KEGG   Sorex fumeus (smoky shrew): 130024876
Entry
130024876         CDS       T10594                                 
Symbol
SQSTM1
Name
(RefSeq) sequestosome-1 isoform X1
  KO
K14381  sequestosome 1
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum04137  Mitophagy - animal
sfum04140  Autophagy - animal
sfum04217  Necroptosis
sfum04218  Cellular senescence
sfum04380  Osteoclast differentiation
sfum05014  Amyotrophic lateral sclerosis
sfum05022  Pathways of neurodegeneration - multiple diseases
sfum05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    130024876 (SQSTM1)
   04137 Mitophagy - animal
    130024876 (SQSTM1)
  09143 Cell growth and death
   04217 Necroptosis
    130024876 (SQSTM1)
   04218 Cellular senescence
    130024876 (SQSTM1)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    130024876 (SQSTM1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    130024876 (SQSTM1)
   05022 Pathways of neurodegeneration - multiple diseases
    130024876 (SQSTM1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    130024876 (SQSTM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sfum04131]
    130024876 (SQSTM1)
   03029 Mitochondrial biogenesis [BR:sfum03029]
    130024876 (SQSTM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sfum04147]
    130024876 (SQSTM1)
Membrane trafficking [BR:sfum04131]
 Autophagy
  Mitophagy
   Cargo receptors
    130024876 (SQSTM1)
  Pexophagy
    130024876 (SQSTM1)
  Aggrephagy
    130024876 (SQSTM1)
  Xenophagy
    130024876 (SQSTM1)
  ER-phagy
   ER-phagy recepters
    130024876 (SQSTM1)
  Other autophagy associated proteins
   Midbophagy
    130024876 (SQSTM1)
Mitochondrial biogenesis [BR:sfum03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    130024876 (SQSTM1)
Exosome [BR:sfum04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   130024876 (SQSTM1)
SSDB
Motif
Pfam: UBA_5 ZZ PB1
Other DBs
NCBI-GeneID: 130024876
NCBI-ProteinID: XP_055971671
LinkDB
Position
Unknown
AA seq 405 aa
MAAFTVKAYLLGKEDATREIRRFSFSVAPEAEAEAGGGRACERLLARVAALFPALRPGGF
QAHYRDEDGDLVAFSSDEELNMALAYVKDDLFRVYIKERKECRREHRAACAQDGAPRPLV
HPNVICDGCNGPVVGTRYKCSVCPDYDLCAACEGKGLHREHAKLAFPGLLGHLSEGFSHS
RWLRKLKHGHFGWPGCEMAPPGNWSPRPPRAGDARASPTAAPSDAAGAGPSEDPSVNFLK
NVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSAGSSGSEDKAGPPSCSGSPSPNQPSV
DATGGAALSLAEQMKKIVLESGLQTEGQMESDTCSGGDDDWTHLSSKEVDPSTEADPRLI
ESLSQMLSMGFSDEGGWLTRLLQTKNGDIGAALDAIQYSKHPPPL
NT seq 1218 nt   +upstreamnt  +downstreamnt
atggcggcgttcacggtcaaggcctacctgctgggcaaggaggacgccacccgcgagatc
cgccgcttcagcttcagcgtcgcgcccgaggccgaggcggaggctgggggcggccgggcc
tgcgagcggctgctggcgcgggtggccgcgctgttccccgcgctgcggccggggggcttc
caggcgcactaccgcgatgaggacggggacttggtggccttctccagcgacgaggagctg
aacatggccctggcctacgtgaaggacgacctcttccgcgtctacatcaaagagaggaag
gagtgccggcgggagcaccgtgccgcctgcgcgcaggacggggcgccccgccccctggtg
caccccaacgtcatctgcgatggctgcaacgggccggtagtgggcacccggtacaagtgc
agcgtctgccctgactacgacctgtgcgccgcctgcgagggcaagggcctgcaccgcgag
cacgccaagctggccttcccggggctgctgggccatctctccgagggcttctcgcacagc
cgctggctccgcaaactgaagcacggccacttcgggtggcctggctgcgagatggcgccc
cctgggaactggagcccgcgcccgcccagggccggggacgcccgggccagccccaccgcg
gcaccttcggatgcagccggcgccgggccctcggaggaccccagtgtgaacttcctgaag
aacgtgggggagagcgtggctgccgccctcagtcctctgggcatcgaagtagacattgac
gtggagcacggtgggaagaggagccgcctgacaccagtgtccgcgggcagctctggctcc
gaggacaaggcgggccccccgtcctgcagcggctcccccagtcccaaccagcccagcgtg
gatgccacggggggcgccgcgctgtccctggcggagcagatgaagaagatcgtcctggag
tcgggactgcagactgagggacagatggagtcggacacctgctcgggaggcgacgatgac
tggacacacctgtcctccaaggaggtggacccgtccacagaagccgacccgcggctgatc
gagtcgctgtcacagatgttgtccatgggcttctcggacgagggcggctggctgacccgc
ctcctgcagaccaagaacggtgacatcggggcggcgctggatgccatccagtactccaag
cacccaccgcccctgtga

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