Spirochaeta africana: Spiaf_0377
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Entry
Spiaf_0377 CDS
T01811
Name
(GenBank) 3-hydroxy-3-methylglutaryl CoA synthase
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
sfc
Spirochaeta africana
Pathway
sfc00280
Valine, leucine and isoleucine degradation
sfc00650
Butanoate metabolism
sfc00900
Terpenoid backbone biosynthesis
sfc01100
Metabolic pathways
sfc01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
sfc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
Spiaf_0377
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
Spiaf_0377
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
Spiaf_0377
Enzymes [BR:
sfc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
Spiaf_0377
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Motif
Pfam:
HMG_CoA_synt_N
HMG_CoA_synt_C
Trp_repressor
ACP_syn_III
Motif
Other DBs
NCBI-ProteinID:
AFG36482
UniProt:
H9UG39
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All DBs
Position
complement(459658..460938)
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AA seq
426 aa
AA seq
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MSTASVGISDIQLYIPPGKISLDRLMEFRVQHDEFPERKLQRAIEVTGQQAIRFPLPFQD
NSTLAAAAARDLYVRRGDKNPDKLRYIAVGTETAVDHSKPIAAYLQGMLQRSGVAVGNTL
SSFQVQHACAGGTVSLLGIGALLQAGGRDGDAGLVVCSDIARYDAPSTAEITQGAGAVAM
HMERNPELLEFDLASTGYCSNDVDDFFRPLGSTTAKVKGSYSVQCYHEAFDGALADHAER
LGITPAQALRETEIFVLHVPFKNMALTALTKAVEKHLDMDEEQAAGFLRERGFQQSLEAS
TRVGNIYSGSAYLAMTFALQERYQTLGTELVGKNVMIASYGSGNTMLVFRATVAAGAPAV
ISGWNLDAIWDHEQPENLDAYLAWLATPTEREALNQRLEAADIPAGMFALDSVREDGYRE
YSFHGG
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atgagtacagccagcgtaggaatcagtgatatccagctgtatattcctcccggcaagata
tcccttgatcgtttgatggagtttcgcgttcagcacgacgagtttccggaacgcaagctg
caacgagcgatcgaggtaaccgggcagcaggccatccggttcccgctgccgtttcaggac
aattctaccctcgcggcagctgctgcccgtgacctgtatgtccgtcgcggcgacaagaat
ccggataaactgcgctatattgcagtaggcaccgaaaccgccgttgaccattccaaaccg
atagcggcctacctgcaggggatgctgcagcgcagcggcgttgccgtaggcaataccctc
agcagctttcaggtgcagcacgcctgtgccggcggcacggtttcgctgcttgggatcggg
gcgctgctgcaggcgggcggacgcgatggcgatgccggcctggtagtctgctccgatatc
gcccgctacgacgcaccctccacggcagagatcacccagggagccggggcagtggccatg
catatggagcgcaaccccgagctgctggagtttgatctggcctctaccgggtattgttcc
aatgatgtcgacgattttttccgcccgctgggcagcaccactgccaaggtcaaaggcagc
tactcggtgcagtgctaccacgaggcattcgatggcgccctggcagaccatgccgagcgt
ctgggtatcaccccggcacaggccctgcgggagaccgagatcttcgtactgcatgtaccg
ttcaagaacatggccctgaccgcccttaccaaagcagtagagaaacatctcgacatggac
gaggaacaggcagccggattcctgcgcgaacgcggcttccagcagtccctcgaggcctcg
acccgggtcgggaacatctactccggctctgcgtatctggccatgacattcgctctgcag
gagcgctaccagacacttggcacggagcttgtcggcaagaatgtaatgattgccagctat
ggctcgggcaataccatgctggtcttccgcgcaacggtagccgccggggcacccgcggtg
atatcgggctggaacctggatgctatctgggatcacgaacaaccggagaatctggatgcc
tatctggcctggctggcgacgccaaccgagcgcgaagcgctgaaccagcgtctggaggca
gcagatattccggcaggaatgtttgcactggactcggtacgcgaggatggctacagagag
tacagcttccatggcggataa
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