Sorex fumeus (smoky shrew): 130030027
Help
Entry
130030027 CDS
T10594
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
sfum Sorex fumeus (smoky shrew)
Pathway
sfum04120
Ubiquitin mediated proteolysis
sfum04144
Endocytosis
sfum04330
Notch signaling pathway
sfum04668
TNF signaling pathway
sfum04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
sfum00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
130030027 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
130030027 (ITCH)
04668 TNF signaling pathway
130030027 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
130030027 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
130030027 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
sfum04131
]
130030027 (ITCH)
04121 Ubiquitin system [BR:
sfum04121
]
130030027 (ITCH)
Enzymes [BR:
sfum01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
130030027 (ITCH)
Membrane trafficking [BR:
sfum04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
130030027 (ITCH)
Ubiquitin system [BR:
sfum04121
]
Ubiquitin ligases (E3)
HECT type E3
130030027 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
130030027
NCBI-ProteinID:
XP_055977077
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYDTLKSNNMKFEEVVITL
QLVGDKEPTETIGDLSICLDGMQLESEVVTSGETTGSESASQNDDGSRSKDETRVNTSGS
DDPEDAGSGENRRASGNNSPSLSNGGFKPARPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTTSSTSEGAASGLIIPLTISGGSGPRPLNTVPQAPLPPGWEQRVDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDNNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLAMPQHTKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagcctgaccatgaaatcacaactt
caaatcactgttatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagtcacagttgatggacagtcaaagaagacagaaaagtgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcacccctgtgagtaaattacat
tttcgtgtgtggagccaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgacacattaaaatcaaacaatatgaaatttgaggaagttgttataacttta
cagcttgtaggtgacaaagaaccaacagaaacaataggagacttatcaatttgtcttgat
ggaatgcaactagaatctgaagttgttaccagtggtgaaactactggttcagaaagtgct
tcccagaatgatgatggttccagatccaaggatgaaaccagagtgaatacaagtggatca
gatgacccagaagatgcaggatctggtgaaaataggagggccagtgggaataattctcca
tcactctcaaatggcggttttaagcctgctaggcctccaagaccttcacgaccacctcct
cctaccccacgtagaccagcatctgttaatggttcaccatctgccacttctgaaagtgat
ggatctagtactggatctctgccaccaacaaatacaacttccagtacatctgaaggagca
gcttctggattaataattcctcttactatatccggaggttcaggccctagaccactaaat
actgttcctcaagctcccctcccacctggttgggaacaaagagtggaccagcatggacga
gtttactatgttgatcatattgaaaagagaaccacgtgggatagaccagaacctctacct
cctgggtgggaacgacgggttgataatatgggtcgtatttattatgttgatcatttcaca
agaacaacaacttggcagaggccaactttagaatctgtccggaactatgaacagtggcag
ctccaacgtagtcaacttcagggagcaatgcagcagtttaaccagaggttcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcctcttggtcccttgcca
cctggatgggagaagagaacggacaacaatggtagagtatattttgtgaaccacaatact
cgtataacccaatgggaagaccccagaagtcaaggccaattaaatgaaaaacccttacct
gaaggctgggaaatgagattcacagtggatggaattccttattttgtggatcataataga
agaactaccacctatatagatccccgcacaggaaaatctgccctagacaatggcccccag
atagcctatgtacgggacttcaaggcaaaggttcaatatttccgtttctggtgtcagcaa
ctggccatgccacagcacacaaagattacagtgacaagaaaaacattgtttgaggattcc
tttcaacagataatgagcttcagtcctcaagatctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtct
catgaagtgttgaacccaatgtattgcctgtttgaatatgcaggaaaggataactactgc
ttgcaaataaaccctgcttcttatatcaatccagatcatctgaaatattttcgttttatt
ggcagatttattgccatggctctgttccatgggaagttcatagacacgggtttttcttta
ccgttctataagcgtatcttgaacaaaccagttgggctcaaggatttagaatccattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatatcgaagaatgtggtttg
gaaatgtacttctctgtagataaagaaattttaggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaggaatatatcagaatggta
gctgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcaatactttgatgcaaaggaactagaggttctt
ttatgtggaatgcaagagattgatttgaatgattggcaaagacatgctatctaccgtcat
tatactagaacaagcaaacaaatcatgtggttctggcagtttgttaaagaaattgataat
gagaaaagaatgagacttctgcagtttgttactggaacctgccgactaccagttggagga
tttgctgacctcatggggagtaatggaccacagaaattttgcattgaaaaagttggaaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccatataaa
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagaataa
DBGET
integrated database retrieval system
