Sorex fumeus (smoky shrew): 130021070 Help Entry 130021070         CDS       T10594                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum01524   Platinum drug resistance sfum04115   p53 signaling pathway sfum04210   Apoptosis sfum04215   Apoptosis - multiple species sfum04217   Necroptosis sfum04620   Toll-like receptor signaling pathway sfum04621   NOD-like receptor signaling pathway sfum04622   RIG-I-like receptor signaling pathway sfum04623   Cytosolic DNA-sensing pathway sfum04625   C-type lectin receptor signaling pathway sfum04657   IL-17 signaling pathway sfum04668   TNF signaling pathway sfum04932   Non-alcoholic fatty liver disease sfum04936   Alcoholic liver disease sfum05010   Alzheimer disease sfum05016   Huntington disease sfum05022   Pathways of neurodegeneration - multiple diseases sfum05132   Salmonella infection sfum05134   Legionellosis sfum05142   Chagas disease sfum05145   Toxoplasmosis sfum05152   Tuberculosis sfum05160   Hepatitis C sfum05161   Hepatitis B sfum05162   Measles sfum05163   Human cytomegalovirus infection sfum05164   Influenza A sfum05165   Human papillomavirus infection sfum05167   Kaposi sarcoma-associated herpesvirus infection sfum05168   Herpes simplex virus 1 infection sfum05169   Epstein-Barr virus infection sfum05170   Human immunodeficiency virus 1 infection sfum05200   Pathways in cancer sfum05203   Viral carcinogenesis sfum05416   Viral myocarditis sfum05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:sfum00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     130021070 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     130021070 (CASP8)    04215 Apoptosis - multiple species     130021070 (CASP8)    04217 Necroptosis     130021070 (CASP8)    04115 p53 signaling pathway     130021070 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     130021070 (CASP8)    04621 NOD-like receptor signaling pathway     130021070 (CASP8)    04622 RIG-I-like receptor signaling pathway     130021070 (CASP8)    04623 Cytosolic DNA-sensing pathway     130021070 (CASP8)    04625 C-type lectin receptor signaling pathway     130021070 (CASP8)    04657 IL-17 signaling pathway     130021070 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     130021070 (CASP8)    05203 Viral carcinogenesis     130021070 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     130021070 (CASP8)    05161 Hepatitis B     130021070 (CASP8)    05160 Hepatitis C     130021070 (CASP8)    05164 Influenza A     130021070 (CASP8)    05162 Measles     130021070 (CASP8)    05168 Herpes simplex virus 1 infection     130021070 (CASP8)    05163 Human cytomegalovirus infection     130021070 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     130021070 (CASP8)    05169 Epstein-Barr virus infection     130021070 (CASP8)    05165 Human papillomavirus infection     130021070 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     130021070 (CASP8)    05134 Legionellosis     130021070 (CASP8)    05152 Tuberculosis     130021070 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     130021070 (CASP8)    05142 Chagas disease     130021070 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     130021070 (CASP8)    05016 Huntington disease     130021070 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     130021070 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     130021070 (CASP8)    05416 Viral myocarditis     130021070 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     130021070 (CASP8)    04932 Non-alcoholic fatty liver disease     130021070 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     130021070 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:sfum01002]     130021070 (CASP8) Enzymes [BR:sfum01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      130021070 (CASP8) Peptidases and inhibitors [BR:sfum01002]  Cysteine peptidases   Family C14: caspase family    130021070 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED IBD PYRIN Beta-prop_WDR5 Motif Other DBs NCBI-GeneID:  130021070 NCBI-ProteinID:  XP_055967807 LinkDB All DBs Position Unknown AA seq 487 aa AA seqDB search MSFSNLLYSIGEELGSEDLASLKFLCSDHIPQRQQEPIKDALMLFLRLQEKRMLEEDDIF FLKELLFQIKRFDLLVKYLDTDPRDVEEELQISDKAQISAYRVMLFQISEELSKNEVKQF KFLLSELISKCKLDEDMNLFDIFIEMEKRDILGKNNLEYLKEIRHINKSVLKKISDYEKS TEEGKMSLTRTPDQLANVHVFVSQMLTVERSLELLTISDSSGQQGSQPQTSYPVYQMKSK PRGFCLIINNYDFSVARKNVRKLRQVKDRSGTDMDAAELNKSFSDLHFEVVTYRNCEAEK ICEILKEFQGKDHSEKDCFVCCILSHGDKGIIYGSDGQEVSIYTVTSFFTGKDCPSLRNK PKVFFIQACQGETYQKGVAIESDSNQRELCLDTDALNHKYIPDESDFLLGMATVYDCVSY RDPTKGTWYIQSLCRHLRDGCSRGDDILTILTKVNNEVSTMDDIKNNGKQMPQPTFTLRK KLMFPLN NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atgagtttcagcaaccttctctatagtattggggaagagttgggcagtgaagacctggcc tccctcaagttcctgtgcagtgaccatatcccacagaggcagcaggaacccatcaaggat gctttaatgttattcctgagacttcaggaaaagagaatgttggaggaagacgacatattc ttcttgaaggagctgcttttccaaattaagagatttgatcttttggttaaatacttggac accgacccaagagacgtggaggaggaactccagatatcggacaaggctcagatctctgcc tacagggttatgctttttcagatttcagaagaattaagcaaaaacgaagtgaagcagttt aagtttttgttgagtgagttgatttccaaatgtaaactggatgaagacatgaacttgttc gatattttcatagagatggaaaagagggacatccttgggaaaaacaacttggaatatttg aaggaaatccgtcacatcaacaagagtgtgctcaagaagatcagtgactatgaaaaatct actgaagaggggaagatgagtcttacaagaaccccagatcagttggccaatgtacatgtt tttgtgtctcaaatgctcacagttgaaaggtcgctggaattgctgacaatatccgattct tcaggacagcagggcagtcagccacagacatcataccctgtttaccaaatgaagagcaaa cctcggggattttgtttgatcattaacaattacgattttagtgtggcaagaaaaaatgta cgcaaacttcgccaggtgaaggacagaagtggtacagatatggatgcagcggaattgaac aagagcttcagtgatcttcattttgaggtagtgacttacagaaactgcgaagcagagaaa atctgtgagattttgaaggaattccaaggcaaggaccatagtgaaaaggactgtttcgtc tgctgcatcctctctcatggagataaaggcattatctatggctctgatgggcaggaagtc tctatctacacagtgacctctttcttcactggtaaagactgtccttcccttcgaaacaaa cccaaagtcttttttattcaggcttgtcaaggagagacataccaaaaaggggtagctatt gaaagtgactcaaatcagcgggagctgtgcttagacacggacgcattgaaccacaagtat atcccagatgaatctgactttctgctggggatggccactgtgtacgactgcgtttcctat cgagaccccacaaaggggacatggtacatccagtcgctttgccggcaccttagagacgga tgttctaggggtgacgatattcttaccatcctcactaaagtgaacaatgaagtgagcact atggatgatataaaaaataatgggaaacagatgccacaacctacattcacactgagaaaa aaactcatgttccctctgaattga

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