Sorex fumeus (smoky shrew): 130029609
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Entry
130029609 CDS
T10594
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04010
MAPK signaling pathway
sfum04020
Calcium signaling pathway
sfum04151
PI3K-Akt signaling pathway
sfum05200
Pathways in cancer
sfum05216
Thyroid cancer
sfum05223
Non-small cell lung cancer
sfum05230
Central carbon metabolism in cancer
Brite
Enzymes [BR:
sfum01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
130029609 (RET)
Protein kinases [BR:
sfum01001
]
Receptor tyrosine kinases (RTK)
RET family
130029609 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
130029609
NCBI-ProteinID:
XP_055976589
LinkDB
All DBs
Position
Unknown
AA seq
1119 aa
AA seq
DB search
MAKATAGAAGLRFLLLLLQLLGEAALGLYFSRDTYWEKLYVDQKAGMPLLYVHALRDLPE
EVPSFRLGQHLYGAYRTRLHENLWIRIQEDTGLIYLNQSLDHSTWEKLSIRNGGFPQLTV
YLHVYLSPTSQRESECQWPGCARVYFCFMNTSFPTCDGFEVKDLCFPPSDLSFRIRENRP
PGTFYQFRQLPVHSLCPNISVTYQLLEDSRPFRCAPDSLEVSTRWALDREQQEKYQLVAE
CTVRLGSLEKKLMVPCPVVVYDEDDSAPAFLGGVDTASAVVEFKRKEGTVLTTLRVSDAD
VVPASGELLRRYTATLLSSDPWVLQTFRVEHLPNETSVQVNGSSVRETLHDYRLVLNRSV
PISESHTLQLTVLVNDSDFQGPGEGILLLHFNVSVLPISLRLPSPYAFTVSRRASRFAQV
GKVCVENCGEFSGIHVLYKLQAASANCSALGVLTSAEDSSGLLFVNDTEALRRPECAQLQ
YTVVAADRATRRQTQATLTATVEGTYVPEELDCPRSCAVSKRRLECEECGGLGAPSGRCE
WRQGDGRGITRNFSTCSPSIKTCPDGRCDAVENRDLNICPQDCLRGGNIVGGHEPGERRG
IKAGFGICNCFPDDKKCFCEPEDSQELLCDELCRMVVVAAVLCSLIASVLLAIFCIHRFH
KNAPKPPIASAEMTFRRPTQAFPVSYSSSGARRPSLDSMENQVSVDAFKIPEDPKWEFPR
KNLILGKTLGEGEFGKVVQATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLKQ
VNHPQVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKAGPGYVGGSSSGGSRGSRNS
SYLDNPDERALTMGDLISFAWQISRGMQYLAEMKLVHRDLAARNVLVAEGRKMKISDFGL
SRDVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGI
PPERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDY
LDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPV
PHTRADGTNSGCPRYANDSVYANWMVSPSAAQLMDSFDS
NT seq
3360 nt
NT seq
+upstream
nt +downstream
nt
atggcgaaggcgacggccggcgccgcggggctgcggttcctgctgctgctgctgcagctg
cttggggaagccgctctgggactctacttctccagggacacttactgggagaagctgtac
gtggaccagaaggcgggcatgcccctgctctacgtgcatgccctgcgtgacctccccgag
gaggtgcccagcttccggctgggccagcacctctacggtgcctaccgcacgcggctgcac
gagaacctctggatccgcatccaggaggacacgggcctcatctacctgaaccagagcctg
gaccacagcacctgggagaagctcagcatccgcaatggaggcttcccccaactcactgtc
taccttcacgtctacctgtcacccacatcccagcgggaaagcgaatgccagtggccgggg
tgcgcccgagtgtacttctgcttcatgaacacctccttccccacgtgcgatggctttgaa
gtcaaggatctctgcttccccccgtcagatctctccttccgcatccgggagaacaggccc
ccgggaaccttctatcagtttcgccagctgcccgtgcactccctgtgcccgaacatcagt
gtgacttaccagctcctggaagacagcagacccttccgctgcgcgcccgacagtctggag
gtgagcacgcgctgggcgctggaccgcgagcagcaggagaagtaccagctggtggccgag
tgcaccgtgcgcctgggctcgctggagaagaagttaatggtgccctgccccgtggtcgtg
tacgacgaggacgactcggcgccggccttcctcgggggcgtggacaccgccagtgccgtg
gtggagttcaagcggaaggagggcaccgtgctgactacactccgcgtttccgatgctgat
gtggtgccggcatctggggagctgctgaggcgctacacggccacgctgctgtccagcgac
ccctgggtcctacagaccttccgcgtggagcacctgcccaacgagacctcagtgcaggtc
aacggcagctcggtgcgggagaccctgcacgattacaggctggttctcaaccgcagtgtc
cccatctcggagagccacaccctacagctcactgtgctggtcaatgactcggacttccag
ggcccaggggagggcatcctcctgctccacttcaacgtgtccgtgctgcccatcagcctg
cgccttcccagcccctacgccttcactgtcagcaggagggccagccgctttgcccaggtt
ggaaaagtatgtgtggaaaactgcggggagttcagcggcatccacgtgctgtacaagctc
caggcggccagcgccaactgcagtgccctgggcgtgctcacctccgccgaggactcctca
gggctcctgttcgtgaacgacactgaggctctgcggcgacccgagtgtgcccagctacag
tacacggtggtggccgccgaccgcgccacccgcaggcagacccaggccacgctcacggcc
accgtggaggggacgtatgtgcctgaggagctggactgccccaggtcgtgtgcagtgagc
aagcggcggctggagtgtgaggagtgcggcgggctgggtgctccgagtggccggtgcgag
tggaggcagggagacggcagagggatcacccggaacttctctacctgctcccccagcatc
aagacgtgtcccgatggccgctgcgatgccgtggagaacagagacctcaacatctgcccc
caggactgcctccggggcggcaacatcgttggtgggcatgagccaggggagcgtcgtggc
atcaaagccggctttggcatctgcaactgcttcccagacgacaagaagtgcttctgcgag
ccggaggacagccaggagctgctgtgtgacgagctttgccgcatggtggtcgtggcggcc
gtgctctgctccctgatcgcgtcggtgctgctggccatcttctgcatccatcgcttccac
aagaacgcccccaagccgcccatcgcctcggccgagatgaccttccgccggcccacccag
gccttccctgtcagctactcctcgtccggcgcccgccggccctcgctcgactccatggag
aaccaggtctctgtggatgccttcaagatcccggaggatccaaagtgggaattcccccgg
aagaacttaattcttgggaaaacactgggagaaggcgaatttgggaaagtggtccaggca
acggccttccggctgaaaggcaaagcgggctacaccacagtggccgtgaagatgctgaaa
gaaaacgcctccccaagcgagctgcgggatctgctgtccgaattcaacctcctgaagcag
gtcaaccacccccaggtcatcaagctctacggggcctgcagccaggacgggccgctcctc
ctcatcgtggagtacgctaagtacggctccctgcggggcttcctccgggagagccgcaaa
gcggggccaggctacgtgggcggcagcagcagcgggggcagccggggcagccgcaactcc
agctacctggacaacccggatgagcgggcgctgaccatgggcgacctcatctcttttgcc
tggcagatctctcggggcatgcagtacctggccgagatgaagctcgttcatcgggacctg
gcggccaggaacgtcctggtcgctgagggccggaagatgaagatttcagattttggcctg
tcccgagacgtctatgaagaggactcctatgtcaagaggagcaagggccggattccagtt
aaatggatggcgatcgagtccctcttcgatcatatctacaccacccagagtgatgtgtgg
tccttcggggttctgctgtgggagattgtgaccctggggggcaacccataccctgggatc
cctccggagaggctcttcaaccttctgaagacgggctaccggatggagcgacctgacaac
tgcagcgaggagatgtacggtctcatgttgcagtgttggaagcaggaaccagacaagaga
cctgtgtttgctgacattagcaaagacctagagaagatgatggtgaagagccgagactat
ttggacctggctgcatccacaccttctgattccctgctttatgacgatggtctctcggag
gaggagacacccctggtggactgtaataatgctcccctccctcgagccctcccttccacg
tggattgaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcctgta
ccacacacgagagccgatggcactaacagtgggtgtccacgctatgcaaatgatagtgtt
tatgctaactggatggtttcaccctcagcggcacagttaatggactcgtttgatagttaa
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