081
Hormone signaling
setr04140
Autophagy - animal
setr04150
mTOR signaling pathway
setr04151
PI3K-Akt signaling pathway
setr04152
AMPK signaling pathway
setr04211
Longevity regulating pathway
setr04213
Longevity regulating pathway - multiple species
setr04722
Neurotrophin signaling pathway
setr04910
Insulin signaling pathway
setr04920
Adipocytokine signaling pathway
setr04923
Regulation of lipolysis in adipocytes
setr04930
Type II diabetes mellitus
setr04931
Insulin resistance
setr04932
Non-alcoholic fatty liver disease
setr04935
Growth hormone synthesis, secretion and action
setr04960
Aldosterone-regulated sodium reabsorption
setr05010
Alzheimer disease
setr05206
MicroRNAs in cancer
setr05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
setr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
126001122 (IRS1)
04022 cGMP-PKG signaling pathway
126001122 (IRS1)
04151 PI3K-Akt signaling pathway
126001122 (IRS1)
04152 AMPK signaling pathway
126001122 (IRS1)
04150 mTOR signaling pathway
126001122 (IRS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
126001122 (IRS1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
126001122 (IRS1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
126001122 (IRS1)
04923 Regulation of lipolysis in adipocytes
126001122 (IRS1)
04920 Adipocytokine signaling pathway
126001122 (IRS1)
04935 Growth hormone synthesis, secretion and action
126001122 (IRS1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
126001122 (IRS1)
09156 Nervous system
04722 Neurotrophin signaling pathway
126001122 (IRS1)
09149 Aging
04211 Longevity regulating pathway
126001122 (IRS1)
04213 Longevity regulating pathway - multiple species
126001122 (IRS1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
126001122 (IRS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
126001122 (IRS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
126001122 (IRS1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
126001122 (IRS1)
04932 Non-alcoholic fatty liver disease
126001122 (IRS1)
04931 Insulin resistance
126001122 (IRS1)
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Motif
Pfam:
IRS
PH
PH_11
Motif
Other DBs
NCBI-GeneID:
126001122
NCBI-ProteinID:
XP_049624259
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Position
2:23667635..23732307
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AA seq
1265 aa
AA seq
DB search
MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP
KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH
HHHDGGGGGGGGGAAGPGGAGGAGGGSCSGSSGLGEAGEDLSYGEMPPGPAFKEVWQVIL
KPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRS
AVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHH
LNNPPPSQVGLTRRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVS
PSTNRTHAHRHRGNSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLF
PRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICM
GGKGPSTLAAPNGHYILPRAGNGHRYIPGAGGAGLGLSPALATEDSGASDLDNRFRKRTH
SAGTSPTISHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRPPGYRHSAFVPTHSYPEET
LEMHPLERHGGHPRPDPSAHHRPDDGYMPMSPGVAPTPTSRKGSGGDYMPMSPKSVSAPQ
QIINPIRRHPQRVDPNGYMMMSPSGSCSPDISGGPSGGSSSATPSGGSYGKLWTNGVGGH
PSPALPHPKLPVGSSSGGKLLSSCAGDYMNMSPVADSTTNSPSDSYYVQEEPQHKPVLSY
CSLPRSFKHTQRPGELEETVRHQHLRLSASSGRLVYTAAPVPEDSSSSTSSDSLGSGYCG
VRPEPGLPHLHHQVLQPYLPRKVDTAAQTHSRLTRPTRLSLGDPKASTLPRAREQQQLPP
QPPLLHPPEPKSPGEYVNIEFGGDPPGYLSGPVASHSPPSVCCPVPLQPAPREEETGTEE
YMNMDLGPRRAGWQESSGVSVGRVGPASLGTSNMCRPIRAVPSSRGDYMTMQVTCPRPSY
VDTSPVAPISYADMRTGVVVEEVSLPGDTADAPSSSSASTSPTGPSTGVGELAGHSSLLG
ASQGPGAMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRAGNSVPFAG
GPALGGGNGGCSSSSSNSNSEEVKRHSSASFENVWLRPGELGAVAKEPTQVCGAPGGLEN
GLNYIDLDLVKDFKQRPPERPPQPQPPPPPAPHQPLGSSQSSRRSSEDLSAYASISFQKQ
LEDRQ
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atggcgagccccccggagaccgacggcttctcggacgtgcgcaaggtgggctacctgcgc
aagcccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc
cccgcgcgcctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc
aaacgctcgatccccctggagagctgcttcaacatcaacaagcgggccgactccaagaac
aagcacctggtggccctctacacccgagacgagcactttgccatcgcggccgacagcgag
gcggagcaggacagctggtaccaggccctcctgcagctgcacaaccgtgccaagggccac
caccaccacgacggcggcggcggcggcggtggcggcggcgctgcgggcccgggcggcgct
gggggagccggcgggggcagctgcagcggcagctccggcctaggggaggccggcgaggac
ttgagttacggggagatgcctccaggacccgcgttcaaggaggtctggcaggtgatcctg
aagcccaagggcttggggcagacaaagaacctgattggcatctaccgcctttgcctcacc
agcaagaccatcagcttcgtgaagctcaactcggaggctgcggctgtggtgctgcagctc
atgaacatccgacgctgcggccactcggagaacttcttcttcatcgaggtgggccgctcg
gccgtgacgggccccggggagttctggatgcaggtggatgactcggtggtggcgcagaac
atgcacgagaccatcctggaggccatgcgggccatgagcgacgagttcaggccgcgcagc
aaaagccagtcgtcgtccaactgctccaaccccattagcgtccccctgcgccggcaccac
ctcaacaacccgccgcccagccaggtaggcctgacccgtcgctcacgcaccgagagcatc
accgccacgtccccggccagcttggtgggcggcaagcagggctctttccgcgtccgagcc
tccagcgacggtgaaggcaccatgtccaggcctgcctcggtggacggcagccccgtgagc
cccagcaccaatcggacccacgcgcaccggcatcggggcaactccaggctgcaccccccg
ctcaaccacagccgctccatccccatgccgtcctcacgctgctcgccctctgccaccagc
cccgttagcctgtcgtccagcagcactagtggccacggctccacgtcggactgtctcttc
ccgcgtcgctccagtgcctcggtgtccggctcgcccagcgacggcggcttcatctcctcc
gatgagtacggttccagcccttgcgatttccgcagctccttccgcagcgtcaccccagac
tccctgggccacaccccacccgcccgtggagaggaggagctgagcaattacatctgcatg
ggaggcaaagggccttccaccctcgccgcccccaacggacactatattctgccccgggcg
ggcaatggacatcgctacatccccggtgcgggaggagccggcctgggcttgagcccggcc
ctggccacggaggattcgggtgccagcgatctggacaatcgcttccgcaagcggacccac
tcggcgggcacctcgcccaccatttcccatcagaagaccccctcgcagtcctcggtggca
tccatcgaggaatacacggagatgatgcccgcctacccaccaggagggggcagtggaggc
cggcctcccggctaccggcattcggccttcgtgcccacccactcttaccccgaggaaacc
ctggaaatgcatcccttggagcgccatggaggccacccgcgccccgatccctctgcccat
caccgcccggatgatggctacatgcccatgtctcctggcgtggcccccacgcccaccagc
cgcaagggcagtggcggtgactacatgcctatgagccccaagagcgtgtcggcccctcag
cagatcatcaaccccatccggcgccatccgcagcgagtagaccccaatggctacatgatg
atgtcgcccagtggcagctgctctcctgacatctccgggggccccagcggtggcagcagc
agtgccaccccttcagggggtagctatggcaaattatggacgaatggggtgggaggccac
ccttcccccgccctgccgcatcccaagctacccgtggggagcagcagcgggggcaagctc
ctgtcgtcgtgcgccggagactacatgaacatgtcccctgtggcggactccaccaccaac
agcccttccgacagctactacgttcaggaggaaccccagcataagccggtcctgtcctac
tgctccttgcccaggtcctttaagcacacccagcgccccggggagctggaggagacagtc
cgacaccagcacctccgcctctccgccagctctggccgcctggtctacaccgcggcccct
gtgcccgaagattcctcctcctccaccagcagtgacagcctgggtagcgggtactgtggg
gtaaggccggagcctggcctccctcatctccatcaccaggtcctgcagccctacctgccc
cggaaggtggacacagccgcccagacccacagccgcctgacaaggcccacacggctgtct
ctgggggaccccaaggccagcaccttgccgcgggcccgagaacaacagcaattgccccct
cagccccctctgctgcaccctcccgagcctaagagccctggggaatatgtgaatattgaa
tttgggggtgacccacctggctacctatcgggacccgtggcttcgcacagccctccttct
gtctgctgcccagtcccgttgcagcccgcaccgcgggaggaagagacgggcacagaagag
tacatgaacatggacttggggccccggagggcaggctggcaagagagctctggtgtttca
gtgggcagggtggggccggcctctttgggtacctcgaacatgtgcaggcccatccgggct
gtgcctagtagccggggtgactacatgaccatgcaggtgacttgtccccggccaagctat
gtagacacctctcctgtagcccccatcagctatgctgatatgcggacaggggtcgtggtg
gaggaggtgagccttcctggggacacagcggatgctccatcctcatcttctgcctctact
tcccccactgggccttctacaggagttggggagctggctgggcactcttccctgctaggg
gcctcccaaggacctggagctatgagcgccttcacccgggtcaacctcagtcccaaccgc
aaccagagtgccaaagtgatccgggcggacccacaggggtgccgaaggcggcacagctcc
gagaccttctcctctacgcctagtgccacccgggcaggcaactcggtgccctttgcaggg
ggtcctgccctagggggtggcaacggaggctgcagtagcagcagcagcaacagcaacagc
gaggaggtgaagcgccacagctctgcttcctttgagaatgtgtggctcaggcctggggag
cttggggcagtcgccaaggaacctactcaagtgtgtggggctcctgggggtctggagaat
ggtctgaactacatagacctggacttggtcaaggatttcaaacagcgccccccagagcgc
ccgcctcaaccacagcctcccccacccccagcccctcatcagcctttgggcagcagccag
agcagccgccgctccagtgaggatttaagcgcctatgccagcatcagtttccagaagcag
ctagaggaccgccagtag
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