KEGG   Sorex fumeus (smoky shrew): 130028330
Entry
130028330         CDS       T10594                                 
Symbol
TLR2
Name
(RefSeq) toll-like receptor 2
  KO
K10159  toll-like receptor 2
Organism
sfum  Sorex fumeus (smoky shrew)
Pathway
sfum04145  Phagosome
sfum04151  PI3K-Akt signaling pathway
sfum04613  Neutrophil extracellular trap formation
sfum04620  Toll-like receptor signaling pathway
sfum05132  Salmonella infection
sfum05134  Legionellosis
sfum05140  Leishmaniasis
sfum05142  Chagas disease
sfum05144  Malaria
sfum05145  Toxoplasmosis
sfum05146  Amoebiasis
sfum05152  Tuberculosis
sfum05161  Hepatitis B
sfum05162  Measles
sfum05168  Herpes simplex virus 1 infection
sfum05169  Epstein-Barr virus infection
sfum05170  Human immunodeficiency virus 1 infection
sfum05171  Coronavirus disease - COVID-19
sfum05205  Proteoglycans in cancer
sfum05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
sfum05321  Inflammatory bowel disease
sfum05323  Rheumatoid arthritis
sfum05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:sfum00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    130028330 (TLR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    130028330 (TLR2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    130028330 (TLR2)
   04620 Toll-like receptor signaling pathway
    130028330 (TLR2)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    130028330 (TLR2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    130028330 (TLR2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    130028330 (TLR2)
   05161 Hepatitis B
    130028330 (TLR2)
   05171 Coronavirus disease - COVID-19
    130028330 (TLR2)
   05162 Measles
    130028330 (TLR2)
   05168 Herpes simplex virus 1 infection
    130028330 (TLR2)
   05169 Epstein-Barr virus infection
    130028330 (TLR2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    130028330 (TLR2)
   05134 Legionellosis
    130028330 (TLR2)
   05152 Tuberculosis
    130028330 (TLR2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    130028330 (TLR2)
   05144 Malaria
    130028330 (TLR2)
   05145 Toxoplasmosis
    130028330 (TLR2)
   05140 Leishmaniasis
    130028330 (TLR2)
   05142 Chagas disease
    130028330 (TLR2)
  09163 Immune disease
   05323 Rheumatoid arthritis
    130028330 (TLR2)
   05321 Inflammatory bowel disease
    130028330 (TLR2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    130028330 (TLR2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sfum04131]
    130028330 (TLR2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sfum04147]
    130028330 (TLR2)
   04054 Pattern recognition receptors [BR:sfum04054]
    130028330 (TLR2)
   04090 CD molecules [BR:sfum04090]
    130028330 (TLR2)
   00536 Glycosaminoglycan binding proteins [BR:sfum00536]
    130028330 (TLR2)
Membrane trafficking [BR:sfum04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    130028330 (TLR2)
Exosome [BR:sfum04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   130028330 (TLR2)
Pattern recognition receptors [BR:sfum04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   130028330 (TLR2)
CD molecules [BR:sfum04090]
 Proteins
  130028330 (TLR2)
Glycosaminoglycan binding proteins [BR:sfum00536]
 Hyaluronan
  Cell surface receptors
   130028330 (TLR2)
SSDB
Motif
Pfam: LRR_8 LRR_4 TIR LRR_1 TIR_2 LRR_LRWD1 LRR_9 LRR_Zer-1 LRR_13 DUF6900
Other DBs
NCBI-GeneID: 130028330
NCBI-ProteinID: XP_055975067
LinkDB
Position
Unknown
AA seq 783 aa
MTRAWWTLWTLGAILILSQEGVSTQTTLSCDPSGICDGRSRDFHSIPSGLTAAVRSLDLS
NNKISFMSKTDLQGCVNLQTLKLRFNEINSIEEDSFRSLGLLEYLDLSYNQLSNLSSSWF
WPLSSLKYLDLRENPYQTLGARPLFSPLTHLRILRIGHRSTFMKIQKTDLAGLMFLEQLE
IEASSLQTYEPTSLASVQHIHYLILHLKQHVWLLEIFMDVFHSVESLELRGTDLKDFHYP
DLPVYKGSSLMRKLTFRGVEATDESFSGLLSLLNHAPGVQEAEFDDCTLYGQGAFYPSEK
QVKAVRSLETLTIRTLRIPKFFLFYDLQSIYSLLGSMKSITIENSKVFLVPCSLSQHLRS
LEYLDLSDNLMVEEYLSNSACEGAWPCLRTLILRANHLTSLEKTATILLTLKNLTKLDIS
KNSFLSMPATCRWPEKINHLNLSSTRMNSLSSCLPATLEVLDVSNNNLHSFSLMLPQLRE
LYLSRNKLKTLPSASCLPALRVLSIRRNMINTFSKEELDPFQELKVLDVGNNNFICSCEF
LSFTREQPGLAQLLRDWPDHYLCDSPTYVRGQRVQDTQLPVTECHLAALVSVTCCILLLL
ILLIVVLCYRFHGLWYLKMTWAWLKAKRKPRRAVPRDICYDAFVSYSEHDSYWVETLMVQ
ELEHFEPPLKLCLHKRDFIPGKWIIDNIIDCIEKSHKTIFVLSASFVKSEWCKYELDFSH
FRLFDENNDAAILVLLEPIEKRAIPQRFCKLRKVMNTKTYLEWPHNEEEQRGFWLSLREA
IKS
NT seq 2352 nt   +upstreamnt  +downstreamnt
atgacacgtgcttggtggacactgtggacattgggggccatcctcatcctctcccaagaa
ggagtctccactcagaccaccctatcttgtgaccccagtggcatctgtgatggccgctct
agagacttccacagcattccctctgggctcacagcagcagtgagaagccttgatctgtcc
aataataagatctccttcatgagcaagactgacctgcagggctgtgtgaacctccagaca
ctgaagttgaggttcaatgaaataaacagcatagaggaagattccttccgttccctgggg
cttcttgaatatttagatttatcctataaccaactatcaaatttatcatcctcctggttc
tggcccttgtcttccttgaaatacctagatttacgagaaaatccttatcagacacttggg
gcaaggcctcttttttctcctctcacccacttgcgaattctgaggattgggcataggtct
actttcatgaagattcagaagacggacttggctgggctgatgttccttgagcaactggag
atcgaggcttccagtctgcagacgtatgagcccacgagcctggcatccgtgcagcatatc
cactacctgattctgcatttgaagcagcacgtttggctgctggaaatattcatggatgtt
ttccattctgtggaatccttggaactgagagggactgacctaaaagacttccactatcca
gacctccctgtctacaaaggcagttccctgatgagaaagctcaccttcagaggcgtagag
gcaaccgatgaaagtttcagtgggctgctgagtctgttgaatcacgccccaggtgtgcag
gaagcagagttcgatgactgcaccctttatggacagggagctttttacccgtctgagaaa
caggtgaaagccgtcaggagcctggagacgctgaccattaggaccctacggatccccaag
ttcttcttattttatgacctgcagagtatctattccctcctgggcagcatgaaaagcatc
acgatagaaaacagcaaggtgttcctggtcccctgctccctttcccagcacctcagatcc
ttggagtacttggatctcagcgacaatctaatggtggaagaatacttgagcaactccgcc
tgtgagggtgcctggccctgcctccgaaccttaattttaagggctaatcatttgacgtcg
ttggaaaagactgcaaccatcctgctgacgctgaaaaatctgaccaagctcgatatcagc
aagaatagttttctttctatgcccgcaacgtgtcgctggcctgaaaagataaaccacctg
aatttatccagcacccggatgaacagtctgagctcctgcctccccgccaccttggaagtg
ttggatgttagcaataacaacctccattccttttctttgatgctgccacagctcagagaa
ctctatctctccagaaacaagttgaagacactccccagcgcctcctgcttacctgccttg
cgagtcctgagcatccgcaggaatatgatcaatactttctccaaggaggaacttgaccct
tttcaagagctgaaggtgttggacgtggggaacaacaattttatttgctcctgtgagttc
ctttctttcacgcgggagcaaccagggctggcccagctcctcagagactggccagatcat
tacctgtgcgactcacccacttacgtgcggggccagcgggttcaggatacacaacttcca
gtcactgagtgtcacctggcagctctggtatccgtcacatgctgcatccttctcctcttg
atcctgctcattgtggttctgtgttaccgtttccatggactgtggtatctgaaaatgacc
tgggcctggctgaaggccaagaggaagccccggagggcagttccaagggacatctgctat
gatgcctttgtgtcctatagcgagcacgactcctactgggtggagaccctcatggtccag
gagctggagcacttcgagccacccttgaagctgtgtctgcacaagcgggacttcatccct
ggcaaatggatcatcgacaacatcattgactgcatcgagaagagccacaaaaccatcttt
gtgctctcggcaagctttgtgaagagcgaatggtgcaagtatgagctggacttctcccat
ttccggctcttcgacgagaacaacgacgctgctattctcgtcctcctggagcccatagag
aagagggccatcccccagcgtttctgtaaactgcgcaaggtcatgaataccaagacctac
ctggagtggccccataatgaagaagagcagcggggcttctggttaagtctgagagaggca
atcaagtcctag

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