Streptomyces flavusporus: ACKTSN_04045
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Entry
ACKTSN_04045 CDS
T11144
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sflu Streptomyces flavusporus
Pathway
sflu00010
Glycolysis / Gluconeogenesis
sflu00020
Citrate cycle (TCA cycle)
sflu00620
Pyruvate metabolism
sflu00785
Lipoic acid metabolism
sflu01100
Metabolic pathways
sflu01110
Biosynthesis of secondary metabolites
sflu01120
Microbial metabolism in diverse environments
sflu01200
Carbon metabolism
sflu01210
2-Oxocarboxylic acid metabolism
Module
sflu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sflu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
ACKTSN_04045 (aceE)
00020 Citrate cycle (TCA cycle)
ACKTSN_04045 (aceE)
00620 Pyruvate metabolism
ACKTSN_04045 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ACKTSN_04045 (aceE)
Enzymes [BR:
sflu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
ACKTSN_04045 (aceE)
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Paralog
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
XLX04999
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Position
808020..810707
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AA seq
895 aa
AA seq
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MSDPTRPTESSATSELDQLPDRDAEETREWQASLDAVIRHAGPERAVYLLRRVHEYAARS
GVALPRLLSSDYINTIPASSQPVFPGDVAMESRITALNRWNAAAMVTRGSRLGLGGHIST
YASAAWLYEIGFNHFFKGKDGDGSGDQLYLQGHASPGIYARVFLEGRLREEQLNSFRREA
DGHGLPSYPHPRRLPWLWEFPTVSMGLGPLAAIYQARFNRYLHNRGIKDTSGSHVWAFLG
DGEVDEPESTAALELAAREGLDNLTFVVNCNLQRLDGPVRSNSKIVQELEARFRGAGWHV
VKTLWGEAWDPVLQQDTDGSLVRRLGEVPDAQLQTYAARDAAYIRKHFFTGDALSGLAAG
LSDAQLTDLFENSRGGHEPLKVYAAYKAAVEHRGGPTVVLAQTVKGHTLGPDFESRNANH
QMKKLTMAQFRQMRDALELPIPDSALSGDVVPFWHPGEDSEEVQYLRDRRSALAGPVPVR
RVVAKPLQQPPSGPFEALQKGFGKQEVATTMALVRLVKDLMRVEETGRRWVPIIPDEART
FGMESLFPTAGIYSPDGQTYEPVDVDQLLHYREAKDGQLIDEGITEAGSLAEFTAAATSY
ATHGEPMIPFYIFYAMFGFQRTGDQFWALADQLGRGFVVGATAGRTTMTGEGLQHADGHS
HLLASTNPAAVSYDPAFAYEIAVIVREGLRRMYGDQPEDIFYYLTVYNEPKQQPAMPTGP
SVEEGILRGIYRFRQAEPSDAGPRIQLLASGTAIHWALEAQELLMPQWGVQADVWSVTSW
TELRRDALNADRARLRGEECVPYVTRALSGAEGPVLAVSDWMRQVPDQISQWVEQDYSSL
GTDGFGLSDTRDAVRRYFRVDAESIVVAALDQLARAGAVHPATVVQARDRYGWQG
NT seq
2688 nt
NT seq
+upstream
nt +downstream
nt
atgagtgatccgactcggcccacagagtcctccgcgacgagtgagctcgaccagcttccc
gaccgtgacgccgaggaaacgagggaatggcaggcatcactcgacgctgtcatcaggcat
gccgggcccgaacgcgccgtgtacttgctgcggcgcgtgcacgagtacgcggccaggtcg
ggagtggccctcccgaggcttctgtcctcggactacatcaacacgatcccggcgtcgtcc
cagccggtcttcccgggcgacgtcgccatggagtcccgtatcaccgcgctgaacaggtgg
aacgcggccgcgatggtgacccgcggttcccgcctgggtctcggcggtcatatctcgacc
tacgcttcggcggcatggctctatgagatcggattcaaccacttcttcaagggcaaggac
ggggacggttccggggaccagctgtacctgcaggggcatgcctcgcccggcatctacgca
cgggtgttcctggaagggcgactgcgcgaggagcagctgaacagtttccggcgggaggcc
gacggtcacggcctgccgtcctacccgcacccccggcgcctgccgtggctgtgggagttt
ccgaccgtctcgatggggctcggccctcttgccgccatataccaggccagattcaaccgc
tatctgcacaaccggggcatcaaggacacgtccgggtcgcatgtatgggccttcctcgga
gacggggaagtggacgagcccgagtcgacggctgcgctggaacttgccgcccgtgagggc
ctcgacaacctcaccttcgtcgtcaactgcaacctgcagcggctggacggtccggtacgg
tcgaattccaagatcgtgcaggagctcgaggcgcggttccgcggcgcgggctggcatgtg
gtgaagactctctggggcgaggcctgggacccggtgctgcagcaggacaccgacggctcc
ctcgtccgccgcctcggcgaggtgcccgatgcccagctccagacgtacgccgcccgggac
gccgcctacatacgcaagcatttcttcaccggcgatgcgctgtccggccttgccgcaggt
ctgagtgacgcacagctcaccgacctgttcgagaactcccggggcggacacgaaccgctc
aaggtctacgccgcctacaaagccgcggtcgagcacaggggcgggcccaccgtcgtcctc
gcccagacggtgaagggtcacacgctgggtccggacttcgagtcccgcaacgccaaccat
cagatgaagaagctgaccatggcccagttccgtcagatgcgcgatgcgctggaactgccc
atcccggacagcgctctgagcggggacgtggtgccgttctggcacccgggtgaagactct
gaagaggtgcagtacctgcgtgaccgccgctcggctctggccggccccgtccccgtacgg
agggtggtggccaagccgctgcagcagccgccgtccggccccttcgaagccctccagaag
ggcttcggcaaacaggaggtggccaccaccatggcgctggtccggctggtcaaggacctg
atgcgcgtcgaggagacggggcggcgctgggtgcccatcatccccgatgaggcacgtaca
ttcggtatggaatccctgttcccgacggccgggatctactcgccggatggtcagacctat
gagccggtcgatgtcgatcagctactgcactacagggaggccaaggacggccagctcatc
gacgaaggcatcaccgaagccgggtcactggccgagttcaccgctgcggcgacgtcgtac
gccacacacggcgaacccatgatccccttctacatcttctatgccatgttcgggttccag
cgcacgggcgaccagttctgggccctggccgaccagttgggccgcggcttcgtcgtcggg
gcgacagccggccgtacgacgatgaccggcgagggactgcagcacgccgacgggcactcc
cacctgctggcgtccacgaatccggccgctgtcagctacgacccggccttcgcgtacgag
atcgcggtgatcgtcagggaaggcctgcgccggatgtacggcgaccagcccgaggacatc
ttctattacctgacggtctacaacgaacccaaacagcaaccggccatgcccaccgggccg
tcggtcgaggaagggatcctgcggggcatataccggttccggcaggcggagcccagcgac
gcaggaccacggatccagttgctggcctccggcactgccatccactgggcgctggaagcc
caggagcttctcatgccccaatggggagttcaggctgacgtctggtcagtgacgtcctgg
acggagctgcgccgcgatgcattgaatgccgacagggcgcggctgcgaggtgaggagtgc
gtcccgtatgtgacccgcgcgctgtcgggagccgaagggccggtgctggcggtcagcgac
tggatgcggcaggtgcccgatcagatcagccagtgggtcgagcaggactactcgtcgctg
ggaacggacggcttcggactgtcggacacccgcgatgccgtacgccgctatttccgagtg
gacgccgagtcgatcgtggttgccgccctggaccagttggcgcgggccggcgcagtccac
ccggcgacggttgtccaagcgcgcgatcgctacggctggcaggggtga
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