Salmonella enterica subsp. enterica serovar Typhimurium SL1344: SL1344_4123
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Entry
SL1344_4123 CDS
T01724
Symbol
metH
Name
(GenBank) B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
sey
Salmonella enterica subsp. enterica serovar Typhimurium SL1344
Pathway
sey00270
Cysteine and methionine metabolism
sey00450
Selenocompound metabolism
sey00670
One carbon pool by folate
sey01100
Metabolic pathways
sey01110
Biosynthesis of secondary metabolites
sey01230
Biosynthesis of amino acids
sey04981
Folate transport and metabolism
Module
sey_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
sey00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SL1344_4123 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
SL1344_4123 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
SL1344_4123 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
SL1344_4123 (metH)
04980 Cobalamin transport and metabolism
SL1344_4123 (metH)
Enzymes [BR:
sey01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
SL1344_4123 (metH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
CBW20211
UniProt:
A0A0H3NP26
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All DBs
Position
4429628..4433311
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AA seq
1227 aa
AA seq
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MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK
PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA
RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI
ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE
AGFLNIVGGCCGTTPEHIAAMSRAVAGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI
AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL
GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPR
TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT
HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH
DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP
ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
TDYAFRKGMSVEDVERWLAPNLGYDAD
NT seq
3684 nt
NT seq
+upstream
nt +downstream
nt
gtgagcagcaaagttgaacaactgcgtgcgcagttaaatgaacgtattctggtgctggac
ggcggtatgggcactatgatccagagctatcgtctacatgaagaagatttccgcggggag
cgctttgccgactggccctgcgacctgaaaggcaacaatgacctgctggtcctcagcaag
ccggaggtgatcgccgctatccacaacgcctactttgaggctggcgcggatatcatcgaa
accaacacctttaactcgacaaccattgcgatggcggattaccggatggaatccctgtcg
gcggaaattaactatgcggcggccaaactggcgcgcgcctgcgccgatgaatggacggcg
cgaacaccagaaaaaccacgctttgttgcgggcgtgcttggtccaactaaccgcacggcc
tccatttcgccggacgtcaacgacccggcgtttcgtaatatcaccttcgatcagctggtg
gcggcctaccgtgaatccaccaaagcgctggtggaaggtggcgcagatctgattctgatt
gagaccgtttttgacaccctgaatgcgaaagcggcggtgtttgcggtgaaagaagagttt
gaagcgctgggcgttgacctgccgatcatgatttccggcaccatcaccgacgcctctggc
cgtacgctttccggccagactaccgaagccttttataactcgctgcgccacgccgaggcg
ctcacttttggccttaactgcgcactggggccagatgaactgcgccagtacgtccaggaa
ctgtcgcggattgccgaatgctacgtcaccgcgcacccgaacgccggcctgccgaacgct
ttcggcgagtatgacctcgacgccgacaccatggcgaaacagattcgcgaatgggcggaa
gcgggcttcctgaatatcgttggcggctgctgcggcaccacgccggagcatattgcggcg
atgagccgcgccgttgccggtttgctgccgcgccagctgccggatatcccggtcgcctgc
cgcctttccggcctggagccgctgaacattggcgacgatagcctgtttgtgaacgtcggc
gaacgtactaacgtcaccggctcggccaaatttaaacggctgatcaaagaagagaaatac
agcgaagcgctggatgtcgcccgtcagcaggtagaaagcggcgcgcagattattgatatc
aatatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcagcctgatt
gccggtgagccggacattgcccgtgtaccaatcatgatcgactcctccaaatgggaggtt
atcgaaaaagggctgaagtgcattcagggtaaaggcatcgtcaactctatttcgatgaaa
gagggcgtggaagcctttattcatcatgcgaagcttctgcgtcgctacggcgcggcagtg
gtggtgatggcctttgatgagcaggggcaggccgatacccgcgcgcgtaaaatcgaaatt
tgccgccgagcctacaaaattctcaccgaagaggtgggtttcccgccggaagacatcatc
ttcgacccgaatatcttcgccgtggcgaccggtattgaagagcacaacaactacgcgcag
gactttatcggcgcttgcgaagacatcaaacgcgagctgccgcacgcgctgatctccggc
ggcgtgtctaacgtgtccttctcgttccgcggcaacgacccggtacgtgaggctatccac
gcggtattcctctactacgccatccgcaacggtatggacatgggcatcgtcaacgccgga
cagctggctatctacgacgacctgcccgccgagctgcgcgatgcggttgaagatgtcatt
cttaaccgtcgcgatgacggcactgagcgtttgctggatttggcggagaaataccgcggc
agcaaaaccgacgaagctgccaacgcccagcaggcggaatggcgtagctgggacgtgaaa
aagcgtctcgaatactcgctggtgaaaggcattaccgaatttatcgaacaggataccgaa
gaagcccgtcagcaggccgcccgcccgattgaggtgattgaagggccgttgatggacggc
atgaacgtggtcggcgacctgttcggcgaagggaaaatgttcctgccgcaggtggtgaaa
tccgctcgcgtgatgaaacaagcggtggcctacctggagccgtttattgaagccagcaaa
gaaaaaggctccagcaacggcaagatggtgatcgccaccgtgaagggcgatgtgcacgat
attggtaaaaatatcgttggcgtggtgctgcaatgtaacaactacgaaatcgtcgatctt
ggcgtgatggtgccagcggagaaaatcctcagaacggcgcgtgaagtgaatgccgatctg
atcggtctttccgggctgattaccccgtcgctggacgaaatggtcaacgtggcgaaagag
atggagcgtcagggctttactatcccgctactgatcggcggcgcaaccacttcgaaagcg
catacggcggtgaaaatcgagcagaactacagcggtccgacggtctacgtgcagaatgct
tcgcgtaccgtgggcgtggtggcggcgctactctccgacacccagcgtgatgactttgtc
gcccgtacccgcaaagagtacgaaaccgtgcgtattcagcacgcccgcaaaaaaccgcgc
acgccgccggtcacgctggaggcggcgcgcgataacgatctggcattcgattgggaacgc
tacaccccgccggtagcccaccgtctgggcgtgcaggaggtggaagccagcatcgaaact
ctgcgcaactatatcgactggacgccgttctttatgacctggtcgctggccggcaaatac
ccgcgcattctggaagatgaggtggtgggcgttgaggcgcagcgtctgtttaaagacgcc
aatgatatgctggataaactgagcgccgagaaactgttgaatccgcgtggcgtggtgggc
ctgttcccggcgaaccgtgtgggtgacgacatcgaaatctatcgcgacgaaacccgtact
catgttctgacggtcagccaccacctgcgccagcagaccgagaaagtcggttttgccaac
tactgtctggcggattttgtcgcgccgaaactgagcggcaaagcggattacatcggtgct
ttcgcggtgaccggcggtctggaggaggatgcgctggcggacgccttcgaagcgcaacac
gacgactataacaagatcatggtgaaagcgattgccgaccgtctggcggaagcgttcgcg
gaatatctgcatgagcgtgtacgtaaggtttactggggatatgcgccgaacgagagcctg
agtaacgacgaattaatccgcgaaaactaccaggggattcgcccggcgccgggttatcct
gcctgcccggaacataccgaaaaaggcactatctggcagctactggatgtcgaaaaacac
accgggatgaagctcaccgaatctttcgccatgtggccaggcgcgtcggtctccggctgg
tacttcagccatcctgagagcaaatacttcgcggtagcgcagatccaacgcgatcaggtg
acagattatgctttccgtaaaggaatgagcgttgaggatgttgagcggtggctcgcgccg
aacctgggttacgatgcggactga
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integrated database retrieval system
