Sorex fumeus (smoky shrew): 130015938
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Entry
130015938 CDS
T10594
Symbol
DOCK1
Name
(RefSeq) dedicator of cytokinesis protein 1 isoform X1
KO
K13708
dedicator of cytokinesis protein 1
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04148
Efferocytosis
sfum04510
Focal adhesion
sfum04666
Fc gamma R-mediated phagocytosis
sfum04810
Regulation of actin cytoskeleton
sfum05100
Bacterial invasion of epithelial cells
sfum05135
Yersinia infection
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
130015938 (DOCK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
130015938 (DOCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
130015938 (DOCK1)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
130015938 (DOCK1)
09160 Human Diseases
09171 Infectious disease: bacterial
05135 Yersinia infection
130015938 (DOCK1)
05100 Bacterial invasion of epithelial cells
130015938 (DOCK1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
sfum04131
]
130015938 (DOCK1)
Membrane trafficking [BR:
sfum04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
130015938 (DOCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TPR_DOCK
DOCK_N
DOCK-C2
DHR-2_Lobe_C
DHR-2_Lobe_A
DHR-2_Lobe_B
SH3_1
SH3_9
SH3_2
SR-25
Motif
Other DBs
NCBI-GeneID:
130015938
NCBI-ProteinID:
XP_055962645
LinkDB
All DBs
Position
Unknown
AA seq
1886 aa
AA seq
DB search
MTRWVPTKREEKYGVAFYNYDARGADELSLQIGDTVHILETYEGWYRGYTLRKKSKKGIF
PASYIHLKDAIVEGKGQHETVIPGDLPLIQEVTSTLREWSTIWRQLYVQDNREMFRSVRR
MIYELMDWRSQILSGTLPQDELKELKKKVTAKIDYGNRILDLDLVVRDEDGNILDPELTS
TISLFRAHEIASRQVEERLQEEKSQKQNMDVNRQARFAATPSLALFVNLKNVVCKIGEDA
EVLMSLYDPVESKFISENYLVRWSSSGLPKDIDRLHNLRAVFTDLGSKDLKRDKISFVCQ
IVRVGRMELRESNTRKLTSGLRRPFGVAVMDVTDIINGKVDDEDKQHFIPFQPLALDDAI
RHKPLNMSSRFSPRVAGENDFLQTVINKVIAAKEVNHKGQGLWVTLKLLPGDIHQIRKEF
PHLVDRTTAVARKTGFPEIIMPGDVRNDIYVTLVQGDFDKGSKTTAKNVEVTVSVFDEEG
KRLEHVIFPGAGDDAISEYKSVIYYQVKQPRWFETVKVAIPIEDVNRSHLRFTFRHRSSQ
DSKDKSEKIFALAFVKLMRYDGTTLRDGEHDLIVYKAEAKKLEDASTYLSLPSTKAELEE
KGHSATGRSMQSLGSCAISKDSFQIATLVCSTKLTQNVDLLGLLKWRSNTSALQQNLRQL
MKVAGGEVVKFLQDTLDALFNIMMENSESETFDTLVFDALVFIIGLIADRKFQHFNPVLE
TYIKKHFSATLAYMKLTKVLRDYVDNAEKPGVGEQLLRAVESLEYIFKFIVRSRVLFNQL
YENKGEADFVESLLQLFRSINTMMSSASDQTLRVKCAALKYLPTIVNDVKLVFDPKELSK
MFTDFILNVPAGLLTIQKLYCLIEIIHSDLFTQHDCREILLPVMTDQLKYHLERQEDLEA
CCQLLSTILEVLYRKDVGPTARHVQVIMEKLLRTVNRTVISLGRDSQLIGNFVACMTAIL
RQMEDYHYAHLIKTFGKMRTDVVDFLMETFIMFKNLIGKNVYPFDWVIMNMVQNKVFLRA
INQYADMLNKKFLDQANFELQLWNNYFHLAVAFLTQESLQLENFSSAKRTKILNKYGDMR
RQIGFEIRDMWYNLGQHKIKFIPEMVGPILEMTLIPETELRKATIPIFFDMMQCEFHSTR
SFQMFENEIITKLDHEVEGGRGDEQYKVLFDKILLEHCRKHKYLAKTGETFVRLVVRLME
RLLDYRTIMHDENKENRMSCTVNVLNFYKEIEREEMYIRYLYKLCDLHKECDNYTEAAYT
LLLHAKLLKWSEDVCAAHLTQRDGYQATTQGQLKEQLYQEIIHYFDKGKMWEEAITLGKE
LAEQYENELFDYEQLSELLKKQAQFYENIVRVIRPRPDYFAVGYYGQGFPSFLRGKVFIY
RGKEYERREDFEARLLTQFPNAEKMKTTSPPGEDIKNSPGQYIQCFTVKPKLDLPPKFHR
PVSEQILSFYRVNEVQRFEYSRPIRKGEKNPDNEFANMWLERTIYTTAYKLPGILRWFEV
KSVFMVEVSPLQNAIETMQLTNDKMKSMVQQHLGDPSLPINPLSMLLNGIVDPAVMGGFA
NYEKAFFTEHYLQEHPDALENIEKLKDLIAWQIPFLAEGIRIHGDKVTEALRPFHERMET
CFRLLKEKVEKQYGVRTLPSCLDDRRGSRPHSMVRSFTMPSSSRPLSVASVSSLSSDSTP
SRPGSDGFALEPLLPKKMHSRSQDKLDKDEPEKDKKEKKKEKRNSKHQELLDKDLKAADS
PTPQSEAVILSETISPLRPQRPKSQVINVIGSERRFSVSPSSPTSQQTPPPVTPRAKHSF
SLQSSLELNGMSGADMAEVPPPLPLKGSMADYGNVMDSPEGAGPPLPPPPPPHQRHLPPP
LPSKTPPPPPPKTTRKQTSVDSGIVQ
NT seq
5661 nt
NT seq
+upstream
nt +downstream
nt
atgacgcgctgggtgcccaccaagcgcgaggagaaatacggcgtggcgttttataactat
gacgcccggggagccgatgagctgtccctgcagatcggggacaccgtgcacattctggag
acctatgagggctggtaccgaggctacaccttacggaagaagtccaagaagggcatcttt
cctgcctcgtacatccacctcaaggatgccatcgtggagggcaaagggcaacatgagacc
gtcatccccggggacctcccgctcatccaggaggtcaccagcaccctccgggagtggtcc
accatctggaggcagctctacgtgcaagacaaccgggagatgttccgtagcgtccgccgc
atgatctacgagctgatggactggcgctcgcagatcctgtccgggacgctgccgcaggat
gagctcaaggagctgaagaagaaggtcactgccaagatcgattatggaaacagaattctg
gacctggacctggtggtaagagatgaagatgggaacattctggacccagaactcacgagc
accatcagtctcttccgggcgcatgaaatcgcctcgagacaagtggaggagagactgcag
gaggaaaagtcgcagaagcagaacatggacgtcaaccgacaagccaggtttgcggccacc
ccatcgctggccttgttcgtcaacctcaaaaacgtggtttgtaagatcggagaagacgcg
gaggtgctcatgtcgctgtacgaccccgtggagtccaagttcatcagcgagaactacctg
gtgcgctggtccagctcgggcctgcccaaggacatcgaccggctgcacaacctgcgtgcc
gtcttcacggacctgggcagcaaggacctgaagcgcgacaagatcagcttcgtgtgccag
atcgtgcgcgtgggccgcatggagctgcgggagagcaacactcgcaagctgacctcgggg
ctgcggcggcccttcggcgtggctgtgatggacgtcacagatataataaacggaaaagta
gacgatgaggataaacagcatttcattcccttccagccgctcgcgttggacgacgccatt
cgacacaagccgctgaacatgtcatcccgtttctcacccagggtggcaggggagaatgac
ttcctccagactgtcataaacaaagtcattgctgccaaagaagtcaaccacaagggccag
ggtctgtgggtaactctgaaattgctccctggagatatccaccagatcaggaaggagttt
ccacacctggtggacaggaccacggcggtggcccgcaagacgggcttcccggagatcatc
atgccgggtgacgtccggaacgacatctacgtgaccttggtccagggcgattttgacaaa
gggagtaaaaccacggccaagaacgtggaggtgacggtgtctgtgttcgacgaggagggg
aagcgactggagcacgtgatcttcccgggggccggcgacgacgcgatttccgagtacaag
tctgtgatttactaccaggtcaagcagccgcgctggttcgagaccgtgaaggtggccatc
cccatcgaggacgtgaaccgcagtcacctccgcttcaccttccgccatcgctcctcccag
gactcaaaggacaagtccgagaagatcttcgctctcgccttcgtgaagctcatgcgttac
gacgggaccacgctcagggacggggagcacgacctcatcgtctacaaggccgaggccaag
aagctggaagacgcgtccacgtacctgagcctgccgtccaccaaggccgagctggaggag
aaggggcactcggccacgggccggagcatgcagagcctgggcagctgtgccatcagcaag
gactccttccagatcgccacattggtgtgttccaccaagctgacccagaacgtggacctg
ctgggcctccttaagtggcgttccaacaccagcgccctgcagcagaacctgcggcagctc
atgaaggtggccggcggcgaggtggtgaagttcctgcaggacacgctggacgccctcttc
aacatcatgatggagaactcggagagcgagaccttcgacacgctggtgttcgacgcactg
gtatttatcatcggcctcattgcagacagaaaattccagcatttcaaccctgttctggag
acgtacattaagaagcacttcagcgcgacgttggcctacatgaagctgacgaaagtcctg
agggactacgtggacaacgccgagaagccgggcgtcggcgagcagctgctcagagccgtg
gagtcgctggagtacatcttcaagttcatcgtgcgctcccgcgtcctcttcaaccagttg
tacgagaacaaaggcgaggccgacttcgtggaatccctactgcagctgttccggtccatc
aacaccatgatgagcagcgcctcggaccagaccctgcgggtgaagtgcgcggcgctcaag
tacttgcccacgatcgtcaatgatgtgaagctggtgtttgaccccaaggagctcagcaaa
atgttcactgacttcatcctcaacgtgcccgcgggtttgctgaccatccagaagttgtac
tgcttgatcgagatcatccacagcgacctcttcacccagcacgactgcagagagatcctg
ctgcccgtgatgaccgaccagctcaagtaccacctggagcggcaggaagacctggaggcc
tgttgccagctgctcagcaccatcctggaggtgctgtaccggaaggacgtgggcccgacc
gcccggcacgtccaggtcatcatggagaagctgctgcgcacggtgaaccggacggtcatc
tcgctgggccgggactcgcagctcatcgggaacttcgtagcctgcatgacggcgatttta
cggcaaatggaagattatcactatgcccatttgatcaagactttcgggaaaatgaggacg
gacgtggtggacttcctcatggagacgttcatcatgtttaagaacctgattgggaagaac
gtctacccgttcgactgggtcatcatgaacatggtgcagaataaagtcttcctgcgagca
attaatcagtatgcagatatgctgaacaaaaaatttctggatcaagccaattttgagctg
cagctgtggaacaactacttccacctggccgtggccttcctcacccaggagtccctgcag
ctggagaacttctcgagcgccaagagaaccaagatcctcaacaagtacggagacatgagg
agacagatcggcttcgagatcagagacatgtggtacaaccttggtcaacacaagatcaag
ttcatacccgagatggtgggccccatcctggagatgacgcttatccccgagacggagctg
cgcaaggccaccatccccatcttcttcgacatgatgcagtgcgagttccactcaacccga
agcttccagatgtttgaaaatgagatcatcaccaagctggatcatgaagtggagggaggc
cgcggcgacgagcagtacaaagtgttatttgataaaatcctcctggagcactgccggaag
cacaagtacctggccaagaccggggagaccttcgtgcggctggtggtgcggctcatggag
cggctgctggactacaggaccatcatgcacgacgagaacaaggagaaccgcatgagctgc
accgtcaacgtgctgaatttctacaaggaaattgagagagaagaaatgtacatcaggtac
ctctacaagctgtgtgacctgcataaagagtgcgacaactacacagaggccgcctacacc
ctgctgctccacgccaagctcctgaagtggtcggaggacgtgtgcgcggcccacctcacg
cagcgcgacggctaccaggccaccacgcagggtcagctgaaggagcagctgtaccaggag
atcatccactacttcgacaaaggcaagatgtgggaagaggccatcacgctgggcaaggag
cttgcagaacagtatgaaaacgaactcttcgactacgagcagctcagcgagctcctgaag
aagcaggcacagttctacgagaacatcgtccgcgtcatccggccccggcccgactacttc
gccgtcggctactacggacagggcttcccctccttcctgcggggcaaagtcttcatctac
cgcgggaaggagtatgagcgcagagaagacttcgaggcccgcctgctgactcagtttccc
aacgcagagaagatgaagacgacgtcgccgcccggagaggacatcaagaactcccctgga
cagtacattcagtgcttcaccgtcaaacccaaactggacttgccccccaaattccaccgg
cctgtgtccgagcagatcctcagcttctacagggtgaacgaggtccagcgatttgaatat
tcccggccaatccgcaagggagagaaaaacccagacaacgaatttgcgaacatgtggctg
gagagaaccatctacaccaccgcctacaagctccctggcatcctgaggtggtttgaagtc
aaatcggttttcatggtggaggtcagccctctgcagaacgccatcgagaccatgcagctg
accaacgacaagatgaagagcatggtccagcagcacctgggggaccccagcctgcccatc
aaccccctctccatgctgctcaatggcatcgtggaccccgctgtcatgggcggcttcgcc
aactacgagaaggccttcttcacggagcactacctgcaggagcaccccgacgccctcgag
aacattgagaaactcaaggacctgatcgcctggcagatcccgtttctggctgagggcatc
aggatccacggggacaaggtgacggaggcactgcggccgttccacgagaggatggagacc
tgcttccggctgctgaaggagaaggtggagaaacagtacggcgtgcgcaccctgccgtcc
tgcctggatgaccgtcggggcagccgcccacactccatggtccgctcgttcaccatgccg
tcctcgtcccggccgctgtcggtggcctccgtctcgtcgctgtcctcggacagcacgccg
tccaggcccggctctgatgggtttgccctggagccgctcctgcccaagaaaatgcactcc
cggtcccaggacaagctggacaaggatgagcccgagaaggacaagaaggagaagaagaag
gagaagaggaacagcaagcaccaggagctgctggacaaggacctcaaggcggccgacagc
cccacgccgcagtccgaggccgtgatcctctcggaaacgataagccccctgcggccccag
agacccaagagccaagtgatcaacgtcatcgggagcgagaggcgcttctcagtgtccccg
tcgtcgcccacctcacagcagacgccccctccggtcacgcccagggccaagcacagcttc
agtctgcagtccagcctggagctgaacggcatgagcggggcggacatggccgaggtgccc
ccacctctgcccctcaaaggcagcatggccgactacgggaacgtgatggacagccccgag
ggggcgggcccgcccctgcccccgcccccaccgccgcaccagaggcatctgccgccgccg
ctgcccagcaaaacgccgccacctcccccgccaaagacgacacgcaagcagacttccgtg
gactcgggcatcgtgcagtga
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