Streptomyces pratensis: Sfla_2013
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Entry
Sfla_2013 CDS
T01647
Name
(GenBank) 2-oxoglutarate dehydrogenase, E1 subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sfa
Streptomyces pratensis
Pathway
sfa00020
Citrate cycle (TCA cycle)
sfa00630
Glyoxylate and dicarboxylate metabolism
sfa00785
Lipoic acid metabolism
sfa01100
Metabolic pathways
sfa01110
Biosynthesis of secondary metabolites
sfa01120
Microbial metabolism in diverse environments
sfa01200
Carbon metabolism
sfa01210
2-Oxocarboxylic acid metabolism
Module
sfa_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sfa_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sfa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Sfla_2013
00630 Glyoxylate and dicarboxylate metabolism
Sfla_2013
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Sfla_2013
Enzymes [BR:
sfa01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
Sfla_2013
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
Sfla_2013
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
Sfla_2013
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
Sfla_2013
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
Transket_pyr
2-oxoacid_dh
OxoGdeHyase_C
2-oxogl_dehyd_N
Trypco1
Motif
Other DBs
NCBI-ProteinID:
ADW03447
UniProt:
A0A8D4BBB8
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All DBs
Position
2447195..2451046
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AA seq
1283 aa
AA seq
DB search
MISAVHHLVKRKRAVAAVSSQSPSNSSISTDQEAGSGSNPAAAFGPNEWLVDEIYQQYLQ
DPNSVDRAWWDFFADYKPGTSGTADKPVPAPTGAVTPAPAATNGATAQAPAAPPAAPAAP
AAAAPAAPAAPAKAAPAAPAKAAPAKAAPAAAKADASTEAPAGPEYVTLRGPSAAVAKNM
NASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMN
YSFAVKDGKPTLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVR
RARVGKLGMDDFSGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDT
LNKLGISKVMTLTSTYDHRVIQGAASGEFLRVLAQLLLGENDFYDEIFKALRIPYEPVRW
LKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDL
ERDFAVGGFAGKTMMKLRDILGVLRESYCRTTGIEFMHIQEPKERKWLQDRVERPRPAPE
REEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVI
GMAHRGRLNVLANIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIK
VSLAANPSHLEAVDPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNM
SQLRGYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRV
ARLAFEYRQTFNKDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIG
RGDITLEEAEQALQDFQGQLEKVFAEVREATSAPSQPHVPDVQAEFPVSVGTAVSSEVVK
LIAESQVNIPDGITVHPRLLPQMQRRAASVDNGTIDWGMGETLAIGSLLMEGTPVRLAGQ
DTRRGTFGQRHAVLVDQKTGEDYTPLLYLSEDQARYNVYDSLLSEYAAMGFEYGYSLARP
ESLVIWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPER
FLQMCAQDNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKVEEFTT
GGFRPVIGDETVGAEAVRKVVFVSGKLYYDLDAEREKRGDTETAIIRLERLYPLPGAEIQ
AEIAKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSS
PAVGSAKRHQAEQTQLVNEVFEA
NT seq
3852 nt
NT seq
+upstream
nt +downstream
nt
ttgatttccgctgtccatcaccttgtgaagcggaagagggcggttgccgccgtgtcgtct
cagtcccccagtaactcgagcatctcgaccgatcaagaagcgggctccgggtccaacccg
gccgccgctttcggccccaatgagtggctcgtcgacgagatctaccagcagtacctccag
gaccccaactcggtcgaccgcgcctggtgggacttcttcgccgactacaagccgggtacg
tccggcacggcggacaagcccgtccccgcacccacgggagcggtgaccccggccccggcc
gcgaccaacggcgccacggcacaggctccggccgcgccgccggcggccccggccgcaccc
gcggccgccgctccggcggctccggccgccccggcgaaggccgctcccgccgctcccgcc
aaggcggcacccgcgaaggcggccccggccgccgcgaaggctgacgcctcgaccgaggcc
ccggccggccccgagtacgtgacgctgcgcggcccgtcggccgccgtcgcgaagaacatg
aacgcctccctggagctgccgacggccacgtcggtccgcgccgtgccggtgaagctgctc
ttcgacaaccgcatcgtcatcaacaaccacctgaagcgggcccgtggcgggaagatctcc
ttcacgcacctcatcgggtacgcgatggtgcaggccctcaaggccatgccgtcgatgaac
tactccttcgcggtgaaggacggcaagccgaccctggtcaagccggagcacgtgaacctc
ggcctcgccatcgacctggtgaagccgaacggcgaccgtcagctcgtcgtcgcggccatc
aagaaggccgagaccctcaacttcttcgagttctggcaggcctacgaggacatcgtccgc
cgtgcccgcgtcggcaagctcggcatggacgacttctccggggtcaccgcctcgctgacg
aaccccggcggcatcggcaccgtgcactcggtgccccgcctgatgcccggacagggcctc
atcatgggtgtcggcgccatggactaccccgcggagttccagggcacctcccaggacacc
ctgaacaagctgggtatctcgaaggtcatgaccctgacctcgacgtacgaccaccgggtc
atccagggtgccgcgtccggcgagttcctccgcgtcctggcccagctgctgctcggcgag
aacgacttctacgacgagatcttcaaggcgctgcgcatcccctacgagccggtccgctgg
ctcaaggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcgcgggtcttcgag
ctgatccactcctaccgggtccgcggtcacgtgatggccgacaccgacccgctggagtac
cgccagcgcaagcaccccgacctggacatcaccgagcacggcctcaccctgtgggacctg
gagcgcgacttcgcggtcggcggtttcgccggcaagacgatgatgaagctgcgcgacatc
ctcggcgtcctgcgtgagtcgtactgccgcaccaccggcatcgagttcatgcacatccag
gagccgaaggagcgcaagtggctccaggaccgggtggagcgtccgcgccccgctccggag
cgcgaggagcagctgcggatcctgcgccgcctcaacgccgccgaggcgttcgagacgttc
ctgcagaccaagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtcatc
ccgctgctcgacgcggtcatcgactccgccgccgaggcccgcctcgacgaggtcgtcatc
ggcatggcccaccgcggccggctgaacgtcctggcgaacatcgtgggcaagtcgtacgca
cagatcttccgggagttcgagggcaacctcgacccgcggtcgatgcacggctccggcgac
gtcaagtaccacctgggcgccgagggcaccttcaccggtctggacggcgagcagatcaag
gtctcgctggccgccaacccctcgcacctggaggccgtcgacccggtcctcgagggcatc
gcgcgcgccaagcaggacatcatcaacaagggcggcacggacttcacggtcctgcccgtc
gcgctccacggcgacgcggccttcgcgggccagggcgtcgtcgccgagacgctcaacatg
tcgcagctgcgcggctaccgcaccggcggcaccgtgcacgtggtgatcaacaaccaggtc
ggcttcaccgccgccccggagtcctcacgctcctcgatgtacgccacggacgtggcgcgc
atgatcgaggcgccgatcatccacgtcaacggcgacgacccggaggccgtggtgcgcgtc
gcgcggctcgccttcgagtaccggcagacgttcaacaaggacgtcgtgatcgacctcatc
tgctaccgccgccgcggtcacaacgagggcgacaacccggagttcaccaacccgcagatg
tacaccctgatcgacaagaagcgctcggtgcgcaagctctacaccgagtccctcatcggt
cgtggcgacatcacgctggaagaggccgagcaggcgctccaggacttccaggggcagctg
gagaaggtcttcgccgaggtccgcgaggccacctccgcgccgtcccagccgcacgtcccg
gacgtccaggcggagttcccggtctcggtcggcaccgcggtgtcctccgaggtcgtgaag
ctgatcgccgagtcgcaggtcaacatccccgacggcatcacggtgcacccgcgtctgctg
ccgcagatgcagcgccgcgcggcctcggtggacaacggcacgatcgactggggcatgggc
gagaccctggccatcggttcgctgctgatggagggcaccccggtccggctcgccggccag
gacacccgccgcggcacgttcggtcagcgtcacgccgtcctcgtcgaccagaagaccggc
gaggactacaccccgctgctctacctctccgaggaccaggcccgttacaacgtctacgac
tcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgctggcccgcccg
gagtccctggtgatctgggaggcccagttcggtgacttcgtcaacggcgcccagaccgtc
gtggacgagttcatctcctccgccgagcagaagtggggccagacgtccggcgtcaccctg
ctgctcccgcacggctacgagggccagggcccggaccactcgtccgcgcgcccggagcgc
ttcctgcagatgtgcgcgcaggacaacatgacggtcgcgatgcctaccctcccgtcgaac
tacttccaccttctgcgctggcaggtgcacaacccgcaccacaagccgctgatcgtcttc
accccgaagtcgatgctgcgtctcaaggccgccgcctcgaaggtcgaggagttcaccacc
ggcggcttccgcccggtgatcggcgacgagacggtcggcgccgaggcggtccgcaaggtc
gtgttcgtgtccgggaagctctactacgacctggacgccgagcgcgagaagcgcggcgac
acggagacggcgatcatccggctggagcgtctgtacccgctgccgggtgcggagatccag
gccgagatcgccaagtacccgaacgccgagaagtacctctgggcccaggaggagccggcg
aaccagggtgcgtggccgttcatcgcgctcaacctgatcgaccacctggacctggccgtc
ggcgccgacgtgccgcacggtgagcgcctgcgccgcatctcgcgtccgcacggctcgtcc
ccggcggtcggctcggccaagcgtcaccaggccgagcagacccagctggtcaacgaggtc
ttcgaggcctga
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