Sorex fumeus (smoky shrew): 130028689
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Entry
130028689 CDS
T10594
Symbol
BACE2
Name
(RefSeq) beta-secretase 2
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
130028689 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
sfum01002
]
130028689 (BACE2)
Enzymes [BR:
sfum01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
130028689 (BACE2)
Peptidases and inhibitors [BR:
sfum01002
]
Aspartic peptidases
Family A1: pepsin family
130028689 (BACE2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
130028689
NCBI-ProteinID:
XP_055975489
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All DBs
Position
Unknown
AA seq
501 aa
AA seq
DB search
MALARALLLQLLAQGLLRAAPAPAPLALPLRVAAARAPRPAPRAPGLALALEPAGGPVNF
LAMVDNLQGDSGRGYYLEMQLGTPPQTLQILVDTGSSNFAVAGAPDAYIESFFDSDRSST
FRPKGFDVTVKYTQGSWTGAVGEDVVSIPRGFNRSFLVNVATISESENFFLPGIKWNGIL
GLAYATLAKPSSSLETFFDSLVTQAGIPDVFSMQMCGAGLPVAGTGTNGGSLVLGGIEPS
LYTGDIWYTPIKEEWYYQIEILKLEVGDQSLHLDCREYNADKAIVDSGTTLLRLPQKVFD
AVVEAVARTSLIPEFSDGFWLGSQLACWTNAESPWSYFPKISIYLRGENASTSFRLTILP
QLYIQPMVVASLSYECYRFGISPSSNALVIGATVMEGFYVVFDRARKRVGFASSPCAEVA
GAPVSEISGPFSTDDVASNCVPALPPQDPLLWLVSYALLSVCGLILLVLLALLLLPRPCR
PLRGDAEVVNDESSLVRHRWK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggccctggcgcgcgcgctgctgctgcagctgctggcccaggggctcctgcgcgccgct
ccggctcccgcgcccctggctctgcccctgcgcgtggccgccgcccgtgccccgcgcccc
gcgccccgcgcccccgggctggcgctcgccctggagcccgccggggggcccgtcaacttc
ttggccatggtggacaacctgcagggcgactcaggccgtggctactacctggagatgcag
ctcgggaccccgccgcaaacgctgcagatcctcgtggacacgggcagcagcaacttcgcc
gtggctggagcccctgacgcctacatcgagtccttctttgacagcgaccggtccagcacc
ttccgccccaagggctttgacgtcaccgtcaagtacacgcagggcagctggacgggcgcc
gtcggggaggatgtggtctccatccccagaggcttcaaccgctccttccttgtcaacgtg
gccaccatctctgagtccgagaacttctttctgccggggattaagtggaacgggatcctg
ggcctggcctacgccactctggccaagccttccagctccctggagacattcttcgactct
ctggtgacccaggcgggaatcccagatgtcttctccatgcagatgtgcggagcggggctg
cccgtggctggcaccggtaccaacggaggtagtcttgtcctgggtgggatcgagcccagc
ctgtacacaggagacatctggtacaccccgattaaggaggagtggtactaccagatagag
atcctgaagctggaggtcggagaccagagccttcacctggactgcagggagtacaatgcg
gacaaggccatcgtggacagtgggaccacactgctgcggctgccccagaaagtgtttgac
gccgtggtggaggctgtggcacgcacatccctgattccagaattttccgacggcttctgg
ctgggatcccagctggcctgctggaccaacgcagagagcccgtggtcctacttccccaag
atctccatctacctgcggggcgagaacgccagcacctccttccgcctcaccatcctgcct
cagctttatatccagcccatggtggtggccagcctgagctacgagtgctaccgcttcggc
atctccccgtccagcaacgcgctggtgatcggggccaccgtcatggaaggcttctacgtg
gtcttcgaccgagcgcggaagcgggtgggctttgcctccagtccctgcgcagaggtggca
ggtgcgccagtgtcggagatctccggacccttctccacggacgatgtggcaagtaactgc
gtgcccgcactgcccccgcaggacccactgctgtggctcgtctcctacgcactcctgagc
gtgtgcggcctcatcctcctcgtgctgttggccctcctgctgctgccccggccctgccgc
cccctccggggggatgctgaggtggtcaacgatgagtcctcactggtccggcatcgctgg
aagtga
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