Sorex fumeus (smoky shrew): 130020311
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Entry
130020311 CDS
T10594
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum01522
Endocrine resistance
sfum04012
ErbB signaling pathway
sfum04062
Chemokine signaling pathway
sfum04148
Efferocytosis
sfum04151
PI3K-Akt signaling pathway
sfum04360
Axon guidance
sfum04370
VEGF signaling pathway
sfum04510
Focal adhesion
sfum04517
IgSF CAM signaling
sfum04518
Integrin signaling
sfum04670
Leukocyte transendothelial migration
sfum04810
Regulation of actin cytoskeleton
sfum04935
Growth hormone synthesis, secretion and action
sfum05100
Bacterial invasion of epithelial cells
sfum05135
Yersinia infection
sfum05146
Amoebiasis
sfum05163
Human cytomegalovirus infection
sfum05165
Human papillomavirus infection
sfum05170
Human immunodeficiency virus 1 infection
sfum05200
Pathways in cancer
sfum05202
Transcriptional misregulation in cancer
sfum05205
Proteoglycans in cancer
sfum05208
Chemical carcinogenesis - reactive oxygen species
sfum05222
Small cell lung cancer
sfum05417
Lipid and atherosclerosis
sfum05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
130020311 (PTK2)
04370 VEGF signaling pathway
130020311 (PTK2)
04151 PI3K-Akt signaling pathway
130020311 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
130020311 (PTK2)
04518 Integrin signaling
130020311 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
130020311 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
130020311 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
130020311 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
130020311 (PTK2)
04062 Chemokine signaling pathway
130020311 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
130020311 (PTK2)
09158 Development and regeneration
04360 Axon guidance
130020311 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
130020311 (PTK2)
05202 Transcriptional misregulation in cancer
130020311 (PTK2)
05205 Proteoglycans in cancer
130020311 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
130020311 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
130020311 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
130020311 (PTK2)
05163 Human cytomegalovirus infection
130020311 (PTK2)
05165 Human papillomavirus infection
130020311 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
130020311 (PTK2)
05100 Bacterial invasion of epithelial cells
130020311 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
130020311 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
130020311 (PTK2)
05418 Fluid shear stress and atherosclerosis
130020311 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
130020311 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sfum01001
]
130020311 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
sfum01009
]
130020311 (PTK2)
Enzymes [BR:
sfum01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
130020311 (PTK2)
Protein kinases [BR:
sfum01001
]
Non-receptor tyrosine kinases
FAK family
130020311 (PTK2)
Protein phosphatases and associated proteins [BR:
sfum01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
130020311 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
FERM_F2
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
130020311
NCBI-ProteinID:
XP_055966885
LinkDB
All DBs
Position
Unknown
AA seq
1087 aa
AA seq
DB search
MAAAYLDPNLNHTPSSGTKAPLSTGAERSPGAMERLLKVFHYFESNSEPTTWASIIRHGD
ATDVRGIIQKIVDSHKVKHVACYGFRLSHLHSEEVHWLHLDMGVSSVREKYELAHPPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMSEVADQVDQEIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQ
TIQYSHSEDKDRKGTLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVSGASQSFIV
RPQKEGERALPSIPKLANSEKQGVRPHAVSVSGITHCQHRAKRARRFFPLVFCSHEPPSA
DEISGDETDDYAEIIDEEETYTMPSTRDYEIQRERIELGRCIGEGQFGDVHQGVYMSPEN
PALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGE
LRSFLQVRKHSLALASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFG
LSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGV
KNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSAILEEEKVQ
QEERLRMESRRQVTVSWDSAGPDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQANHYQVSA
YPGPHGVTATAGSIYPGQASLLDQTDTWNHRAQEVSMWRPTVEDSAALDLRGIGQVLPAH
LMEERLIRQQQEMEEDQRWLEKEERSLQKPDVRLSRGSMDREDGGLQGSTGNQHIYQPVG
KPDPAAPPKKPPRPGAPGHLGSLASLSSPGDSYNEGIKLQPQEISPPPTANLDRSSDKVY
ENVTGLVKAVIEMSSRIQPAPPEEYVPMVKEVGLALRTLLATVDETIPALPASTHREIEM
AQKLLNSDLGELINKMKLAQQYVLTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLKM
LGQSRPR
NT seq
3264 nt
NT seq
+upstream
nt +downstream
nt
atggcagccgcttacctcgacccgaacctgaaccacacacccagctccggcaccaaggcc
ccgctgagcacaggcgcggaacgctcccctggggccatggagcggctcttgaaggtcttc
cattatttcgagagcaatagtgagccgaccacgtgggccagtattatcaggcatggagac
gccacagatgtcaggggcatcatccagaagatagtggatagtcacaaggtcaagcacgtg
gcctgctacggattccgcctgagtcacctgcactcggaggaggttcactggctgcatctg
gatatgggcgtctccagcgtgcgggagaagtacgagctggcacacccgcctgaggagtgg
aagtatgaattgagaattcgttatttgccaaaaggatttctaaaccagtttactgaagac
aagccaactctgaatttcttctatcaacaggtgaagagcgactacatgtcagaggttgcc
gaccaagtggaccaggaaatcgccctgaagctgggttgcctcgagattcggcgatcctac
tgggagatgcggggcaacgcgctggagaagaagtccaactacgaggtgttagagaaagat
gttgggttgaagcggtttttccctcggagcttactggattctgtcaaggccaaaacacta
aggaagctcatccagcagacgtttcgacagtttgccaacctgaaccgggaagaaagtatc
ctcaagttctttgagatcctctccccggtgtacagattcgacaaggaatgcttcaagtgt
gccctggggtcaagctggattatttcggtggaactggccattggtcctgaagaaggcatc
agttacctcacggacaagggctgcaaccccacgcacctggctgacttcaaccaagtgcag
accattcagtattcgcacagcgaggacaaggaccgcaaagggacgctgcagctgaagata
gcaggcgcccctgagcccctcacagtgactgcaccgtccctcaccatcgcagagaacatg
gccgacctgatcgacggctactgccggctggtgagcggggcctcgcagtctttcatcgtc
cggcctcagaaagaaggtgaacgggctttgccatccataccaaagttggccaacagcgag
aagcagggtgtgcggccacacgccgtctccgtgtcaggaatcactcactgccagcacaga
gctaagagggctaggcgcttcttccccctggtcttctgctcccacgagcctccttccgcc
gatgaaattagtggggacgaaacggacgattatgccgagatcatagacgaagaggagacg
tacaccatgccctcaaccagggattatgagattcagagagaaagaatagaacttggacgg
tgtattggagaaggccagtttggagatgtccaccaaggcgtttacatgagtccagagaac
ccagcactggctgtcgctataaagacatgtaaaaactgtacttcggacagcgtcagagag
aagttcctgcaggaagccttgaccatgcggcagttcgaccaccctcacattgtgaagctg
attggcgttatcactgagaaccccgtgtggatcatcatggagctgtgcacgcttggagag
ctgaggtcattcctgcaagtgaggaagcacagcctggccctggcctctctgatcctgtat
gcctaccagctgagcacagctctcgcctacctggagagcaagagattcgtgcacagggac
attgctgctcggaatgttctggtgtcctccaatgactgtgtgaaattaggagactttggc
ttgtcccgctacatggaagacagcacgtactacaaagcttccaaggggaaactgcctatt
aaatggatggctcccgagtccatcaacttccggcgcttcacctcggccagtgacgtgtgg
atgtttggtgtgtgtatgtgggagattctcatgcatggtgtgaagccttttcaaggagtg
aagaacaatgatgtgatcgggcggattgagaatggggaaagattaccaatgcctccaaat
tgccctcccaccctctacagccttatgacgaagtgctgggcctatgaccccagcaggcgg
ccccggttcactgagctcaaagctcagctcagtgccatcctggaggaggagaaggtgcag
caggaggagcggctgaggatggagtcccggcggcaagtgacggtgtcctgggactcagca
ggccccgatgaagcaccacccaagcccagcagacctggctaccccagtccccggtccagc
gagggcttttaccccagcccgcagcacatggtccaggccaatcactaccaggtctctgcc
taccccggcccccacggggtcacagccacagcgggcagcatctacccaggccaggcctca
ctcctggaccagacagacacctggaatcacagagctcaggaggtttccatgtggcggccc
accgtggaggactctgccgccctggacctgcgtgggatcgggcaggtgctgcccgcacac
ctcatggaggagcggctgatccggcagcagcaggagatggaggaggaccagcgctggctg
gagaaggaggagcgctccctgcagaaaccggatgtgaggctctcgagaggcagcatggac
agggaggacggcggtctgcagggctcgaccgggaaccagcacatctaccagcctgtcggg
aagccagatcctgcagctccaccaaagaaaccgccgcgccctggtgcccctggccacctg
ggcagcctcgccagcctcagcagccctggggacagctacaacgaaggcatcaagttgcag
ccccaggagatcagcccacctcccactgccaacctggaccggtccagcgacaaggtgtat
gagaacgtgaccgggctggtgaaagcggtcatcgagatgtccagcaggatccagcccgcg
ccgcctgaggagtatgtgcccatggtgaaggaggtgggcctggccctgcggacgctgttg
gcaacagtggatgagaccatccctgcactgcccgccagcactcaccgagagattgagatg
gcccagaaactgctgaactcggacctgggcgagctcatcaacaagatgaaactggcccag
cagtatgtcctgaccagcctccagcaggagtacaagaagcagatgctgaccgcggcccat
gccttggccgtggacgccaagaacttgctcgatgtcattgaccaggcgagactgaagatg
cttggacagtcgcggccacgctga
DBGET
integrated database retrieval system
