| Entry |
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| Symbol |
CACNA2D1
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| Name |
(RefSeq) voltage-dependent calcium channel subunit alpha-2/delta-1
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| KO |
| K04858 | voltage-dependent calcium channel alpha-2/delta-1 |
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| Organism |
sfum Sorex fumeus (smoky shrew)
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| Pathway |
| sfum04261 | Adrenergic signaling in cardiomyocytes |
| sfum05412 | Arrhythmogenic right ventricular cardiomyopathy |
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| Brite |
KEGG Orthology (KO) [BR:sfum00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
130027729 (CACNA2D1)
09150 Organismal Systems
09152 Endocrine system
04921 Oxytocin signaling pathway
130027729 (CACNA2D1)
09153 Circulatory system
04260 Cardiac muscle contraction
130027729 (CACNA2D1)
04261 Adrenergic signaling in cardiomyocytes
130027729 (CACNA2D1)
09160 Human Diseases
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
130027729 (CACNA2D1)
05412 Arrhythmogenic right ventricular cardiomyopathy
130027729 (CACNA2D1)
05414 Dilated cardiomyopathy
130027729 (CACNA2D1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:sfum04040]
130027729 (CACNA2D1)
Ion channels [BR:sfum04040]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
130027729 (CACNA2D1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
1082 aa
MAAGCLLAWTLTLFQFLLLGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVGQLADI
YEKYQDMYTVEPNNARQLVEKAATNIEQLLKSRSTALVRLAQEAEKVQAAHQWREDFASN
EVVYYNAKDDLDSEKNESEPGSQRIKPVFFEDANFGRQISYQHAAVHIPTDIYEGSTIVL
NELNWTSALDEVFKRNQREDPTLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR
RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD
VSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIML
FTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIR
INTQEYLDVLGRPMVLAGEKAKQVQWTNVYLDALELGLVITGTLPVFNITGQVENKTKNQ
LILGVMGIDVSLDDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKNPKSQEPVTLDF
LDAELENDIKVEIRNKMIDGESGDKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLAL
VLPTYSFYYIKAKIEDTITQARYSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLL
NFNEFIDRKTPNDPSCNTDLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGIT
RVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPNFNKTGPSAYESGIMVSKAVEIN
IQGKLLKPAVVGIKIDINSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLM
ANHDEYTNQIGRFFGEIDPSLMRHLINISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYV
PSIADILHIGWWATAAAWSILQQFLLSLSFPRLLEAADMEEEDFTASLSKQSCITEQTQY
FFDNDSKSFSGVLDCGNCSRIFHVEKLMNTNLVFIMVESKGTCPCDTRLLIQAEQTSDGP
DPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWSIIGIQFLLLWLLSGSRHY
QL |
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| NT seq |
3249 nt +upstreamnt +downstreamnt
atggctgctggctgcctgctggcctggactctgacacttttccaatttttgctgctcggt
ccctcgtcggaggagccgttcccttcggctgtcacaataaagtcatgggtggataagatg
caagaggaccttgtcactttggcaaaaacagcaagtggagtcggtcaacttgctgatatt
tatgagaaatatcaagatatgtatacagtggagccaaataatgcacgccagctggtggaa
aaggcagccacaaatattgagcaacttctgaaaagtagatctacagctctggtgcgtctg
gcccaggaagcagaaaaagttcaagcagcccaccagtggagagaggattttgcaagcaat
gaagttgtctactacaacgcaaaggatgatcttgattctgaaaagaatgaaagtgaacca
ggaagccagaggataaagcctgttttcttcgaagatgcgaactttggtcggcaaatatcc
tatcagcatgctgcagtccatattcccactgacatctatgagggctcgacaatcgtgtta
aatgaactgaactggacaagtgccttagatgaagtcttcaaaagaaatcaacgggaggat
cccacattgctgtggcaagtgttcggcagtgccacgggcctcgcccgatattatccagct
tctccatgggttgataacagcagaactccaaacaagattgatctttatgatgttcgcaga
agaccatggtacatccaaggagctgcatctcctaaggacatgctcattctggttgatgta
agtgggagtgttagtggattgacccttaaattgatccgcacatctgtctctgaaatgttg
gaaacactctcagatgatgattttgtgaatgtagcttcatttaacagcaatgcccaggat
gtaagctgttttcagcatcttgtccaagcaaatgtaagaaataagaaagtgctgaaagat
gcagtgaataatatcacagcaaagggaatcacagactataagaagggttttagttttgct
tttgaacagctgctcaattacaatgtttccagagccaactgcaataagattatcatgttg
ttcacggatggaggagaggagagagcccaggagatatttgccaaatataataaagacaaa
aaagtacgggtatttacattttcagttggtcaacataattatgacagagggcctattcag
tggatggcatgtgaaaataaaggttattattatgaaattccttccattggagcaataaga
atcaatactcaggaatatttggatgttctgggaagaccaatggttttagcaggagaaaaa
gctaagcaagtacaatggacaaatgtatatttggatgcattggaattgggacttgtcatt
actggaactcttcctgtcttcaatattactggccaagttgaaaataagacaaagaaccag
ctaatacttggtgtgatgggaattgatgtgtcattggacgatattaaaagactgacacca
cgttttacactgtgccccaatggctattattttgcaatagatcctaatggttatgtttta
ttacatccaaatcttcagccaaagaatcctaaatctcaggagccagtaacattggatttc
cttgatgcagaattagagaatgatattaaggtggagattcgtaataaaatgatagatggg
gaaagtggagataaaacattcagaactctggttaaatctcaagatgagagatacattgac
aaaggaaacaggacatacacatggactccagttaatggcacagattacagtttggccttg
gtattaccaacctacagtttttactatataaaagccaaaatagaagacacaataactcag
gccagatattcagaaacactgaaaccagataattttgaagagtctggctatacctttata
gcaccaagagattactgcaatgaccttaaaatatcagataataacactgagtttctttta
aatttcaatgagtttattgatagaaaaactccaaacgacccatcatgcaacacagatttg
attaatcgagtcttgctggatgcaggctttacaaatgaacttgttcaaaattactggagt
aaacagaaaaacatcaagggagtaaaagcacgttttgttgtgactgatggtggaattacc
agagtttatccaaaggaggctggagaaaattggcaagaaaacccagagacatatgaggac
agcttctataaaaggagtctagataatgataattatgttttcactgctcctaactttaac
aaaactggacctagtgcttatgaatctggcattatggttagcaaagctgtagaaataaat
atccaaggaaaacttcttaaacctgcagttgttggaattaaaattgatataaactcctgg
atcgagaatttcaccaaaacatcaatccgggacccgtgtgctggtccagtttgtgactgc
aaaagaaacagtgatgtaatggattgtgtgattttagatgatggtggatttcttttgatg
gcaaatcatgatgaatacactaaccagattggaagattttttggagagattgatccaagc
ttgatgagacacttgattaatatatcagtttatgcttttaacaaatcctatgactatcag
tcagtgtgtgagcctggagctgcgccgaagcaaggagcagggcatcgctcagcatatgtg
ccatcaatagcagacatactgcacattggctggtgggccactgctgctgcctggtctatt
ctacagcagtttcttttgagtttgagctttccacgactcctcgaagcagctgacatggaa
gaggaggattttacagcctctctgtcgaaacagagctgtattactgaacaaacccaatat
ttctttgacaatgatagtaaatcattcagcggtgtacttgactgtggaaactgttccaga
atctttcatgtagaaaaacttatgaacacgaacttagttttcataatggtggaaagcaaa
gggacttgtccctgtgacactcggcttctcatacaagcagagcagacttctgatggtcca
gatccttgtgacatggttaagcagcccagatatcgaaaagggcctgatgtctgctttgat
aacaatgttctggaggattacactgactgtggtggtgtttctggattaaatccctccctg
tggtctatcattggaatacaatttttactactttggcttttatctggcagtagacactac
cagttatga |
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