Sorex fumeus (smoky shrew): 130022114 Help Entry 130022114         CDS       T10594                                  Symbol SHC2 Name (RefSeq) SHC-transforming protein 2   KO K17447   SHC-transforming protein 2 Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum01521   EGFR tyrosine kinase inhibitor resistance sfum01522   Endocrine resistance sfum04012   ErbB signaling pathway sfum04014   Ras signaling pathway sfum04062   Chemokine signaling pathway sfum04072   Phospholipase D signaling pathway sfum04370   VEGF signaling pathway sfum04510   Focal adhesion sfum04650   Natural killer cell mediated cytotoxicity sfum04722   Neurotrophin signaling pathway sfum04910   Insulin signaling pathway sfum04915   Estrogen signaling pathway sfum04917   Prolactin signaling pathway sfum04926   Relaxin signaling pathway sfum04935   Growth hormone synthesis, secretion and action sfum05034   Alcoholism sfum05100   Bacterial invasion of epithelial cells sfum05214   Glioma sfum05220   Chronic myeloid leukemia sfum05224   Breast cancer sfum05225   Hepatocellular carcinoma sfum05226   Gastric cancer Brite KEGG Orthology (KO) [BR:sfum00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     130022114 (SHC2)    04014 Ras signaling pathway     130022114 (SHC2)    04370 VEGF signaling pathway     130022114 (SHC2)    04072 Phospholipase D signaling pathway     130022114 (SHC2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     130022114 (SHC2)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     130022114 (SHC2)    04062 Chemokine signaling pathway     130022114 (SHC2)   09152 Endocrine system    04910 Insulin signaling pathway     130022114 (SHC2)    04915 Estrogen signaling pathway     130022114 (SHC2)    04917 Prolactin signaling pathway     130022114 (SHC2)    04926 Relaxin signaling pathway     130022114 (SHC2)    04935 Growth hormone synthesis, secretion and action     130022114 (SHC2)   09156 Nervous system    04722 Neurotrophin signaling pathway     130022114 (SHC2)  09160 Human Diseases   09162 Cancer: specific types    05225 Hepatocellular carcinoma     130022114 (SHC2)    05226 Gastric cancer     130022114 (SHC2)    05214 Glioma     130022114 (SHC2)    05220 Chronic myeloid leukemia     130022114 (SHC2)    05224 Breast cancer     130022114 (SHC2)   09171 Infectious disease: bacterial    05100 Bacterial invasion of epithelial cells     130022114 (SHC2)   09165 Substance dependence    05034 Alcoholism     130022114 (SHC2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     130022114 (SHC2)    01522 Endocrine resistance     130022114 (SHC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PID SH2 DUF7063 DUF7145 Motif Other DBs NCBI-GeneID:  130022114 NCBI-ProteinID:  XP_055968833 LinkDB All DBs Position Unknown AA seq 584 aa AA seqDB search MTQGPGGRAPPAPPAPPEPEAPTTFCALLPRMPQWKFAAPAGFLGRGPGARAAGGAGGAG GADPQPEPPGPASVPALAAAVLGACEPRCAAAPCPLPALSRCRAAGTRGPRGARGAAPDA AADEWIRKGSFIHKPAHGWLHPDARVLAPGVSYIVRYMGCIEVLRSMRSLDFNTRTQVTR EAINRLHEAVPGVRGSWKKKAPNKALASILGKSNLRFAGMSIAVSISVDGLNLSVPATRQ IIANHHMQSISFASGGDTDMTDYVAYVAKDPINQRACHILECCDGLAQSVISTVGQAFEL RFKQYLHSPPTVVVPPERLTGPEESAWGDEEENEHNYYNSIPGKEPPPGGLVDSRLTLTQ PSALGALGQGTSPARRDTRGLQWDLGPSAPPGDGYVQADARGPQDYEDHLYVNTQGLDGL ELLRPEDSPQKDLFDMRPFEDALKLHECSLVAVSAAPVATVPVEDQWPSPPTRRAPIAPT EEQLRQEPWYHGQMSRRAAEKLLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPE GVVRTKDVLFESISHLIDYHVQNGQPIVAAESELHLRGVVKREP NT seq 1755 nt NT seq  +upstreamnt  +downstreamnt atgacgcagggtccgggcgggcgcgcgccccccgcgccccccgcgcccccggagcccgag gcgcccaccacgttctgcgcgctgctgccccgcatgccgcagtggaaattcgccgccccg gccggcttcctggggcgcggtcccggggcgcgggcggcggggggcgcgggcggcgcgggg ggcgcggacccccagcccgagccgcccggccccgccagcgtccccgcgctggccgccgcg gtgctgggcgcctgcgagccccgctgcgccgccgcgccctgccccctgccggcgctcagc cgctgccgcgccgcgggaacccgggggccgcggggggcgcggggggcggccccggacgcc gccgccgacgagtggatccgcaaaggcagcttcatccacaagcccgcgcacggctggctg caccccgacgcccgggtcctggcgccgggggtctcctacatcgtgcggtacatgggctgc atcgaggtgctccgttctatgcgctccctggatttcaacacccgcacccaggtcaccagg gaagcaatcaaccggctccatgaggccgtgcccggtgtgcggggctcctggaagaagaag gcccccaacaaggccctggcctccattctgggcaagagcaacttgcgtttcgccggcatg agcatcgccgtcagcatctccgtggatggactcaacctttccgtgcctgccacccgccag attatcgccaaccatcatatgcagtctatttccttcgcatcgggcggcgacacggacatg acagattacgtggcctatgtcgctaaggaccccatcaaccagagagcctgtcacatcctg gagtgctgtgatggcttggcgcagagtgtcatcagcaccgtgggccaggccttcgagctg cgtttcaaacagtacctgcacagccccccgactgtggtcgtgccccccgagaggctgacg ggccccgaggagtcggcctggggggacgaggaggagaacgaacataactactacaacagc atcccggggaaggagccgcccccgggtgggctggtggactccaggctcaccctcacacag cccagcgccctcggggccctcggccagggaacctccccagctcgaagagacacccggggc ctgcaatgggatctgggcccctcagccccgccaggggacggctatgtgcaggcggacgcc cgaggtccccaagattatgaggatcacctctatgtcaacacacagggtctggatggcctg gagctcctgcgtcctgaggacagtccccagaaggacctatttgacatgcgaccctttgag gacgccctgaagctgcacgagtgctccctggtggcggtctcggcagcccctgtggccacg gtccccgtggaggaccagtggcccagccctcccacccgccgggcccccatcgcccccacg gaggaacagctgcggcaggagccctggtaccacggccagatgagccgtcgggctgcagag aaactgctgcgcgctgatggggacttccttgtacgtgacagcgtcacgaacccagggcag tacgtgctcactggcatgcacgctgggcagcccaagcacctgctgctcgtggacccggaa ggcgtggtgcggaccaaggacgtgctgttcgagagcatcagccacctgatcgactaccac gtgcagaacgggcagcccatcgtggccgccgagagcgagctgcacctgcgcggcgtggtc aagcgggagccctga

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