Streptomyces ficellus: EIZ62_24170
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Entry
EIZ62_24170 CDS
T06929
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sfic
Streptomyces ficellus
Pathway
sfic00010
Glycolysis / Gluconeogenesis
sfic00020
Citrate cycle (TCA cycle)
sfic00620
Pyruvate metabolism
sfic00785
Lipoic acid metabolism
sfic01100
Metabolic pathways
sfic01110
Biosynthesis of secondary metabolites
sfic01120
Microbial metabolism in diverse environments
sfic01200
Carbon metabolism
sfic01210
2-Oxocarboxylic acid metabolism
Module
sfic_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EIZ62_24170 (aceE)
00020 Citrate cycle (TCA cycle)
EIZ62_24170 (aceE)
00620 Pyruvate metabolism
EIZ62_24170 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EIZ62_24170 (aceE)
Enzymes [BR:
sfic01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EIZ62_24170 (aceE)
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
QGV80989
UniProt:
A0A6I6FNW7
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Position
complement(5357775..5360465)
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AA seq
896 aa
AA seq
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MTDPTRIQPSELDQLPDRDPEETAEWQASLDAVAKAAGPHRAAYLMRRTLERAEGAGLAL
PKLLETDYVNTIPTASEAGYGFDGDEEMEARITAWNRWNAAAMVSRGSKYGVGGHIATFA
SAAWLYETGFNHFFRGKEQDGSGDQLYIQGHASPGIYARAFLDGRLSEQHLDNFRQEAGG
NGLPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRNIKDVSNSHVWAFLGDG
EMDEPESTAALALAAREELDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVVK
SLWGTAWDELFQLDTTGALVRRLREVPDAQIQTYQTRDAAYIREDFFGKDPALAEMGRLL
SDDKIIECFQYSRGGHEPRKVFAAYKAALSHKGAPTVILAQTVKGFTLGKGFESKNANHQ
MKKLSVDEFKGMRDLLGLPISDSDFTDGQVPYGHPGADSPEVRYLQERRAALGGPAPARR
MHALDPLPAPADKTFAAFDKGSGSQSVATTMAFVRLMKDLIRDKQTGKRWVPIVPDEART
FGMESLFPSLGIYSPKGQTYEPVDRDQLMYYREAKDGQILNEGITEAGSMADFIAASTAY
STHGEQMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHS
PVIAATNPAALTYDPAFAYEVAVIVKDGLRRMYGETAPGEDPNVFYYLTVYNEPMPQPAK
PEGVDEGIVKGLYRFKEGTAPAADAPRLQLLSSGTAIHWALKAQDMLAADWGVTADVWSA
TSWSELRRDALEADAALLRGEERVPYVRQALADAQGPVLAVTDYMRQVPDQIAQWVEQDY
SSLGADGFGLSDTREAARRHFGVDAESVVVAALAQLAKRGEVPASLVKDARERYGL
NT seq
2691 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccacccgcatccagccgagcgagctcgaccagctgccggaccgcgacccc
gaggagaccgccgagtggcaggcgtccctcgacgccgtcgccaaggccgccgggccgcac
cgcgccgcgtacctgatgcgacgcaccctggagcgcgccgagggcgccggtctcgcgctg
cccaagctgctcgaaaccgactacgtgaacaccatccccaccgcctccgaggccggctac
ggcttcgacggcgacgaggagatggaagcgaggatcaccgcctggaaccgctggaacgcg
gccgccatggtctcccgcggctccaagtacggcgtcggcggccacatcgccaccttcgcc
tccgcggcctggctctacgagaccggcttcaaccacttcttccgcggcaaggagcaggac
ggctccggcgaccagctctacatccagggccacgcctcgcccggcatatacgcccgcgcc
ttcctcgacggccggctgtccgagcagcacctggacaacttccgccaggaggccggcggc
aacggcctgccgtcctacccgcacccccgccgcctgccctggctgtgggagttcccgacg
gtgtccatgggcctcggcccgctgtcggcgatctaccaggcgcggttcaaccgctacctg
accaaccgcaacatcaaggacgtctcgaactcccacgtgtgggcgttcctcggcgacggc
gagatggacgagcccgagtcgacggcggccctcgcgctcgccgcccgtgaggagctcgac
aacctcaccttcgtcatcaactgcaacctccagcgcctcgacggccccgtccgcgccaac
ttcaagatcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcgtgaag
tcgctgtggggcaccgcctgggacgagctgttccagctcgacaccaccggcgcgctggta
cgccggctgcgcgaggtgccggacgcgcagatccagacgtaccagacccgcgacgcggcc
tacatccgcgaggacttcttcggcaaggaccccgccctcgccgagatgggccggctgctg
tccgacgacaagatcatcgagtgcttccagtactcgcgcggcggccacgagccccgtaag
gtcttcgccgcgtacaaggccgccctctcgcacaagggcgcgccgaccgtgatcctcgcc
cagacggtgaagggcttcacgctcggcaagggcttcgagtccaagaacgccaaccaccag
atgaagaagctctcggtggacgagttcaagggcatgcgggacctgctgggcctgccgatc
tcggacagcgacttcaccgacggccaggtgccctacggccaccccggcgccgactccccc
gaggtccgctacctccaggagcgccgcgcggccctcggcggccccgccccggcgcgccgg
atgcacgcgctggacccgctgcccgcgccggccgacaagaccttcgccgccttcgacaag
ggctccggctcgcagtcggtcgcgacgaccatggcgttcgtccgtctgatgaaggacctg
atccgcgacaagcagaccggcaagcgctgggtgccgatcgtccccgacgaggcccgcacc
ttcggcatggagtcgctgttcccgtcgctcggcatctactcgccgaagggccagacgtac
gagccggtcgaccgcgaccagctgatgtactaccgcgaggccaaggacggccagatcctc
aacgagggcatcacggaggccggctcgatggccgacttcatcgccgcgtcgaccgcgtac
tccacgcacggcgagcagatgatcccgttctacatcttctactcgatgttcggctggcag
cggacggccgaccagatgtggcagctcggcgaccagctcgggcgcggcttcctcgtcggc
gccaccgccggccgcaccacgctgaccggtgagggcctccagcacgccgacggccactcc
cccgtcatcgcggcgacgaacccggcggcgctgacgtacgacccggcgttcgcctacgag
gtcgcggtgatcgtcaaggacggcctgcgccggatgtacggcgagacggcaccgggcgag
gacccgaacgtcttctactacctgaccgtctacaacgagccgatgccgcagccggccaag
cccgagggcgtggacgagggcatcgtcaagggcctgtaccgcttcaaggagggcaccgcc
ccggcggcggacgccccgcgcctccagctgctgtcctccggcacggcgatccactgggcg
ctcaaggcgcaggacatgctggccgccgactggggcgtgaccgccgacgtgtggtccgcg
acctcctggtcggagctgcggcgcgacgcgctggaggccgacgcggcgctgctgcgcggc
gaggagcgcgtgccgtacgtgcgccaggcgctggccgacgcgcagggcccggtgctggcg
gtcaccgactacatgcgccaggtcccggaccagatcgcgcagtgggtcgagcaggactac
agctcgctcggtgccgacgggttcggcctgtcggacacccgcgaggcggcccgccgccac
ttcggcgtggacgccgagtccgtggtggtcgccgcgctggcgcagctcgccaagcgcggt
gaggtcccggcctccctggtgaaggacgcccgcgagcgctacggcctgtag
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