KEGG   Streptomyces formicae: KY5_1460c
Entry
KY5_1460c         CDS       T05416                                 
Name
(GenBank) 5-methyltetrahydrofolate--homocysteine methyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
sfk  Streptomyces formicae
Pathway
sfk00270  Cysteine and methionine metabolism
sfk00450  Selenocompound metabolism
sfk00670  One carbon pool by folate
sfk01100  Metabolic pathways
sfk01110  Biosynthesis of secondary metabolites
sfk01230  Biosynthesis of amino acids
sfk04980  Cobalamin transport and metabolism
sfk04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:sfk00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    KY5_1460c
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    KY5_1460c
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    KY5_1460c
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    KY5_1460c
   04980 Cobalamin transport and metabolism
    KY5_1460c
Enzymes [BR:sfk01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     KY5_1460c
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: ATL26478
UniProt: A0A291Q4M2
LinkDB
Position
complement(1804517..1808080)
AA seq 1187 aa
MASSPTPSSQSAQAVQAAGTVDFPPESRARVEAFREALATRVVVADGAMGTMLQAQDPTL
EDFQNLEGCNEVLNITRPDIVRSVHEEYFAVGVDCVETNTFGANFAALSEYDIPERNFEL
SESGARIAREVADEFTASTGQQRWVLGSMGPGTKLPTLGHAPYTVLRDAYQINAEGMIAG
GADALLVETTQDLLQTKAAILGARRALDATGANLPVICSVTVETTGTMLLGSEIGAALTA
LEPLGIDMIGLNCATGPAEMSEHLRYLARHSRVPISCMPNAGLPVLGKNGAHYPLTAPEL
ADAQETFVREYGLSLVGGCCGTTPEHLRQVVERVRGVETSPREPRPEPGAASLYQSVPFR
QDTSYMAIGERTNANGSKKFREAMLEGRWDDCVEMARDQIREGAHMLDLCVDYVGRDGVK
DMAELAGRFATASTLPIVLDSTELPVLQAGLEKLGGRAVINSVNYEDSDGPESRFTKVTA
LAKEHGAALIALTIDEEGQARTAEHKVAIAERLIEDLTGNWGIHESDILIDTLTFTICTG
QEESRGDGIATIEAIRELKRRHPDVQTTLGLSNISFGLNPAARVLLNSVFLDECVKAGLD
SAIVHASKILPIARFDDEQVKVASDLIYDRREEGYDPLQKLMELFEGVSTKSMKAGKTEE
LLALPLDERLQRRIIDGEKNGLEADLDEALTGMPALDIVNTILLEGMKVVGELFGSGQMQ
LPFVLQSAEVMKSAVAHLEPHMEKSDAEGKGTIVLATVRGDVHDIGKNLVDIILSNNGYN
VVNLGIKQPVAAILDAAEEHSADVIGMSGLLVKSTVIMKENLEELNQRKMAADFPVILGG
AALTRAYVEQDLHEIYEGEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRVPSKA
TAAVLEADEDEGPARSDVAVDNPVPTPPFWGTRVVKGIQLKEYASWLDEGALFKGQWGLK
QARTGDGPSYEELVETEGRPRLRGWLDELHTKNMLEAAVVHGYFPCVSKGDDLIILNDDG
SERTRFSFPRQRRGRRLCLADFFRPEESGERDVVGFQVVTVGSKIGEATAELFAADSYRD
YLELHGLSVQLAEALAEYWHARVRTELGFGGEDPADVEDMFALKYRGARFSLGYGACPDL
EDRAKIAELLQPERIGVQLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3564 nt   +upstreamnt  +downstreamnt
atggcctcgtcgccaaccccgtcgtcgcagtccgcgcaggccgtacaggccgccgggaca
gtggacttcccgcccgagagcagggcccgagtcgaggccttccgcgaggccctcgccacc
cgtgtggtcgtggccgacggcgcgatgggcacgatgctccaggcgcaggaccccacgctc
gaggacttccagaacctcgaaggctgcaacgaagtcctcaacatcacccgacccgacatc
gtccgctcggtgcacgaggagtacttcgcggtcggcgtcgactgcgtggagaccaacacg
ttcggcgcgaacttcgccgccctgagcgagtacgacatccccgagcgcaacttcgagctc
tccgagtccggcgcccgcatcgcccgcgaggtcgccgacgagttcacggcgagcaccggg
cagcagcgctgggtgctcggctcgatgggccccggcaccaagctgccgacgctcggccac
gccccgtacacggtcctgcgcgacgcctaccagatcaacgccgagggcatgatcgccggc
ggcgccgacgcgctcctggtggagaccacccaggacctgctccagaccaaggccgcgatc
ctcggcgcccgccgcgcccttgacgccaccggcgcgaacctcccggtcatctgctcggtc
accgtcgagaccacgggcaccatgctcctcggctccgagatcggcgccgccctgaccgcg
ctggaaccgctcggcatcgacatgatcggcctgaactgcgccacgggcccggccgagatg
agcgagcacctgcgctacctcgcccgccactcgcgcgtcccgatctcctgcatgcccaac
gcgggccttccggtcctcggcaagaacggcgcgcactacccgctcaccgcgcccgagctc
gccgacgcccaggagaccttcgtacgcgagtacggcctgtccctggtcggcggctgctgc
ggcaccacgcccgagcacctgcgccaggtcgtcgagcgggtgcgcggcgtcgagacgagc
ccgcgcgagccgcgccccgagcccggcgccgcctcgctctaccagagcgtcccgttccgc
caggacacctcgtacatggcgatcggcgagcgcaccaacgccaacggctccaagaagttc
cgcgaggccatgctggagggccgctgggacgactgcgtggagatggcccgcgaccagatc
cgcgagggcgcccacatgctcgacctctgcgtcgactacgtgggccgcgacggcgtcaag
gacatggccgagctcgcgggccgcttcgccaccgcctccaccctgcccatcgtcctggac
tccaccgaactcccggtgctccaggccggactggagaagctcggcggccgcgccgtcatc
aactccgtcaactacgaggacagcgacggacccgagtcgcgcttcaccaaggtcaccgcg
ctcgccaaggagcacggcgccgcgctcatcgcgctgaccatcgacgaggagggccaggcc
cgcaccgccgagcacaaggtcgccatcgccgaacggctcatcgaggacctcacgggcaac
tggggcatccacgagtccgacatcctcatcgacaccctgaccttcaccatctgcaccggc
caggaggagtcgaggggcgacggcatcgccaccatcgaggcgatccgcgagctcaagcgc
cgccaccccgacgtgcagaccacgctcggcctctccaacatctccttcggcctcaacccg
gccgcccgcgtgctgctcaactccgtcttcctggacgagtgcgtcaaggcgggcctggac
tcggcgatcgtgcacgcctccaagatcctgccgatcgcgcgcttcgacgacgagcaggtg
aaggtcgcgagcgacctcatctacgaccgcagggaagagggctacgaccccctccagaag
ctcatggagctcttcgagggcgtctccaccaagtcgatgaaggcgggcaagaccgaggaa
ctcctcgccctgcccctggacgagcgcctccagcgccgcatcatcgacggcgagaagaac
ggcctggaagccgacctcgacgaggccctgacgggcatgcccgccctcgacatcgtcaac
accatcctcctggagggcatgaaggtcgtcggcgagctcttcggctccggacagatgcag
ctgccgttcgtgctccagtccgccgaggtcatgaagagcgcggtcgcccacctcgaaccg
cacatggagaagtccgacgcggagggcaagggcaccatcgtcctggccacggtccgcggc
gacgtccacgacatcggcaagaacctcgtcgacatcatcctgtcgaacaacggctacaac
gtggtcaacctcggcatcaagcagcccgtcgccgcgatcctggacgccgccgaggagcac
agcgcagacgtcatcggcatgtcaggactcctggtcaagtccaccgtgatcatgaaggag
aacctggaggagctcaaccagcgcaagatggcggccgacttcccggtgatcctcggcggc
gctgccctgacccgtgcgtacgtcgagcaggacctgcacgagatctacgagggcgaggtg
cgctacgcccgcgacgcgttcgagggcctgcgcctgatggacgccctcatcgccgtcaag
cgcggcgtgccgggcgcgaccctgcccgagctcaagcagcgccgcgtcccgagcaaggcg
accgcggccgtcctcgaggccgacgaggacgaggggcccgcccgttccgacgtcgccgtc
gacaacccggtccccacgccgccgttctggggcacccgcgtcgtcaagggcatccagctc
aaggagtacgcctcctggctcgacgagggcgccctcttcaagggccagtggggcctgaag
caggcacggaccggcgacggaccctcctacgaggaactcgtcgagaccgagggccgcccg
cgcctgcgcggctggctggacgagctgcacaccaagaacatgctcgaagcggccgtggtg
cacggctacttcccctgcgtgtccaagggcgacgacctgatcatcctcaacgacgacggc
tcggagcgcacccgcttctccttcccgcgccagcgccgcggccgccgcctgtgcctcgcc
gacttcttccgccccgaggagtctggtgagcgcgacgtcgtcggcttccaggtcgtcacc
gtcggctcgaagatcggcgaggccacggccgagctcttcgccgccgactcctaccgcgac
tacctcgaactgcacggcctgtccgtgcagttggccgaggcgctcgccgagtactggcac
gcgcgcgtgcgcaccgagctcggcttcggcggcgaggaccccgccgacgtcgaggacatg
ttcgccctgaagtaccgcggcgcccgcttctcgctcggctacggcgcctgccccgacctg
gaggaccgcgcgaagatcgccgagctgctccagccggagcgcatcggcgtgcagctctcc
gaggagttccagctgcaccccgagcagtccaccgacgcgatcgtcatccaccaccccgag
gcgaagtacttcaacgcgcgctga

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