Streptomyces microflavus: SFUL_5103
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Entry
SFUL_5103 CDS
T02650
Name
(GenBank) Alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sfi
Streptomyces microflavus
Pathway
sfi00020
Citrate cycle (TCA cycle)
sfi00630
Glyoxylate and dicarboxylate metabolism
sfi00785
Lipoic acid metabolism
sfi01100
Metabolic pathways
sfi01110
Biosynthesis of secondary metabolites
sfi01120
Microbial metabolism in diverse environments
sfi01200
Carbon metabolism
sfi01210
2-Oxocarboxylic acid metabolism
Module
sfi_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sfi_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sfi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SFUL_5103
00630 Glyoxylate and dicarboxylate metabolism
SFUL_5103
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SFUL_5103
Enzymes [BR:
sfi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SFUL_5103
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SFUL_5103
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SFUL_5103
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SFUL_5103
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AGK79997
UniProt:
N0D419
LinkDB
All DBs
Position
complement(5632930..5636769)
Genome browser
AA seq
1279 aa
AA seq
DB search
MSSQSPSNSSISTDQASPGTNPAAAFGANEWLVDEIYQQYLQDPSSVDRAWWDFFADYKP
GTSGTADKPVPGAAASGAAATEAPAATPPAQAAAPAAAAPAPAKPAAAAPAAPAQAKPAE
AKPAEAKAAPAPAPAKPAAAKPAAAPAKADGATEAPAGPEYVTLRGPSAAVAKNMNASLE
LPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNYSFAV
KDGKPTLVKPEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARIG
KLGMDDFSGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLG
ISKVMTLTSTYDHRVIQGAASGEFLRVLSQLLLGQNDFYDEIFKALRIPYEPVRWLTDID
ASHDNDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLERDFA
VGGFAGKSMMKLRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERPRAQQPEREEQ
LRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAH
RGRLNVLANIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLA
ANPSHLEAVDPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLR
GYRTGGTVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLA
FEFRQAFNKDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGDI
TLEEAEQALQDFQGQLEKVFAEVREATSQPAAPHIPEPQAAFPVAVETAVSAEVVKRIAE
SQVNIPESITVHPRLMPQMQRRAASVENGTIDWGMGETLAIGSLLMEGTPVRLAGQDTRR
GTFGQRHAVLVDQVTGEDYTPLLYLTEEQARYNVYDSLLSEYAAMGFEYGYSLARPESLV
IWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQM
CAQDNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKIEEFTTGGFR
PVIGDASVKAEEVRKVVFCAGKLYYDLDAEREKRGDTETAIIRLERLYPLPGAEIQAEIA
KYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVG
SAKRHQAEQAQLVEEVFEA
NT seq
3840 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctcgaccgaccaagccagcccgggcacc
aacccggccgctgctttcggcgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggatcccagttcggtcgatcgcgcctggtgggacttcttcgccgactacaagccg
ggtacctccggcacggcggacaagcccgttcccggcgccgcagcctcgggggctgcggca
accgaggccccggccgccacccctccggcgcaagccgcggccccggccgctgccgcaccg
gccccggcgaagcccgccgccgctgctccggcagccccggcgcaggccaagccggccgag
gcgaagcccgccgaggccaaggccgctccggccccggctccggcgaagcccgctgcggcg
aagcccgctgccgcgcccgccaaggcggacggggccaccgaggccccggccggccccgag
tacgtgacgctgcgcggcccctcggccgccgtcgcgaagaacatgaacgcctcgctggag
ctgccgacggccacgtccgtccgcgcggtcccggtgaagctgctcttcgacaaccgcatc
gtcatcaacaaccacctcaagcgcgcccgcggcgggaagatctccttcacgcacctcatc
gggtacgcgatggtgcaggccctcaaggccatgccgtcgatgaactactccttcgcggtg
aaggacggcaagccgaccctggtgaagccggagcacgtcaacctcggcctcgccatcgac
ctggtgaagccgaacggcgaccgccagctggtcgtcgcggccatcaagaaggccgagacg
ctcaacttcttcgagttctggcaggcgtacgaggacatcgtccggcgcgcccgcatcggc
aagctcggcatggacgacttctccggcgtcaccgcctcgctgaccaaccccggcgggatc
ggcaccgtccactcggtgccccgcctgatgcccggacagggcctcatcatgggcgtcggc
gcgatggactacccggccgagttccagggcacctcgcaggacaccctcaacaagctcggt
atctcgaaggtcatgacgctcacgtcgacctacgaccaccgggtcatccagggcgcggcc
tccggcgagttcctgcgggtcctcagccagctgctgctcggccagaacgatttctacgac
gagatcttcaaggccctgcgcatcccgtacgagccggtccgctggctcacggacatcgac
gcgtcgcacgacaacgacgtgacgaaggccgcgcgggtcttcgagctgatccactcctac
cgggtccgcggccacgtcatggccgacaccgacccgctggagtaccgccagcgcaagcac
cccgacctcgacatcaccgagcacggcctcaccctgtgggaccttgagcgggacttcgcg
gtcggcgggttcgccggcaagtcgatgatgaagctccgcgacatcctcggtgtgctccgt
gagtcgtactgccgcaccaccggcatcgagttcatgcacatccaggacccgaagcagcgc
aagtggctccaggaccgggtggagcggccccgcgcccagcagcccgagcgcgaggagcag
ctgcgcatcctgcgccggctgaacgcggccgaggcgttcgagaccttcctgcagacgaag
tacgtcggtcagaagcggttctcgctggagggcggcgagtccgtcatcccgctgctcgac
gcggtcatcgactccgccgccgaggcccgcctcgacgaggtcgtcatcgggatggcccac
cgcggccgcctgaacgtgctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgg
gagttcgagggcaacctcgacccgcgctcgatgcacggctccggcgacgtcaagtaccac
ctgggcgccgagggcaccttcaccggtctggacggcgagcagatcaaggtctcgctggcc
gccaacccctcgcacctggaggcggtcgacccggtcctggagggcatcgcccgcgccaag
caggacatcatcaacaagggcggcacggacttcacggtcctgcccgtcgcgctccacggc
gacgcggccttcgcgggccagggcgtcgtcgccgagacgctcaacatgtcgcagctgcgc
ggctaccgcaccggcggcaccgtgcacgtggtgatcaacaaccaggtcggcttcaccgcc
gccccggagtcctcgcgctcctcgatgtacgccaccgacgtggcgcgcatgatcgaggcg
ccgatcatccacgtcaacggtgacgacccggaggccgtggtccgggtcgcgcggctcgcc
ttcgagttccggcaggcgttcaacaaggacgtcgtgatcgacctcatctgctaccgccgc
cgcggtcacaacgagggcgacaacccggagttcaccaacccgcagatgtacaccctgatc
gacaagaagcgctcggtgcgcaagctctacaccgagtccctcatcggtcgcggcgacatc
accctggaagaggcggagcaggcgctccaggacttccagggtcagctggagaaggtcttc
gccgaggtccgcgaggccacctcgcagccggccgccccgcacatcccggagccgcaggcc
gcgttcccggtcgccgtggagaccgcggtctccgccgaggtcgtgaagcggatcgccgag
tcccaggtcaacatccccgagtcgatcaccgtccacccccgtctgatgccgcagatgcag
cgtcgtgcggcctcggtggagaacggcacgatcgactggggcatgggcgagaccctggcc
atcggttcgctgctgatggagggcaccccggtccggctcgccggccaggacacccgccgc
ggcacgttcggccagcgccacgcggtgctggtggaccaggtcaccggcgaggactacacc
ccgctgctgtacctcaccgaggagcaggcccgctacaacgtctacgactcgctgctcagc
gagtacgcggcgatgggcttcgagtacggctactcgctggcccgtccggagtcgctggtc
atctgggaggcccagttcggtgacttcgtcaacggcgcccagaccgtcgtggacgagttc
atctcctcggccgagcagaagtggggccagacctccggcgtcacgctgctcctgccgcac
ggctacgagggccagggcccggaccactcgtccgcccgtcccgagcgcttcctccagatg
tgcgcgcaggacaacatgacggtcgcgatgccgaccctgccctcgaactacttccacctg
ctgcgctggcaggtgcacaacccgcaccacaagccgctcatcgtcttcaccccgaagtcg
atgctgcgtctgaaggcggcggcgtcgaagatcgaggagttcaccaccggcggtttccgt
ccggtgatcggcgacgcgtcggtcaaggcggaggaggtccgcaaggtcgtcttctgcgcg
ggcaagctctactacgacctggacgccgagcgggagaagcgcggcgacacggagaccgcg
atcatccggctggagcgcctgtacccgctgccgggtgcggagatccaggccgagatcgcc
aagtacccgaacgccgagaagtacctctgggcccaggaggagccggccaaccagggtgcg
tggccgttcatcgcgctcaacctgatcgaccacctggacctggccgtcggcgcggacgtg
ccgcacggcgagcgcctgcgccgcatctcgcggccgcacggctcgtccccggcggtcggc
tcggccaagcgtcaccaggcggagcaggcacagctggtcgaagaggtcttcgaggcctga
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