KEGG   Streptomyces ficellus: EIZ62_03850
Entry
EIZ62_03850       CDS       T06929                                 
Name
(GenBank) beta-ketoacyl-[acyl-carrier-protein] synthase family protein
  KO
K05551  minimal PKS ketosynthase (KS/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]
Organism
sfic  Streptomyces ficellus
Pathway
sfic00253  Tetracycline biosynthesis
sfic01056  Biosynthesis of type II polyketide backbone
sfic01100  Metabolic pathways
sfic01110  Biosynthesis of secondary metabolites
Module
sfic_M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:sfic00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    EIZ62_03850
   00253 Tetracycline biosynthesis
    EIZ62_03850
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:sfic01004]
    EIZ62_03850
   01008 Polyketide biosynthesis proteins [BR:sfic01008]
    EIZ62_03850
Enzymes [BR:sfic01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.235  tetracenomycin F2 synthase
     EIZ62_03850
    2.3.1.260  tetracycline polyketide synthase
     EIZ62_03850
Lipid biosynthesis proteins [BR:sfic01004]
 Polyketide synthase
  Component type
   EIZ62_03850
Polyketide biosynthesis proteins [BR:sfic01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Octaketide PKS
     EIZ62_03850
    Nonaketide PKS
     EIZ62_03850
    Decaketide PKS
     EIZ62_03850
SSDB
Motif
Pfam: ketoacyl-synt Ketoacyl-synt_C Thiolase_N
Other DBs
NCBI-ProteinID: QGV77477
UniProt: A0A6I6F990
LinkDB
Position
complement(881752..883017)
AA seq 421 aa
MRRVAITGLGVVAPGGVGVKEYWDLLTAGRTATRRITFYDPSPFRSQVAAECDFDPRAAG
LSPQEIRRLDRAAQFAVVSTREALADSGLDTSALDPGRIGTSLGSAVGCTTSLEREYVVV
SDGGRTWNVDHEYAVPELYRHFVPSSMAAEVGRAAGAEGPAAVVSTGCTSGLDSLGHAVD
LIREGTADVMIAGATEAPISPITSACFDAIHATTPRNDTPESACRPFDRTRSGLVLGEGA
AILVLEELESARRRGAHIYAEIAGFASRCNAYHMTGLKPDGREMAEAIDVALGEAALAPD
SVDYINAHGSGTKMNDRHETGAFKRSLGAHAYATPISSIKSMIGHSLGAIGSLEIAACAL
AMEHGVLPPTANLHEPDPELDLDYIPLTAREKKTDVVLSVGSGFGGFQSAMVLARPERRS
A
NT seq 1266 nt   +upstreamnt  +downstreamnt
atgcgcagagtcgccatcaccggcctgggcgtcgtggccccgggaggggtcggtgtcaag
gagtactgggacctgctcacggcgggacgcaccgccacccgcaggatcaccttctacgac
ccgtccccgttccgctcgcaggtcgccgccgagtgcgacttcgacccgcgggccgccggt
ctgtcgccgcaggagatccgccgcctcgaccgggccgcccagttcgcggtggtctccacc
cgcgaggcgctcgccgacagcggcctcgacacctccgcgctcgaccccgggcggatcggc
acctcgctgggcagcgcggtcggctgcaccaccagcctggagcgcgagtacgtggtggtc
agcgacggcggccgcacgtggaacgtcgaccacgagtacgccgtcccggagctgtaccgg
cacttcgtgcccagctccatggcggcggaggtcggccgggcggccggcgccgagggaccg
gccgccgtggtctccaccggctgcacctcgggactggactcgctcggccacgccgtcgac
ctgatccgcgagggcaccgccgacgtcatgatcgccggcgccaccgaggccccgatctcg
ccgatcacctcggcctgcttcgacgccatccacgccaccaccccccgcaacgacaccccc
gagagcgcctgccggcccttcgaccggacccgcagcggcctggtcctcggcgagggcgcg
gccatcctcgtcctggaggagttggagagcgcccggcggcgcggcgcccacatctacgcg
gagatcgcgggattcgcctcccgctgcaacgcgtaccacatgaccggactcaagcccgac
ggccgcgagatggccgaggccatcgacgtcgccctgggcgaggcggccctcgcgccggac
tcggtcgactacatcaacgcccacggctccggcaccaagatgaacgaccgtcacgagacg
ggcgccttcaagcgcagcctgggcgcccacgcctacgcgaccccgatcagctccatcaag
tcgatgatcgggcactccctcggcgcgatcggctccctggagatcgccgcctgcgccctg
gcgatggaacacggtgtgctgccgcccaccgccaacctccacgagcccgaccccgagctg
gacctcgactacatccccctgaccgcgcgcgagaagaagaccgacgtggtcctcagcgtc
ggcagcggcttcggcggcttccagagcgccatggtgctggcccgcccggagaggagaagc
gcatga

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