Streptomyces fradiae: CP974_07480
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Entry
CP974_07480 CDS
T07648
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sfb
Streptomyces fradiae
Pathway
sfb00010
Glycolysis / Gluconeogenesis
sfb00020
Citrate cycle (TCA cycle)
sfb00620
Pyruvate metabolism
sfb00785
Lipoic acid metabolism
sfb01100
Metabolic pathways
sfb01110
Biosynthesis of secondary metabolites
sfb01120
Microbial metabolism in diverse environments
sfb01200
Carbon metabolism
sfb01210
2-Oxocarboxylic acid metabolism
Module
sfb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CP974_07480 (aceE)
00020 Citrate cycle (TCA cycle)
CP974_07480 (aceE)
00620 Pyruvate metabolism
CP974_07480 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP974_07480 (aceE)
Enzymes [BR:
sfb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CP974_07480 (aceE)
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
QEV11891
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Position
1688374..1691067
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AA seq
897 aa
AA seq
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MTDPTRIQPSELDQLPDRDPEETAEWRASLDAVAAAAGPHRAAYLMRRTLERAQDAGLAL
PKLLETDYVNTIPTAAEAGYGFDGDDELEARITAWNRWNAAAMVTRGSKYGVGGHIATFA
SAAWLYETGFNHFFQGKERDGSGDQLFIQGHASPGIYARAFLDGRLTEAHLDNFRQEAAG
NGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTHRGIKDVSASHVWAFLGDG
EMDEPESTAALALAAREGLDNLTFVVNCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVK
TLWGTAWDELFRLDTTGALVRRLREVPDAQVQTYQTRDAAYIREDFFGKDPALAEMAKLL
SDDKIIECFHSSRGGHESRKVFAAYKAALSHKGAPTVILAQTVKGHTLGKGFASKNANHQ
MKKLTVDEFKEMRDRLGLPIPDSAFADGRVPYGHPGADAPEVRYLHERRAALGGPAPARR
VHPAAALPAPAEKAFTAFDKGSGSQSVATTMAFVRLVKDLVRDKETGRRWVPIVPDEART
FGMESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAVNGQILNEGITEAGSMADFIAASTAY
STHGEPMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHS
PVIAATNPAALTYDPAFAYEVAVIVKEGLRRMYGEGAPGEDPNVFYYLTVYNEPMPQPAK
PAVPGIDEGIVKGLYRFKEGSGAEGAPRTQLLASGTAIHWALDAQRMLAEEWGVTADVWS
ATSWTELRRDALEADAALLRGEERVPYVRQALADAPGPVLAVSDYMRQVPDQIAQWVEQD
YSSLGADGFGLSDTREAARRHFGVDAPSIVVAALAQLARRGEVPASAVKDARERYGL
NT seq
2694 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccacccgcatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgagtggcgggcctcgctcgacgccgtggccgccgcggccgggccgcac
cgtgccgcgtacctgatgcgccgcaccctggagcgggcccaggacgccggtctggcgctg
ccgaagctgctcgagacggactacgtcaacaccatcccgaccgccgccgaggccggttac
ggcttcgacggcgacgacgagctggaagcccggatcaccgcgtggaaccggtggaacgcc
gccgccatggtgacccgcggctccaagtacggcgtcggcggccacatcgccaccttcgcc
tccgccgcctggctctacgagacgggcttcaaccacttcttccagggcaaggagcgggac
ggctcgggcgaccagctgttcatccagggccacgcctcccccggcatctacgcccgcgcc
ttcctcgacggccgcctcaccgaggcgcacctcgacaacttccgccaggaggccgccggc
aacggcctgccctcctacccgcacccgcggcgcctgccgtggctgtgggagttcccgacc
gtctccatgggcctcggcccgctctccgcgatctaccaggcgcgcttcaaccggtacctg
acccaccgcggcatcaaggacgtctccgcctcgcacgtgtgggcgttcctcggcgacggc
gagatggacgagcccgagtcgaccgcggccctcgccctggccgcccgcgagggcctggac
aacctgaccttcgtcgtcaactgcaacctgcagcgcctcgacggcccggtccgcgccaac
ttcaagatcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtcaag
accctgtggggcaccgcctgggacgagctgttccggctcgacacgaccggcgccctcgtc
cgccgcctccgcgaggtcccggacgcgcaggtccagacgtaccagacgcgtgacgcggcc
tacatccgcgaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctg
tccgacgacaagatcatcgagtgcttccactcctcgcgcggcggccacgagtcccgcaag
gtcttcgccgcgtacaaggccgcgctgagccacaagggcgcgccgaccgtgatcctcgcc
cagaccgtcaagggccacaccctcggcaagggcttcgcgtccaagaacgccaaccaccag
atgaagaagctgacggtggacgagttcaaggagatgcgcgaccgcctcggcctgcccatc
cccgacagcgccttcgccgacggccgggtgccgtacggccaccccggcgccgacgccccc
gaggtgcgctacctgcacgagcgccgcgccgcgctcggcggccccgccccggcccgccgc
gtccacccggcggcggcgctgccggccccggcggagaaggcgttcaccgcgttcgacaag
ggctccggctcgcagtccgtcgccaccaccatggcgttcgtgcgcctggtgaaggacctg
gtccgcgacaaggagaccggcaggcgctgggtgccgatcgtccccgacgaggcccgcacc
ttcggcatggagtcgctcttcccgtcgctcggcatctactcgccgaaggggcagacgtac
gagccggtcgaccgcgaccagctgatgtactacaaggaggccgtcaacggccagatcctg
aacgagggcatcaccgaggccggctccatggccgacttcatcgccgcgtccaccgcgtac
tccacgcacggcgagccgatgatcccgttctacatcttctactcgatgttcggctggcag
cggaccgccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggc
gccaccgccggccgcaccaccctgaccggtgaggggctccagcacgcggacggccactcc
cccgtcatcgcggcgaccaacccggcggcgctgacgtacgacccggccttcgcctacgag
gtcgcggtgatcgtcaaggagggtctgcgccggatgtacggcgagggcgccccgggcgag
gacccgaacgtcttctactacctgaccgtctacaacgagcccatgccgcagccggccaag
ccggccgtccccggcatcgacgagggcatcgtcaagggcctgtaccggttcaaggagggc
tcgggcgccgagggcgcgccgcgcacccagctcctcgcctccggcacggcgatccactgg
gcgctggacgcgcagcggatgctggccgaggagtggggcgtcaccgccgacgtgtggtcc
gcgacctcctggacggagctgcggcgcgacgcgctggaggccgacgcggcgctgctgcgc
ggcgaggagcgcgtgccgtacgtacgccaggcgctggccgacgcgccgggtccggtactg
gcggtcagcgactacatgcggcaggtcccggaccagatcgcgcagtgggtcgagcaggac
tactcgtcgctgggtgccgacggcttcggcctgtcggacacccgcgaggcggcccgccgc
cacttcggggtggacgccccgtcgatcgtggtggccgcgctggcccagctcgcccgccgc
ggcgaggtcccggcctccgcggtgaaggacgcccgcgagcggtacggcctgtag
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