Streptomyces formicae: KY5_2168
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Entry
KY5_2168 CDS
T05416
Name
(GenBank) Pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sfk
Streptomyces formicae
Pathway
sfk00010
Glycolysis / Gluconeogenesis
sfk00020
Citrate cycle (TCA cycle)
sfk00620
Pyruvate metabolism
sfk00785
Lipoic acid metabolism
sfk01100
Metabolic pathways
sfk01110
Biosynthesis of secondary metabolites
sfk01120
Microbial metabolism in diverse environments
sfk01200
Carbon metabolism
sfk01210
2-Oxocarboxylic acid metabolism
Module
sfk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
KY5_2168
00020 Citrate cycle (TCA cycle)
KY5_2168
00620 Pyruvate metabolism
KY5_2168
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
KY5_2168
Enzymes [BR:
sfk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
KY5_2168
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
ATL27186
UniProt:
A0A291Q6P7
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Position
2589774..2592470
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AA seq
898 aa
AA seq
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MTDPSAIQPSELDQLPDRDPEETAEWQASLDAVTQAAGPHRAAYLMRRTLERAEGAGLAL
PKLLETDYVNTIPTSAEPSIDGDEEMERKITAWNRWNAAAMVTRGSKHGVGGHIATFASA
AWLYETGFNHFFKGKEGDGSGDQLYIQGHASPGIYARAFLDGRLNEAQLDNFRQEAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPLSAIYQARFNRYLTNRGIKDVSASHVWAFLGDGEM
DEPESTAALALAAREGLDNLTYVINCNLQRLDGPVRANFRVVQELEAQFRGAGWNVIKIM
WGNAWDELFQLDTTGALVRRLREVPDAQFQTYATRDAAYIREHFFGAEPALAEMAKLLSD
DKISECFHLSRGGHEARKVYAAYRAALTHKGAPTVILAQTVKGFTLGKGFESKNANHQMK
KLSVDEFKDMRDLLGLPIPDSDFVDGQVPYGHPGADSPEVRYLQERRAALGGPAPARRTQ
PLAPLPAPAEKAFASFDKGSGTQSVATTMAFVRLVKDLVRDKESGKRWVPIVPDEARTFG
MESLFPSLGIYSPKGQTYEPVDRDQLMYYKEAKDGQILNEGITEAGSMADFIAASTSYAT
HGEAMIPFYIFYSMFGWQRTADQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALSYDPAFAYEVAAIVKEGLRRMYGEAAEGEDQNVFYYLTVYNEPMPQPAKPS
GVDEGIVKGLYRFNTAETAGLSPAANAARIQLLGSGTAIHWTLKAQRLLAEEWGVAADVW
SATSWTELRRDALEADEALLRGEERIPFVRKALEGAQGPVLAVSDYMRQVPDQIAQWVEQ
DYSSLGADGFGLSDTRDAARRHFGVDAESIVVAALAQLARRGEVPASAVKEARAKYGL
NT seq
2697 nt
NT seq
+upstream
nt +downstream
nt
atgaccgacccctccgcaatccagccgagcgagctcgaccagctcccggaccgcgacccc
gaggagaccgccgaatggcaggcctccctggacgccgtcacccaggcggccgggccgcac
cgtgccgcgtacttgatgcgccgcacgctggagcgcgccgagggcgcgggcctggcgctg
cccaagctgctcgagacggactacgtcaacaccatccccacctccgccgagccgtccatc
gacggtgacgaggagatggagcggaagatcaccgcgtggaaccgctggaacgcggccgcg
atggtgacccgtggctccaagcacggcgtcggcggccacatcgcgaccttcgcgtccgcg
gcctggctgtacgagaccggcttcaaccacttcttcaagggcaaggagggggacggcagc
ggcgaccagctgtacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccgcctgaacgaggcgcagctcgacaacttccggcaggaggcgggcggcaacggc
ctgccctcctacccgcacccgcgccgtctgccctggctgtgggagttcccgaccgtctcc
atggggctcggcccgctctccgccatctaccaggcgcgcttcaaccggtacctcaccaac
cgcggcatcaaggacgtctccgcctcgcacgtgtgggcgttcctcggcgacggcgagatg
gacgagcccgagtcgaccgcggccctcgcactggccgcgcgtgagggtctggacaacctc
acgtacgtcatcaactgcaacctgcagcgcctcgacggcccggtccgcgccaacttccgc
gtggtgcaggagcttgaggcccagttccgcggcgccgggtggaacgtcatcaagatcatg
tggggcaacgcctgggacgagctcttccagctcgacaccaccggcgccctggtccgccgc
ctgcgcgaggtgccggacgcgcagttccagacgtacgcgacgcgcgacgccgcgtacatc
cgcgagcacttcttcggcgccgagcccgcgctcgccgagatggcgaagctgctcagcgac
gacaagatcagcgagtgcttccacctctcgcgcggcggccacgaggcccgcaaggtctac
gcggcctaccgtgcggcgctcacccacaagggcgcgccgaccgtgatcctcgcgcagacg
gtcaagggcttcaccctcggcaagggcttcgagtccaagaacgccaaccaccagatgaag
aagctctcggtggacgagttcaaagacatgcgcgacctgctcggtctgccgatcccggac
agcgacttcgtcgacggccaggtgccctacggccaccccggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgcggccctcggcggccctgccccggcccgccgcacgcag
ccgctcgcgccgctgcccgcccccgccgagaaggcgttcgcctccttcgacaagggttcg
ggtacgcagtcggtggccacgaccatggcgttcgtacgcctggtcaaggacctcgtgcgc
gacaaggagtccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagtcgctcttcccctcgctcggcatctactcgcccaagggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaggccaaggacggccagatcctcaacgag
gggatcaccgaggccggttcgatggcggacttcatcgccgcttccacgtcgtacgcgacg
cacggcgaagcgatgatccccttctacatcttctactcgatgttcggctggcagcgcacc
gccgaccagatgtggcagctcggcgaccagctgggccgcggcttcctggtgggcgcgacg
gccggtcgcacgacgctgacgggtgagggtctgcagcacgcggacggccactcgccggtg
atcgcggcgaccaaccccgcggcgctctcgtacgacccggcgttcgcctacgaggtcgcg
gccatcgtcaaggagggcctgcgccgcatgtacggcgaggcggccgagggcgaggaccag
aacgtcttctactacctcaccgtctacaacgagccgatgccgcagcccgcgaagccctcg
ggcgtcgacgagggcatcgtcaagggcctgtaccgcttcaacacggccgagaccgccggg
ctttcgcccgccgccaacgccgcgcgcatccagctgctcggctccggcaccgcgatccac
tggacgctcaaggcgcagcggctgctcgccgaggagtggggcgtggccgccgacgtgtgg
tccgcgacgtcctggaccgagctgcggcgcgacgcccttgaggcggacgaggcgctgctg
cgcggcgaggagcgcatcccgttcgtccgcaaggcacttgaaggcgcgcagggcccggtg
ctcgccgtctccgactacatgcgccaggtccccgaccagatcgcgcagtgggtcgagcag
gactactcctcgctcggcgcggacggcttcggcctctccgacacgcgggacgcggcgcgc
cgtcacttcggtgtggacgccgagtcgatcgtcgtcgcggcgctcgcgcagctcgcccgc
cgcggtgaggtgcccgcttccgcggtgaaggaggcccgggccaagtacggcctgtaa
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