Sorex fumeus (smoky shrew): 130025976 Help Entry 130025976         CDS       T10594                                  Symbol EGF Name (RefSeq) pro-epidermal growth factor   KO K04357   epidermal growth factor Organism sfum  Sorex fumeus (smoky shrew) Pathway sfum01521   EGFR tyrosine kinase inhibitor resistance sfum04010   MAPK signaling pathway sfum04012   ErbB signaling pathway sfum04014   Ras signaling pathway sfum04015   Rap1 signaling pathway sfum04020   Calcium signaling pathway sfum04066   HIF-1 signaling pathway sfum04068   FoxO signaling pathway sfum04072   Phospholipase D signaling pathway sfum04151   PI3K-Akt signaling pathway sfum04510   Focal adhesion sfum04540   Gap junction sfum04630   JAK-STAT signaling pathway sfum04810   Regulation of actin cytoskeleton sfum05160   Hepatitis C sfum05165   Human papillomavirus infection sfum05200   Pathways in cancer sfum05207   Chemical carcinogenesis - receptor activation sfum05208   Chemical carcinogenesis - reactive oxygen species sfum05210   Colorectal cancer sfum05212   Pancreatic cancer sfum05213   Endometrial cancer sfum05214   Glioma sfum05215   Prostate cancer sfum05218   Melanoma sfum05219   Bladder cancer sfum05223   Non-small cell lung cancer sfum05224   Breast cancer sfum05226   Gastric cancer sfum05231   Choline metabolism in cancer sfum05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:sfum00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     130025976 (EGF)    04012 ErbB signaling pathway     130025976 (EGF)    04014 Ras signaling pathway     130025976 (EGF)    04015 Rap1 signaling pathway     130025976 (EGF)    04630 JAK-STAT signaling pathway     130025976 (EGF)    04066 HIF-1 signaling pathway     130025976 (EGF)    04068 FoxO signaling pathway     130025976 (EGF)    04020 Calcium signaling pathway     130025976 (EGF)    04072 Phospholipase D signaling pathway     130025976 (EGF)    04151 PI3K-Akt signaling pathway     130025976 (EGF)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     130025976 (EGF)    04540 Gap junction     130025976 (EGF)   09142 Cell motility    04810 Regulation of actin cytoskeleton     130025976 (EGF)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     130025976 (EGF)    05207 Chemical carcinogenesis - receptor activation     130025976 (EGF)    05208 Chemical carcinogenesis - reactive oxygen species     130025976 (EGF)    05231 Choline metabolism in cancer     130025976 (EGF)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     130025976 (EGF)   09162 Cancer: specific types    05210 Colorectal cancer     130025976 (EGF)    05212 Pancreatic cancer     130025976 (EGF)    05226 Gastric cancer     130025976 (EGF)    05214 Glioma     130025976 (EGF)    05218 Melanoma     130025976 (EGF)    05219 Bladder cancer     130025976 (EGF)    05215 Prostate cancer     130025976 (EGF)    05213 Endometrial cancer     130025976 (EGF)    05224 Breast cancer     130025976 (EGF)    05223 Non-small cell lung cancer     130025976 (EGF)   09172 Infectious disease: viral    05160 Hepatitis C     130025976 (EGF)    05165 Human papillomavirus infection     130025976 (EGF)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     130025976 (EGF)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:sfum04052]     130025976 (EGF) Cytokines and neuropeptides [BR:sfum04052]  Cytokines   Growth factors (RTK binding)    130025976 (EGF) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ldl_recept_b cEGF FXa_inhibition EGF_CA EGF EGF_3 Vgb_lyase Plasmod_Pvs28 Motif Other DBs NCBI-GeneID:  130025976 NCBI-ProteinID:  XP_055972618 LinkDB All DBs Position Unknown AA seq 1110 aa AA seqDB search MVWLSLILWLAASQFCSVHPSALAAWNCPSSSAPGSGNSRVGPVPFLIFSHGNSIYRIDP EGTNYEKLVPDAGVSPILDFHYKEERLYWVNLERQLLQRAFLNGTGQETLCAVQEYVSGM AINWINEEIIWSNQQKGIITVTDMKGNNSRVLLRSLKYPANIAVDPIERFLFWSAEKVGS IHRADLRGMGVKTLIQGAGKIAAMSLDVAEKRLFWSQELRGGDGAHVCSCSYDGRSTQCN KQLLRNALFSMSPFGDRIFYSTRDKKTVCIASKHTGKEMVHISLPLPLLPLKRIKVVHPG VQPMAEGATWGSAQRHCKLKRGRGGECTYGQEPAPPLCPCAQGFRLSQDGKSCEDVNECA LQNHGCTLGCENTPGSYYCTCPEGFVLLPDGKQCQSFVSCPCSDLGCSHNCVLTSQGPTC FCPEGSVLQADGRTCSGCSSPDNGGCSHLCLPHGPGSWRCGCFPGYDLHQDGKRCVASGP PPFLLFANSQDIRYMRFDGTAYSRVLAQQKGTIWALDYDPVENKIYFAHSTLGGIERANL DGSWRERLIEGDMGVPEGLAVDWLGRKLYWTDREKSRIERSDLNGSQRETILKTGVTQPL GIAVHPLAKRLFWTDTGTQPQIKSSSLQGTDPLVVASSGLVRPSGIVIDYLADTLYWCDT ERAVIEMANLDGSNRRTLVQNDVGRPFAMAVFEDVLWVSDWARPSLSRMDKRTGGQRVWL RAGMQKPSALAVVHPLAKPGANPCVQSKSHCEQLCREGFGAAQYLCPEGLERTPDGNDTN LGPSVMPSDAPPSGSLEADVTVTGSQPLPVVEITLSGQGDCGPQGCGPNAQCKFLGENAT CRCLEGFTEDGKLCVDLDECQRGTHTCGENATCANTEGSYRCLHAPGQSCPGVTPPSHAG KEGQLAVRTFHEDCPPLYDGYCLHGGQCMYFKILESVACRCLVGYTGPRCEFLNLVDLRS VRPWQPGSGTVAAACLGALVLLLLALLGLLHCHRARRRHLNAPKDPTAASGSGKAPVGVP PGPQPWFVVLKEHQDGSSQGHPDPLKDRADADGPRAHAGQLSRPEPGPVPLTVCRMPLPT QAESTEPGVRLAPSLQPDPGSAPQAPAKDS NT seq 3333 nt NT seq  +upstreamnt  +downstreamnt atggtgtggctctcactcattctgtggttggcggcttcgcaattctgttcggttcatccc tcggcactggccgcatggaactgtcccagcagctcagccccgggaagtgggaactcccgc gtgggtcctgtccccttcttaattttctcccacggaaatagtatctacagaattgaccca gaaggaaccaattatgaaaaactggtgcctgatgctggtgtttcacccatcctggatttt cactacaaggaggaaagactctattgggtcaatttagaacgtcagctgttgcaaagggct ttcctgaacggcactgggcaagagacactatgtgctgtacaggaatatgtctcaggaatg gcaataaattggataaatgaagaaattatttggtcaaatcaacagaaaggaatcatcaca gtgacagatatgaagggaaacaattctcgagtcctcttacgctctttaaaataccctgca aatatagcagttgatccaatagaaaggttcctgttttggtctgcggagaaggtgggcagc attcaccgggcagatctccgtggcatgggagtgaagacgctgatccaaggggcagggaaa atagctgccatgtctctggatgtggctgagaagcggctcttctggagccaggagctgagg ggaggagacggcgctcacgtttgttcctgcagttatgatggacgttccacacagtgcaac aaacaactcctgcggaatgctttgttctctatgtcgccttttggtgatcgcatcttctat tcaacgagggacaagaagacagtttgcatcgctagcaagcacacggggaaggagatggtt catattagccttccgctgccacttctgccacttaaaagaataaaagtggtgcacccgggt gtccagcccatggcagagggtgccacatggggatccgctcagaggcactgcaagctgaag agaggcagaggtggagaatgcacctatggtcaggagcccgcaccccctctgtgcccatgt gctcagggcttcaggctcagccaagatggaaagtcctgtgaagatgtcaacgagtgtgcc ctccagaaccatggctgcacgctgggctgcgagaacacgcccgggtcctactactgcacg tgtcctgaggggttcgtgctgctgcccgacgggaaacagtgtcagagctttgtgtcctgc ccctgcagcgacctgggctgcagccacaactgtgtcctcacatcccaaggccccacgtgc ttctgtcccgagggctctgtgctccaggcagacggaagaacttgttctggctgctcgtca cctgacaatggcgggtgcagccacctctgcctcccacacggccctggctcctggcgatgc ggctgctttcccggctacgacctccaccaggatggaaagcgctgcgtggcctcaggcccg ccaccgtttttgctgtttgccaattctcaagacattcgctacatgcgttttgatggaact gcctacagccgcgtgcttgctcagcagaagggcaccatctgggccctggactacgacccg gtggaaaacaagatatacttcgcccacagcaccctgggcgggattgaaagggccaacctg gacgggtcctggcgagagaggctcatcgagggagacatgggggtgcccgagggcctcgca gtggactggctgggccggaagctctactggacagacagagagaaatcccgcatcgaacgg agcgatttaaatgggagccagcgcgagaccatcctgaagacaggtgtcacccaacccctg ggaatcgctgtgcacccgttggccaagcgattattctggaccgacacagggactcagccc caaattaaaagttcttccctccaaggcacagacccactggtggtcgccagctccggtctg gtccggcccagcggcatagtcattgactacttagcggacacactgtactggtgtgacacg gagcgtgctgtgatcgaaatggccaatctggatggttccaatcgccgaacacttgtccag aacgatgtaggacgcccgtttgccatggccgtgttcgaggacgttctgtgggtgtcagac tgggcgcgaccctcactcagcaggatggacaagaggacgggaggccagcgggtgtggctg cgggccggcatgcagaaaccctcggccctggccgtggtgcacccactggcaaagccagga gccaacccctgtgtccagtccaagagccactgtgagcagctttgcagagaggggtttgga gctgcccagtacttgtgccccgaaggtttggagagaaccccagatggtaatgacacaaat ttaggtccctcagtgatgccctcagatgccccacccagcggaagccttgaagctgacgtg acggtgacggggtctcagcctttgcccgtggtggaaatcaccctgtcagggcagggggac tgcggcccccagggatgcgggcccaacgcgcagtgcaagttcctgggagagaatgccaca tgccggtgtctggagggatttactgaggatggcaaactctgcgtggatcttgacgagtgc cagcggggcacacacacctgtggggagaacgccacctgcgccaacacggaagggagctac cgctgcctgcacgcacccggccagagctgtcccggcgtgaccccaccatcccatgccggg aaggaaggccagcttgcggtgcggacatttcatgaggactgcccgcccctgtacgacggc tactgcctgcatgggggccagtgcatgtacttcaagatacttgagagcgtcgcgtgcagg tgcctcgtgggctacaccgggccaaggtgcgagttcctgaacctggtggacctgcgcagc gtccggccttggcagccggggagcggcacagtggccgccgcctgcctgggggcgctggtc ctgctgctgctggcactgctggggctgctgcactgccacagggctcggaggcgacacttg aacgcgcctaaggaccccaccgcagcatctggaagcggaaaagcccctgtgggggtgccc cccggtccccagccctggtttgtggttctgaaggaacaccaggacggaagcagccagggc cacccagaccccctcaaggacagggcagatgctgatggccccagggcacacgctggccag ctctcccggcctgagccagggcctgtaccactgaccgtgtgcaggatgccgctgccgaca caagcagagagcacagagcctggagttcgcctcgcaccctctctgcagccggaccccggc tccgctccccaggcccccgcaaaggactcctaa

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