Streptomyces ferrugineus: IM697_10940
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Entry
IM697_10940 CDS
T07428
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sfeu
Streptomyces ferrugineus
Pathway
sfeu00010
Glycolysis / Gluconeogenesis
sfeu00020
Citrate cycle (TCA cycle)
sfeu00620
Pyruvate metabolism
sfeu00785
Lipoic acid metabolism
sfeu01100
Metabolic pathways
sfeu01110
Biosynthesis of secondary metabolites
sfeu01120
Microbial metabolism in diverse environments
sfeu01200
Carbon metabolism
sfeu01210
2-Oxocarboxylic acid metabolism
Module
sfeu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfeu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
IM697_10940 (aceE)
00020 Citrate cycle (TCA cycle)
IM697_10940 (aceE)
00620 Pyruvate metabolism
IM697_10940 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
IM697_10940 (aceE)
Enzymes [BR:
sfeu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
IM697_10940 (aceE)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Transket_pyr
PepSY_TM_like_2
Motif
Other DBs
NCBI-ProteinID:
QOV38840
UniProt:
A0A7M2SR43
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All DBs
Position
complement(2399942..2402647)
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AA seq
901 aa
AA seq
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MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVAKAAGPHRAAFLMRRTLERAEGTGVAL
PKLLETDYVNTIPTAAEPSVPGDEAMESRITAWNRWNAAAMVTRGSKHGVGGHIATFASA
AWLYETGFNHFFRGKEADGSGDQLYIQGHASPGIYARAFLDGRLTEQHLDNFRQEAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTARGIKDVSNSHVWAFLGDGEM
DEPESTAALALASREGLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVKTL
WGTAWDELFQLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGADPALVEMARLLSD
DKILECFHLSRGGHEARKVYAAYKAALDHKGAPTVILAQTVKGFTLGEGFASKNANHQMK
KLTVDEFKKMRDLLELPIADSAFVDGVVPYGHPGADSAEVRYLQERRAALGGPAPARRTH
ALAPLPAPAEKAFASFDKGSGSQNVATTMAFVRLIKDLVRDKETGRRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKNGQILNEGITEAGSMADFIAASTAYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEVAAIVKDGLRRMYGEAAPGEDPNVFYYLTVYNEPLPQPAKPA
VDGIEEGIVKGLYRFNTAESAGVTVAAANAPRIQLLGSGTAIHWALQAQKLLAEEWGVAA
DVWSATSWTELRRDALEADAALLRGEERVPYVRRALQGAEGPVLAVSDYMRQVPDQIAQW
VEQDYSSLGADGFGLSDTREAARRHFGVDAQSIVVAALAQLAKRGEVKATAVKEAREKYG
L
NT seq
2706 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgaatggcaggcctcgctggacgcggtcgccaaggctgccggcccgcac
cgtgcggcgttcctgatgcgccggacgctggagcgcgcggagggcaccggtgtcgcgctg
cccaagcttctcgagaccgactacgtcaacaccatcccgaccgccgccgagccgtccgtg
cccggtgacgaggcgatggagtcccgtatcaccgcgtggaaccgctggaacgcggccgcg
atggtgacccgcggctcgaaacacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctgtacgagaccggcttcaaccacttcttccgtggcaaggaggccgacggctcc
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccgcctcaccgagcagcacctcgacaacttccgccaggaggcgggcggcaacggc
ctgccgtcgtacccgcacccgcgccggctgccctggctgtgggagttccccaccgtctcc
atgggcctcggcccgctgtcggcgatctaccaggcgcgcttcaaccgctatctgacggcg
cgcggcatcaaggacgtctcgaactcccacgtctgggcgttcctcggcgacggcgagatg
gacgagccggagtccacggcggccctcgccctggcctcccgcgagggcctggacaacctg
accttcgtcatcaactgcaacctgcagcgcctcgacggcccggttcgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtcaagacgctg
tggggcacggcctgggacgagctgttccagctcgacaccacgggcgcgctcgtacgccgg
ctgcgcgaggtaccggacgcgcaggtgcagacgtatcagacccgcgacgccgcctacatc
cgccaggacttcttcggcgccgaccccgcgctcgtcgagatggccaggctgctgtccgac
gacaagatcctggagtgcttccacctctcccgcggtggccacgaggcccgcaaggtgtac
gcggcctacaaggcggcgctcgaccacaagggcgcgccgacggtcatcctggcccagacg
gtcaagggcttcacgctcggcgagggcttcgcgtcgaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaagaagatgcgggacctgctggagctgccgatcgcggac
agcgccttcgtcgacggcgtggtcccctacggccaccccggcgccgactccgccgaggtc
cgctacctccaggagcgccgggccgcgctgggcggtcccgccccggcccgccgtacgcac
gccctggcgccgctgcccgccccggccgagaaggcgttcgcctccttcgacaagggctcg
ggctcccagaacgtggccaccaccatggccttcgtccgtctgatcaaggacctggtccgc
gacaaggagacgggcaggcggtgggtgccgatcgtgccggacgaggcgcgcaccttcggc
atggagtcgctcttcccgtcgctcgggatctactcccccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaagaacggccagatcctcaacgag
gggatcacggaggccggttcgatggccgacttcatcgccgcgtccaccgcgtacgcgacg
cacggcgaggcgatgatcccgttctacatcttctactcgatgttcggctggcagcgcacc
gccgaccagatgtggcagctcggcgaccagctcggccgcggcttcctcgtcggcgcgacg
gcgggccgtacgacgctgacgggcgagggcctgcagcacgcggacggtcactcgccggtg
atcgcggcgacgaacccggcggcgctgacgtacgacccggcgttcgcctacgaggtcgcg
gcgatcgtcaaggacggtctgcgccgcatgtacggcgaggcggcgccgggtgaggacccg
aacgtcttctactacctcaccgtctacaacgagccgctgccgcagcccgccaagccggcc
gtggacggcatcgaagagggcatcgtcaagggcctgtaccgcttcaacaccgcggagtcg
gcgggcgtgaccgtggcggcggcgaacgccccgcgcatccagctgctcggctccggcacc
gcgatccactgggcgcttcaggcgcagaagctgctcgccgaggagtggggcgtggcggcc
gacgtctggtccgcgacgtcctggacggagctgcgccgggacgccctggaggcggacgct
gcgctgctgcgcggcgaagagcgggtcccgtacgtccgtcgggcgctgcagggcgcggag
ggcccggtgctggcggtctccgactacatgcgccaggtgcccgaccagatcgcccagtgg
gtcgagcaggactactcctccctcggcgccgacggcttcggcctctccgacacccgcgag
gcggcccgccgccacttcggcgtcgacgcccagtcgatcgtcgtcgcggccctggcccag
ctcgcgaagcggggcgaggtcaaggcgacggcggtcaaggaggcccgggagaagtacggc
ctgtaa
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