Streptomyces fungicidicus: CNQ36_09740
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Entry
CNQ36_09740 CDS
T07133
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
sfug
Streptomyces fungicidicus
Pathway
sfug00010
Glycolysis / Gluconeogenesis
sfug00020
Citrate cycle (TCA cycle)
sfug00620
Pyruvate metabolism
sfug00785
Lipoic acid metabolism
sfug01100
Metabolic pathways
sfug01110
Biosynthesis of secondary metabolites
sfug01120
Microbial metabolism in diverse environments
sfug01200
Carbon metabolism
sfug01210
2-Oxocarboxylic acid metabolism
Module
sfug_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
sfug00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CNQ36_09740 (aceE)
00020 Citrate cycle (TCA cycle)
CNQ36_09740 (aceE)
00620 Pyruvate metabolism
CNQ36_09740 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CNQ36_09740 (aceE)
Enzymes [BR:
sfug01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CNQ36_09740 (aceE)
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Paralog
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Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF3135
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AYL35698
UniProt:
A0A494V0V4
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Position
2156687..2159389
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AA seq
900 aa
AA seq
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MTDPNAIQPSELDQLPDRDPEETAEWQASLDAVTEAAGPHRAAYLMRRTLERAEGAGLAL
PKLLETDYVNTIPTAAEPAVDGDEAMEQRITAWNRWNAAAMVTRGSKYGVGGHIATFASA
AWLYETGFNHFFRGKEGDGSGDQLYIQGHASPGIYARAFLDGRIDEAQLDNFRREAGGNG
LPSYPHPRRLPWLWEFPTVSMGLGPISAIYQARFNRYLTSRGIKDVSDSHVWAFLGDGEM
DEPESTTALTLASREQLDNLTFVINCNLQRLDGPVRANFKIVQELEAQFRGAGWNVIKTL
WGTAWDELFRLDTTGALVRRLREVPDAQVQTYQTRDAAYIRQDFFGKDPALAEMAKLLSD
DKILECFHLSRGGHESRKVYAAYKAALAHKGAPTVILAQTVKGHTLGEGFASKNANHQMK
KLTVDEFKAMRDRLELPVSDAQFVDGVVPYVHPGADSPEVRYLQERRAALGGPAPARRVH
PVAPLPQPADKAFAAFDKGSGSQNVATTMAFVRLVKDLVRDKETGKRWVPIVPDEARTFG
MESLFPSLGIYSPMGQTYEPVDRDQLMYYKEAKNGQIFNEGITEAGAMAEFVAASTSYST
HGETMIPFYIYYSMFGWQRTGDQMWQLGDQLGRGFLVGATAGRTTLTGEGLQHADGHSPV
IAATNPAALTYDPAFAYEIGVIVKEGLRRMFGEAGPDEDQNVFYYLTVYNEPLPQPAKPS
AAGIDEGIVKGLYRFNTAESAGVSPAANAPRIQLLGSGTAIHWALKAQRLLAEEWGVAAD
VWSATSWTELRRDAMEADEALLRGEERVPFVQQALQGAEGPVLAVSDYMRQVPDQIAQWV
EQDYSSLGADGFGLSDTRDAARRHFGVDAESIVVAALAQLARRGEVQAAAVKEAREKYGL
NT seq
2703 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaccccaacgccatccagccgagcgagctcgatcagctcccggaccgcgacccc
gaggagaccgccgagtggcaggcctccctggacgccgtcaccgaggcggccgggccgcac
cgtgccgcgtacctgatgcgccgcacgctggagcgtgccgagggcgccggcctcgcgctg
cccaagctgctcgagaccgactacgtcaacaccatccccaccgccgccgagcccgccgtg
gacggcgacgaggcgatggagcagcggatcaccgcgtggaaccgctggaacgcggcggcg
atggtgacccgcggcagcaagtacggcgtcggcggccacatcgccaccttcgcctccgcg
gcctggctctacgagaccggcttcaaccacttcttccgcggcaaggaaggcgacggctcg
ggcgaccagctctacatccagggccacgcctcccccggcatctacgcccgcgccttcctc
gacggccggatcgacgaggcgcagctcgacaacttccgccgcgaggccgggggcaacgga
ctgccgtcgtacccgcacccgcggcgtctgccctggctgtgggagttccccaccgtgtcg
atgggcctcggcccgatctccgcgatctaccaggcgcggttcaaccgctatctgaccagc
cgcggcatcaaggacgtctccgactcgcacgtctgggcgttcctcggcgacggcgagatg
gacgagcccgagtcgacgaccgcgctcaccctcgcctcccgcgagcagctggacaacctc
accttcgtcatcaactgcaacctgcagcgcctcgacggaccggtccgcgccaacttcaag
atcgtgcaggagctggaggcccagttccgcggcgccggctggaacgtcatcaagaccctg
tggggcacggcctgggacgagctgttccggctcgacaccaccggcgccctggtacgccgg
ctccgcgaggtgcccgacgcgcaggtgcagacgtaccagacgcgcgacgccgcctacatc
cgccaggacttcttcggcaaggacccggcgctcgccgagatggcgaagctgctcagcgac
gacaagatcctcgagtgcttccacctctcccgcggcggccacgagtcccgcaaggtgtac
gccgcctacaaggccgcgctcgcccacaagggcgcgccgaccgtgatcctcgcgcagacc
gtcaagggccacaccctcggtgagggcttcgcctccaagaacgccaaccaccagatgaag
aagctgacggtggacgagttcaaggcgatgcgcgaccggctggaactgccggtctccgac
gcgcagttcgtcgacggcgtggtgccctacgtgcacccgggcgccgactcccccgaggtc
cgctacctccaggagcgccgcgccgccctcggcggtccggccccggcccgccgcgtgcac
ccggtcgcgccgctgccgcagcccgccgacaaggcgttcgccgccttcgacaagggctcc
ggctcgcagaacgtcgccaccaccatggccttcgtccgcctggtcaaggacctcgtccgc
gacaaggagaccggcaagcgctgggtgccgatcgtccccgacgaggcgcgcaccttcggc
atggagagcctcttcccgtccctcggcatctactcgccgatgggccagacgtacgagccg
gtcgaccgcgaccagctgatgtactacaaggaagccaagaacggccagatcttcaacgag
ggcatcaccgaagccggtgccatggccgagttcgtcgccgcctccacgtcgtactcgacg
cacggcgagacgatgatcccgttctacatctactactcgatgttcggctggcagcgcacc
ggcgaccagatgtggcagctcggcgaccagctcggccgcggcttcctggtcggcgccacc
gccggccgcaccacgctgacgggcgagggcctgcagcacgccgacggccactccccggtc
atcgcggcgaccaacccggcggcactgacgtacgacccggcgttcgcgtacgagatcggc
gtcatcgtcaaggagggtctgcgccggatgttcggcgaggccgggccggacgaggaccag
aacgtcttctactacctgacggtctacaacgagccgctgccgcagcccgccaagccgtcg
gcggccggcatcgacgagggcatcgtcaagggcctgtaccgcttcaacacggcggagtcc
gcgggcgtctccccggccgcgaacgcgccgcggatccagctgctgggctccggcacggcg
atccactgggccctgaaggcgcagcggctgctcgccgaggagtggggcgtggccgccgac
gtgtggtccgccacctcgtggaccgagctgcgccgcgacgccatggaggccgacgaggcg
ctgctgcggggcgaggagcgggtgccgttcgtccagcaggcgctgcagggcgccgagggc
ccggtgctggcggtctcggactacatgcgccaggtcccggaccagatcgcgcagtgggtc
gagcaggactactcgtcgctgggcgccgacggcttcggtctgtcggacacccgtgacgcc
gcccgccgccacttcggcgtggacgccgagtccatcgtcgtcgcggccctggcccagctc
gcccggcgcggcgaggtgcaggcggcggccgtgaaggaagcccgcgagaagtacggcctg
taa
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