Sorex fumeus (smoky shrew): 130020969
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Entry
130020969 CDS
T10594
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4 isoform X1
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04010
MAPK signaling pathway
sfum04012
ErbB signaling pathway
sfum04020
Calcium signaling pathway
sfum04151
PI3K-Akt signaling pathway
sfum05014
Amyotrophic lateral sclerosis
sfum05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
130020969 (ERBB4)
04012 ErbB signaling pathway
130020969 (ERBB4)
04020 Calcium signaling pathway
130020969 (ERBB4)
04151 PI3K-Akt signaling pathway
130020969 (ERBB4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
130020969 (ERBB4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
130020969 (ERBB4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
sfum01001
]
130020969 (ERBB4)
Enzymes [BR:
sfum01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
130020969 (ERBB4)
Protein kinases [BR:
sfum01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
130020969 (ERBB4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
DUF3951
ABC1
Motif
Other DBs
NCBI-GeneID:
130020969
NCBI-ProteinID:
XP_055967643
LinkDB
All DBs
Position
Unknown
AA seq
1323 aa
AA seq
DB search
MKLATGLWVWGSLLVAARTVQPGASQSVCAGTENKLSSLSDLEQQYRALRKYYENCEVVM
GNLEITSIEHNRDLSFLRSIREVTGYVLVALNQFPYLPLENLRIIRGTKLYEDRYALAIF
LNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVST
NGSAGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSG
PKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVD
SSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCT
KINGNLIFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNL
VTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFST
INQRIVIRDNRKAENCTAEGMVCNRLCSSDGCWGPGPDQCLSCRRFSRGRTCIESCNLYD
GEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGT
NSFIFKYADQDRECHPCHPNCTQGCIGSSIEDCIGLMDRCSGPTSHDCIYYPWTGHSTLP
QHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAP
NQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEF
MDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCV
QIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIK
WMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPIC
TIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQ
NLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFV
YRDGGFATDQGVPLSYRATTSTIPEAPVVQGASAEIFDDSCCNGTLRKSVTPHVQEDSST
QRYSADPTVFAPERNPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDN
PEYHNASSGPSKAEDEYVNEPLYLNTFANTLGNAEYLKNNILSVPEKVKKAFDNPDYWNH
SLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPLVAENPEYLSEFSLKPGTVLPPPPYRHRN
TVV
NT seq
3972 nt
NT seq
+upstream
nt +downstream
nt
atgaagctggcgacaggactgtgggtctgggggagccttctggtggccgcgaggaccgtc
cagcccggcgcttctcaatcagtgtgtgctggaaccgagaataaactgagctctctctct
gacctggaacagcagtaccgagccttgcgcaagtactatgagaactgcgaggtagtcatg
ggcaacttggagataaccagcatcgaacacaaccgggacctctctttcctgcggtctatt
cgagaagtcacaggctacgtgttagtggctctcaatcagtttccttacctgcctctggaa
aatttacgcattattcgtggtacaaaactttatgaggatcgatatgccttggcaatattt
ttaaactacagaaaagatggaaattttggacttcaagaacttggattgaagaacttgaca
gaaatcctaaatggtggtgtttatgtagaccagaacaaattcctttgttatgcagataca
attcattggcaagatattgttcggaatccttggccttccaacttgaccctggtgtcgacc
aatggtagcgcaggatgtggtcgttgccataagtcctgtactggccgatgctggggaccc
acagaaaatcattgtcaaactttgacacggacagtgtgtgcagaacaatgtgatgggcgg
tgctacggaccctatgtgagtgactgctgccatcgagaatgtgctggaggttgctctgga
cccaaggatacagactgctttgcctgcatgaatttcaatgacagtggagcgtgtgttact
cagtgtccccaaacttttgtctacaatccaaccacttttcaattagaacataacttcaat
gcaaagtacacatacggagcattctgtgtcaagaagtgtccacataactttgtagtcgat
tccagttcttgtgtacgtgcctgccctagttccaagatggaagtagaagaaaatggaatt
aaaatgtgtaaaccttgcacagatatttgcccaaaagcttgtgatggcattgggacggga
tcactgatgtcagctcagactgtggattccagtaacattgacaaatttataaactgcacc
aaaatcaatgggaatttgatcttccttgtcacaggcattcatggggatccttataatgca
atagaggccatagacccagagaaattgaatgtctttcggacggttcgagagataacaggt
ttcttgaacatacaatcatggccaccaaacatgactgactttagtgttttttctaacctg
gtcactatcggaggaagagtactctatagtggcctctctttacttatcctcaagcaacaa
ggtattacttctctacagttccaatctctgaaggaaatcagcgcaggaaacatctatatc
actgacaatagcaacttgtgttattaccataccataaattggacaactcttttcagcacc
atcaaccaaagaatagtgatccgggacaataggaaagctgaaaactgtactgcggaagga
atggtgtgtaatcgtctgtgttccagtgatggctgttggggacctgggccagaccagtgc
ctgtcatgtcgccgtttcagcaggggacggacctgtatagagtcttgtaatctctatgac
ggtgaatttcgggagtttgagaatggttccatctgtgtggaatgtgacccccagtgtgag
aagatggaggatggtctcctcacctgccatggaccgggacctgacaactgtacaaagtgc
tctcactttaaagatggaccaaactgtgtggaaaaatgtccagatggcttgcagggtaca
aatagttttattttcaagtatgctgaccaggatcgggaatgccacccatgccatccaaat
tgtactcaggggtgcataggctcaagtattgaggactgcattggcctgatggataggtgt
agcggtcccactagtcatgactgcatttactacccttggacgggccattccactttacca
caacatgctagaactcctctcattgcagctggagttattggtggactctttattttggtc
atcgtgggcctaacatttgcagtttatgttagaaggaagagcatcaaaaagaaaagagca
ttgaggagattcctggaaacagagctggtggaacctttaactcccagcggcacagcaccc
aatcaagctcaacttcgaattttgaaagaaactgagctcaaaagggtaaaagttcttggc
tcaggtgcttttggaactgtttataagggcatctgggtacctgaaggagaaacagtgaaa
atccctgtggctattaagattcttaatgaaacaacgggtcccaaagccaatgtggaattc
atggatgaagcactgatcatggctagtatggaccatccgcacttagtccggttgttaggt
gtgtgtctgagcccaaccatacagctggttacacagctaatgccacacggttgcctattg
gattatgtccacgaacacaaggataacattggatcacaattgctgcttaattggtgtgtc
cagatagctaagggaatgatgtatttggaagaaagacgacttgttcatcgggatttggca
gcccgtaatgtcttagtgaaatctccaaaccatgtgaaaatcacggactttggactagca
agacttttggaaggagatgaaaaagagtataacgctgatgggggaaagatgccaattaaa
tggatggctctggagtgtatacattataggaaatttacccatcagagtgatgtttggagc
tacggagtcactatctgggaattgatgacctttggaggaaaaccgtatgatggaattcct
acccgagaaatccctgatttattggagaaaggagaacgtttgccccagcctccaatttgc
actattgacgtttacatggtcatggtcaaatgttggatgattgatgctgacagtagacct
aaattcaaggaactagccgctgaattttcaaggatggctagagaccctcaaagataccta
gttattcagggtgatgatcgtatgaaacttccgagtccaaatgatagcaagttttttcaa
aatcttttggatgaagaggacttagaagatatgatggatgctgaggaatacctggtccca
caggcttttaatatcccaccacccatctatacttccagagcaagaattgattcaaatagg
agtgaaattggacacagccctcctcctgcctacacccccatgtcaggaaaccagtttgta
taccgagatgggggctttgctacagaccaaggggtacctttgtcctaccgagctaccacc
agcacgattccagaagctccagttgttcagggtgcttccgctgaaatttttgatgactcc
tgctgtaacggaaccctccgcaagtcagtaacaccccatgtgcaagaggatagcagcacc
cagaggtacagtgctgaccccacagtgtttgctccggaaaggaacccacgaggagagctg
gatgaagaaggttacatgactcctatgcgagacaaacccaaacaagaatacctgaaccct
gtggaggaaaacccttttgtttctcggagaaagaacggagaccttcaggctttggataac
cctgaatatcacaatgcttcgagtggtccatccaaggcagaggatgagtatgtgaatgag
ccactgtacctcaacacctttgccaacaccctgggcaacgctgagtacctgaagaacaac
atactgtctgtgccagagaaggtcaagaaagcgtttgacaaccccgattactggaaccac
agtctgccgcctcggagcacccttcagcacccagactacctgcaggagtatagcacaaaa
tatttttataagcaaaatggacggatccgcccccttgtggccgagaatcctgaatacctc
tctgagttctccctgaagcccggcactgtgctgcctccccctccctacagacaccgaaac
actgtggtgtaa
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