Streptomyces fradiae: CP974_21070
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Entry
CP974_21070 CDS
T07648
Name
(GenBank) multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sfb
Streptomyces fradiae
Pathway
sfb00020
Citrate cycle (TCA cycle)
sfb00630
Glyoxylate and dicarboxylate metabolism
sfb00785
Lipoic acid metabolism
sfb01100
Metabolic pathways
sfb01110
Biosynthesis of secondary metabolites
sfb01120
Microbial metabolism in diverse environments
sfb01200
Carbon metabolism
sfb01210
2-Oxocarboxylic acid metabolism
Module
sfb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sfb_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sfb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
CP974_21070
00630 Glyoxylate and dicarboxylate metabolism
CP974_21070
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CP974_21070
Enzymes [BR:
sfb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
CP974_21070
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
CP974_21070
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
CP974_21070
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
CP974_21070
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
QEV14068
LinkDB
All DBs
Position
complement(4667686..4671579)
Genome browser
AA seq
1297 aa
AA seq
DB search
MSSQSPSNSSISTDQDGRGQSPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GASGSADKPAGEAAGAAGSVTRPAQPAEAPTAQAPAAQAAQAQPAQPAAPAGQVPAPAAP
QPAAPAQAQAPAPAQAAPAAPAEPAERPAPAKAAPAKPAAAKPAAKAAPAAEGAAGPAFV
TLRGPAGAVAKNMDASLDMPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHIIGY
AMVQAIKAMPSMNWSYQVKDGKPTLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLG
FFEFWQAYEDIVRRARANKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSM
DYPAEFQGTSQDTLNKLGVSKVMTLTSTYDHRVIQGAASGEFLRIVANLLLGEDGFYDDV
FKSLRIPYEPVRWLRDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPD
LDITEHGLTLWDLEREFAVGGFGGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKW
IQDRVERPHSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVI
DSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGA
EGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVVRAKQDIIGKAGTDFTVLPVALHGDAA
FAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIF
HVNGDDPEACVRVARLAFEFRQTFNKDVVIDLICYRRRGHNEGDNPQFTNPQMYTLIDQK
RSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFTEVREATAQPSPAAGVDPQAGFP
ADGVSTAVSQEVVKRVAESQVNIPDHITVHPRLLPQLQRRAQSIYDGTIDWGMGETLAIG
SLLMEGVPVRLAGQDSRRGTFGQRHAVLVDQVTGEDYTPMLYLAEDQARYNVYDSLLSEY
AAMGFEYGYSLARPDALVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGY
EGQGPDHSSARPERFLQMCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSML
RLKAAASKLDEFTTGSFRPVIGDEKADPAAVRKVVFCSGKVYYDLEAERQKRGVTDTAII
RLERLYPLPGAELQAEIAKYAGAEKYIWAQEEPANQGAWPFIALNLIDHLDLAVGADIPQ
GERLRRISRPHSSSPAVGSAKRHQAEQMQLVNEVFDA
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctcgaccgaccaagacggccggggccag
agccctgcggccgccttcggtgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggacccgaattcggtcgaccgcgcctggtgggacttcttcgccgactacaagccg
ggcgcgtccggctcggcggacaagcccgcaggcgaggccgccggggccgcgggctccgtg
acgcggccggcccagccggcggaggcgcccaccgcacaggcccccgccgcgcaggccgcc
caggcccagcccgcccagccggcggcacccgccggccaggtccccgccccggccgcgccg
cagccggccgcacccgcgcaggcccaggcccccgccccggcgcaggccgcccccgcggcg
cccgccgagccggcggagcggcccgcgcccgccaaggccgcgcccgccaagcccgccgcc
gccaagcccgccgccaaggcggcccccgcggccgagggcgccgcgggcccggcgttcgtg
acgctgcgcggcccggccggcgccgtcgcgaagaacatggacgcctcgctggacatgccg
acggccacctcggtccgcgccgtcccggtgaagctgctgttcgacaaccgcatcgtcatc
aacaaccacctgaagcgggcccgcggcgggaagatctccttcacgcacatcatcggctac
gcgatggtgcaggcgatcaaggcgatgccctccatgaactggtcgtaccaggtcaaggac
ggcaagccgaccctggtcaagccggagcacgtcaacctcggcctcgccatcgacctggtg
aagccgaacggcgaccgccagctcgtcgtcgcggccatcaagaaggccgagacgctgggc
ttcttcgagttctggcaggcgtacgaggacatcgtccgccgcgcccgcgcgaacaagctc
accatggacgacttcaccggcgtgacggtctccctgaccaaccccggcggcctcggcacg
gtccactccgtgccgcgcctgatgcccggccagtcggtgatcatgggcgtcggctcgatg
gactacccggccgagttccagggcacgtcccaggacaccctgaacaagctgggcgtctcc
aaggtgatgaccctcacctcgacgtacgaccaccgggtcatccagggcgccgcgtccggc
gagttcctgcggatcgtcgccaacctcctcctcggcgaggacggcttctacgacgacgtc
ttcaagtcgctgcgcatcccctacgagccggtccgctggctgcgggacatcgacgcgtcg
cacgacgacgacgtcaccaaggccgcgcgcgtcttcgagctgatccactcctaccgggtc
cgcggccacgtcatggccgacaccgacccgctggagtaccgccagcgcaagcaccccgac
ctggacatcaccgagcacggcctcaccctgtgggacctggagcgggagttcgcggtcggc
ggcttcggcggcaagtcgatgatgaagctgcgcgacatcctcggcgtcctgcgcgactcg
tactgccgcaccaccggcatcgagttcatgcacatccaggacccgaagcagcgcaagtgg
atccaggaccgcgtcgagcgcccgcactccaagccggagcgcgaggagcagctgcgcatc
ctgcgccggctgaacgcggcggaggcgttcgagaccttcctccagaccaagtacgtcggg
cagaagcggttcagcctggagggcggcgagtccgtcatcccgctgctggacgccgtgatc
gactcggcggccgagtcgcgcctcgacgaggtcgtcatcggcatggcccaccgcggccgg
ctgaacgtcctcgcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgag
ggcaatctcgacccgaagtcgatgcacggctccggcgacgtcaagtaccacctgggcgcc
gaggggaccttcaccggcctcgacggcgagcagatcaaggtcagcctggtcgccaacccg
tcccacctggaggccgtcgacccggtcctggagggcgtcgtccgcgccaagcaggacatc
atcggcaaggccggcacggacttcaccgtcctgcccgtcgccctccacggcgacgcggcc
ttcgccggccagggcgtcgtcgccgagacgctgaacatgtcgcagctgcgcggctaccgc
accggcggcacggtccacatcgtcatcaacaaccaggtcggcttcaccgccgccccggag
tcctcgcgctcctcgatgtacgccaccgacgtggcccgcatgatcgaggcgccgatcttc
cacgtgaacggcgacgacccggaggcgtgcgtccgcgtggcgcggctcgccttcgagttc
cgccagacgttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcgggcac
aacgagggcgacaacccgcagttcacgaacccgcagatgtacacgctgatcgaccagaag
cgctcggtgcgcaagctctacaccgagtcgctgatcggccgcggcgacatcaccctggag
gaggcggagcaggcgctccaggacttccagggccagctggagaaggtcttcaccgaggtc
cgcgaggccacggcgcagcccagcccggcggccggggtcgacccgcaggccggcttcccg
gcggacggcgtgagcacggccgtgtcgcaggaggtcgtcaagcgggtcgcggagtcgcag
gtcaacatccccgaccacatcacggtccacccgcggctgctgccgcagctccagcgccgc
gcgcagtcgatctacgacggcacgatcgactggggcatgggcgagaccctcgccatcggc
tcgctgctgatggagggcgtcccggtccgcctggccggccaggactcccgccgcggcacc
ttcggccagcgccacgcggtcctggtggaccaggtgaccggcgaggactacacgccgatg
ctgtacctcgccgaggaccaggcccggtacaacgtctacgactcgctgctcagcgagtac
gcggcgatgggcttcgagtacggctactcgctggcccgcccggacgcgctggtcatgtgg
gaggcgcagttcggcgacttcgtcaacggcgcgcagaccgtcgtggacgagttcatctcc
tccgccgagcagaagtggggccagacctccggcgtcacgctgctgctgccgcacggctac
gagggccagggcccggaccactcgtccgcccgcccggagcgcttcctccagatgtgcgcg
cagaacaacatgacggtcgccatgccgacgctgccgtcgaactacttccacctcctgcgg
tggcaggtgcacaacccgcaccacaagccgctggtcgtcttcacgccgaagtcgatgctg
cgcctgaaggccgccgcgtcgaagctggacgagttcaccaccggctcgttccgcccggtg
atcggcgacgagaaggccgatccggccgccgtccggaaggtcgtcttctgctccggcaag
gtctactacgacctggaggccgagcggcagaagcgcggtgtcacggacacggcgatcatc
cggctggagcggctgtacccgctgccgggcgccgagctccaggccgagatcgccaagtac
gcgggcgccgagaagtacatctgggcgcaggaggagccggcgaaccagggtgcgtggccg
ttcatcgcgctcaacctgatcgaccacctggacctggcggtcggcgccgacatcccgcag
ggcgagcgcctgcgccgcatctcgcggccgcacagctcgtcgccggcggtcggctcggcc
aagcggcaccaggcggagcagatgcagctcgtgaacgaggtcttcgacgcctga
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