Streptomyces ferrugineus: IM697_09695
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Entry
IM697_09695 CDS
T07428
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sfeu
Streptomyces ferrugineus
Pathway
sfeu00010
Glycolysis / Gluconeogenesis
sfeu00020
Citrate cycle (TCA cycle)
sfeu00620
Pyruvate metabolism
sfeu00785
Lipoic acid metabolism
sfeu01100
Metabolic pathways
sfeu01110
Biosynthesis of secondary metabolites
sfeu01120
Microbial metabolism in diverse environments
sfeu01200
Carbon metabolism
sfeu01210
2-Oxocarboxylic acid metabolism
Module
sfeu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfeu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
IM697_09695 (aceE)
00020 Citrate cycle (TCA cycle)
IM697_09695 (aceE)
00620 Pyruvate metabolism
IM697_09695 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IM697_09695 (aceE)
Enzymes [BR:
sfeu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
IM697_09695 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
QOV38619
UniProt:
A0A7M2SRK8
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Position
complement(2133429..2136176)
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AA seq
915 aa
AA seq
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MASGSDRNPIIIGGLPSQVPDFDPEETQEWLDSLDAAVDERGRERARYLMLRLIERAREK
RVAVPEMRSTDYVNTIATKDEPFFPGNEEIERKILNATRWNAAVMVSRAQRPGIGVGGHI
ATFASSASLYDVGFNHFFRGKDEGDGGDQVFFQGHASPGIYARAFLLDRLSEHNLDGFRQ
EKSKAPYGLSSYPHPRLMPDFWEFPTVSMGLGPIGAIYQARMNRYMEARGIADTSKSHVW
AFLGDGEMDEPESLGQLSIAAREGLDNLTFVVNCNLQRLDGPVRGNGKVIQELESIFRGA
GWNVIKLIWDRSWDPLLAQDRDGILVNRMNTTPDGQYQTYATETGGYIRDHFFGDDQRLR
AMVEGMTDDQILHLGRGGHDHRKIFAAFSAAKAHKGQPTVILAKTIKGWTLGPNFEGRNA
THQMKKLTVDDLKRFRDRLHLPIADKDLESGLPPYYHPGRDSEEIQYMHDRRKGLGGYVP
TRIVRSKPLALPDDKTYATVKKGSGQQSIATTMAFVRLLKDLMRDKELGKRFVLIAPDEY
RTFGMDSFFPSAKIYNPLGQQYESVDRDLLLAYKESPQGQMLHDGISEAGCTASLIAAGS
AYATHGEPLIPVYVFYSMFGFQRTGDQFWQMSDQLARGFVLGATAGRTTLTGEGLQHADG
HSQLLASTNPGCVAYDPAYSYEIAHIVQDGLRRMYGGDAEHPHGEDVFYYLTVYNEPIQH
PAEPENVDVEGILKGVYRLSEGSSGSIPAQIMASGVAVPWAVEAQKILAEDWNVKADVWS
ATSWNELRREAVECEEHNLLHPEEEQRVPYVTQKLNGAEGPFVAVSDWMRSVPDQIARWV
PGTYQSLGADGFGFADTRGAARRFFHIDAQSIVVAVLTELAKEGKVDRSALKQAIDRYQL
LDVSAADPGAAGGDA
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
gtggcttccggatccgatcgcaacccgatcatcattggcggccttccgagtcaggttcct
gacttcgatcccgaggaaacccaggagtggctcgactccctcgacgccgccgtcgacgag
cgtggccgggagcgggcccgctatctgatgctgcggctgatcgagcgggcccgcgagaag
cgcgtggccgtgcccgagatgcgcagcacggactacgtcaacacgatcgccaccaaggac
gagccgttcttcccgggcaacgaggagatcgagcgcaagatcctgaacgcgacccggtgg
aacgccgcggtcatggtgtcccgggcccagcgccccggcatcggcgtcggcgggcacatc
gccacgttcgcctcctccgcctcgctctacgacgtgggcttcaaccacttcttccggggc
aaggacgagggcgacggcggcgaccaggtcttcttccagggccacgcctccccgggcatc
tacgcccgcgcgttcctcctcgaccgcctcagcgagcacaacctggacgggttccgccag
gagaagtcgaaggcgccgtacggcctgtcgtcctacccgcacccgcggctgatgccggac
ttctgggagttcccgaccgtgtcgatgggcctcggcccgatcggcgcgatctaccaggcg
cggatgaaccgctacatggaggcgcgcggcatcgcggacacctccaagtcgcatgtgtgg
gcgttcctcggcgacggcgagatggacgagccggagtcgctcggccagctgtccatcgcc
gcgcgcgagggcctggacaacctcaccttcgtggtcaactgcaacctgcagcgcctggac
ggcccggtgcggggcaacggcaaggtcatccaggagctggagtcgatcttccgcggcgcc
ggctggaacgtcatcaagctgatctgggaccgcagctgggacccgctgctcgcgcaggac
cgcgacggcatcctggtcaaccggatgaacaccacgccggacggccagtaccagacgtac
gccaccgagaccggcggctacatccgcgaccacttcttcggcgacgaccagcggctgcgc
gcgatggtcgagggcatgaccgacgaccagatcctgcacctgggccgcggcggtcacgac
caccggaagatcttcgcggcgttctccgcggccaaggcgcacaagggccagccgacggtg
atcctcgccaagacgatcaagggctggacgctcggccccaacttcgagggccgcaacgcc
acgcaccagatgaagaagctgacggtcgacgacctcaagcgcttccgcgaccggctgcac
ctgccgatcgccgacaaggacctggagagcgggctcccgccgtactaccacccggggcgg
gactccgaggagatccagtacatgcacgaccgccgcaaggggctcggcggttacgtcccg
acgcgcatcgtgcgctccaagccgctggcactgccggacgacaagacgtacgcgaccgtg
aagaagggctcgggccagcagtccatcgcgacgaccatggccttcgtccggctcctcaag
gacctcatgcgggacaaggagctcggcaagcggttcgtgctgatcgcgccggacgagtac
cgcacgttcggcatggactccttcttcccgagcgcgaagatctacaacccgctgggccag
cagtacgagtcggtcgaccgcgatctgctgctcgcctacaaggagtccccgcaggggcag
atgctgcacgacggcatctcggaggccggctgcacggcttccctcatcgcggcgggctcg
gcgtacgccacccatggcgagccgctgatcccggtgtacgtcttctactcgatgttcggt
ttccagcgcaccggcgaccagttctggcagatgtccgatcagctcgcgcgcggtttcgta
ctgggcgcgaccgccggacgtacgacgctgaccggtgagggtctgcagcacgcggacggc
cactcgcagctgctcgcctcgaccaacccgggctgtgtcgcctacgacccggcgtactcg
tacgagatcgcgcacatcgtgcaggacggtctgcgccggatgtacggcggcgacgcggag
cacccgcacggcgaggacgtcttctactacctcaccgtctacaacgagccgatccagcac
ccggccgagccggagaacgtcgacgtcgagggcatcctcaagggcgtctaccggctcagc
gagggctcctcgggttcgatcccggcgcagatcatggcgtccggtgtggccgtcccctgg
gcggtcgaggcgcagaagatcctcgccgaggactggaacgtcaaggcggacgtctggtcg
gcgacctcgtggaacgagctgcggcgcgaggccgtggagtgcgaggagcacaatctgctg
cacccggaggaggagcagcgggtgccgtatgtcacacagaagctcaacggcgccgagggg
ccgttcgtggccgtctccgactggatgcgatcggttccggaccagatcgcgcgctgggtg
ccgggcacgtaccagtcgctgggtgcggacggcttcggcttcgcggacacccgtggcgcg
gcccggcgcttcttccacatcgacgcgcagtcgatcgtggtggcggtgctgaccgagctg
gccaaggagggcaaggtggaccggtcggcgctgaagcaggcgatcgaccgttaccagctg
ctcgatgtgtcggcggcggatccgggggcggccgggggcgacgcgtag
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