Salmonella enterica subsp. enterica serovar Schwarzengrund: SeSA_A4401
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Entry
SeSA_A4401 CDS
T00743
Symbol
metH
Name
(GenBank) methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sew
Salmonella enterica subsp. enterica serovar Schwarzengrund
Pathway
sew00270
Cysteine and methionine metabolism
sew00450
Selenocompound metabolism
sew00670
One carbon pool by folate
sew01100
Metabolic pathways
sew01110
Biosynthesis of secondary metabolites
sew01230
Biosynthesis of amino acids
sew04981
Folate transport and metabolism
Module
sew_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sew00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SeSA_A4401 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SeSA_A4401 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SeSA_A4401 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SeSA_A4401 (metH)
04980 Cobalamin transport and metabolism
SeSA_A4401 (metH)
Enzymes [BR:
sew01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SeSA_A4401 (metH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
ACF91885
UniProt:
A0A0N1QYY5
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All DBs
Position
4274314..4277997
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AA seq
1227 aa
AA seq
DB search
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA
RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGVDLILI
ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLPPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQASRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAYEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
TDYAFRKGMSVENVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcaccatgatccagagctatcgtctacatgaagaagatttccgcggggag
cgctttgccgactggccctgcgacctgaaaggcaacaatgacctgctggtactcagcaag
ccggaggtgatcgccgctatccacaacgcctactttgaggctggcgcggatatcatcgaa
accaacacctttaactcgacaaccattgcgatggcggattaccggatggaatccctgtcg
gcggaaattaactatgcggcggccaaactggcgcgcgcctgcgccgatgaatggacggcg
cgaacaccagaaaaaccacgctttgttgcgggcgtgcttggtccaactaaccgcacggcc
tccatttcgccggacgtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtg
gcggcctaccgtgaatccaccaaagcgctggtggaaggtggcgtagatctgattctgatt
gagaccgtctttgacaccctgaatgcgaaagcggcggtgtttgcggtgaaagaagagttt
gaagcgctgggcgttgatctgccgatcatgatttccggcaccatcaccgacgcctctggt
cgcaccctctccggccagactaccgaagccttttataactcgctgcgccacgccgaggcg
ctcacttttggccttaactgcgcgctggggccagatgaactgcgccagtacgtccaggaa
ctgtcgcggattgccgaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgct
ttcggcgagtacgacctcgacgccgacaccatggcgaaacagattcgcgaatgggcggag
gcgggcttcctgaatatcgttggcggctgctgcggcaccacgccggagcatattgcggcg
atgagccgcgccgttgccggtttgccgccgcgccagctgccggatatcccggttgcctgc
cgcctttccggcctggagccgctgaacattggcgacgacagcctgtttgtcaacgtcggc
gaacgtactaacgtcaccggctcggccaaatttaaacggctgatcaaagaagagaaatac
agcgaagcgctggatgtcgcccgtcagcaggtcgaaagcggcgcgcagattattgatatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatt
gccggtgagccggatattgcccgtgtaccaatcatgatcgactcctccaaatgggaggtt
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaa
gagggcgtggaagcttttattcatcatgcgaagttgctacgtcgctacggcgcggcagtg
gtggtgatggcctttgatgagcaggggcaggccgatacccgcgagcgtaaaatcgagatt
tgccgccgggcgtacaaaattctcaccgaagaggtgggcttcccgccggaagacatcatc
ttcgacccgaatatcttcgccgtggcgaccggtattgaagagcacaacaactatgcgcag
gactttatcggcgcttgcgaagatattaaacgcgagctgccgcatgcgctgatctccggc
ggcgtgtctaacgtgtccttctcgttccgcggcaacgacccggtacgtgaggctatccac
gcggtattcctctactacgccatccgcaacggcatggacatgggcatcgtcaacgccggg
caattggcgatttatgacgacctgcctgccgaactgcgcgatgcggttgaagatgtcatt
cttaaccgtcgcgatgacggcactgagcgtttgctggatttggcggagaaataccgcggc
agcaaaaccgacgaagctgccaacgcccagcaggcggaatggcgtagctgggacgtgaaa
aagcgtctcgaatactcgctggtgaaaggcattaccgaatttatcgaacaggataccgaa
gaagcccgccagcaggcctcccgcccgattgaggtgatcgaagggccgctgatggacggc
atgaacgtggtcggcgacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaa
tccgctcgcgtgatgaaacaagcggtggcttacctggagccgtttattgaagccagcaaa
gaaaaaggctccagcaacggcaagatggtcatcgccaccgtgaagggcgatgtgcacgac
attggcaagaacattgttggcgtggtgctgcaatgcaacaactacgaaatcgtcgatctt
ggcgtgatggtgccagcggagaaaatcctcagaacggcgcgtgaagtgaatgccgatctg
atcggtctttccgggcttatcaccccgtcgctggacgagatggtcaacgtggcgaaagag
atggagcgtcagggctttactatcccgctactgatcggcggcgcaaccacttcgaaagcg
cacaccgcggtgaaaatcgagcagaactacagcggtccgacggtctacgtgcagaatgct
tcgcgtaccgtgggcgtggtggcggcgctactctccgacacccagcgcgatgactttgtc
gcccgtacccgcaaagagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgc
acgccgccggtcacgctggaagcggcgcgcgataacgatctggcattcgattgggaacgc
tacaccccgccagtagcccaccgtctgggcgtgcaggaggtagaagccagcatcgaaacg
ctgcgcaactacatcgactggacgccgttctttatgacctggtcgctggccggcaaatac
ccgcgtattctggaagatgaagtggtgggcgttgaggcgcagcgcctgtttaaagacgcc
aacgacatgctggataaactgagcgcggagaaactgttgaatccgcgtggcgtggtgggc
ttgttcccggcgaaccgtgtgggtgacgacatcgaaatctatcgcgacgaaacccgtact
catgttctgacggtcagccaccacctgcgccagcagactgagaaagtcggttttgccaac
tactgtctggcggattttgtcgcgccgaaattgtccggaaaagcggactacatcggcgcg
tttgccgtcaccggcggtcttgaagaagacgccctggctgatgcttacgaagcgcaacac
gacgactataacaagatcatggtgaaagcgattgccgaccgtctggcggaagcgtttgcc
gagtacctgcatgagcgtgtacgtaaggtttactggggatatgcgccgaacgagagcctg
agtaacgacgaattaatccgcgaaaactaccaggggattcgcccggcgccgggttatcct
gcctgcccggaacataccgaaaaaggcactatctggcagctactggatgtcgaaaaacac
accgggatgaagctcaccgaatctttcgccatgtggcctggcgcgtcggtctccggctgg
tacttcagccatcctgagagcaaatacttcgcggtagcgcagattcaacgcgatcaggtg
acagattatgctttccgtaaaggaatgagcgttgagaacgttgagcggtggctggcgccg
aacctgggttacgatgcggactga
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