KEGG   Streptomyces fungicidicus: CNQ36_06970
Entry
CNQ36_06970       CDS       T07133                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
sfug  Streptomyces fungicidicus
Pathway
sfug00270  Cysteine and methionine metabolism
sfug00450  Selenocompound metabolism
sfug00670  One carbon pool by folate
sfug01100  Metabolic pathways
sfug01110  Biosynthesis of secondary metabolites
sfug01230  Biosynthesis of amino acids
sfug04980  Cobalamin transport and metabolism
sfug04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:sfug00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CNQ36_06970 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CNQ36_06970 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CNQ36_06970 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    CNQ36_06970 (metH)
   04980 Cobalamin transport and metabolism
    CNQ36_06970 (metH)
Enzymes [BR:sfug01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CNQ36_06970 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding Tautomerase_2
Other DBs
NCBI-ProteinID: AYL35190
UniProt: A0A494UKY0
LinkDB
Position
complement(1560135..1563647)
AA seq 1170 aa
MASLPLTPSADSRTRVSALREALASRVVVADGAMGTMLQAHDPTLADFENLEGCNEILNL
TRPDIVRSVHAEYFDAGVDCVETNTFGANLSALGEYDIAERVVELSEAGARIARETADEY
AARDGRARWVLGSMGPGTKLPTLGHTTFGAIRDAYQQNAEGLLAGGADALLVETTQDLLQ
TKASVVAARRAMETAGFEVPLIVSVTVETTGTMLLGSEIGAALTALEPLGIDMIGLNCAT
GPAEMSEHLRHLARHSRVQLSCMPNAGLPELTKDGARYPLSPGELADAQENFVRDYGLSL
VGGCCGTTPEHLRQLVERVRGLAPVERDPRPEPGAASLYQSVPFRQDTAYLAIGERTNAN
GSKKFREAMLEGRWDNCVELAREQIREGAHMLDLCVDYVGRDGVADMEELAGRFATASTL
PIVLDSTEVDVIRAGLEKLGGRAVINSVNYEDGDGPESRFARVTRLAQEHGAALIALTID
EEGQARTAEKKVEIAERLIDDLTGNWGIREEDILVDCLTFTICTGQEESRKDGVATIEGI
RELKRRHPKVQTTLGLSNISFGLNPAARILLNSVFLDECVKAGLDSAIVHASKILPIARF
SEEEVRTALDLIHDRRSEGYDPLQKLMALFEGATAKSLKAGKAEELAALPLEERLKRRII
DGERNGLEADLDEALQTRKALAIVNDTLLDGMKVVGELFGSGQMQLPFVLQSAEVMKTAV
AHLEPHMEKTDEAGKGTIVLATVRGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILE
AADEHRADVIGMSGLLVKSTVIMKENLEELNQRGLAADYPVILGGAALTRAYVEQDLHEI
YQGEVRYARDAFEGLRLMDALIGIKRGVPGAQLPELRQRRVRAAAVEIEERPEEGHVRSD
VATDNPVPTPPFRGTRVVKGIQLKEYASWLDEGALFKGQWGLKQARSGDGPSYEELAETE
GRPRLRGLLDRLQTENLLEAAVVYGYFPCVSKDDDLIVLDERGNERTRFTFPRQRRGRRL
CLADFFRPEESGETDVVGFQVVTVGSRIGEETARMFEANAYRDYLELHGLSVQLAEALAE
YWHARVRAELGFGGEDPAAMEDMFALKYRGARFSLGYGACPDLEDRAKIADLLEPERIGV
QLSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3513 nt   +upstreamnt  +downstreamnt
atggcctcgttgccgctgaccccttccgccgacagccggacccgtgtgtccgccctccgc
gaggcactcgcctcccgggtggtggtcgccgacggtgccatgggcaccatgctccaggca
cacgaccccaccctcgcggacttcgagaacctcgagggctgcaacgagatcctgaacctg
acccggccggacatcgtccgttcggtccacgccgagtacttcgacgccggagtcgactgc
gtcgagaccaacaccttcggcgccaacctctccgccctgggcgagtacgacatcgccgag
cgcgtcgtcgagctgtccgaggcgggcgcccgcatcgcccgtgagacggcggacgagtac
gccgcccgggacggccgcgcccgctgggtgctcggttcgatgggccccggcaccaagctg
cccaccctcggccacaccaccttcggcgccatccgcgacgcctaccagcagaacgccgag
ggcctgctcgccggcggcgccgacgccctgctggtggagacgacccaggacctgctgcag
accaaggcctccgtcgtggccgcccgccgcgcgatggagaccgccggcttcgaggtcccc
ctgatcgtctcggtcacggtggagaccaccggcaccatgctgctcggctccgagatcggc
gccgcgctcaccgcgctggaaccgctgggcatcgacatgatcggcctgaactgcgccacc
ggcccggccgagatgagcgagcacctgcgccacctcgcccgccactcccgcgtccagctg
tcgtgcatgccgaacgccggtctgccggaactcaccaaggacggcgcgcgctacccgctg
tccccgggagagctggcggacgcccaggagaacttcgtccgcgactacggcctgtccctc
gtgggcggctgctgcggcacgacgcccgagcacctgcggcagctcgtggagcgggtgcgc
ggcctggcccccgtcgagcgcgacccgcgtccggagcccggcgccgcctccctctaccag
agcgtccccttccgccaggacaccgcctacctggcgatcggcgagcgtacgaacgccaac
ggctcgaagaagttccgcgaggcgatgctcgagggccgctgggacaactgcgtggagctg
gcccgggagcagatccgcgagggcgcgcacatgctcgacctctgcgtggactacgtcggc
cgcgacggcgtcgccgacatggaggagctggcgggccggttcgccaccgcctccaccctg
cccatcgtcctggactccaccgaggtcgacgtcatccgggccgggctggagaagctcggc
ggccgcgcggtgatcaactcggtgaactacgaggacggcgacggaccggagtcccggttc
gcccgcgtcacccggctggcccaggagcacggcgccgcgctgatcgcgctgaccatcgac
gaggagggccaggcacgcaccgccgagaagaaggtcgagatcgcggaacggctgatcgac
gacctgaccggcaactggggcatccgtgaggaggacatcctcgtcgactgtctgaccttc
accatctgcaccggccaggaggagtcccgcaaggacggcgtcgccaccatcgagggcatc
cgcgagctgaagaggcgccacccgaaggtgcagaccacgctgggtctgtcgaacatctcc
ttcggcctcaacccggccgcccgcatcctgctgaactccgtcttcctcgacgagtgcgtc
aaggccggactggactcggcgatcgtgcacgcgtcgaagatcctgcccatcgcgcgcttc
agcgaggaggaggtccgcaccgccctcgacctcatccacgaccgccgcagcgagggctac
gacccgctgcagaagctgatggcgctcttcgagggcgccaccgcgaagtccctgaaggcg
ggcaaggccgaggaactggccgcgctgccgctggaggagcgcctcaagcgccgcatcatc
gacggcgagcgcaacggcctggaggccgacctggacgaggccctgcagacccgcaaggcc
ctcgccatcgtcaacgacaccctcctggacggcatgaaggtggtcggcgagctcttcggc
tccggccagatgcagctgccgttcgtgctccagtccgccgaggtgatgaagaccgcggtg
gcccacctcgagccgcacatggagaagaccgacgaggccggaaagggcaccatcgtgctc
gccacggtccgcggcgacgtgcacgacatcggcaagaacctggtcgacatcatcctgtcg
aacaacggctacaacgtcgtcaacctgggcatcaagcagccggtctccgcgatcctggaa
gccgccgacgagcacagggccgacgtcatcggcatgtccggcctgctggtcaagtccacc
gtgatcatgaaggagaacctggaggagctcaaccagcgcggcctggccgccgactacccg
gtgatcctgggcggtgccgccctcacccgcgcctacgtcgagcaggacctgcacgagatc
taccagggcgaggtccgctacgcccgcgacgccttcgagggcctgcgcctgatggacgcc
ctcatcggcatcaagcgcggtgtgcccggcgcccagctgccggaactgaggcagcgccgg
gtccgcgcggccgccgtcgagatcgaggagcgccccgaggaggggcacgtccgctccgac
gtcgccaccgacaacccggtccccaccccgcccttccggggcacccgcgtcgtcaagggc
atccagctcaaggagtacgcgagctggctcgacgagggcgccctcttcaagggccagtgg
ggcctgaagcaggcgcgcagcggcgacggaccgagctacgaggagctggccgagaccgag
ggacggcccaggctgcgcggactgctggaccggctccagacggagaacctgctggaggcc
gccgtggtctacggctacttcccgtgcgtctccaaggacgacgacctgatcgtcctggac
gagcggggcaacgagcgcacccgcttcaccttcccgcgccagcggcgcggccgccgtctg
tgcctggcggacttcttccgtccggaggagtccggcgagaccgacgtggtcggcttccag
gtcgtcaccgtgggctccaggatcggcgaggagaccgcccggatgttcgaggcgaacgcc
taccgcgactacctggagctgcacgggctgtccgtgcagctggcggaggccctcgccgag
tactggcacgcgcgggtccgcgccgagctgggcttcggcggtgaggacccggccgcgatg
gaggacatgttcgccctgaagtaccggggcgcccgcttctccctcggctacggcgcctgc
ccggacctggaggaccgggccaagatcgccgacctgctggagccggagcgcatcggcgtg
cagctgtccgaggagttccagctgcaccccgagcagtccacggacgccatcgtcatccac
cacccggaggcgaagtacttcaacgcccgctga

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