Streptomyces explomaris: SLV14_002525
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Entry
SLV14_002525 CDS
T11122
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sexp Streptomyces explomaris
Pathway
sexp00020
Citrate cycle (TCA cycle)
sexp00630
Glyoxylate and dicarboxylate metabolism
sexp00785
Lipoic acid metabolism
sexp01100
Metabolic pathways
sexp01110
Biosynthesis of secondary metabolites
sexp01120
Microbial metabolism in diverse environments
sexp01200
Carbon metabolism
sexp01210
2-Oxocarboxylic acid metabolism
Module
sexp_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sexp_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sexp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SLV14_002525
00630 Glyoxylate and dicarboxylate metabolism
SLV14_002525
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SLV14_002525
Enzymes [BR:
sexp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SLV14_002525
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SLV14_002525
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SLV14_002525
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SLV14_002525
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GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
UYB39966
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Position
2980944..2984738
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AA seq
1264 aa
AA seq
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MSLQSPNSSSISTDHEGQGKNPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GGATAPSQPAEGPGASTGSAAAPAQASAPAAEPKPASAEPATPAKPAASAPAPAKAAPAK
APAKAAPAKPAAKPAAEEGQAPGGPEFIPLRGPSAAVAKNMNASLELPTATSVRAVPVKL
LFDNRIVINNHLKRARGGKVSFTHLIGYAMVQALKAMPSMNYSFAEKDGKPTLVKPEHVN
LGLAIDLVKPNGDRQLVVAAIKKAETLTFFEFWQAYEDIVRRARDNKLTMDDFTGVTASL
TNPGGIGTVHSVPRLMPGQSMIMGVGAMDYPAEFQGTSQDALNKLGVSKVMTLTSTYDHR
VIQGAASGEFLRIMSQLLLGENEFFDDIFKSLRIPYEPVRWLRDIDVSHDDDVTKAARVF
ELIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFSGKSMMKLRE
ILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERSHKSPEREEQLRILRRLNSAEAFET
FLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSY
AQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHLEAVDPIVEG
ISRAKQDIINKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQ
VGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDL
ICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQ
LEKVFTEVRDATTAPVAPEVPQPKAEFPVFVDTAISQEVVKRIAESQVNIPERVTVHPRL
LPQLQRRAAQVEDNAIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQRHAVLIDRET
GDDYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPEALVMWEAQFGDFVNGAQT
VVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAAPTLPS
NYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASRTDEFTTGGFRPVIGDSTVKPEDVRK
VIFCSGKVYYDLEAEREKRGAHDTAIVRIERLYPLPGKELQAEIAKFSNAEKYLWTQEEP
ANQGAWPFLGLNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQAQLVAE
AFDA
NT seq
3795 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacagctcgagcatctcgaccgaccacgaggggcaggggaag
aaccctgctgccgcgttcggtcccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggcggtgccaccgcgccgagccagccggcggagggccccggtgcgagcaccggctccgcg
gccgccccggcgcaggcgtccgcgcccgcagcggagccgaagccggcctccgccgagccg
gccaccccggcgaagccggctgcgagcgctccggcaccggccaaggccgctccggccaag
gctccggcgaaggcggctccggccaagcccgccgcgaagccggccgccgaggagggccag
gcccccggcggtcccgagttcatccccctgcgcggcccctcggccgcggtggcgaagaac
atgaacgcctccctggagctgccgacggccacgtccgtccgcgcggtcccggtgaagctg
ctcttcgacaaccgcatcgtgatcaacaaccacctcaagcgcgcccgcggtgggaaggtc
tccttcacccacctcatcgggtacgcgatggtgcaggccctcaaggccatgccgtcgatg
aactactccttcgcggagaaggacggcaagccgacgctggtcaagcccgagcacgtcaac
ctcggtctggccatcgacctggtgaagccgaacggcgaccgccagctcgtcgtcgccgcc
atcaagaaggccgagacgctgaccttcttcgagttctggcaggcctacgaggacatcgtc
cgccgggcccgtgacaacaagctgacgatggacgacttcaccggagtcaccgcgtcgctg
acgaaccccggcggcatcggcaccgtccactccgtgccgcgtctgatgcccggccagtcc
atgatcatgggcgtcggcgcgatggactaccccgcggagttccagggcacctcccaggac
gccctgaacaagctgggtgtctccaaggtcatgacgctgaccagcacctatgaccaccgg
gtgatccagggcgccgcctccggcgagttcctgcgcatcatgagccagctgctgctcggc
gagaacgaattcttcgacgacatcttcaagtcgctgcggattccctacgagcccgtccgc
tggctgcgggacatcgacgtctcccacgacgacgatgtcaccaaggccgcccgggtcttc
gagctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctggag
taccaccagcgcaagcaccccgacctcgacatcaccgagcacggcctcaccctgtgggac
ctggagcgcgagttcgcggtcggcggcttctccggcaagtccatgatgaagctgcgcgag
atcctgggcgtgctgcgtgactcgtactgccgcaccaccggcatcgagttcatgcacatc
caggaccccaagcagcgcaagtggatccaggaccgggtcgagcgctcgcacaagtcgccc
gagcgcgaggagcagctgcgcatcctgcgccggctgaactccgccgaggcgttcgagacg
ttcctgcagaccaagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtc
atcccgctgctggacgcggtcatcgactccgcggccgagtcgcgcctcgacgaggtcgtc
atcggcatggcccaccgcggccgcctcaacgtcctggcgaacatcgtcggcaagtcgtac
gcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggc
gatgtgaagtaccacctgggcgccgagggcaccttcaccggcctggacggcgagcagatc
aaggtctcgctggccgccaacccctcccacctggaggccgtcgacccgatcgtcgagggc
atctcgcgggccaagcaggacatcatcaacaagggcggcacggacttcacggtcctgccg
atccagctgcacggtgacgcggcgttcgccggccagggcgtggtcgcggagacgctgaac
atgtcccagctgcgcggctaccgcaccggcggcacggtgcacgtggtcatcaacaaccag
gtcggcttcaccgcagcgccggagtcgtcgcgttcgtccatgtacgccaccgacgtggcc
cgcatgatcgaggcgccgatcttccatgtgaacggtgacgaccccgaggccgtcgtccgc
gtggcccgtctggccttcgagttccgccaggcgttcaacaaggacgtggtcatcgacctg
atctgctaccgccgtcgcggccacaacgagtcggacaacccggccttcacccagccgctg
atgtacgacctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctcatc
ggtcgtggcgacatcacgctggaggaggccgagcaggcgctgcaggacttccagggccag
ctggagaaggtcttcaccgaggtccgcgacgccacgacggccccggtggcccccgaggtg
ccgcagcccaaggccgagttcccggtcttcgtggacaccgcgatctcccaggaggtcgtc
aagcggatcgccgagtcccaggtcaacatccccgagcgggtcaccgtccacccgcgtctg
ctgccccagctgcagcgccgcgcggcccaggtcgaggacaacgccatcgactggggcatg
ggcgagaccctcgccatcggctcgctgctgatggagggaaccccggtccggctcgccggc
caggactcccgccgtggcaccttcggccagcggcacgcggtgctcatcgaccgggagacc
ggcgacgactacacgccgctgctctacctctccgaggaccaggcccgcttcaacgtctac
gactcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactccctggcccgc
ccggaggcgctggtcatgtgggaggcgcagttcggtgacttcgtcaacggcgcccagacg
gtcgtcgacgagttcatctcctcggcggagcagaagtggggccagacgtccggcgtcacc
ctgctgctcccgcacggctacgagggccagggcccggaccactcctcggcccgcatcgag
cggttcctccagctgtgcgcgcagaacaacatgacggtcgccgcgccgaccctgccgtcg
aactacttccacctgctgcgctggcaggtccacaacccgcaccacaagccgctggtcgtc
ttcaccccgaagtcgatgctgcgtctgaaggcggcggcgtcgcggacggacgagttcacg
acgggcggtttccgccccgtcatcggcgactccacggtcaagcccgaggatgtccgcaag
gtcatcttctgctccggcaaggtctactacgacctggaggccgagcgcgagaagcgtggc
gcgcacgacaccgcgatcgtccgcatcgagcgcctctacccgcttcccggcaaggaactg
caggcggagatcgccaagttctcgaacgccgagaagtacctgtggacccaggaagaaccg
gcgaaccagggtgcctggccgttcctcggcctcaacctgatcgaccacctcgacctggcc
gtcggcgccgatgtcccgcacggtgagcggctgcgccggatctcccggccgcactcctcg
tcgccggccgtcggctccgccaagcgccaccaggcggagcaggcacagctggtcgcggag
gccttcgacgcataa
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