KEGG   Streptococcus ferus: NCTC12278_01082
Entry
NCTC12278_01082   CDS       T07132                                 
Symbol
yitJ
Name
(GenBank) bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
sfer  Streptococcus ferus
Pathway
sfer00270  Cysteine and methionine metabolism
sfer00450  Selenocompound metabolism
sfer00670  One carbon pool by folate
sfer01100  Metabolic pathways
sfer01110  Biosynthesis of secondary metabolites
sfer01120  Microbial metabolism in diverse environments
sfer01230  Biosynthesis of amino acids
Module
sfer_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:sfer00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    NCTC12278_01082 (yitJ)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    NCTC12278_01082 (yitJ)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    NCTC12278_01082 (yitJ)
Enzymes [BR:sfer01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     NCTC12278_01082 (yitJ)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     NCTC12278_01082 (yitJ)
SSDB
Motif
Pfam: S-methyl_trans MTHFR
Other DBs
NCBI-ProteinID: SQF40512
UniProt: A0A2X3Y149
LinkDB
Position
1:complement(1051755..1053587)
AA seq 610 aa
MSKLLDKLKTDILVADGAMGTLLYANGLESCHEYYNLSQPQQILAIHKAYIEAGADIIQT
NTYAAKRHQLKGFGYDGQIKAINQEAVALARQAAGKDVFVLGTIGASRGLRQCDLSLEEI
VSETVEQVNYLLETARIDGLLFETYYDIEELSAVLKAIRPITDLPIIANISLYEAGITEN
GRPLVEAFSQLVMLGADVVGLNCHLGPYHMIQSLKQVPLFAQSYLSVYPNASLLSFSDNG
ETNQFAFSQNADYFEHCAKLFVEEGVRLIGGCCGTTPDHIKAIKRGIKGLKPIDRKIITP
LMTEEELIKQVQKSETLVDKVKKEVTIIAEIDPPKTLDIDRFVAGVKALDKKGIAAITLA
DNSLARTRICNVSIASLLKEEIDTPFLLHLACRDHNMIGLQSRLLGMHIHGFDHLLAITG
DPSKIGDFPGATSVYDATSFKLLSMIKQLNQGKGYSGASIKQATNFTVAAAFNPNVKNLS
RTGRLIEKKIAAGADYFITQPIFNQNQIDELSQLTKPYEEPFFIGIMPITSYNNAVFLHN
EVPGIDLSEEFLARLEAVKEDKEACQKLALEESKALIDKALEHFNGIYLITPFLRYDLTS
SLIDYIQKRA
NT seq 1833 nt   +upstreamnt  +downstreamnt
atgtccaaattgctagataaactgaaaacagacattctagtggcggacggtgccatgggc
actctcctgtatgccaatggactggaatcttgccatgaatactacaacctgagtcagcct
cagcagatcttagccattcacaaagcctatattgaggccggagctgacattattcagacc
aatacgtatgccgctaagcggcaccagttgaaagggtttggctatgatgggcaaatcaaa
gccatcaaccaggaagcggtagccttggcacgtcaagcagcaggcaaagatgtttttgtc
ctgggaactattggtgcttctcgaggccttaggcaatgtgatttgtccttagaagagatt
gtttctgaaacggtcgaacaggtaaactatctccttgagacggcaaggattgatggttta
ctgtttgagacctactacgatattgaagagctgtcagctgttctcaaggctattcgtcca
atcactgatctgccaattatcgccaatatttctctttatgaggcaggtattacagaaaat
ggacgtcctctcgtcgaggcctttagtcagctggtcatgctgggggctgatgtggttggt
ctcaactgccatctggggccttaccacatgattcagtctttgaagcaggtgccgttgttt
gcccagtcctatttgtctgtctatccgaatgccagtctgctgtcgttttcggataatggt
gagacgaatcaatttgcttttagccaaaatgctgactattttgagcactgcgctaaactt
tttgtcgaagaaggtgtgcgtctaattggtggctgttgcggaaccacaccagaccacatt
aaagctattaaacgcgggattaaaggattaaaaccgattgaccgcaaaatcatcacccct
ctaatgacggaggaagaactgattaagcaggttcaaaaaagtgaaaccttggtggataag
gtcaaaaaagaggtcactattatcgctgaaattgatccacctaagactttagatatcgac
cgatttgtggcaggggtcaaggcactggataagaaaggcattgcagccatcacgctggcc
gataattcgctggccaggacccgtatctgtaatgtcagcattgctagtcttctcaaggag
gagattgacacaccctttctgctccatctggcctgccgcgatcacaatatgattggtctt
caatcgcgacttttagggatgcacattcatggctttgaccacttgctggcgattacagga
gacccgtctaaaatcggggacttcccaggtgcgaccagtgtctatgatgcgaccagcttt
aaacttctgtctatgattaaacagctaaatcaggggaaggggtacagtggtgccagtatc
aagcaggcgacgaatttcacggttgcagcagcctttaatcctaatgtgaaaaatctcagc
cgaaccggtcgcctcatcgaaaagaagatagctgcgggagcggattatttcatcacccag
cctattttcaatcaaaatcaaattgacgaactcagtcagctgaccaagccttatgaagaa
cctttcttcattggaattatgccaatcacctcttacaacaatgctgtctttctgcacaat
gaggttccgggaattgatttgtcagaagaattcctagccagattggaagccgtcaaagag
gacaaggaagcttgtcagaagctggctctggaagagagtaaggcattgattgataaggcc
ttagagcattttaatgggatttaccttattacgcctttcctgaggtatgatttgacgagt
agtttaattgattacatacaaaaaagagcctga

DBGET integrated database retrieval system